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Hong, Seung-Hwan,Jang, Min-Seok,Cho, Sung June,Ahn, Wha-Seung The Royal Society of Chemistry 2014 Chemical communications Vol.50 No.38
<P>Mesoporous chabazite ion-exchanged with Ca<SUP>2+</SUP> was effective for CO<SUB>2</SUB> capture at 20 bar and 473 K, whereas 13X as a support material enabled recyclable carbonation of <I>ca.</I> 8 wt% Mg(OH)<SUB>2</SUB> approaching the theoretical maximum for CO<SUB>2</SUB> capture with 10% H<SUB>2</SUB>O.</P> <P>Graphic Abstract</P><P>Mesoporous chabazite ion-exchanged with Ca<SUP>2+</SUP> was effective for CO<SUB>2</SUB> capture at 20 bar and 473 K, whereas 13X as a support material enabled recyclable carbonation of <I>ca.</I> 8 wt% Mg(OH)<SUB>2</SUB> approaching the theoretical maximum for CO<SUB>2</SUB> capture with 10% H<SUB>2</SUB>O. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3cc46313c'> </P>
A High Efficiency Controller IC for LLC Resonant Converter in 0.35 μm BCD
Hong, Seong-Wha,Kim, Hong-Jin,Park, Hyung-Gu,Park, Joon-Sung,Pu, Young-Gun,Lee, Kang-Yoon The Korean Institute of Power Electronics 2011 JOURNAL OF POWER ELECTRONICS Vol.11 No.3
This paper presents a LLC resonant controller IC for secondary side control without external active devices to achieve low profile and low cost LED back light units. A gate driving transformer is adopted to isolate the primary side and the secondary side instead of an opto-coupler. A new integrated dimming circuitry is proposed to improve the dynamic current control characteristic and the current density of a LED for the brightness modulation of a large screen LCD. A dual-slope clock generator is proposed to overcome the frequency error due to the under shoot in conventional approaches. This chip is fabricated using 0.35 ${\mu}m$ BCD technology and the die size is $2{\times}2\;mm^2$. The frequency range of the clock generator is from 50 kHz to 500 kHz and the range of the dead time is from 50 ns to 2.2 ${\mu}s$. The efficiency of the LED driving circuit is 97 % and the current consumption is 40 mA for a 100 kHz operation frequency from a 15 V supply voltage.
Hong, Soon-Pyo,Yang, Joon-Seung,Han, Jung-Yeon,Ha, Sung-Il,Chung, Joong-Wha,Koh, Young-Youp,Chang, Kyong-Sig,Choi, Dong-Hyun Pharmaceutical Society of Great Britain 2011 Journal of pharmacy and pharmacology Vol.63 No.1
<P>The purpose of this study was to examine the effects of lovastatin on cytochrome P450 (CYP) 3A4 and P-glycoprotein (P-gp) in vitro and then to determine the effects of lovastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, in rats.</P>
Hydroxyl Radical Generation on Bubble Surface of Aqua-Plasma Discharge
Sung-Young Yoon,Sang-Heun Lee,Jung Wha Hong,Woo Seok Kang,Youn-Chang Jang,Gon-Ho Kim IEEE 2011 IEEE transactions on plasma science Vol.39 No.11
<P>The location of hydroxyl radical (OH<SUP>*</SUP>) generation in aqua plasma is investigated with the images of vapor bubble discharge in a conductive electrolyte (saline). A comparison of the visible-and UV-ray data taken from the Na<SUP>+*</SUP> and radical OH<SUP>*</SUP> reveals that Na<SUP>+*</SUP> is generated in both volume and surface of bubble while most of OH<SUP>*</SUP> is observed at the vapor surface. This result implies that the steamer-type of aqua plasma was generated in the vapor bubble covered over a metal electrode tip, and the charged particles disperse along the surface of the vapor bubble.</P>
Development of PNA-Array Platforms for Detection of Genetic Polymorphism of Cytochrome P450 2C19
Hong, Dae-Wha,Park, Hyung-Ju,Chi, Young-Shik,Lee, Young,Lee, Jun-O,Kang, Hyo-Jin,Park, Dae-Keun,Chung, Sang-J.,Yun, Wan-Soo,Choi, In-Sung S. Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.suppl8
( Sung Wook Yang ),( Jung Wha Chung ),( Sang Soo Lee ),( Sukho Hong ),( Seong Min Chung ),( Eun Sun Jang ),( Jin Wook Kim ),( Sook Hyang Jeong ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1
Background: Serum level of alpha-fetoprotein (AFP) can elevate in patients with chronic hepatitis B (CHB) without evidence of hepatocellular carcinoma. However, the response of AFP levels to oral nucleos(t)ide analog is not elucidated yet. In this study, we retrospectively assessed the prevalence of high serum AFP levels in CHB patients who were treated with entecavir (ETV), and patterns of AFP changes during the entecavir therapy. Methods: A total of 110 CHB patients who started ETV as an initial antiviral therapy were enrolled in this retrospective study. Pre-treatment clinical , biochemical and virologic parameters were evaluated in relation to the serial AFP levels. Results: The mean baseline AFP value was 41.2 ng/dL. Before ETV therapy (range: 1.3-840 ng/dL). Among the 110 patients, fourty-six (41.8%) showed high pre-treatment AFP values (>10 ng/dl). In the high AFP group, Aspartate transaminase (AST), Alkaline phosphatase (ALP), bilirubin, albumin and prothrombin time (PT) were significantly higher compared to normal AFP group (P=0.021, 0.005, 0.000, 0.001 and 0.004, respective). Only baseline albumin level was significant predictor of high AFP level in multivariate logistic regression analysis (P=0.043, HR=0.00). In high AFP group, The cumulative normalization rates of AFP levels were 26.1%, 73.9% and 91.3% at 18, 36 and 72 weeks, respectively. Serum DNA level was significantly correlated to the time to AFP normalization in a Kaplan-Meier analysis (P=0.039). Conclusions: AFP frequently elevates in CHB patients who undergoes oral nucleoside analog therapy, and baseline albumin level was significantly associated with high AFP level. Normalization of AFP is delayed and about 1/3 shows high AFP levels up to 3 years of ETV therapy. Baseline DNA level was associated with delayed AFP normalization after ETV therapy.