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Image Registration of Vertebral Region from CT Images Based on Salient Region Feature
Suguru SATO,Huimin LU,Joo Kooi TAN,Hyoungseop KIM,Seiichi MURAKAMI,Midori UENO,Takashi TERASAWA,Takatoshi AOKI 제어로봇시스템학회 2017 제어로봇시스템학회 국제학술대회 논문집 Vol.2017 No.10
In recent years, the development of the computer-aided diagnosis (CAD) systems to support radiologist is attracting attention in medical research field. Temporal subtraction technique, which is one of CAD, is a technique to generate images emphasizing temporal changes in lesions by performing a differential operation between current and previous image of the same subject. In this paper, we propose an image registration method for image registration of current and previous image, to generate temporal subtraction images from CT images and enhanced bone metastasis region. The proposed registration method is composed into three main steps: i) segmentation of the region of interest (ROI) using graph cut, ii) use global image matching to select pairs from previous and current image, and iii) final image matching based on salient region feature. We perform our proposed method to synthesis and satisfactory registration experiments. The rotated synthesis image give TP 100.0[%] and FP 12.16[%]. The synthesis image obtained by applying a Gaussian filter give TP 70.40[%] and FP 0.00[%]. The synthesis image obtained by adding artificial pseudo lesion region give TP 99.45[%] and FP 17.89[%]. The synthesis image obtained by adding random noise of 5[%], which gave TP 83.05[%] and FP 16.95[%].
Enhancement of Bone Metastasis from CT Images Based on Salient Region Feature Registration
Suguru Sato,Huimin Lu,Hyoungseop Kim,Seiichi Murakami,Midori Ueno,Takashi Terasawa,Takatoshi Aoki 제어로봇시스템학회 2018 제어로봇시스템학회 국제학술대회 논문집 Vol.2018 No.10
In recent years, the development of the computer-aided diagnosis (CAD) systems to support radiologist is attracting attention in medical research field. One of them is temporal subtraction technique. It is a technique to generate images emphasizing temporal changes in lesions by performing a differential operation between current and previous image of the same subject. In this paper, we propose an image registration method for image registration of current and previous image, to generate temporal subtraction images from CT images and enhanced bone metastasis region. The proposed registration method is composed into three main steps: i) automatic segmentation of the region of interest (ROI) using position information of the spine based on biology, ii) use global image matching to select pairs from previous and current image, and iii) final image matching based on salient region feature. We perform registration technique on synthetic data and confirm usefulness of the proposed method. Furthermore, radiologist conduct comparative experiments without and with temporal subtraction images created by proposed method. As a result, they show high reading performance by using temporal subtraction images.
Yuichi Sato,Hirotoshi Hatori,Suguru Igarashi,Manabu Arai,Kazuki Ito,Syota Kikuchi 한국물리학회 2010 Current Applied Physics Vol.10 No.3
Cadmium telluride (CdTe) thin films were grown on sapphire c-face single-crystal substrates by vacuum evaporation. Prior to growing the CdTe thin films, conducting thin films of Ni, Mo, Ti and titanium nitride (TiN) were grown on the sapphire substrates. The crystallinities and photoluminescence (PL) properties of the CdTe thin films grown on the various conducting thin films were investigated and they were compared with those of CdTe thin films grown directly on sapphire substrates without a conducting thin film. CdTe thin films with relatively high crystallinities were obtained when Ti and TiN were used as the conducting thin film. Therefore, the PL properties of the CdTe thin films on such conducting thin films were not inferior to those of the CdTe thin film grown directly on the sapphire substrate. The effect of the Cd and Te supply ratio on the properties of the CdTe thin films was also investigated. The CdTe thin films had much higher crystallinities when they were grown in Te-rich conditions than in Cd-rich conditions.
Fu Namai,Suguru Shigemori,Tasuku Ogita,Takashi Sato,Takeshi Shimosato 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-
The increased incidence of inflammatory bowel disease (IBD) in Western and rapidly Westernizing developing countries poses a global pandemic threat. The development of affordable drugs for treating IBD worldwide is thus a priority. Genetically modified lactic acid bacteria (gmLAB) as microbial therapeutics are inexpensive protein producers suitable for use as carriers of protein to the intestinal mucosa. Here, we successfully constructed gmLAB hypersecreting interleukin 1 receptor antagonist (IL-1Ra). Oral administration of these gmLAB suppressed body weight reduction and exacerbation of the disease activity index score in mice with acute colitis and decreased the number of CD4+ IL-17A+ cells in the mesenteric lymph nodes. These data suggest that the gmLAB deliver IL-1Ra to the colon, where it inhibits IL-1 signaling. We thus developed a novel IBD therapeutic that blocks IL-1 signaling using a gmLAB protein delivery system. This system could be an inexpensive oral microbial therapeutic.
S.-J. Lee,Suguru Sato,Tomohiko Niizeki,Hideto Yanagihara,Eiji Kita,Chiharu Mitsumata 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.3
A numerical simulation of magnetic materials with random magnetic anisotropy was performed. The magnetization of an assembly of magnetically-interacting grains with randomly-oriented uniaxialanisotropy was calculated using the Landau-Lifshitz-Gilbert equation. For simplicity in thesimulation, the magnetizations in a grain were assumed to be aligned in the same direction; thisassumption is known as the single spin model. The interaction at the interface of the grains wastaken into account by including an interaction energy between the unit vectors that represent themagnetization directions of the grains. Calculations were carried out for an N × N × N system,where the grain sizes D ranged from 5 to 40 nm and N ranged from 10 to 80. The relation betweenthe coercive forces HC and the grain size is represented by HC ~ Dk. For the case of N = 10,k = 5.7, which corresponds to the primitive theory of the random anisotropy model (RAM) wherek = 6. As N increased, k decreased slightly from 5.7 to 4.2. The gradient of the log-log plot of thecoercive force versus the grain size (d logHC/d logD) was deduced by smoothing the data and wasfound to have a peak value of approximately 6. This result suggests that the RAM is supported bythe simulation within the range of grain sizes where the peak was observed.
Yousuke Nakai,Tatsuya Sato,Ryunosuke Hakuta,Kazunaga Ishigaki,Kei Saito,Tomotaka Saito,Naminatsu Takahara,Tsuyoshi Hamada,Suguru Mizuno,Hirofumi Kogure,Minoru Tada,Hiroyuki Isayama,Kazuhiko Koike 거트앤리버 소화기연관학회협의회 2020 Gut and Liver Vol.14 No.3
Endoscopic management of bile duct stones is now the standard of care, but challenges remain with difficult bile duct stones. There are some known factors associated with technically difficult bile duct stones, such as large size and surgically altered anatomy. Endoscopic mechanical lithotripsy is now the standard technique used to remove large bile duct stones, but the efficacy of endoscopic papillary large balloon dilatation (EPLBD) and cholangioscopy with intraductal lithotripsy has been increasingly reported. In patients with surgically altered anatomy, biliary access before stone removal can be technically difficult. Endotherapy using two new endoscopes is now utilized in clinical practice: enteroscopy-assisted endoscopic retrograde cholangiopancreatography and endoscopic ultrasound-guided antegrade treatment. These new approaches can be combined with EPLBD and/or cholangioscopy to remove large bile duct stones from patients with surgically altered anatomy. Since various endoscopic procedures are now available, endoscopists should learn the indications, advantages and disadvantages of each technique for better management of bile duct stones.
Cacao bean husk: an applicable bedding material in dairy free-stall barns
Akira Yajima,Hisashi Owada,Suguru Kobayashi,Natsumi Komatsu,Kazuaki Takehara,Maria Ito,Kazuhide Matsuda,Kan Sato,Hisao Itabashi,Satoshi Sugimura,Shuhei Kanda 아세아·태평양축산학회 2017 Animal Bioscience Vol.30 No.7
Objective: The objectives of the study were to assess the effect of cacao bean husk as bedding material in free-stall barn on the behavior, productivity, and udder health of dairy cattle, and on the ammonia concentrations in the barn. Methods: Four different stall surfaces (no bedding, cacao bean husk, sawdust, and chopped wheat straw) were each continuously tested for a period of 1 week to determine their effects on nine lactating Holstein cows housed in the free-stall barn with rubber matting. The lying time and the milk yield were measured between d 4 and d 7. Blood samples for plasma cortisol concentration and teat swabs for bacterial counts were obtained prior to morning milking on d 7. The time-averaged gas-phase ammonia concentrations in the barn were measured between d 2 and d 7. Results: The cows spent approximately 2 h more per day lying in the stalls when bedding was available than without bedding. The milk yield increased in the experimental periods when cows had access to bedding materials as compared to the period without bedding. The lying time was positively correlated with the milk yield. Bacterial counts on the teat ends recorded for cows housed on cacao bean husk were significantly lower than those recorded for cows housed without bedding. Ammonia concentration under cacao bean husk bedding decreased by 6%, 15%, and 21% as compared to no bedding, sawdust, and chopped wheat straw, respectively. The cortisol concentration was lowest in the period when cacao bean husk bedding was used. We observed a positive correlation between the ammonia concentrations in the barn and the plasma cortisol concentrations. Conclusion: Cacao bean husk is a potential alternative of conventional bedding material, such as sawdust or chopped wheat straw, with beneficial effects on udder health and ammonia concentrations in the barns.