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      • KCI등재

        3분과 : 가선집재작업에서의 작업 생산성 및 비용 분석

        한원성 ( Won Sung Han ),한한섭 ( Han Sup Han ),김남훈 ( Nam Hun Kim ),차두송 ( Du Song Chu ),조구현 ( Koo Hyun Cho ),민도홍 ( Do Hong Min ),권기철 ( Ki Cheol Kwon ) 한국임학회 2014 한국산림과학회지 Vol.103 No.1

        본 연구에서는 임목수확작업에 사용되는 집재기계의 작업효율성을 분석하여 경사가 급한(20° 이상) 작업조건에 적합한 가선계 집재기계를 선정하는데 기초 정보를 제공하고자, 타워야더(RME-300T), 트랙터부착형 집재기(일명: 춘천집재기), 트랙터윈치(FARMI) 등에 의한 집재작업에서의 작업생산성 및 비용을 비교 분석하였다. 평균 흉고직경이 20 cm, 집재거리 60 m, 가로집재거리 10 m, 그리고 기계이용률이 70%인 동일한 작업 조건에서 작업이 이루어질 경우, 타워야더의 1일 집재작업 생산성은 33.04 m3/일, 트랙터부착형 집재기는 38.47 m3/일, 그리고 트랙터윈치는 14.17 m3/일으로 분석되었으며, 이에 따른 집재작업비용은 각각 25,105원/m3, 20,520원/m3, 37,835원/m3으로 나타났다. 동일한 작업조건에서 집재거리에 따른 각 집재기계별 작업효율성을 비교하였을 경우, 집재거리가 40 m 이내로 짧을 경우에는 트랙터윈치에 의한 집재작업이 효율적이며, 40~140 m의 집재거리에서는 춘천집재기가, 140 m 이상의 장거리 집재작업에서는 타워야더가 가장 효율적인 것으로 나타났다. This study was conducted to provide field-based harvesting study information which can be used to select an optimal cable system for certain work conditions on steep grounds (>20° ground slope) in Korea. Toaccomplish this study objectives, we evaluated three cable yarding systems (RME-300T tower-yarder, Chuncheontower-yarder, FARMI tractor winch) working in typical work conditions for their yarding productivity and operational efficiency. Those yarders are commonly used for removing logs or trees on steep grounds in Korea. Under the same work conditions (average DBH of tree to be cut, 20 cm; yarding distance, 60 m; lateral yardingdistance, 10 m; and machine utilization rate, 70%), the average productivities were 33.04 m3/day, 38.47 m3/day, and 14.17 m3/day for RME-300T, Chuncheon tower-yarder, and FARMI, respectively. Our standardized cost comparison study also showed that the yarding cost was highest at 37,835 won/m3 with FARMI, followed byRME-300T at 25,105 won/m3 for the same work conditions. We found the lowest yarding cost with the Chuncheon tower-yarder at 20,520 won/m3 which was resulted primarily from high yarding productivity at theyarding distance (60 m). Our analysis suggested that a small machine such as FARMI could be a low-costyarding machine option for a cable yarding job with a short yarding distance (40 m or less). The Chuncheontower-yarder is well suited for a mid-range yarding distance job in Korea, ranged between 40 to 140 m. Ifyarding distance were longer than 140 m, the RME-300T tower yarder appears to be most cost-effective.

      • KCI등재

        Long-term postresection prognosis of primary neuroendocrine tumors of the liver

        Jay Jung,Shin Hwang,Seung-Mo Hong,Ki-Hun Kim,Chul-Soo Ahn,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Yo-Han Park 대한외과학회 2019 Annals of Surgical Treatment and Research(ASRT) Vol.97 No.4

        Purpose: Primary hepatic neuroendocrine tumor (PHNET) is a very rare neoplasm, requiring strict exclusion of metastasis from possible extrahepatic primary sites for its diagnosis. Methods: We reviewed our clinical experience of 13 patients with primary hepatic NET who underwent liver resection from January 1997 to December 2015. Results: The mean age of the 13 patients (8 males and 5 females) was 51.1 ± 12.8 years; the most common clinical manifestation was vague, nonspecific abdominal pain (n = 9). Of them, 11 patients underwent preoperative liver biopsy, 7 of which correctly diagnosed as neuroendocrine tumor (NET). Ten patients underwent R0 resection, and 3 underwent R1 resection. Diagnosis of PHNET was confirmed both immunohistochemically and by absence of extrahepatic primary sites. All tumors were single lesions, with a mean size of 9.6 ± 7.6 cm and a median size of 4.3 cm; all showed positive staining for synaptophysin and chromogranin. During a mean follow-up period of 95.1 ± 86.6 months, 7 patients died from tumor recurrence, whereas the other 6 remain alive to date, making the 5-year tumor recurrence rate 56.0% and the 5-year patient survival rate 61.5%. When confined to R0 resection, 5-year recurrence and survival rates were 42.9% and 70.0%, respectively. Univariate analysis showed that Ki-67 proliferative index was the only risk factor for tumor recurrence. Conclusion: PHNET is a very rare tumor with no specific clinical features, and its final diagnosis depends primarily on pathology, immunohistochemistry, and exclusion of metastasis from other sites. Aggressive surgical treatment is highly recommended for PHNET because of acceptably favorable postresection outcomes

      • Benzyl Isothiocyanate Inhibits Prostate Cancer Development in the Transgenic Adenocarcinoma Mouse Prostate (TRAMP) Model, Which Is Associated with the Induction of Cell Cycle G1 Arrest

        Cho, Han Jin,Lim, Do Young,Kwon, Gyoo Taik,Kim, Ji Hee,Huang, Zunnan,Song, Hyerim,Oh, Yoon Sin,Kang, Young-Hee,Lee, Ki Won,Dong, Zigang,Park, Jung Han Yoon MDPI 2016 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.17 No.2

        <P>Benzyl isothiocyanate (BITC) is a hydrolysis product of glucotropaeolin, a compound found in cruciferous vegetables, and has been shown to have anti-tumor properties. In the present study, we investigated whether BITC inhibits the development of prostate cancer in the transgenic adenocarcinoma mouse prostate (TRAMP) mice. Five-week old, male TRAMP mice and their nontransgenic littermates were gavage-fed with 0, 5, or 10 mg/kg of BITC every day for 19 weeks. The weight of the genitourinary tract increased markedly in TRAMP mice and this increase was suppressed significantly by BITC feeding. H and E staining of the dorsolateral lobes of the prostate demonstrated that well-differentiated carcinoma (WDC) was a predominant feature in the TRAMP mice. The number of lobes with WDC was reduced by BITC feeding while that of lobes with prostatic intraepithelial neoplasia was increased. BITC feeding reduced the number of cells expressing Ki67 (a proliferation marker), cyclin A, cyclin D1, and cyclin-dependent kinase (CDK)2 in the prostatic tissue. <I>In vitro</I> cell culture results revealed that BITC decreased DNA synthesis, as well as CDK2 and CDK4 activity in TRAMP-C2 mouse prostate cancer cells. These results indicate that inhibition of cell cycle progression contributes to the inhibition of prostate cancer development in TRAMP mice treated with BITC.</P>

      • SCIESCOPUSKCI등재

        Tracking Position Control of DC Servo Motor in Lon Works/IP Network

        Ki-Won Song,Gi-Sang Choi,Gi-Heung Choi 대한전기학회 2008 International Journal of Control, Automation, and Vol.6 No.2

        The Internet's low cost and ubiquity present an attractive option for real-time distributed control of processes on the factory floor. When integrated with the Internet, the Lon Works open control network can give ubiquitous accessibility with the distributed control nature of information on the factory floor. One of the most important points in real-time distributed control of processes is timely response. There are many processes on the factory floor that require timely response. However, the uncertain time delay inherent in the network makes it difficult to guarantee timely response in many cases. Especially, the transmission characteristics of the Lon Works/IP network show a highly stochastic nature. Therefore, the time delay problem has to be resolved to achieve high performance and quality of the real-time distributed control of the process in the LonWorks/IP Virtual Device Network (VDN). It should be properly predicted and compensated. In this paper, a new distributed control scheme that can compensate for the effects of the time delay in the network is proposed. It is based on the PID controller augmented with the Smith predictor and disturbance observer. Designing methods for output feedback filter and disturbance observer are also proposed. Tracking position control experiment of a geared DC Servo motor is performed using the proposed control method. The performance of the proposed controller is compared with that of the Internal Model Controller (IMC) with the Smith predictor. The result shows that the performance is improved and guaranteed by augmenting a PID controller with both the Smith predictor and disturbance observer under the stochastic time delay in the LonWorks/IP VDN.

      • KCI등재

        Precision Laser Diffractometry for Grating Period Measurement

        Won Young Song,Byong Chon Park,Beom-hoan O,Ki Young Jung 한국물리학회 2004 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.45 No.3

        A conventional-type precision laser diractometer has been developed for grating pitch measurements, and a successful precision improvement has been achieved. As the accuracy depends on the accuracies of the laser wavelength, the goniometer, and the diraction angle determination, the improved system adopts a precision goniometer, a position-sensitive detector, and more precise values for the laser wavelength and the focusing lens. The lens was inserted between the grating specimen and the detector in order to minimize the errors due to the linear and the angular shifts of the diracted beam and due to the shift in the grating plane o the rotational axis of the arm. The modications contribute a lot to improving the accuracy of the measurement. The measured pitch values for the lamella-structure gratings certied as 288 nm and 700 nm by the manufacturer were 287.591 0.004 and 700.758 0.012 nm, respectively, where expanded uncertainties with a coverage factor of 2.

      • KCI등재

        Comparisons of C-kit, DOG1, CD34, PKC-θ and PDGFR-α Expressions in Gastrointestinal Stromal Tumors According to Histopathological Risk Classification

        ( Ki-sung Kim ),( Hye-jung Song ),( Won-sub Shin ),( Kang-won Song ) 대한임상검사과학회 2011 대한임상검사과학회지(KJCLS) Vol.43 No.2

        Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor and is associated with a specific immunophenotype index. It is very important to identify the specific immunophenotype and the diagnosis for the treatment GIST patients. Ninety two cases of GIST analyzed in this study were immuno-stained for c-kit, DOG1, CD34, PKC-θ, PDGFR-α. The rate of positive staining and statistical significance were then compared. In addition, the GISTs were analyzed as followings: very low risk, low risk, intermediate risk and high risk according to tumor size and nuclear division, and later correlated with clinical parameters. The results of the GIST positive stainings were: DOG1 (95.7%), PKC-θ (90.2%), PDGFR-α (88.0%), c-kit (87.0%) and CD34 (71.7%). Only DOG1 staining showed a statistical significance of p<0.05. It was identified in the classification system of histologic risk that staining expression of DOG1, PKC-θ, PDGFR-α were significantly increased as histologic risk increases (p<0.05). However, clinical parameters such as age and sex of patients have no correlations with the classification system of histologic risk (p>0.05). Therefore, in this study, the expression of DOG1 showed statistical significance and DOG1, PKC-θ, PDGFR-α staining increased significantly as the histologic risk increases in histologic classification system. Taken together, the DOG1 staining should be very effective for the diagnosis of GIST patients.

      • The Wild Relatives of Wheat Grain Proteome

        Ki-Hyeon Kim,Abu Hena Mostafa Kamal,Kwang-Hyun Shin,Myeong-Won Oh,Cheol-Soo Park,Young Keun Jung,Hwa-Young Heo,Chul-Won Lee,Beom Heon-Song,Sun-Hee Woo 한국작물학회 2010 한국작물학회 학술발표대회 논문집 Vol.2010 No.04

        The wild relative’s diploid species, which are reproductively isolated from one another, compromise populations with marked morphological variation, wide climatic tolerance, and adaptation to diverse habitats, and also vary genetically in biotic, abiotic stresses, and in seed protein content and quality. Large-scale proteomic analysis of three wild relatives of wheat grain (AA, BB, and DD genome) using matrix assisted laser desorption/ionization- time of flight (MALDI-TOF-MS), multi-dimensional protein identification technology (MudPIT), allowed the detection and classification of 213, 255 unique proteins (peptide match ≥ 2), which represents the most wide-ranging proteome exploitation to date. Development of standard proteomes exhibiting all of the proteins involved in normal physiology will facilitate the delineation of disease/defense (no. of unique protein (n) =33, 51), metabolism (n=15, 32), energy metabolism (n= 21, 27), protein synthesis (n=16, 22), folding/stability (n=17, 18), transcription (n=6, 18), cell growth/division (n=17, 17), signal transduction (n=16, 15), cellular organization (n=11, 12), development (n=9, 9), storage protein (n= 30, 7), transport facilitation (n=8, 6), and unclear classification (n= 14, 21), which is identification by using MALDI-TOF and LCQ DECA mass spectrometry couple to mascot database search, respectively. For instance, ABA inducible protein PHVA1 (HVA1), which can be induced by drought, cold, heat and salinity condition, and also basic endochitinase (RSCC, RSCA) showed defense against chitin containing fungal pathogens. Gluten (glutenin and gliadin), which is very important determinant for making high quality bread, noodles, and also associated with visco-elasticity. By using MALDI-TOF, we identified abundant disease related protein such as NBS-LRR involves in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack, puroindoline (a & b) and grain softness protein represents the molecular-genetic basis of grain texture. In addition, the PIN A and PIN B gene products have anti microbial properties with potential role in plant defense. Recent advances in mass spectrometry and bioinformatics have provided the means to characterize complex protein landscapes from a wide variety of organisms. Hierarchical clustering could be applied to protein information from different samples using Gene Pattern and NCSS software. Here we report also genome specific protein interaction network using Cytoscape software, which provides further insight into the molecular mechanism of biochemical pathways. By integrating shotgun proteomics with statistical and computation alanalyses, we developed promising understand about expressed protein and protein functions. Our approach should be applicable for marker assisted breeding or genetransfer for quality and stress research of cultivated wheat.

      • A correlation between pelvic node metastasis and clinical symptoms in the patient underwent staging surgery for the early-stage cervical cancer

        ( Ki Jin Ryu ),( Ye Won Chung ),( Hyo Sook Bae ),( Jae Kwan Lee ),( Nak Woo Lee ),( Tak Kim ),( Jae Yun Song ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-

        This study was conducted to evaluate the clinical factors which can expect pelvic nodal metastasis in patients with early-stage invasive cervical cancer, when nodal involvement had not been detected by pretherapeutic CT, MRI, with or without PET-CT. The medical records of 233 early-stage cervical cancer patients who had undergone staging surgery between November 1990 and February 2012 were reviewed. The incidence of histologically proved nodal metastasis was compared with the clinical factors that include age, BMI, initial symptom, clinical stage, histology, serum SCC and CEA, and postoperative complications. Statistical analysis was performed using SPSS program. Out of a total of 233 patients, nodal involvement was detected in 31(13.3%) by pathological examination. 65(28%) patients were asymptomatic, and among the 168(72%) symptomatic patients, vaginal bleeding and/or discharge was evident in 153(65%), and lower abdominal pain in 15(6%). The node-involved group showed higher rate of presenting lower abdominal pain as the initial symptom (p-value = 0.034). Clinical stage was statistically relevant to nodal involvement, but not to a type of clinical symptom. Neither the histology, age, BMI, tumor markers were, the postoperative complications (lymphedema, lymphocele) were not statistically related to pelvic nodal involvement. There was significant correlation between the histological nodal metastasis and the presentation of lower abdominal pain as initial symptom in early-stage cervical cancer patients. Although the reliability and pathophysiology of this finding are certainly need to be investigated by further studies, it might be worthwhile to consider a more active surgical lymph node dissection for management of patient with lower abdominal pain rather than vaginal bleeding or no symptom.

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