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So-Yoon Yee,Na-Yeon Kim,Ju-Yeon Park,Hye-Won Mok,Yu-Gyeong Kim,Bo-Young Seok,Hee-Jeong Hwang,Myong-Soo Chung 한국산업식품공학회 2018 학술대회 및 심포지엄 Vol.2018 No.04
Black pepper (piper nigrium L.) is a spice commonly used but has a problem with microbial control, so it needs non-thermal decontamination method for product quality of dried foods. Intense pulsed light (IPL) technology is a non-thermal method for superficial decontamination of foods to inactivate pathogenic microorganisms by using high peak power and short duration pulses of a broad-spectrum (170-2600 nm) using a xenon lamp. The objective of this study was to reduce total number of bacteria in ground black pepper effectively by combined treatments of IPL and immobilized TiO2 photocatalyst. Self-designed cyclone type of pilot-scaled IPL device (> 5 kg/h) was used, which makes samples to flow cyclonically in a vacuum space longer time rather than moving vertically. Using this device alone, without TiO2 coated, 0.3-0.6 log reductions were achieved under a total energy fluence of 14.85 J/cm2 (DC voltage; 1200, 1800, and 2400 V, pulse duty; 0.5, 2.1, and 3.0 ms, treatment time; 60, 120, 180, 240, and 300 s, frequency; 2 Hz). Subsequently, TiO2-coated quartz plates with different layers between light source and samples were installed to observe the effect of photocatalyst and the efficiency of decontamination was improved slightly. However to increase the effect of the photocatalyst, several factors (TiO2 particle size, TiO2 film thickness and transparency, adhesiveness between quartz and photocatalyst, etc.) need to be concerned additionally. Nevertheless, the application of IPL treatment combined with TiO2 photocatalyst offers a potential of effective non-thermal decontamination method for dealing with powder foods in food industry.
Factors associated with performance of infection control among some physical therapists
( Yoon-yee Seol ),( Mi Ah Han ),( Jong Park ),( So Yeon Ryu ) 대한물리치료학회 2016 대한물리치료학회지 Vol.28 No.2
Purpose: Infection management is important for physical therapists in order to protect patients and themselves since they often provide patient care and have physical contact with patients. This study examined the performance of infection control and associated factors among physical therapists. Methods: The study subjects were 174 physical therapists working in the G metropolitan city. The performance of infection control according to general characteristics, job-related characteristics, and infection-related characteristics were compared using t-test and ANOVA. Associations between awareness and performance of infection control were tested by correlation. Finally, multiple linear regression analyses were performed to examine the factors associated with performance of infection control. Results: Overall performance scores for personal and therapy room were 87.47±11.70 and 70.08±13.68, respectively. Both personal and therapy room infection control were lower for the degree of performance than the degree of awareness. In multiple linear regression analysis, the degree of performance at a personal level was related to current smoking status, type of charge therapy, supply of protection equipment, and awareness of personal infection control. The degree of performance of therapy room was related to injury experience in the workplace, supply of protection equipment, and awareness of therapy room infection control. Conclusion: Performance of therapy room infection control was lower than that of personal infection control. The performance was associated with the supply of protection equipment and awareness. Therefore, the degree of performance for infection control will be increased with proper supply of protection equipment in the hospital and increase the degree of awareness with adequate prevention edu-cation.
Factors associated with performance of infection control among some physical therapists
Seol, Yoon-Yee,Han, Mi Ah,Park, Jong,Ryu, So Yeon 대한물리치료학회 2016 대한물리치료학회지 Vol.28 No.2
Purpose: Infection management is important for physical therapists in order to protect patients and themselves since they often provide patient care and have physical contact with patients. This study examined the performance of infection control and associated factors among physical therapists. Methods: The study subjects were 174 physical therapists working in the G metropolitan city. The performance of infection control according to general characteristics, job-related characteristics, and infection-related characteristics were compared using t-test and ANOVA. Associations between awareness and performance of infection control were tested by correlation. Finally, multiple linear regression analyses were performed to examine the factors associated with performance of infection control. Results: Overall performance scores for personal and therapy room were $87.47{\pm}11.70$ and $70.08{\pm}13.68$, respectively. Both personal and therapy room infection control were lower for the degree of performance than the degree of awareness. In multiple linear regression analysis, the degree of performance at a personal level was related to current smoking status, type of charge therapy, supply of protection equipment, and awareness of personal infection control. The degree of performance of therapy room was related to injury experience in the workplace, supply of protection equipment, and awareness of therapy room infection control. Conclusion: Performance of therapy room infection control was lower than that of personal infection control. The performance was associated with the supply of protection equipment and awareness. Therefore, the degree of performance for infection control will be increased with proper supply of protection equipment in the hospital and increase the degree of awareness with adequate prevention education.
감염 ; 폐외 결핵 진단에서 2개의 전혈 인터페론 감마 측정법의 유용성 비교
한송이 ( Song Yee Han ),이혁 ( Hyuck Lee ),정동식 ( Dong Sik Jung ),김경희 ( Kyeong Hee Kim ),우수미 ( Su Mi Woo ),박소영 ( So Young Park ),서정민 ( Jeong Min Seo ),정진규 ( Jin Kyu Jung ),윤늘봄 ( Neul Bom Yoon ),이성우 ( Sung W 대한내과학회 2011 대한내과학회지 Vol.81 No.4
목적: QuantiFERON-TB GOLD (QFT-G)와 QuantiFERON-TB GOLD in tube (QFT-IT) 검사는 주로 활동성 폐결핵 또는 잠복결핵의 진단과 관련되어 연구되어져 왔으나, 폐외 결핵의 진단과 유용성은 아직 잘 밝혀지지 않은 상태이다. 본 연구는 폐외 결핵 환자에서 QFT-G와 QFT-IT의 진단적 유용성에 대해 비교 분석하였다. 방법: 2007년 6월부터 2010년 8월까지 임상적으로 폐외결핵이 의심되어 QFT-G, QFT-IT 검사를 한 환자 각각 56명과 48명을 대상으로 하였다. QFT-G와 QFT-IT의 민감도, 특이도, 양성예측도, 음성예측도와 QFT-IT의 cut-off value를 통하여 진단적 유용성을 분석하였다. 결과: 폐외 결핵으로 진단된 환자는 55명(53%)이었고 QFT-IT의 민감도, 특이도, 양성예측도, 음성예측도는 96%, 42%, 62%, 91%이었으며, QFT-G는 81%, 52%, 68%, 68%이었다. 감염부위에 따른 검사 결과 또한 민감도, 음성예측도에서 QFT-IT가 QFT-G보다 더 높은 결과를 보였다. 본 연구에서 cut-off value는 기존에 권고하고 있는 cut-off value의 범위 안에 포함되었다(0.30-0.45 IU/mL, sensitivity 95.8%, specificity 41.7%). 결론: QFT-IT는 M.tuberculosis 감염의 진단에 있어서 QFT-G보다 높은 민감도와 음성예측도를 보이며, 특이도에 있어서는 유사한 결과를 보여 새로운 IGRA방법으로서 폐외결핵의 진단을 더 강화시킬 수 있는 가능성을 보여주었다. Background/Aims: The QuantiFERON-TB Gold (QFT-G) and QuantiFERON-TB Gold in tube (QFT-IT) assays have been studied primarily for the use of diagnosing active pulmonary tuberculosis (TB) or latent TB. The clinical usefulness of these assays for the detection of active extrapulmonary (EP) TB has not been fully defined. The aim of this study was to compare the diagnostic value of these two interferon-gamma assays for EP-TB. Methods: From June 2007 to August 2010, we evaluated the usefulness of QFT-G (n=56) and QFT-IT (n=48) in patients (n=104) with suspected EP-TB. The diagnostic sensitivity, specificity, postive predictive value (PPV), and negative predictive value (NPV) of QFT-G and QFT-IT, and the cut-off value of QFT-IT were analyzed. Results: EP-TB was diagnosed in 55 (53%) patients. The overall sensitivity, specificity, PPV, and NPV of the QFT-IT assay were 96%, 42%, 62%, and 91%, respectively, and those of the QFT-G test were 81%, 52%, 68%, and 68%, respectively. In subgroup analyses according to infection site, the sensitivity and NPV of QFT-IT were higher than those of QFT-G. Analysis confirmed that the manufacturer`s recommended test cut-off value fell within our cut-off value range (0.30-0.45 IU/mL; 95.8% sensitivity, 41.7% specificity). Conclusions: The QFT-IT assay showed superior sensitivity and NPV, and equivalent specificity, as comparison with the QFT-G test for the detection of Mycobacterium tuberculosis infection. The logistic benefits of the QFT-IT test format should facilitate the diagnosis of EP-TB. (Korean J Med 2011;81:478-486)
증례 : 류마티스 ; 류마티스관절염 환자에서 발생한 비정형 대퇴골 골절의 1예
김담 ( Dam Kim ),정소담 ( So Dam Jung ),손창남 ( Chang Nam Son ),최지영 ( Ji Young Choi ),이승훈 ( Seung Hun Lee ),김이석 ( Yee Suk Kim ),성윤경 ( Yoon Kyoung Sung ) 대한내과학회 2014 대한내과학회지 Vol.87 No.2
류마티스관절염 환자에서 질환 자체의 활성도나 질환으로 인한 비스포스포네이트의 장기간 사용 및 PPI, 스테로이드의 사용으로 비정형 대퇴골 골절의 위험도가 높아질 수있으므로 비정형 대퇴골 골절에 대한 많은 연구가 필요하다고 생각하며 대퇴부 통증이 있는 경우 비정형 대퇴골 골절을 염두에 두고 면밀한 진찰과 영상진단을 해야 한다. Atypical femoral fractures are characterized by a subtrochanteric or diaphyseal location. Recent studies have suggested that long-term treatment with bisphosphonates might be associated with the occurrence of atypical femoral fractures. The present report describes a case involving a 60-year-old woman with left buttock pain that was unassociated with trauma. Her hip pain was initially considered to be a symptom of her underlying rheumatoid arthritis, but a plain radiography, bone scintigraphy, and magnetic resonance imaging revealed an insufficiency fracture in the lateral shaft of the left proximal femur. She had been treated with a bisphosphonate for 4.5 years because of a previous vertebral fracture. Her chronic, long-term rheumatoid arthritis and history of bisphosphonate administration were considered to be associated with the development of her atypical femoral fracture. (Korean J Med 2014;87:240-244)
일개 부산지역 3차 병원에서 관찰한 다제내성 결핵의 실태, 2005~2009
윤늘봄 ( Neul Bom Yoon ),이성우 ( Sung Woo Lee ),박수민 ( Su Min Park ),정일환 ( Il Hwan Jeong ),박소영 ( So Young Park ),한송이 ( Song Yee Han ),이유림 ( Yu Rim Lee ),정진규 ( Jin Kyu Jung ),김준모 ( Joon Mo Kim ),김수영 ( Su You 대한결핵 및 호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.71 No.2
Background: Although the prevalence of pulmonary tuberculosis has progressively decreased all over the world, drug-resistant tuberculosis is major obstacle in treating tuberculosis. This study was performed to examine the current prevalence and risk factors of drug resistant tuberculosis in a single tertiary hospital in Busan, Korea. Methods: We enrolled 367 patients with active pulmonary tuberculosis on a retrospective basis who had undergone mycobacterium culture and drug sensitivity tests between January 2005 and December 2009. We analyzed all clinical and radiographic parameters to find predictors related to drug resistant tuberculosis. Results: At least one incident of drug resistance was found in 75 (20.4%) patients. Isoniazid (18.8%) was the most frequent resistant drug, followed by rifampin (10.9%), ethambutol (7.1%), streptomycin (4.9%), and fluoroquinolone (2.7%). Resistance to second-line drugs was found in 37 (10.1%) patients. Multidrug resistance and extensively drug resistance was evident in 39 (10.6%) and 4 (1.1%) patients, respectively. Using multiple logistic regression analysis, history of previous treatment including relapse (odd ratio [OR], 11.3; 95% confidence interval [CI], 4.92~ 26.08; p<0.01), treatment failure (OR, 24.1; 95% CI, 5.65~102.79; p<0.01) and an age of below 46 years-old (OR, 3.8; 95% CI, 1.62~8.65; p<0.01) were found to be independent predictors of multidrug resistant tuberculosis. Conclusion: We found that the prevalence of drug resistant tuberculosis was considerably high. A careful consideration for possible drug resistant tuberculosis is warranted in patients with a history of previous treatment or for younger patients.