http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
손창남 ( Chang-nam Son ),김상현 ( Sang-hyon Kim ) 대한내과학회 2021 대한내과학회지 Vol.96 No.4
Anti-nuclear antibodies (ANAs) are autoantibodies against nuclear substances or other cellular components. ANA tests are used in the diagnostic process to screen patients with suspected rheumatic or autoimmune diseases. ANA-associated diseases are characterized by a high titer of antinuclear antibodies and include systemic lupus erythematosus, systemic sclerosis, and mixed connective tissue diseases. ANA test results must be cautiously interpreted as they can be positive not only in infections and oncological diseases but also for the healthy general population. The ANA test mainly uses the indirect immunofluorescence test, and the results are expressed in terms of the final titer and pattern. The ANA test can increase diagnostic value when used in conjunction with the evaluation of disease-related clinical symptoms. (Korean J Med 2021;96:337-340)
다양한 약제에 의해 급성 췌장염이 발생한 궤양성 대장염 환자
손창남 ( Chang Nam Son ),이항락 ( Hang Lak Lee ),주용원 ( Yong Won Joo ),이오영 ( Oh Young Lee ),한동수 ( Dong Soo Han ),윤병철 ( Byung Chul Yoon ),최호순 ( Ho Soon Choi ),함준수 ( Joon Soo Hahm ) 대한소화기학회 2008 대한소화기학회지 Vol.52 No.3
Acute pancreatitis is a serious disease with fatality rate up to 15%. We recently experienced a case of acute pancreatitis induced by multiple drugs in a patient with ulcerative colitis. A 20-year-old female visited with abdominal pain and hematochezia and diagnosed of ulcerative colitis. Sulfasalazine and prednisolone were used. However, acute pancreatitis occurred after 4 weeks of treatment with additional azathioprine treatment. Drug-induced pancreatitis was suspected, and she was recovered with conventional therapy for acute pancreatitis. Therefore, it was proposed that acute pancreatitis was induced by azathioprine. However, after the administration of sulfasalazine, pancreatitis relapsed. Furthermore, even the re-administration of 5-ASA and azathioprine induced relapse of acute pancreatitis. We concluded that acute pancreatitis was induced by multiple drugs in this patient with ulcerative colitis. (Korean J Gastroenterol 2008;52:192-195)
일차성 부갑상선 기능항진증으로 인한 칼슘피로인산 결정침착 질환
손창남 ( Chang Nam Son ),이지영 ( I Young Lee ),김담 ( Dam Kim ),주경빈 ( Kyung Bin Joo ),이승훈 ( Seunghun Lee ),송영수 ( Young Soo Song ),김동선 ( Dong Sun Kim ),태경 ( Kyung Tae ),유태석 ( Tae Seok Yoo ),전재범 ( Jae Bum Jun 대한류마티스학회 2014 대한류마티스학회지 Vol.21 No.2
Calcium pyrophosphate dihydrate (CPPD) deposition disease is a heterogeneous group of diseases with CPPD crystal deposition. Aging is the most common risk factor for CPPD deposition, followed by osteoarthritis and previous injury. Occasionally, CPPD depositions are associated with familial predisposition and metabolic diseases, including hemochromatosis, primary hyperparathyroidism, hypophosphatasia, and hypomagnesemia. CPPD deposition diseases associated with primary hyperparathyroidism in Koreans have rarely been reported. Thus, we report a case of a relatively young female patient with CPPD deposition disease associated with primary hyperparathyroidism, which was diagnosed through a polarized microscopic examination of the synovial fluid and a subtotal parathyroidectomy.
정전비용 고려한 PV시스템의 배전계통 연계 우선순위 결정에 관한 연구
손창남(Chang-Nam Son),한운동(Woon-Dong Han),문종필(Jong-Fil Moon) 대한전기학회 2014 전기학회논문지 P Vol.63 No.3
In this paper, when photovoltaic systems are connected to distribution system, most effective capacity and location of PV system are studied considering customer interruption costs of power distribution system. The reliability model of PV system considering the duration of sunshine, the model of time-varying load and Roy Billinton test system (bus2 model) are used. To simulate the effects of PV system, various cases are selected; (1) base case which is no connection of PV system to power distribution system when faults are occurred, (2) 3MW case which is 3[MW] connection of PV system (3) 4[MW] case, and (4) 20[MW] case which is 20[MW] connection of PV system to the bus of power distribution system. The capacity limit of connected PV system is settled to 14[MW] for all cases except case 4. The reliability and customer interruption costs for residential, general, industrial, and educational customer is evaluated.
손창남 ( Chang-nam Son ),김상현 ( Sang-hyon Kim ) 대한내과학회 2020 대한내과학회지 Vol.95 No.3
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease that affects various organs. SLE patients have an increased risk of infection compared to the general population. Immunosuppressive agents commonly used in SLE increase the risk of infection. Vaccination is a good way to reduce the risk of infection. However, some SLE patients are concerned that vaccination may worsen lupus disease activity or cause side effects. The latest SLE patient vaccination data were reviewed in this study, which focused on the safety, immunogenicity, and efficacy of influenza, pneumococcal, tetanus, hepatitis A, herpes zoster, and human papillomavirus vaccines. Korean immunization recommendations were also compared to those of other countries. (Korean J Med 2020;95:170-175)
주용원 ( Yong Won Joo ),손창남 ( Chang Nam Son ),정경희 ( Kyong Hee Jung ),박혜정 ( Hae Jeong Park ),김상헌 ( Sang Heon Kim ),김태형 ( Tae Hyung Kim ),손장원 ( Jang Won Sohn ),윤호주 ( Ho Joo Yoon ),최요원 ( Yo Won Choi ),정원상 ( 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.65 No.3
A chronic expanding hematoma (CEH) in the thorax is a rare and specific condition of chronic empyema. CEHs in the thorax are often associated with tuberculosis and/or previous surgical procedures. While the incidental detection of a pleural mass and dyspnea are common clinical manifestations, a few cases present with hemoptysis. We encountered a case of CEH in the thorax. This case is unique in that it developed without a prior history of tuberculosis or surgery and presented with massive hemoptysis accompanied by bronchopleural fistula. We report the third case of CEH in the thorax in Korea with a summary of the clinical characteristics of previous cases. (Tuberc Respir Dis 2008;65:216-221)
강직성 척추염 환자에서 발생한 경추부 장경근의 석회화 건염
윤혜진 ( Hyae Jin Yoon ),손창남 ( Chang Nam Son ),이승훈 ( Seung Hun Lee ),주경빈 ( Kung Bin Joo ),김태환 ( Tae Hwan Kim ) 대한류마티스학회 2013 대한류마티스학회지 Vol.20 No.6
Retropharyngeal calcific tendinitis, also known as calcific tendinitis of the longus colli muscle, was first described by Hartley in 1964. It is caused by deposition of calcium hydroxyapatite crystals in the longus colli muscles from C1 to C3. Retropharyngeal calcific tendinitis is diagnosed radiologically by the detection of amorphous calcification and pre-vertebral soft tissue swelling. Twelve cases of retropharnygeal calcific tendinitis have been reported in the Korean literature, but no cases with ankylosing spondylitis. In this case, we report an unusual case of retropharyngeal calcific tendinitis with ankylosing spondylitis.
증례 : 류마티스 ; 류마티스관절염 환자에서 발생한 비정형 대퇴골 골절의 1예
김담 ( Dam Kim ),정소담 ( So Dam Jung ),손창남 ( Chang Nam Son ),최지영 ( Ji Young Choi ),이승훈 ( Seung Hun Lee ),김이석 ( Yee Suk Kim ),성윤경 ( Yoon Kyoung Sung ) 대한내과학회 2014 대한내과학회지 Vol.87 No.2
류마티스관절염 환자에서 질환 자체의 활성도나 질환으로 인한 비스포스포네이트의 장기간 사용 및 PPI, 스테로이드의 사용으로 비정형 대퇴골 골절의 위험도가 높아질 수있으므로 비정형 대퇴골 골절에 대한 많은 연구가 필요하다고 생각하며 대퇴부 통증이 있는 경우 비정형 대퇴골 골절을 염두에 두고 면밀한 진찰과 영상진단을 해야 한다. Atypical femoral fractures are characterized by a subtrochanteric or diaphyseal location. Recent studies have suggested that long-term treatment with bisphosphonates might be associated with the occurrence of atypical femoral fractures. The present report describes a case involving a 60-year-old woman with left buttock pain that was unassociated with trauma. Her hip pain was initially considered to be a symptom of her underlying rheumatoid arthritis, but a plain radiography, bone scintigraphy, and magnetic resonance imaging revealed an insufficiency fracture in the lateral shaft of the left proximal femur. She had been treated with a bisphosphonate for 4.5 years because of a previous vertebral fracture. Her chronic, long-term rheumatoid arthritis and history of bisphosphonate administration were considered to be associated with the development of her atypical femoral fracture. (Korean J Med 2014;87:240-244)
성인형 스틸병 환자의 골수소견과 골수에서의 TNF-α와 IL-18의 발현
정경희 ( Kyong Hee Jung ),김혜영 ( Hye Yong Kim ),손창남 ( Chang Nam Son ),김주형 ( Joo Hyung Kim ),김원준 ( Won Jun Kim ),이경아 ( Kyeong A Lee ),박호현 ( Ho Hyun Park ),이웅수 ( Woong Soo Lee ),유대현 ( Dae Hyun Yoo ) 대한류마티스학회 2009 대한류마티스학회지 Vol.16 No.2
Objective: Inflammatory cytokines may play important roles in the pathogenesis of adult onset Still`s disease. The enhanced expression of IL-18 was reported in the bone marrow of a Japanese systemic onset juvenile rheumatoid arthritis patient but not in the other organs. To date, there are very few studies relating the bone marrow and AOSD. This study examined the bone marrow findings as well as TNF-α and IL-18 expression in the bone marrow of AOSD patients. Methods: A retrospective study was performed on 15 AOSD patients who had undergone a bone marrow examination at a university hospital. The clinical and laboratory findings, as well as the bone marrow findings, were analyzed. Immunohistochemistry of IL-18 and TNF-α in bone marrow was performed. Results: The bone marrow cellularity and myeloid/erythroid cell ratio showed no correlation with the clinical and laboratory findings. TNF-α was expressed at 0.8∼9.8% and IL-18 was expressed at 0.4∼9.8% of bone marrow cells. Cytokine expression was not associated with the clinical patterns of AOSD. The platelet count correlated with the bone marrow TNF-α expression but TNF-α did not correlate with IL-18 expression. Conclusion: TNF-α and IL-18 expression in bone marrow were observed in some AOSD patients but there was no correlation with the other clinical and laboratory findings except for the platelet count.
증례 : 류마티스 ; 피부근염 환자에서 발생한 창자벽 공기 낭증 -증례보고와 문헌고찰-
유미연 ( Mi Yeon Yu ),이강록 ( Kang Lok Lee ),박재근 ( Jae Keun Park ),안가영 ( Ga Young Ahn ),손창남 ( Chang Nam Son ),조온구 ( On Koo Cho ),전재범 ( Jae Bum Jun ) 대한내과학회 2015 대한내과학회지 Vol.88 No.4
PCI는 피부근염에서 발생할 수 있는 드문 합병증으로 증례가 매우 적어 정확한 원인 및 위험인자에 대해 잘 알려지지 않았다. 본 증례 및 이전 논문의 증례를 토대로 볼 때 일반적으로 PCI에서의 위험 요소로 고려되는 코르티코스테로이드 및 면역 억제제를 피부근염에서의 PCI 위험인자로 단정하기는 어려울 것으로 보인다. 다만 전체 PCI 중 피부근염에서 발생하는 PCI가 여성에서 발병되는 비율이 높은 것으로 관찰되어 이를 위험인자로 고려할 수 있다. 피부근염 환자에서 발생하는 PCI를 조기에 진단하고 치료하여 환자의 생존율을 높일 수 있도록 이러한 성별 및 추가적인 위험인자에 대해 다기관 및 전향적인 연구가 시행되어야 할 것으로 생각된다. Pneumatosis cystoides intestinalis (PCI) is a rare disease with intramural gas formation in the gastrointestinal tract. The causes of PCI are various, and are commonly associated with collagen vascular disease. We present a case of a 48-year-old female with dermatomyositis (DM) who also developed PCI. Her risk of PCI may have been increased by multiple factors such as gender, DM itself, and medications including corticosteroids, methotrexate, and azathioprine. While the cause of, and risk factors for PCI in DM patients are not well known on a global scale, outcomes range from benign to life threatening. Therefore, we present a case study and review the literature to identify candidate risk factors for PCI.