CdS/Cu_2s異種接合의 製作 및 熱處理效果

金榮咸,李基善 동국대학교 재료과학연구소 1982 材料科學硏究所 論文集 Vol.2 No.-

眞空蒸着 및 浸淸方法에 의한 CdS/Cu_2S 太陽電池의 製作에 있어 carrier 포획층인 CdS薄膜 및 光吸收層인 Cu_2S層의 形成條件과 接合形成 후의 熱處理條件等을 調査하였다. CdS薄膜 蒸着時의 基板溫度는 180℃ 程度가 적당하였고, Cu_2S層의 형성은 PH 4의 CuCl 溶液에 약 5초간 浸淸하는 것이 最適이었다. Cu_2S層 形成後의 熱處理는 190℃의 溫度에서 10∼30分間 實施하는 것이 적당하였다. In fabricating the CdS/Cu_2S solar cells by vacuum evaporation and dipping method, the optimum conditions for forming CdS thin film as a carrier collection layer and Cu_2S layer as a light absorption layer, as well as the optimum heat treatment condition after formation of Cu_2S layer, have been investigated. The optimum substrate temperature was about 180℃ when depositing CdS thin film, and the best Cu_2S layer was obtained by dipping CdS thin films into CuCl solution of PH 4 for about 5 seconds. Also the best results was obtained when the fabricated junction was heat treated at 190℃ for 10∼30 minutes.

Inhibitory Effect of Cordycepin on Human Platelet Aggregation

박화진,--,--,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.1

Cordycepin separated from Cordyceps militaris is a major physiologic active component in Cordyceps militaris. The platelet aggregation is stimulated by Ca^(2+), which is either mobilized from intracellular endoplasmic reticulum or transported from extracellular space. cGMP antagonizes the actions of Ca^(2+). Based on these facts, we have investigated the effects of cordycepin on the mobilization of Ca^(2+) and the production of cGMP on collagen (10 ㎍/ml)-induced human platelet aggregation. Cordycepin potently stimulated the human platelet aggregation induced by collagen (10 ㎍/ml) in a dose-dependent manner. Cordycepin (500 μM) inhibited also the collagen-induced human platelet aggregation in the presence both 1 mM and 2 mM of CaCl_(2). These are in accord with the results that cordycepin inhibited the Ca^(2+)-influx on collagen-induced human platelet aggregation. These results suggest that cordycepin decrease the intracellular Ca^(2+) concentration to inhibit collagen-induced human platelet aggregation. Besides, cordycepin increased the level of cGMP on collagen-induced human platelet aggregation. This result is related with the decrease of intracellular Ca^(2+) concentration, because cGMP inhibits the mobilization of Ca^(2+). In addition, cordycepin inhibited the human platelet aggregation induced by LY-83583, inhibitor of guanylate cyclase. This result suggested that cordycepin inhibit the platelet aggregation by stimulating the activity of guanylate cyclase. In conclusion, we demonstrated that cordycepin might have the antiplatelet function by inhibiting Ca^(2+)-mobilization via the stimulation of the production of cGMP.

Inhibitory Effect of Clavicepitaceae on Serotonin Release out of Human Platelets and Human Platelet Aggregation

박화진,--,--,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2004 Journal of biomedical laboratory sciences Vol.10 No.1

We have investigated the effects of hypha-water extracts (HWE), fruit body-water extracts (FWE) and cordycepin from Cordyceps militaris on serotonin release out of human platelets and human platelet aggregation. HWE and FWE inhibited the release of [^(3)H]-serotonin from human platelet stimulated by thrombin (2 U/ml) or collagen (20 ㎍/ml) in a dose-dependent manner. Furthermore, cordycepin, a major component of Cordyceps militaris, inhibited the human platelet aggregation induced by collagen (10 ㎍/ml) in a dose-dependent manner. These results suggest that cordycepin containing in HWE and FWE may inhibit the serotonin release by suppressing the collagen-induced human platelet aggregation. Accordingly, our data demonstrate that HWE and FWE containing much cordycepin might have antithrombotic and antimigrainous functions.

홍삼류의 섭취가 비만과 혈중 지질의 상호관계에 미치는 영향

박화진,이정희,이소진,함혜선,조현정,임창률,유영빈,박기현 대한의생명과학회 2000 Journal of biomedical laboratory sciences Vol.6 No.4

비만은 동맥경화의 위험인자로서 혈중에 triglyceride의 농도를 종가시키고, 상대적으로 HDL-Cholesterol의 농도를 감소시킴과 동시에 수축기 혈압을 상승시킨다. 본 연구에서 홍삼제품류를 4년 또는 5년 동안 복용해 온 건강한 사람 (ginseng군)과 홍삼제품을 복용하지 않은 건강한 사람 (control군)을 대상으로 하여 신체 계측치로부터 비만지수를 구하고 이것과 혈중의 triglyceride (TG)농도, TG/HDL-Cholesterol ratio 및 수축기 혈압과의 상호관계를 연구한 바, ginseng군에서는 대조군에 비해 혈중의 TG 농도가 일정하게 유지되었고, TG/HDL-Cholesterol ratio 및 수축기 혈압도 일정하게 유지되었다. 이러한 현상은 ginseng군에서 기호품으로 alcohol을 섭취하거나, 흡연을 한 경우에도 상관없이 일정하게 유지 되었다. 이 결과는 홍삼제품류를 장기 복용하면 비만의 저하 및 고혈압 또는 동맥경화의 위험인자가 억제될 수 있고, 결론적으로 비만, 고혈압 및 동맥경화를 예방할 수 있을 것으로 추정한다. Obesity is the risk fcactor of atherosclerosis and not only increases triglyceride concentration in blood but also decreases relatively the ratio of TG to HDL-Cholesterol in blood. In case of obesity, systolic blood pressure is also increased in responding the increase of TG in blood. Index of obesity in red ginseng-taking group (ginseng group) was lower as compared with non-red ginseng-taking group (control group). The TG concentration, the ratio of triglyceride to HDL-cholesterol in blood and systolic blood pressure were decreased in the subjects of ginseng group compared with that in control group. It is inferred that long-term intake of ginseng products may help to prevent the risk of atherosclerosis and obesity.

A Study on the Water-Hammering Type Power System of Yi Min-cheol’s Astronomical Clock

Seon Young Ham,Sang Hyuk Kim,Yong Sam Lee 한국천문학회 2017 天文學會報 Vol.42 No.2

A Study on the Operation Mechanism of Celestial Movement Apparatus of ChoiYuJi's Armillary Sphere(渾天儀)

Seon Young Ham,Sang Hyuk Kim,Yong Sam Lee 한국천문학회 2015 天文學會報 Vol.40 No.1

A Study on the Internal Composition for the Operating Mechanism of Heumgyeonggaknu(欽敬閣漏) -On the Internal Composition of Clepsydra and Jujeon(籌箭)-

Seon Young Ham,Sang Hyuk Kim,Yong-gi Kim,Yong Sam Lee 한국천문학회 2016 天文學會報 Vol.41 No.1

Litsenolide A2: The major anti-inflammatory activity compound in <i>Litsea japonica</i> fruit

Ham, Young-Min,Cho, Su-Hyeon,Song, Sang-Mok,Yoon, Seon-A,Lee, Yong-Bum,Kim, Chang-Sook,Kwon, Seung-Hae,Jeong, Myeong Seon,Yoon, Weon-Jong,Kim, Kil-Nam Elsevier 2017 Journal of Functional Foods Vol.39 No.-

<P><B>Abstract</B></P> <P>In this study, we investigated the anti-inflammatory effect of litsenolide A2 (LNA2) isolated from <I>L. japonica</I> fruit and its mechanism of action in LPS-induced RAW 264.7 cells. LPS-induced production of anti-inflammatory mediators and cytokines such as NO, PGE<SUB>2</SUB>, iNOS, COX-2, TNF-α, and IL-6 was significantly inhibited by LNA2. Next, western blot experiments were performed to investigate the mechanism of action of the anti-inflammatory effect of LNA2. The results indicated that LNA2 markedly reduced the LPS-induced activation of NF-κB and the nuclear translocation of NF-κB p65. Furthermore, LNA2 also inhibited the phosphorylation of MAPK by LPS. LNA2 was the major component in the ethanol extract of <I>L. japonica</I> at 59 mg/g according to high performance liquid chromatography (HPLC). These results indicate that LNA2 can be used as a functional and marker compound for standardization of the manufacturing process when <I>L. japonica</I> fruit is used as a functional food.</P> <P><B>Highlights</B></P> <P> <UL> <LI> We study the anti-inflammatory effect of LNA2 in LPS-activated RAW 264.7 cells. </LI> <LI> LNA2 inhibited production of pro-inflammatory mediator and cytokines. </LI> <LI> LNA2 exhibited anti-inflammatory properties by suppression of NF-κB and MPAKs. </LI> <LI> LNA2 was the major component in the ethanol extract of <I>L. japonica</I> at 59 mg/g. </LI> </UL> </P>

Network Analysis of the Symptoms of Depressive Disorders Over the Course of Therapy: Changes in Centrality Measures

Seon-Cheol Park,Yaeseul Kim,Kiwon Kim,Young Sup Woo,Jung-Bum Kim,Eun Young Jang,Hwa-Young Lee,Hyeon-Woo Yim,Byung-Joo Ham,Jae-Min Kim,Yong Chon Park 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.1

Objective Network analysis can be used in terms of a novel psychopathological approach for depressive syndrome. We aimed to estimate the successive network structures of depressive symptoms in patients with depressive disorder using data from the Clinical Research Center for Depression study. Methods We enrolled 1,152 South Korean adult patients with depressive disorders who were beginning treatment for first-onset or recurrent depressive episodes. We examined the network structure of the severities of the items on the Hamilton Depression Rating Scale (HAMD) at baseline and at weeks 2, 12, 25, and 52. The node strength centrality of all the HAMD items at baseline and at week 2, 12, 25, and 52 in terms of network analysis. Results In the severity networks, the anxiety (psychic) item was the most centrally situated in the initial period (baseline and week 2), while loss of weight was the most centrally situated item in the later period (weeks 25 and 52). In addition, the number of strong edges (i.e., edges representing strong correlations) increased in the late period compared to the initial period. Conclusion Our findings support a period-specific and symptom-focused therapeutic approach that can provide complementary information to the unidimensional total HAMD score.

Warming Therapy for Spinal Surgery Patients

Keun Young Ham,Hye Young Ahn,Hye Seon Choi 보안공학연구지원센터 2016 International Journal of Bio-Science and Bio-Techn Vol.8 No.5

This study has tested an infrared radiation surgical gown (IRSG) and a carbon nanofiber thermal pad (CNTP) to verify the potential of these new warming therapies for the prevention of hypothermia in spinal surgery patients. The study is a quasi-experimental study using the non-equivalent control group pretest-posttest design. The study period was from July 14 to November 30, 2014, and subjects were an IRSG group of 28 patients, a CNTP group of 30 patients and a control group of 28 patients who were admitted to E university hospital in D city to have spinal surgery. The collected data were analyzed using PASW Statistics 20.0. χ²-test and ANOVA were used to test homogeneity among the three groups, and ANCOVA was used to measure temperature changes and subjective thermal discomfort in order to verify the effectiveness of the experimental treatments. As a result, from 75 minutes after tube insert (F = 8.142, p = .001) to the time of its removal (F = 36.825, p<.001), esophageal temperatures in the IRSG group and the CNTP group were significantly higher than in the control group. The three groups had significantly high tympanic temperatures with the CNTP group showing the highest temperatures followed by the IRSG and the control group from the time of entering the recovery room (F = 42.820, p<.001) to 30 minutes after (F = 51.966, p<.001). Also the IRSG group and the CNTP group showed significantly low subjective thermal discomfort at 15 minutes after entering the recovery room (F = 6.737, p = .002). The study has confirmed that IRSG and CNTP applied to spinal surgery patients are effective in preventing hypothermia and reducing thermal discomfort during and after surgery. Warming therapy must be provided to patients undergoing spinal surgery under general anesthesia, and hopefully, IRSG and CNTP will be used as an independent nursing intervention.