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박용석,석종식,최덕영,임광세 대한신경외과학회 1984 Journal of Korean neurosurgical society Vol.13 No.2
We have recently experienced a case of ependymoblastoma arising in the posterior fossa. 8 years old Korean boy suffered from headache, vomiting, diplopia and ataxic gait since 4 months prior to admission revealed drowsy mental state papilledema of both eyes, left abducens nerve paralysis, mild cerebellar syndrome in the neurologic examination. The radiological findings of skull revealed increased intracranial pressure and brain CT scan showed calcified round high density mass in the posterior fossa. After 3 weeks of V-P shunt operation, relatively well demarcated grayish-pink mass between the vermis of cerebellum and right cerebellar hemisphere was removed. The histological finding had a pattern of solid cord aroused thin walled blood vessel and typical ependymal rosette. The patient died at 6th postoperative day due to brain stem swelling.
박용석,석종식,최덕영,임광세 대한신경외과학회 1984 Journal of Korean neurosurgical society Vol.13 No.3
The brain computerized tomography, an epoch-making diagnostic procedure has caused a revolutionary change in the neurosurgical field; the correct localization of small space occupying lesion wherever it is in the brain without pain and harm to the patients. The brain CT findings of 3035 patients which were examined in this hospital during past 29 months from Oct. 1981 to March 1984 were analysed and the literature review was made. The results of analysis are as follows: 1) 37.1% of total 3035 cases were observed abnormal, including 29% of head injured patients, 42.4% of non-trauma cases, 57.6% of emergency cases' and 15.2% of non-emergency cases, 2) The rates of abnormal findings were proportional to the degree of consciousness disturbance in the head injured patients and severity of the neurological deficits in the other neurosurgical patients. 3) The follow up studies were performed for 287 patients among 1127 patients having abnormal findings in the first check and we found the improving process of various lesion and the resolving process of hematoma after operation. The follow up studies were performed for 138 patients having normal findings in the first check and 26% of these cases were observed abnormal, including 21.5% of head injured cases and 55% of the non-trauma cases. 4) 94% of patients with spontaneous subarachnoid hemorrhage showed bleedings chiefly in the basal cistern.
박용석,이영배,서강원,최덕영,임광세 대한신경외과학회 1983 Journal of Korean neurosurgical society Vol.12 No.3
The pathological manifestation of the patient with convulsive seizures has not been clearly proved mostly until the clinical use of brain computerized tomography. The brain C.T. findings, anamnesis, clinical diagnosis in the 133 consecutive patients who admitted to this hospital because of convulsive seizures from Oct. 1981 to Feb. 1983 were analysed and literature review was made. 1) The C.T. scan revealed structural abnormalities in 46% of patients with seizure disorders, and their main clinical diagnosis were cerebral infarction or intracranial hematoma, cortical atrophy non-specific granuloma etc. 2) The older patients had a high rate of abnormal findings in the brain C.T. than younger patients. 3) The patients having short duration of disease history had higher rate of abnormal C.T. findings. 4) The patients with focal seizure had higher abnormal findings than generalized seizure. 5) The patients with seizure only showed C.T. abnormalities in 22% of cases inspite of patients with positive neurological findings showing C.T. abnormalities in 80% of cases. 6) The patients with temporal lobe lesion showed focal seizures usually in higher rate in compare with the patients with lesion in other part of brain.
실험적 척추손상에서 Naloxone이 Na^(+)K^(+)ATPase 활성도에 미치는 영향
박용석,서강원,임광세 대한신경외과학회 1985 Journal of Korean neurosurgical society Vol.14 No.2
The Na^(+) K^(+) ATPase activity, whose disturbance have been implicated in the pathophysiology of a variety of disease processes, have been shown to be reduced in traumatized spinal cord and in ischemic brain made by decapitation or carotid artery occlusion by many authors, but MacMillan contrary documented the increase of this ferment in ischemic rat brain, following the electrocautery of the bilateral vertebral arteries and carotid arteries. This experiment was intended to study the cause of the above two contradictory results and the effect of Naloxone to the Na^(+) K^(+) ATPase activity following experimental spinal cord injury. Thirty cats were divided to 3 groups : Control No. 1, control No. 2, and Naloxone groups. The Na^(+) K^(+) ATPase activity was measured by variation of Kang & Lee method and the experimental spinal cord injury was made by falling 20 gm. of iron bar from 20 cm height to exposed thoracic cord. 1) In control No. 1 group the the Na^(+) K^(+) ATPase activity increased 21.4 % after 30 minutes of trauma showing significant difference(p<0.05). 2) In control No. 2 group it increased 13.8% (p<0.01) after 5 minutes, 11.6% (p<0.05) after 30 minutes showing significant difference. 3) In Naloxone group (10 ㎎/㎏ was injected I.V. before 30 minutes of trauma)it did not show any significant change after 5 and 30 minutes of trauma. 4) Discussion was made upon above experimental results with literature review.
Solid-Phase Epitaxy Emitter for Silicon Solar Cells
Kim, Hyunho,Park, Sungeun,Ji, Kwang-Sun,Lee, Kyung Dong,Kim, Seongtak,Bae, Soohyun,Ahn, Seh-Won,Lee, Heon-Min,Kang, Yoonmook,Lee, Hae-Seok American Scientific Publishers 2016 Journal of nanoscience and nanotechnology Vol.16 No.10
<P>This paper presents a new emitter formation method, 'solid-phase epitaxy emitter,' that involves an applied solid-phase epitaxial growth based on the rapid thermal processing of a-Si:H thin films. We describe the solid-phase epitaxial growth of intrinsic and phosphorous-doped a-Si: H thin films through rapid thermal processing using radio-frequency plasma-enhanced chemical vapor deposition. The phase transition of these films results from heat treatment above 600 degrees C. We examined the defects in the epitaxially grown silicon that formed at the phase interfaces. Phosphorous-doped a-Si: H produced using phosphine gas (PH3, diluted H-2) exhibited a diminished crystallinity compared with intrinsic a-Si: H because of the disturbance of dopant atoms. Based on this formation method, we fabricated a solid-phase epitaxy emitter cell with an efficiency of 16.7%. In addition, this method is expected to be simpler and more cost effective than the conventional method.</P>
Glucose Transporter-1 Expression in Squamous Cell Carcinoma of the Tongue
최윤석,Seok Jin Kim,Dae Sik Kim,Seh Jong Park,Yong Park,Hye Jin Shin,Kwang-Yoon Jung,Seung-Kuk Baek,Bong Kyung Shin,Jung Woo Choi,Byung Soo Kim,Sang Won Shin,Yeul Hong Kim,Jun Suk Kim 대한암학회 2007 Cancer Research and Treatment Vol.39 No.3
Purpose: Tumor cells are known to express hypoxia-related proteins such as glucose transporter-1 (Glut-1). These hypoxia-induced changes may allow tumor cells to survive under sustained hypoxic microenvironments, and the surviving tumor cell under hypoxia may develop a more aggressive phenotype and so result in a poor prognosis. Materials and Methods: The Glut-1 expression was analyzed by immunohistochemistry, and its association with the prognosis was assessed in 60 patients with squamous cell carcinoma of the tongue.Results: The Glut-1 expression was diffuse with a membranous pattern, and the median percentage of Glut-1 positive tumor cells was 60% (range: 0.0∼90.0%). A high Glut-1 expression (the percentage of positive tumor cells ≥ the median value, 60%) was associated with the location of primary lesion, lymph node metastasis status and disease stage (p〈0.05).Theexpression of Glut-1 was correlated with the Ki-67 expression (r=0.406, p=0.001). Microvessel density, as represented by CD31 staining, was also correlated with the Glut-1 expression although its significance is weak (r=0.267, p=0.039). On the univariate analysis, the group with a high Glut-1 expression showed poorer overall survival than the group with a low Glut-1 expression (p〈0.05). However, the Glut-1 expression failed to show any independent prognostic significance on the multivariate analysis.Conclusion: The expression of Glut-1 may be useful for predicting the prognosis and determining the treatment strategy for the management of squamous cell carcinoma of the tongue. (Cancer Res Treat. 2007;39:109-115)