반복치료로 호전된 호산구성 폐렴 유사 폐흡충증 1예

박세진,김희규,김봉준,이천우,옥철호,정만홍 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

우리나라에서 인기 있는 게장등의 섭취로2) 성인뿐만 아니라 소아에서도 지속적으로 보고되고 있는 폐흡충증은 다양한 임상양상을 보일 수 있다. 저자들은 방사선 소견상 만성 호산구성 폐렴과 유사하였고, 반복적인 치료로 호전된 폐흡충증 1예를 경험하였기에 보고하는 바이다. Paragonimiasis mostly occurs by ingestion of raw or undercooked freshwater crabs or crayfish. Recently, re-emergence of paragonimiasis is reported because of ingestion of raw food such as freshwater fish and Gejang (marinated raw crabs). As the radiological features as well as the laboratory findings are similar to those of chronic eosinophilic pneumonia, the diagnosis of pulmonary paragonimiasis is often difficult and delayed. A 43 year-old female was visited our hospital for migrating and new developing consolidative lung lesions and peripheral blood eosinophilia. The eosinophil profile of leukocyte was 32% (absolute count 2,690 /mm3). Histologic finding was organizing pneumonia pattern with severe infiltration of eosinophils. Parasite specific antibody IgG forParagonimus westermani was positive (titer:0.61, normal range<0.20). After treatment with praziquantel (75mg/Kg once a day for 2days), the chest x-ray was clearly resolved. Follow-up study showed right pleural effusion, newly developed focal infiltration, and several nodules. After retreatment, we couldn't find any recurrent evidence.

대학 스포츠 종목별 우수선수들의 신체조성에 관한 연구 : 第1報-種目別 身體組成 測定 結果

성동진,오세진,최태석,송홍선 韓國體育大學校附屬 體育科學硏究所 1997 韓國體育大學校附屬 體育科學硏究所論文集 Vol.16 No.1

The purpose of this study was to investigate the characteristics of Body composition for K University elite Athletes. The total subjects were 458 athletes(331 male athletes, 127 female athletes). The results was as fellowing 1. Average triceps thickness, male was 9.59mm and female was 20.20mm. 2. Average subscapula thickness, male was 11.17mm and female was 14.08mm. 3. Average %Fat, male was 14.05% and female was 23.57%. 4. Average fat mass, male was 10.43kg and female was 14.17kg. 5. Average Lean body mass, male was 61.7kg and female was 44.84kg.

Determination of the Harvest Date and Ripening Phase of ‘Seolhyang’ Strawberry

Sae Jin Hong(홍세진),Hyang Lan Eum(엄향란) (사)한국생물환경조절학회 2020 시설원예‧식물공장 Vol.29 No.1

본 연구는 ‘설향’ 딸기의 수확시기에 따른 품질 특성을 확인하고, 상온(20°C )・cold-chain(10-12°C)・저온(5°C) 유통에 적합한 숙성단계를 조사하기 위하여 수행하였다. 딸기는 12월 20일부터 5월 9일까지 6번에 걸쳐서 수확하였다. 딸기를 수확할 때 적합한 숙성 정도는 3월까지는 경도 2.9-3.0 N, 당도 8.6 °Brix 이상이었으나, 4월 이후에는 당도가 감소하였다. 딸기의 숙성을 결정하는 주요 요인은 붉게 착색된 정도이고, Hunter a 값은 32-37, hue angle은 36-45°였다. 딸기의 후숙 실험에서 숙성 정도는 딸기의 착색이 진행되는 정도에 따라서 결정되었으며, 상온에서는 10%/day, 10-12°C에서는 5%/day, 5°C에서는 3%/day씩 착색이 진행되었다. 따라서 상온에서 유통할 경우에는 80%, cold-chain ・ 저온에서 유통하기 위해서는 90%의 착색된 과실을 수확하여야 유통하는 동안 상품성이 유지되었다. 그리고 상온에서는 70% 이하로 착색된 딸기를 유통하거나, 저온에서는 80% 이하로 착색된 딸기를 유통하는 경우에는 100% 착색이 이루어지지 않고 상품성을 잃었다. The purpose of this study was to investigate the quality characteristics of ripe fruit based on harvest date and to examine the ripening phase of ‘Seolhyang’ strawberry suitable for room temperature, cold-chain, and low temperature distribution. The strawberries were harvested six times between December 20 to May 9. The appropriate maturity of strawberries is characterized by the firmness of approximately 2.9–3.0 N, and SSC remained above 8.6 °Brix until March and declined after April. The quality index values that determine the maturity stage of strawberries should be red color, Hunter a value ranging from 32 to 37, and hue angle of 36-45°. For the after-ripening experiment, the progression rate of the ripening stage determined based on strawberry color was 10%/day at room temperature, 5%/day at 10-12°C, and 3%/day at 5°C. Thus, strawberries should be harvested at 80% coloring stage for distribution at room temperature and at least 90% for low temperature storage to maintain the merchantability. Besides, strawberries harvested at 70% coloring stage at room temperature and strawberries harvested below 80% coloring stage at low temperatures below 5°C had lost commercial value before reaching 100% coloring stage.

Differentiation between mucus secretion and endoluminal tumors in the airway: analysis and comparison of CT findings.

Hong, Sae Rom,Lee, Yeo Jin,Hong, Yoo Jin,Hur, Jin,Kim, Young Jin,Choi, Byoung Wook,Lee, Hye-Jeong American Roentgen Ray Society 2014 American Journal of Roentgenology Vol.202 No.5

<P>The objective of our study was to suggest CT features that help differentiate transient mucus secretion from airway tumors in the evaluation of soft-tissue nodular lesions confined within the airway lumen.</P>

FC 1-2 : Immunomodulatory effects of Ul-Jin thermomineral water on Oxazolone-induced atopic dermatitis murine model

( Sae Mi Park ),( Dae Hong Kim ),( Eun Jong Song ),( Kum Hee Jung ),( Jun Young Lee ),( Young Bok Lee ),( Dong Soo Yu ),( Jin Wou Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Background: Althoug the therapeutic effect of Balneotherapy for atopic dermatitis is controversial, many atopic patients are visiting thermomineral springs and present clinical improvements. Objectives: The aim of this study is to evaluate the therapeutic effect and the immunologic mechanism of balneotherapy in atopic dermatitis. Methods: Oxazolone-induced atopic dermatitis murine model was used for evaluating the therapeutic effect of balneotherapy with Ul-Jin thermomineral water. Confocal microscopic imaging analysis was performed for lesional expression of IL-4, IL-17, CD4, Foxp3, and TNF-a. Lesional mRNA expression of IL-33, TSLP, and Foxp3 was evaluated by real-time reverse transcriptase polymerase chain reaction method. Histologic evaluation was also performed. Results: Comparing with distilled water balneotherapy group, the lesional expression of IL-4, TNF-a, IL-17 was decreased in mineral water balneotherapy group by confocal microscopic examination. However, Confocal microscopic evaluation of CD4 and Foxp3 showed increase in mineral water balneotherapy. The lesional mRNA levels of IL-33 and TSLP showed reduction in mineral water balneotherapy group, whereas the level of mRNA of Foxp3 increased in mineral water balneotherapy group. Conclusion: These results suggest that balneotherapy can be an effective and safe treatment option in atopic dermatitis.

Effect of Korean Herbal Formula (Modified Ojayeonjonghwan) on Androgen Receptor Expression in an Aging Rat Model of Late Onset Hypogonadism

Sae Woong Choi,Seung Hwan Jeon,Eun Bi Kwon,Guan Qun Zhu,Kyu Won Lee,Jin Bong Choi,Hyun Cheol Jeong,Kang Sup Kim,Sang Rak Bae,Woong Jin Bae,Su Jin Kim,Hyuk Jin Cho,U-Syn Ha,Sung Hoo Hong,Sung Yeoun Hwa 대한남성과학회 2019 The World Journal of Men's Health Vol.37 No.1

Purpose: Testosterone replacement therapy is an effective treatment for late-onset hypogonadism (LOH) despite a few con-traindications and side-effects. The aim of this study was to determine whether modified Ojayeonjonghwan (KH-204, Korean herbal formula) improved LOH. KH-204 is a strong antioxidant herbal formula. We evaluated the effect of Korean herbal pre-scription on androgen receptor (AR) expression in an aged rat model of LOH. Materials and Methods: Eighteen-month-old rats were used as aged LOH rat models. Eighteen Sprague-Dawley rats were ran-domly divided into three equal groups of six animals each and treated with one of the following: 1) normal control group (oral administration with distilled water, n=6), 2) KH-204 200 group (oral administration with 200 mg/kg of KH-204, n=6), and 3) KH-204 400 group (oral administration with 400 mg/kg of KH-204, n=6). After four weeks of treatment (once daily, distilled water or KH-204), serum testosterone levels, changes in testicular and epididymal weight, Western blotting analysis of AR ex-pression and measurement of oxidative stress were examined. Results: Treatment with the herbal formulation KH-204 200 mg/kg and 400 mg/kg (1) increased the weights of testis and epi-didymis; (2) increased the level of serum testosterone; (3) increased the level of superoxide dismutase and reduced the level of 8-hydroxy-20-deoxyguanosine; and (4) upregulated AR expression in testicular tissue. Conclusions: KH-204 might be an effective alternative for LOH. It improves antioxidant mechanisms and increases testicular AR expression without side-effects.

Predictive factors for treatment response using dual-energy computed tomography in patients with advanced lung adenocarcinoma

Hong, Sae Rom,Hur, Jin,Moon, Yong Wha,Han, Kyunghwa,Chang, Suyon,Kim, Jin Young,Im, Dong Jin,Suh, Young Joo,Hong, Yoo Jin,Lee, Hye-Jeong,Kim, Young Jin,Choi, Byoung Wook Elsevier 2018 European journal of radiology Vol.101 No.-

<P>Conclusions: Dual-energy CT using a quantitative analytic method based on iodine concentration measurements can be used to predict the effects of chemotherapy in patients with advanced adenocarcinoma.</P>

질소 시비량이 봄배추의 저장 품질과 깨씨무늬장해 발생에 미치는 영향

홍세진(Sae Jin Hong),김병섭(Byung-Sup Kim),박남일(Nam Il Park),엄향란(Hyang Lan Eum) 한국원예학회 2017 원예과학기술지 Vol.35 No.6

본 연구는 재배 중 질소 시비량이 봄배추 ‘력광’과 ‘청옥’의 깨씨무늬장해 발생 및 저장성에 미치는 영향을 구명하고자 수행되었다. 배추재배 시 질소 1/2 시비, 기준 시비, 2배 시비(24, 48, 96kg/10a)로 처리하였다. 저장 중 품질 변화는 가용성당(glucose, fructose) 함량, 색도(Hunter L, a, b), 깨씨무늬장해 발생률, 그리고 polygalcturanase(PG) 유전자 발현으로 확인하였다. 수확후 ‘력광’은 질소 세 시비구 모두 유사한 성숙기에 도달하였으나, ‘청옥’은 기준 시비한 배추에 비해 2배 시비한 경우 생육이 빠르게 진행되었다. 질소시비에 대한 PG 유전자의 발현양상은 ‘력광’에서는 수확 직후 및 저장 중 PG 유전자의 발현 정도가 거의 차이가 나지 않은 반면, ‘청옥’에서는 3주와 6주 사이 PG 유전자들의 발현이 증가함을 확인하였다. 또한 ‘청옥’에서는 저장 3주와 6주 사이에 1/2 시비구에서 PG 유전자의 발현이 낮았다. ‘력광’은 외관상 품질이 유지되는 것으로 판단되는 6주까지는 세 시비구 모두 Hunter L값이 높게 유지되었으나, 저장 9주차에 Hunter L값의 저하가 심해지는 것이 관찰되었다. 기준 시비 시 저장 9주째에 ‘청옥’ 배추의 외관상 상품성을 유지하는 품질 수준을 보였고 1/2 및 2배 질소 시비는 저장 9주가 경과되면서 외관상 품질이 열악하여 상품성을 상실하였다. 가용성 당함량은 ‘력광’에 비해 ‘청옥’이 높으며, glucose가 fructose보다 비율이 높았다. 질소시비량에 따른 차이는 두 품종 모두 초기에 질소 2배 시비구에서 당함량이 낮았다. 두 품종 모두 질소시비량이 기준 시비량보다 적거나 많으면 수확 시에도 깨씨무늬장해가 발생하였다. ‘력광’은 질소를 2배 시비할 경우 그리고 ‘청옥’은 질소 를 1/2배 시비할 경우 그 증상이 심하였다. 이상의 결과로 질소 2배 시비 및 부족은 배추의 저장성을 약화시키며 기준 질소량(48kg/10a)을 시비하면 ‘력광’의 경우 6주, ‘청옥’은 9주까지 품질유지가 가능하였다. The study was conducted to investigate the effects of nitrogen fertilization on the occurrence of black speck and storability of kimchi cabbage ‘Cheongock’ and ‘Ryouckgwang’s. Kimchi cabbage was cultivated with three different levels of nitrogen fertilization: half, normal, or double (24, 48, or 96 kg/10 a). Quality parameters measured were reducing sugar (glucose and fructose) content, color (Hunter L, a, and b), occurrence of black speck, and gene expression of polygalacturonase (PG ). At harvest, ‘Ryeokgwang’ showed similar maturity at all nitrogen fertilization levels, whereas double nitrogen fertilization induced fast-paced growth in ‘Cheongock’ compared to the normal fertilization. Expression of PG was not significant difference in ‘Ryeokgwang’, PG was expressed more extensively in the ‘Cheongok’ compared to ‘Ryeokgwang’ and expression increased between 3 and 6 weeks of storage. The hunter L value in the ‘Ryeokgwang’ was maintained until 6 weeks, which was the recommended optimal storage period, however it gradually decreased up to 9 weeks. By contrast, normal level of fertilization with nitrogen maintained quality until 9 weeks in ‘Cheongock’. The reducing sugar contents of ‘Cheongock’ were higher than those of ‘Ryeokgwang’, with glucose more abundant than fructose. Double fertilization led to lower soluble sugar contents in both s. Occurrence of black speck was related to the amount of nitrogen fertilization. Black speck was more severe with double excess and lack of nitrogen fertilization in ‘Ryeokgwang’ and ‘Cheongock’s, respectively. In conclusion, normal nitrogen fertilization maintained the quality of kimchi cabbage until 6 and 9 weeks in ‘Ryeokgwang’ and ‘Cheongock’, respectively.

Changes in Clinicopathological Characteristics of Renal Cell Carcinoma in the Past 25 Years: A Single-Center Experience

Choi, Jin Bong,Yoon, Byung Il,Kim, Su Jin,Cho, Hyuk Jin,Hong, Sung-Hoo,Choi, Yeong Jin,Kim, Sae Woong,Hwang, Tae-Kon,Lee, Ji Youl 대한비뇨기과학회 2011 Investigative and Clinical Urology Vol.52 No.2

<P><B>Purpose</B></P><P>We examined changes in the clinicopathologic characteristics of renal cell carcinoma (RCC) in the past 25 years and aimed to obtain indicators for its diagnosis and treatment.</P><P><B>Materials and Methods</B></P><P>The medical records of 563 patients with confirmed primary RCC after surgical treatment from 1985 to 2010 at Seoul St. Mary's Hospital were retrospectively reviewed. Patient and tumor characteristics were compared over 3 time periods (period 1: 1985-1994, period 2: 1995-2004, period 3: 2005-2010).</P><P><B>Results</B></P><P>Period 1 included 65 patients, period 2 included 183 patients, and period 3 included 315 patients, showing an exponential growth in the number of patients. Frequency was highest in the late 50s age group. The review of clinical symptoms showed that incidental diagnosis increased significantly. The tumor size at diagnosis gradually decreased and the proportion of small tumors less than 4 cm increased remarkably. Concerning tumor spread, organ-confined tumors (T<SUB>1-2</SUB>N<SUB>0</SUB>M<SUB>0</SUB>) increased and distant metastasis decreased. Histologically, the clear cell type made up the greatest proportion, about 90% in each period, but subtypes besides the clear cell type increased over the study period. The rate of nephron-sparing surgery increased, and exophytic masses were the most common.</P><P><B>Conclusions</B></P><P>Our review of the recent 25 year's worth of data on RCC from Seoul St. Mary's Hospital showed that the incidental diagnosis of RCC increased over the study period in accordance with the development of screening tests. Tumor size decreased in accordance with the progress in imaging modalities. In the future, multicenter research will be needed to analyze the characteristics of whole renal cancer in Korea.</P>

국내에서 생산된 Blueberry 4개 품종 과실의 유통중 품질 변화

홍세진(Sae Jin Hong),용영록(Young Rog Yeoung),홍순철(Sun Chul Hong),이미림(Mi Rim Lee),엄병헌(Byung Hun Um) 한국원예학회 2007 한국원예학회 학술발표요지 Vol.2007 No.6