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Sö,derhä,ll, Irene,Wu, Chenglin,Novotny, Marian,Lee, Bok Luel,Sö,derhä,ll, Kenneth American Society for Biochemistry and Molecular Bi 2009 The Journal of biological chemistry Vol.284 No.10
<P>Melanization is an important immune component of the innate immune system of invertebrates and is vital for defense as well as for wound healing. In most invertebrates melanin synthesis is achieved by the prophenoloxidase-activating system, a proteolytic cascade similar to vertebrate complement. Even though melanin formation is necessary for host defense in crustaceans and insects, the process needs to be tightly regulated because of the hazard to the animal of unwanted production of quinone intermediates and melanization in places where it is not suitable. In the present study we have identified a new melanization inhibition protein (MIP) from the hemolymph of the crayfish, Pacifastacus leniusculus. Crayfish MIP has a similar function as the insect MIP molecule we recently discovered in the beetle Tenebrio molitor but interestingly has a completely different sequence. Crayfish MIP as well as Tenebrio MIP do not affect phenoloxidase activity in itself but instead interfere with the melanization reaction from quinone compounds to melanin. Importantly, crayfish MIP in contrast to Tenebrio MIP contains a fibrinogen-like domain, most similar to the substrate recognition domain of vertebrate l-ficolins. Surprisingly, an Asp-rich region similar to that found in ficolins that is likely to be involved in Ca2+ binding is present in crayfish MIP. However, crayfish MIP did not show any hemagglutinating activity as is common for the vertebrate ficolins. A mutant form of MIP with a deletion lacking four Asp amino acids from the Asp-rich region lost most of its activity, implicating that this part of the protein is involved in regulating the prophenoloxidase activating cascade. Overall, a new negative regulator of melanization was identified in freshwater crayfish that shows interesting parallels with proteins (i.e. ficolins) involved in vertebrate immune response.</P>
Two-hole structure outsideNi78: Existence of aμsisomer ofCo76andβdecay intoNi76
Sö,derströ,m, P.-A.,Nishimura, S.,Xu, Z. Y.,Sieja, K.,Werner, V.,Doornenbal, P.,Lorusso, G.,Browne, F.,Gey, G.,Jung, H. S.,Sumikama, T.,Taprogge, J.,Vajta, Zs.,Watanabe, H.,Wu, J.,Baba, H.,Dom American Physical Society 2015 PHYSICAL REVIEW C - Vol.92 No.5
Sö,derströ,m, P.-A.,Walker, P.M.,Wu, J.,Liu, H.L.,Regan, P.H.,Watanabe, H.,Doornenbal, P.,Korkulu, Z.,Lee, P.,Liu, J.J.,Lorusso, G.,Nishimura, S.,Phong, V.H.,Sumikama, T.,Xu, F.R.,Yagi, A.,Zha North-Holland Pub. Co 2016 Physics letters. Section B Vol.762 No.-
<P><B>Abstract</B></P> <P>A detailed study of the structure of the doubly mid-shell nucleus Dy 104 1 66 170 has been carried out, following isomeric and <I>β</I> decay. We have measured the yrast band up to the spin-parity <SUP> J π </SUP> = <SUP> 6 + </SUP> state, the K = 2 <I>γ</I>-vibration band up to the <SUP> 5 + </SUP> state, a low-lying negative-parity band based on a <SUP> 2 − </SUP> state that could be a candidate for the lowest energy octupole vibration state within this nucleus, and a candidate for the <SUP> K π </SUP> = <SUP> 6 + </SUP> two quasi-particle isomer. This state was determined to have an excitation energy of 1643.91(23) keV and a half life of 0.99(4) μs, with a reduced hindrance for its decay to the ground-state band an order of magnitude lower than predicted by <SUB> N p </SUB> <SUB> N n </SUB> systematics. This is interpreted as being due to <I>γ</I>-vibrational mixing from a near degeneracy of the isomer and the <SUP> 6 + </SUP> state of the <I>γ</I> band. Furthermore, the parent nucleus <SUP>170</SUP>Tb has been determined to have a half-life of 0.91 ( − 13 + 18 ) s with a possible spin-parity of <SUP> 2 − </SUP> .</P>
Irradiation testing of enhanced uranium oxide fuels
Insulander Bjö,rk, Klara,Kelly, Julian F.,Vitanza, Carlo,Drera, Saleem S.,Holcombe, Scott,Tverberg, Terje,Tuomisto, Harri,Wright, Jonathan,Sarsfield, Mark,Blench, Trevor,Yang, Jae Ho,Kim, Hyun-Gil Elsevier 2019 Annals of nuclear energy Vol.125 No.-
<P><B>Abstract</B></P> <P>Enhanced uranium oxide fuel types are being tested in the Halden Research Reactor in Norway with the aim is to assess the effect that these enhancements have on fuel performance. Fuel temperatures, rod pressures and dimensional changes are being monitored online and an extensive post-irradiation examination programme is planned. Preliminary data show that fuel centerline temperatures can be lowered by addition of ThO<SUB>2</SUB> to the fuel matrix, or by incorporating Cr or SiO<SUB>2</SUB>-TiO<SUB>2</SUB> as a network structure within the fuel. In parallel, two types of cladding coatings are tested in order to investigate their in-core properties. No abnormal behaviour has been noted during the first 100 days of irradiation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Irradiation testing of uranium oxide fuel enhanced with Cr, SiO<SUB>2</SUB>/TiO<SUB>2</SUB> and ThO<SUB>2</SUB>. </LI> <LI> Irradiation testing of cladding coated with (Fe,Cr,Al) and (Cr,Al) alloys. </LI> <LI> All tested materials perform as expected, or better. </LI> <LI> Lowered fuel temperatures observed for fuel enhanced with Cr microcell structure. </LI> <LI> Unexpectedly low temperatures observed for SiO<SUB>2</SUB>/TiO<SUB>2</SUB> and 40% ThO<SUB>2</SUB> enhanced fuel. </LI> </UL> </P>
Lee, Jung Tae,Zhao, Youyang,Thieme, Sö,ren,Kim, Hyea,Oschatz, Martin,Borchardt, Lars,Magasinski, Alexandre,Cho, Won‐,Il,Kaskel, Stefan,Yushin, Gleb WILEY‐VCH Verlag 2013 ADVANCED MATERIALS Vol.25 No.33
<P><B>Novel nanostructured sulfur (S)–carbide derived carbon (CDC) composites</B> with ordered mesopores and high S content are successfully prepared for lithium sulfur batteries. The tunable pore‐size distribution and high pore volume of CDC allow for an excellent electrochemical performance of the composites at high current densities. A higher electrolyte molarity is found to enhance the capacity utilization dramatically and reduce S dissolution in S‐CDC composite cathodes during cycling.</P>
Lee, Sangsik,Oh, Seunghee,Yang, Aerin,Kim, Jihyo,Sö,ll, Dieter,Lee, Daeyoup,Park, Hee‐,Sung WILEY‐VCH Verlag 2013 Angewandte Chemie Vol.125 No.22
<P><I><B>Einen selektiven Phosphoserin‐Einbau</B></I> beschreiben H.‐S. Park et al. in ihrer Zuschrift S. 5883 ff. Eine allgemeine Strategie für den Aufbau rekombinanter Histone mit ortsspezifischer Serinphosphorylierung wurde entwickelt, die auf der Modifizierung einer Phosphoseryl‐tRNA‐Synthetase (SepRS) und des Elongationsfaktors Tu (EF‐Tu) beruht. Die Methode dürfte die Erforschung der Histonphosphorylierung und kreuzregulatorischer Mechanismen vereinfachen.</P>
Morphological Properties of Slender Ca ${\rm{II}}$ H Fibrils Observed by Sunrise II
Gafeira, R.,Lagg, A.,Solanki, S. K.,Jafarzadeh, S.,Noort, M. van,Barthol, P.,Rodrí,guez, J. Blanco,Iniesta, J. C. del Toro,Gandorfer, A.,Gizon, L.,Hirzberger, J.,Knö,lker, M.,Suá,rez, American Astronomical Society 2017 The Astrophysical journal Supplement series Vol.229 No.1
<P>We use seeing-free high spatial resolution Ca II H data obtained by the SUNRISE observatory to determine properties of slender fibrils in the lower solar chromosphere. In this work we use intensity images taken with the SUFI instrument in the Ca II H line during the second scientific flight of the SUNRISE observatory to identify and track elongated bright structures. After identification, we analyze theses structures to extract their morphological properties. We identify 598 slender Ca II H fibrils (SCFs) with an average width of around 180 km, length between 500 and 4000 km, average lifetime of approximate to 400 s, and average curvature of 0.002 arcsec(-1). The maximum lifetime of the SCFs within our time series of 57 minutes is approximate to 2000 s. We discuss similarities and differences of the SCFs with other small-scale, chromospheric structures such as spicules of type I and II, or Ca II K fibrils.</P>
Beiyuan, Jingzi,Tsang, Daniel C.W.,Valix, Marjorie,Baek, Kitae,Ok, Yong Sik,Zhang, Weihua,Bolan, Nanthi S.,Rinklebe, Jö,rg,Li, Xiang-Dong Elsevier 2018 CHEMOSPHERE - Vol.205 No.-
<P><B>Abstract</B></P> <P>Chelant-enhanced soil washing, such as EDTA (ethylenediaminetetraacetic acid) and biodegradable EDDS ([<I>S,S</I>]-ethylene-diamine-disuccinic acid), has been widely studied, however, EDTA is persistent under natural conditions while EDDS has a low efficiency for Pb extraction. Therefore, we investigated the efficacy of mixed chelants (EDDS and EDTA mixture at 1:1 M ratio) for the removal of Cu, Zn, and Pb from a field-contaminated soil using various washing schemes (multi-pulse, step-gradient chelant, and continuous washing schemes). Speciation modelling of the target metals, mineral elements, and EDDS/EDTA was performed, while the leachability and bioaccessibility of residual metals in the treated soils were also assessed. Our results suggested that the combined use of EDDS and EDTA reached equivalent extraction efficiency of the target metals as EDTA, i.e., 50% reduction in the dosage of EDTA was made possible. This was accomplished by selective extraction of Cu by EDDS and Pb by EDTA, which was supported by the results of speciation calculation. Multi-pulse washing scheme with intermittent water rinsing steps removed entrapped metal-chelant complexes and free chelants, therefore reducing the leachability and bioaccessibility of residual metals in the treated soils. Step-gradient chelant washing with the maximum dosage of chelants in the first washing step only achieved marginal improvement but undesirably promoted Pb bioaccessibility. Continuous washing for 24 h enhanced metal extraction but promoted mineral dissolution, together with a large amount of uncomplexed chelants and increase in Cu leachability. Thus the combined use of EDDS and EDTA in multi-pulse washing is recommended for further studies.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Mixture of EDDS and EDTA extracted comparable amount of PTEs as EDTA washing. </LI> <LI> Mixed chelants allowed complementary metal complexation and higher efficiency. </LI> <LI> Multi-pulse washing better utilized chelants and reduced leachability/bioaccessibility. </LI> <LI> Step-gradient chelant dosage hardly improved extraction but increased bioaccessible Pb. </LI> <LI> Continuous washing increased amounts of uncomplexed chelants and dissolved minerals. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
The 72-h WEBT microvariability observation of blazar S5 0716 + 714 in 2009
Bhatta, G.,Webb, J. R.,Hollingsworth, H.,Dhalla, S.,Khanuja, A.,Bachev, R.,Blinov, D. A.,Bö,ttcher, M.,Bravo Calle, O. J. A.,Calcidese, P.,Capezzali, D.,Carosati, D.,Chigladze, R.,Collins, A.,Colo EDP Sciences 2013 Astronomy and astrophysics Vol.558 No.-