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The Biometric Prison: Technological Advancements in Tracking Inmates and Staff
Walker,Jeffrey T.,Rocio Roles 아시아교정포럼 2012 교정담론 Vol.6 No.1
이 연구는 교도소에서 바이오메트릭 기술의 이용의 기본을 다룬다. 이를 위해 먼저 출입통제의 역사와 바이오메트릭 기술을 소개한다. 그리고 현재의 바이오메트릭 기술과 이것이 교도소의 작동을 어떻게 변화시키는지를 다룬다. 바이오메트릭 시스템을 현장에서 사용하는 것은 이 연구의 제 삼장에서 다룬다. 미래의 바이오메트릭 기술 및 기술의 발달과 함께 앞으로 교도소가 어떻게 변할지를 살펴보며 마무리 짓는다.
Walker, Alexander M.,Hayes, Robert P.,Youn, Buhyun,Vermerris, Wilfred,Sattler, Scott E.,Kang, ChulHee American Society of Plant Biologists 2013 PLANT PHYSIOLOGY - Vol.162 No.2
<P><I>The catalytic mechanism and exact specificity for hydroxycinnamoyltransferase from sorghum were determined by comprehensive approaches with crystal structures of apo-form and ternary product complex, site-directed mutagenesis, and kinetic and thermodynamic analyses.</I></P>
High-resolution metabolomics of occupational exposure to trichloroethylene
Walker, Douglas I,Uppal, Karan,Zhang, Luoping,Vermeulen, Roel,Smith, Martyn,Hu, Wei,Purdue, Mark P,Tang, Xiaojiang,Reiss, Boris,Kim, Sungkyoon,Li, Laiyu,Huang, Hanlin,Pennell, Kurt D,Jones, Dean P,Rot Oxford University Press 2016 International journal of epidemiology Vol.45 No.5
<P><B>Background:</B> Occupational exposure to trichloroethylene (TCE) has been linked to adverse health outcomes including non-Hodgkin’s lymphoma and kidney and liver cancer; however, TCE’s mode of action for development of these diseases in humans is not well understood.</P><P><B>Methods:</B> Non-targeted metabolomics analysis of plasma obtained from 80 TCE-exposed workers [full shift exposure range of 0.4 to 230 parts-per-million of air (ppm<SUB>a</SUB>)] and 95 matched controls were completed by ultra-high resolution mass spectrometry. Biological response to TCE exposure was determined using a metabolome-wide association study (MWAS) framework, with metabolic changes and plasma TCE metabolites evaluated by dose-response and pathway enrichment. Biological perturbations were then linked to immunological, renal and exposure molecular markers measured in the same population.</P><P><B>Results:</B> Metabolic features associated with TCE exposure included known TCE metabolites, unidentifiable chlorinated compounds and endogenous metabolites. Exposure resulted in a systemic response in endogenous metabolism, including disruption in purine catabolism and decreases in sulphur amino acid and bile acid biosynthesis pathways. Metabolite associations with TCE exposure included uric acid (<I>β</I> = 0.13, <I>P</I>-value = 3.6 × 10<SUP>−5</SUP>), glutamine (<I>β</I> = 0.08, <I>P</I>-value = 0.0013), cystine (<I>β</I> = 0.75, <I>P</I>-value = 0.0022), methylthioadenosine (<I>β</I> = −1.6, <I>P</I>-value = 0.0043), taurine (<I>β</I> = −2.4, <I>P</I>-value = 0.0011) and chenodeoxycholic acid (<I>β</I> = −1.3, <I>P</I>-value = 0.0039), which are consistent with known toxic effects of TCE, including immunosuppression, hepatotoxicity and nephrotoxicity. Correlation with additional exposure markers and physiological endpoints supported known disease associations.</P><P><B>Conclusions:</B> High-resolution metabolomics correlates measured occupational exposure to internal dose and metabolic response, providing insight into molecular mechanisms of exposure-related disease aetiology.</P>
AN ITERATIVE METHOD FOR SYMMETRIC INDEFINITE LINEAR SYSTEMS
Walker, Homer-F.,Yi, Su-Cheol Korean Mathematical Society 2004 대한수학회논문집 Vol.19 No.2
For solving symmetric systems of linear equations, it is shown that a new Krylov subspace method can be obtained. The new approach is one of the projection methods, and we call it the projection method for convenience in this paper. The projection method maintains the residual vector like simpler GMRES, symmetric QMR, SYMMLQ, and MINRES. By studying the quasiminimal residual method, we show that an extended projection method and the scaled symmetric QMR method are equivalent.
Walker, Bright,Liu, Jianhua,Kim, Chunki,Welch, Gregory C.,Park, Jin Keun,Lin, Jason,Zalar, Peter,Proctor, Christopher M.,Seo, Jung Hwa,Bazan, Guillermo C.,Nguyen, Thuc-Quyen The Royal Society of Chemistry 2013 ENERGY AND ENVIRONMENTAL SCIENCE Vol.6 No.3
<P>We report a series of solution-processable, small-molecule, donor materials based on an architecture consisting of two diketopyrrolopyrrole (DPP) cores with different aromatic π-bridges between the DPP units and different end-capping groups. In general, this architecture leads to desirable light absorption and electronic levels for donor materials. Out of the compounds investigated, a material with a hydrolyzed dithieno(3,2-<I>b</I>;2′,3′-<I>d</I>)silole (SDT) core and 2-benzofuran (BFu) end capping groups leads to the most favorable properties for solar cells, capable of generating photocurrent up to 800 nm while producing an open-circuit voltage of over 850 mV, indicating a small loss in electrical potential compared to other bulk heterojunction systems. Device properties can be greatly improved through the use of solvent additives such as 2-chloronaphthalene and initial attempts to optimize device fabrication have resulted in power conversion efficiencies upwards of 4%.</P> <P>Graphic Abstract</P><P>A series of small-molecule donor materials based on an architecture consisting of two diketopyrrolopyrrole (DPP) moieties with different core and end groups is reported. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3ee24351f'> </P>
Walker Gregory B.,Wang Alick P.,Hadwen Jeremiah,Erdenebold Undrakh-Erdene,Bebedjian Razmik,Sullivan Patrick,Santos Marlise P.,Chenier Chad,Karwaski Stephen,Caron Katie,Varga Gabriella,Lyon Jennifer,Le 대한신경중재치료의학회 2023 Neurointervention Vol.18 No.1
We describe a minimally invasive endovascular approach to treat an arteriovenous fistula of the scalp. We performed a direct puncture of the lesion through the patient’s scalp for liquid embolic agent injection along with external compression of the superficial temporal artery to perform a “manual pressure-cooker technique.” The combination of these minimally invasive techniques resulted in an excellent clinical and radiographic outcome.
Hybrid microcatheter angioplasty for refractory cerebral vasospasm
Walker Melanie,Erdoes Morgan P.,Stricker Chloe G.,Bothell Julie,Kelly Cory M.,Levitt Michael R. 대한뇌혈관외과학회 2021 Journal of Cerebrovascular and Endovascular Neuros Vol.23 No.2
Cerebral vasospasm is a significant cause of morbidity and mortality associated with aneurysmal subarachnoid hemorrhage (aSAH). Intra-arterial chemical and mechanical angioplasty, performed alone or in combination, have been shown to ameliorate cerebral vasospasm and improve patient outcomes. Few options exist for patients who fail these traditional endovascular tactics. We propose a hybrid microcatheter technique that combines the mechanical benefit of transient high pressure induced by microcatheter fluid bolus with a low-dose vasodilator infusion. Five patients with moderate to severe symptomatic vasospasm who failed medical and traditional endovascular management were treated using a hybrid microcatheter technique. All angioplasty procedures were technically successful, and the degree of vasospasm improved following angioplasty. There were no complications related to the cerebral angioplasty procedures. None of the patients required repeat endovascular intervention. Hybrid microcatheter angioplasty may be a useful complement to mechanical or pharmacological techniques in the endovascular management of intractable cerebral vasospasm after aSAH.
An Extended Theory of Scalars Inspired by Supersymmetry
Walker, M.L. 경희대학교 자연과학종합연구원 2003 자연과학논문집 Vol.9 No.2
If supersymmetry is a fundamental symmetry of nature then it can only be exact at energies greater than the electroweak scale. Nonetheless, after supersymmetry breaking the particle spectrum should remain unchanged, although the particle masses will be altered. In particular, the auxiliary fields of scalar particles must either be absorbed somehow by the symmetry breaking process or remain afterwards. Current quantum field theories with scalar fields assume them to have no off mass-shell degrees of freedom, making them unique amongst quantum fields. Supersymmetry accomodates this by including auxiliary fields, which are expressed as functions of the other fields on mass-shell, effectively removing their degrees of freedom. We argue that the auxiliary fields should still be present off mass-shell, even after supersymmetry breaking, and present an appropriate notation for this situation. We then argue by analogy with supersymmetric QED that these auxiliary components should make a contribution to quantum corrections at two loops and higher.