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      • KCI등재

        A Non-Uniform Predictor-Observer for a Networked Control System

        Angel Cuenca,Pedro García,Pedro Albertos,Julián Salt 제어·로봇·시스템학회 2011 International Journal of Control, Automation, and Vol.9 No.6

        This paper presents a Non-Uniform Predictor-Observer (NUPO) based control approach in order to deal with two of the main problems related to Networked Control Systems (NCS) or Sensor Networks (SN): time-varying delays and packet loss. In addition, if these delays are longer than the sampling period, the packet disordering phenomenon can appear. Due to these issues, a (scarce) non-uniform, delayed measurement signal could be received by the controller. But including the NUPO proposal in the control system, the delay will be compensated by the prediction stage, and the non-available data will be reconstructed by the observer stage. So, a delay-free, uniformly sampled controller design can be adopted. To ensure stability, the predictor must satisfy a feasibility problem based on a time-varying delay-dependent condition expressed in terms of Linear Matrix Inequalities (LMI). Some aspects like the relation between network delay and robustness/performance trade-off are empirically studied. A simulation example shows the benefits (robustness and control performance improvement) of the NU-PO approach by comparison to another similar proposal.

      • KCI등재

        Effect of stress during slaughter on carcass characteristics and meat quality in tropical beef cattle

        Carrasco-García Apolo A.,Pardío-Sedas Violeta T.,León-Banda Gloria G.,Ahuja-Aguirre Concepción,Paredes-Ramos Pedro,Hernández-Cruz Bertha C.,Murillo Vicente Vega 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.10

        Objective: This study aimed to determine the effects of stress during slaughter of beef cattle on physiological parameters, carcass, and meat quality at a Federal Inspection Type slaughterhouse located in the southeast of Mexico. Methods: A total of 448 carcasses of male Zebu×European steers with an average age of 36 months were included. Carcass assessment of presence of bruises and bruise characteristics was carried out on each half-carcass. Blood variable indicators of stress (packed cell volume, neutrophil to lymphocyte ratio, glucose, cortisol concentration) and meat quality parameters (pH, color, shear force, drip loss) were evaluated. Results: Of the 448 carcasses evaluated, 81% of the carcasses showed at least one bruise; one bruise was detected in 36.6% and two bruises in 27.0% of animals. Of the 775 bruises found, 69.2% of the bruises were grade 1 in region 3. Of the 448 carcasses studied, 69.6% showed hyperglycemia (6.91 mmol/L); 44.3% and 22.7% showed high (74.7 ng/mL) and extremely high (108.8 ng/mL) cortisol levels, respectively, indicative of inadequate handling of animals during preslaughter and slaughter. Of the carcasses evaluated, 90.4% had a pH ≥5.8 with an average of pH 6.3. In both pH groups, meat samples showed L* values >37.0 (81.6%) and a shear force >54.3 N; meat pH≥5.8 group showed a drip loss of 2.5%. These findings were indicative of dark, firm, and dry (DFD) meat. According to principal component analysis, grades 1 and 2 bruises in region 3 and grade 1 bruises in region 5 were highly associated with cortisol, drip loss, and color parameters b* and h* and were negatively associated with L*, a*, and C*. Conclusion: The bruises probably caused by stress-inducing situations triggered DFD meat. Appropriate changes in handling routines in operating conditions should be made to minimize stress to animals during the slaughter process to improve animal welfare and meat quality.

      • KCI등재

        Factorial design approach to assess the effect of fiber–matrix adhesion on the IFSS and work of adhesion of carbon fiber/polysulfone-modified epoxy composites

        Cauich-Cupul Javier I.,Herrera-Franco Pedro J.,García-Hernández Edgar,Moreno-Chulim Veronica,Valadez-González Alex 한국탄소학회 2019 Carbon Letters Vol.29 No.4

        A two-level full factorial design 22 with three replications was employed to assess the effect of the incorporation of PSF into the epoxy matrix and the surface treatment of carbon fibers on the work of adhesion (WA) and the interfacial shear strength (IFSS) of carbon fiber–epoxy composites. The IFSS was determined using the microbond (or microdrop) micromechanical test, and the work of adhesion was estimated using two different procedures: (1) using the Owens and Wendt method, and (2) from the Dupre–Young expression using the contact angle θ of a cured epoxy resin on a single carbon fiber and the surface energy of the cured epoxy resin. It was found that the treatment of the carbon fiber with the silane-coupling agent appreciably increases its polar component because of the nitric acid oxidation and the chemisorption of the silane-coupling agent onto the carbon fiber surface. Also, the O=S=O group present in the polysulfone chain resin fairly increases the polar component of the epoxy–PSF blend. The results show that the wetting of the silane-treated carbon fiber by the thermoplastic-modified epoxy resin is better, thus increasing the fiber–matrix adhesion. It was also found that there is a similarity between the trends of both, the IFSS and the WA results. Also, from the ANOVA results it was also seen that both the incorporation of the PSF to the epoxy matrix and the surface treatment of the carbon fibers and their interaction were statistically significant to the IFSS and the WA.

      • SCIESCOPUSKCI등재

        Factorial design approach to assess the effect of fiber–matrix adhesion on the IFSS and work of adhesion of carbon fiber/ polysulfone‑modified epoxy composites

        Javier I. Cauich‑Cupul,Pedro J. Herrera‑Franco,Edgar García‑Hernández,Veronica Moreno‑Chulim,Alex Valadez‑González 한국탄소학회 2019 Carbon Letters Vol.29 No.4

        A two-level full factorial design 22 with three replications was employed to assess the effect of the incorporation of PSF into the epoxy matrix and the surface treatment of carbon fibers on the work of adhesion (WA) and the interfacial shear strength (IFSS) of carbon fiber–epoxy composites. The IFSS was determined using the microbond (or microdrop) micromechanical test, and the work of adhesion was estimated using two different procedures: (1) using the Owens and Wendt method, and (2) from the Dupre–Young expression using the contact angle θ of a cured epoxy resin on a single carbon fiber and the surface energy of the cured epoxy resin. It was found that the treatment of the carbon fiber with the silane-coupling agent appreciably increases its polar component because of the nitric acid oxidation and the chemisorption of the silane-coupling agent onto the carbon fiber surface. Also, the O=S=O group present in the polysulfone chain resin fairly increases the polar component of the epoxy–PSF blend. The results show that the wetting of the silane-treated carbon fiber by the thermoplastic-modified epoxy resin is better, thus increasing the fiber–matrix adhesion. It was also found that there is a similarity between the trends of both, the IFSS and the WA results. Also, from the ANOVA results it was also seen that both the incorporation of the PSF to the epoxy matrix and the surface treatment of the carbon fibers and their interaction were statistically significant to the IFSS and the WA.

      • KCI등재

        Hybrid Approach with Combining Cuckoo-Search and Grey-Wolf Optimizer for Solving Optimal Power Flow Problems

        Bathina Venkateswararao,Devarapalli Ramesh,García Márquez Fausto Pedro 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.3

        An electrical power system is a vast interlocked network that needs a vigilant design to sustain the system with an uninterrupted power flow operation without any restrictions, called optimal power flow (OPF). OPF problem requires robust and fast optimization techniques to volve it due to its complexity. Cuckoo Search (CS) is one method that is being applied in OPF problems, and it has many advantages, e.g., ease use and littler tuning parameters. But it is not good enough, falling into local optimal resolutions and slow converges. Therefore, recently developed Grey Wolf Optimization (GWO) algorithm is used to solve OPF, but it has low accuracy and inadequate local searching ability. To overcome these problems, this paper proposed to combine CS with GWO to create a novel the Hybrid algorithm, called here HCSGWO. The main objective is to deduce the emission, true power generation cost, true power losses, and voltage stability, being a multi-objective problem. THCSGWO are validated by solving the OPF problem considering the calssic IEEE57 bus system. The results are compared with GWO and other algorithms employed in the literature.

      • KCI등재

        The Role of Mitochondrial Dynamic Dysfunction in Age-Associated Type 2 Diabetes

        Vezza Teresa,Díaz-Pozo Pedro,Canet Francisco,de Marañón Aranzazu M.,Abad-Jiménez Zaida,García-Gargallo Celia,Roldan Ildefonso,Solá Eva,Bañuls Celia,López-Domènech Sandra,Rocha Milagros,Víctor Víctor M 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.3

        Mitochondrial dynamics, such as fusion and fission, play a critical role in maintaining cellular metabolic homeostasis. The molecular mechanisms underlying these processes include fusion proteins (Mitofusin 1 [MFN1], Mitofusin 2 [MFN2], and optic atrophy 1 [OPA1]) and fission mediators (mitochondrial fission 1 [FIS1] and dynamin-related protein 1 [DRP1]), which interact with each other to ensure mitochondrial quality control. Interestingly, defects in these proteins can lead to the loss of mitochondrial DNA (mtDNA) integrity, impairment of mitochondrial function, a severe alteration of mitochondrial morphology, and eventually cell death. Emerging evidence has revealed a causal relationship between dysregulation of mitochondria dynamics and age-associated type 2 diabetes, a metabolic disease whose rates have reached an alarming epidemic-like level with the majority of cases (59%) recorded in men aged 65 and over. In this sense, fragmentation of mitochondrial networks is often associated with defects in cellular energy production and increased apoptosis, leading, in turn, to excessive reactive oxygen species release, mitochondrial dysfunction, and metabolic alterations, which can ultimately contribute to β-cell dysfunction and insulin resistance. The present review discusses the processes of mitochondrial fusion and fission and their dysfunction in type 2 diabetes, with special attention given to the therapeutic potential of targeting mitochondrial dynamics in this complex metabolic disorder.

      • KCI등재

        Hyperbaric oxygenation applied before or after mild or hard stress: effects on the redox state in the muscle tissue

        Claudia Carolina Pérez-Castro,Alexandre Kormanovski,Gustavo Guevara-Balcázar,María del Carmen Castillo-Hernández,José Rubén García-Sánchez,Ivonne María Olivares-Corichi,Pedro López-Sánchez,Iván Rubio- 대한약리학회 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.1

        The mechanism is unclear for the reported protective effect of hyperbaric oxygen preconditioning against oxidative stress in tissues, and the distinct effects of hyperbaric oxygen applied after stress. The trained mice were divided into three groups: the control, hyperbaric oxygenation preconditioning, and hyperbaric oxygenation applied after mild (fasting) or hard (prolonged exercise) stress. After preconditioning, we observed a decrease in basal levels of nitric oxide, tetrahydrobiopterin, and catalase despite the drastic increase in inducible and endothelial nitric oxide synthases. Moreover, the basal levels of glutathione, related enzymes, and nitrosative stress only increased in the preconditioning group. The control and preconditioning groups showed a similar mild stress response of the endothelial and neuronal nitric oxide synthases. At the same time, the activity of all nitric oxide synthase, glutathione (GSH) in muscle, declined in the experimental groups but increased in control during hard stress. The results suggested that hyperbaric oxygen preconditioning provoked uncoupling of nitric oxide synthases and the elevated levels of GSH in muscle during this study, while hyperbaric oxygen applied after stress showed a lower level of GSH but higher recovery post-exercise levels in the majority of antioxidant enzymes. We discuss the possible mechanisms of the redox response and the role of the nitric oxide in this process

      • KCI등재

        Complications and local relapse after intraoperative low-voltage X-ray radiotherapy in breast cancer

        Ana Alicia Tejera Hernández,Víctor Manuel Vega Benítez,Juan Carlos Rocca Cardenas,Neith Ortega Pérez,Nieves Rodriguez Ibarria,Juan Carlos Díaz Chico,Juan José García-Granados Alayón,Pedro Pérez Correa 대한외과학회 2020 Annals of Surgical Treatment and Research(ASRT) Vol.98 No.6

        Purpose: To study those factors that influence the occurrence of surgical complications and local relapse in patients intervened for breast cancer and receiving intraoperative radiotherapy. Methods: Observational study on patients intervened for breast cancer with conservative surgery and intraoperative radiotherapy with low-voltage X-ray energy source (INTRABEAM), from 2015 to 2017 with 24 months minimum followup. Variables possibly associated to the occurrence of postoperative complications were analyzed with the Student t-test and the Fisher exact test; P < 0.05 considered significant. Subsequently, the construction of multiple multivariate analysis models began, thus building a logistic regression analysis using the IBM SPSS Statistics ver. 23 software. Local relapse was described. Results: The study included 102 patients, mean age of 61.2 years; mean global size of tumor, 12.2 mm. Complications occurred in 29.4%. Fibrosis was the most frequently observed complication, followed by postoperative seroma. Using a 45 mm or larger applicator were significantly associated with the occurrence of complications. Tumor size 2 cm or larger and reintervention showed borderline significant association. Only one case of local relapse was observed. Conclusion: Certain factors may increase the risk of complication after the use of intraoperative radiotherapy. Using external complementary radiotherapy does not seem to increase the rate of complications. Select patients and the involvement of a multidisciplinary team are essential for achieving good results

      • KCI등재

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