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Hyperbaric oxygen therapy for the treatment of a crush injury of the hand: a case report
Neto Pedro Henry,Ribeiro Zamara Brandão,Pinho Adriano Bastos,Almeida Carlos Henrique Rodrigues de,Maranhão Carlos Alberto de Albuquerque,Goncalves Joaquim da Cunha Campos 대한외상학회 2022 大韓外傷學會誌 Vol.35 No.3
We describe a case of hyperbaric oxygen therapy (HBOt) as an adjunct to treatment of a crush injury to the hand. A 34-year-old male paramedic was involved in a motor vehicle accident and admitted for diagnosis and surgical treatment. He sustained a crush injury to his right hand and presented with significant muscle damage, including multiple fractures and dislocations, an avulsion injury of the flexor tendons, and amputation of the distal phalanx of the little finger. He underwent reconstructive surgery and received HBOt over the following days. In the following 2 months, he lost the distal and middle phalanges of the little finger and recovered hand function. Posttraumatic compartment syndrome responds well to HBOt, which reduces edema and contributes to angiogenesis, as well as promoting the cascade of healing events. High-energy trauma causes massive cell destruction, and the blood supply is usually not sufficient to meet the oxygen demands of viable tissues. Hyperbaric oxygenation by diffusion through interstitial and cellular fluids increases tissue oxygenation to levels sufficient for the host’s responses to injury to work and helps control the delayed inflammatory reaction. HBOt used as an adjunct to surgical treatment resulted in early healing and rehabilitation, accelerating functional recovery. The results suggest that adjunctive HBOt can be beneficial for the treatment of crush injuries of the hand, resulting in better functional outcomes and helping to avoid unnecessary amputations.
A Non-Uniform Predictor-Observer for a Networked Control System
Angel Cuenca,Pedro García,Pedro Albertos,Julián Salt 제어·로봇·시스템학회 2011 International Journal of Control, Automation, and Vol.9 No.6
This paper presents a Non-Uniform Predictor-Observer (NUPO) based control approach in order to deal with two of the main problems related to Networked Control Systems (NCS) or Sensor Networks (SN): time-varying delays and packet loss. In addition, if these delays are longer than the sampling period, the packet disordering phenomenon can appear. Due to these issues, a (scarce) non-uniform, delayed measurement signal could be received by the controller. But including the NUPO proposal in the control system, the delay will be compensated by the prediction stage, and the non-available data will be reconstructed by the observer stage. So, a delay-free, uniformly sampled controller design can be adopted. To ensure stability, the predictor must satisfy a feasibility problem based on a time-varying delay-dependent condition expressed in terms of Linear Matrix Inequalities (LMI). Some aspects like the relation between network delay and robustness/performance trade-off are empirically studied. A simulation example shows the benefits (robustness and control performance improvement) of the NU-PO approach by comparison to another similar proposal.
Fernandez, Maria Elena,Goszczynski, Daniel Estanislao,Prando, Alberto Jose,Peral-Garcia, Pilar,Baldo, Andres,Giovambattista, Guillermo,Liron, Juan Pedro Korean Society of Animal Sciences and Technology 2014 한국축산학회지 Vol.56 No.5
Puberty is a stage of sexual development determined by the interaction of many loci and environmental factors. Identification of genes contributing to genetic variation in this character can assist with selection for early pubertal bulls, improving genetic progress in livestock breeding. Thyroid hormones play an important role in sexual development and spermatogenic function. The objective of this study was to evaluate the association between single nucleotide polymorphisms (SNPs) located in thyroglobulin(TG) gene with age of puberty in Angus bulls. Four SNPs were genotyped in 273 animals using SEQUENOM technology and the association between markers and puberty age was analyzed. Results showed a significant association (P < 0.05) between these markers and puberty age estimated at a sperm concentration of 50 million and a progressive motility of 10%. This is the first report of an association of TG polymorphisms with age of puberty in bulls, and results suggest the importance of thyroidal regulation in bovine sexual development and arrival to puberty.
( Maria Elena Fernandez ),( Daniel Estanislao Goszczynski ),( Alberto Jose Prando ),( Pilar Peral Garcia ),( Andres Baldo ),( Guillermo Giovambattista ),( Juan Pedro Liron ) 한국동물자원과학회(구 한국축산학회) 2014 한국축산학회지 Vol.56 No.17
Puberty is a stage of sexual development determined by the interaction of many loci and environmental factors. Identification of genes contributing to genetic variation in this character can assist with selection for early pubertalbulls, improving genetic progress in livestock breeding. Thyroid hormones play an important role in sexualdevelopment and spermatogenic function. The objective of this study was to evaluate the association betweensingle nucleotide polymorphisms (SNPs) located in thyroglobulin(TG) gene with age of puberty in Angus bulls. FourSNPs were genotyped in 273 animals using SEQUENOM technology and the association between markers andpuberty age was analyzed. Results showed a significant association (P < 0.05) between these markers and pubertyage estimated at a sperm concentration of 50 million and a progressive motility of 10%. This is the first report of anassociation of TG polymorphisms with age of puberty in bulls, and results suggest the importance of thyroidalregulation in bovine sexual development and arrival to puberty.
Nydia Ávila-Vanzzini,Juan Francisco Fritche-Salazar,Nelva Marina Vázquez-Castro,Pedro Rivera-Lara,Oscar Pérez-Méndez,Humberto Martínez-Herrera,Mario Gómez-Sánchez,Alberto Aranda-Frausto,Héctor Herrera 한국심초음파학회 2016 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.24 No.4
Background: Severe aortic stenosis (AS), leads to pathological left ventricular remodeling that may worsen with concomitantoverweight and obesity (OW/O). Methods: We aimed to prospectively analyze the impact of OW/O on ventricular remodeling in severe AS, by evaluating thepercentage of intraendomyocardial fibrosis (PIEF) and the percentage of infiltrating intraendocardial lipid vacuoles (PIELV) andits relationship to global longitudinal strain (GLS) in patients with OW/O. Results: 44 patients with severe AS were included, 13 non-obese (29%) and 31 OW/O (71%), all of them with left ventricularejection fraction ≥ 55%. GLS was evaluated with 2D speckle tracking. During valve replacement, an endocardial biopsy wasobtained, where PIEF and PIELV were analyzed. Patients with higher PIEF and PIELV had greater body mass index (p < 0.0001)and worse GLS (p < 0.0053). A GLS cut-off point < -14% had a sensitivity of 75%, and a specificity of 92.8% to detect importantPIEF (AUC: 0.928, 95% confidence interval: 0.798–1.00). On multivariate analysis, OW/O and PIELV were independentlyassociated to the PIEF, and OW/O and PIEF were independently associated to GLS. A high correlation between the amount ofPIELV and PIEF were found. Conclusion: Patients with severe AS and OW/O have greater PIEF and PIELV, suggesting more pathological remodeling. GLS is useful to detect subclinical myocardial injury and is potentially useful for endomyocardial fibrosis detection. The presenceof higher PIELF may be a trigger factor for the development of intraendomyocardial fibrosis.
Dí,ez, Blanca,Cuadrado, Purificació,n,Marcos-Ferná,ndez, Á,ngel,de la Campa, José,G.,Tena, Alberto,Prá,danos, Pedro,Palacio, Laura,Lee, Young Moo,Alvarez, Cristina Elsevier 2018 Reactive & functional polymers Vol.127 No.-
<P><B>Abstract</B></P> <P>Two series of aromatic poly(<I>ortho</I>-hydroxyamide)s (poly(<I>o</I>-hydroxyamide)s, HPAs) were prepared by reaction of two diamines, 2,2-bis(3-amino-4-hydroxyphenyl) propane (APA) and 2,2-bis(3-amino-4-hydroxyphenyl) hexafluoropropane (APAF), with four aromatic diacid chlorides; terephthaloyl dichloride (TPC), isophthaloyl dichloride (IPC), 2,2-bis[4-chlorocarbonylphenyl)hexafluoropropane (6FC) and 4,4′-sulfonyldibenzoyl dichloride (DBSC). Amorphous HPAs with high molecular weights (inherent viscosities higher than 0.5 dL/g) and relatively high glass transition temperatures (220–280 °C) were obtained. Dense membranes of HPAs were able to undergo a thermal rearrangement (TR) process to polybenzoxazoles (β-TR-PBOs) heating at moderate temperatures (between 250 and 375 °C), and their complete conversion was reached at a temperature below 375 °C, depending on the <I>o</I>-hydroxy diamine moiety, APA and APAF. The β-TR-PBOs films derived from APAF showed a higher thermal stability and higher Tg than those from APA. Gas separation properties of TR-PBOs membranes were superior to those of their poly(<I>o</I>-hydroxyamide) precursors, particularly for the following gas pairs: O<SUB>2</SUB>/N<SUB>2</SUB>, CO<SUB>2</SUB>/CH<SUB>4</SUB>, He/CH<SUB>4</SUB> and He/CO<SUB>2</SUB>.</P>