http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
알루미늄과 헤테로폴리산으로 개질된 메조포러스 실리카 상에서의 AKD 합성
김현국,우창수,최재석,박민태,이병민,이호인 한국공업화학회 2003 응용화학 Vol.7 No.1
AKD(alkyl ketene dimer) used widely as a neutral sizing agent is produced industrially by halogenization of stearic acid followed by dimerization of alkyl ketene. In the present work, to suppress the byproduct of hydrochloric acid and to improve reaction pathway. AKD was prepared through of ketene intermediate by dehydration of stearic acid in gas phase using reaction with silanol on silica as active sites of the catalyst SBA-15 showed the highest activity due to the large and open tubular pores. It was found that main products were dimer and trimer. Our goal of the present work was to increase of the selectivity for the dimer.
酸棗仁이 CT105에 의한 신경세포 상해 및 白鼠의 기억에 미치는 영향
정정욱,박창국,박치상,이소연,윤현덕,신오철 대한본초학회 2005 大韓本草學會誌 Vol.20 No.1
Objective: This study was designed to research whether demonstrate neuroprotective and memory enhancing effects of Z1BU, suggesting its beneficial actions for the treatment of AD. Methods: The present study investigated effects of the dichloromethane extract of Semen Zizyphi Spinosae(ZIBU) on neurotoxicity and reactive oxygen species(ROS) and nitric oxide(NO) formation in PC 12 cell line overexpressed with carboxyl-terminal 105 amino acid peptide fragment of amyloid precursor protein(CT105). In addition, the present study evaluated its radical scavenging activity and effects on acetylcholinesterase(AChE) activity. Furthermore, effects on neuronal loss in CAl area and cognitive deficits induced by scopolamine treatment were also evaluated in rats. Result: we found in this study that ZIBU significantly inhibited apoptotic neuronal death induced by CT105 overexpression in PC12 cells, with the IC_(50) value of 23 ㎍/ml. Based on phase-contrast and fluorescence microscopic examinations, ZIBU reversed morphological changes of CT105-expressed PC-12 cells. It was also found that Z1BU significantly induced neurite outgrowth and inhibited formation of ROS and NO.Z1BU scavenged DPPH radicals and inhibited AChE activity. Furthermore, it attenuated memory impairment induced by the injection of scopolamine in rats, based on passive avoidance test. Crystal violet staining of rat brain slices exhibited increase in the viability of pyramidal neurons in hippocampal CAI area. Conclusion: these results demonstrate neuroprotective and memory enhancing effects of ZIBU, suggesting its beneficial actions for the treatment of AD.
Park, Chang-Bum,Jung, Keum-Dong,Jin, Sung-Hun,Park, Byung-Gook,Lee, Jong-Duk The Korean Infomation Display Society 2005 Journal of information display Vol.6 No.2
Hybrid insulator pentacene thin film transistors (TFTs) are fabricated with thermally grown oxide and cross-linked polyvinylalcohol (PVA) including surface treatment by dilute ploymethylmethacrylate (PMMA) layer on $n^+$ doped silicon wafer. Through the optimization of $SiO_2$ layer thickness in hybrid insulator structure, carrier mobility is increased to more than 35 times than that of the TFT which has only a gate insulator of $SiO_2$ at the same electric field. The carrier mobility of $1.80cm^2$/V-s, subthreshold swing of 1.81 V/decade, and $I_{on}/I_{off}$ current ratio> $1.10{\times}10^5$ are obtained less than -30 V bias condition. The result is one of the best reported performances of pentacene TFTs with hybrid insulator including cross-linked PVA layer as a gate insulator at relatively low voltage operation.
Park, Hyung Seok,Choi, Ji-Yeob,Lee, Mi-Jeong,Park, Seho,Yeo, Chang-Woo,Lee, Sang Seop,Shin, Jae-Gook,Park, Byeong-Woo The Korean Academy of Medical Sciences 2011 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.26 No.8
<P>The aim of the study was to evaluate the association between genetic polymorphisms of <I>CYP2D6</I> and outcomes in breast cancer patients with tamoxifen treatment. We evaluated the <I>CYP2D6</I> genetic polymorphisms in 766 breast cancer patients. Among them, 110 patients whose samples were prospectively collected before surgery and treated with tamoxifen were included to evaluate the association between <I>CYP2D6</I> and outcomes. The genotypes of <I>CYP2D6</I> were categorized as extensive metabolizer (EM), intermediate metabolizer (IM), and poor metabolizer (PM) according to the activity score. The clinicopathologic features of 110 patients were not significantly different among the three groups except for the T-stage and nodal status. The high T-stage and axillary metastasis were more frequent in the PM group. While recurrence-free and overall survival in the PM group was poorer than the other groups, there was no significant difference between the EM and the IM group. The difference between the PM and the other groups on univariate analysis disappeared on multivariate analysis. These conflicting results suggest that the clinical value of <I>CYP2D6</I> polymorphisms is still unclear and more large-sized and comprehensively designed trials are necessary.</P>
Low Cost MEMS-IMU Based DR/GPS Integrated System in Urban Environment
Woo Jung Park,Jae Hong Lee,Chang Ho Kang,Myung Hwan Seo,Sang Yeon Park,Jong Yun Yeo,Jin Woo Song,Chan Gook Park 제어로봇시스템학회 2018 제어로봇시스템학회 국제학술대회 논문집 Vol.2018 No.10
In this paper, we propose an MEMS-IMU Based 10<SUP>th</SUP> order DR/GPS integrated system. Existing low cost MEMS based INS/GPS integrated systems are not applicable to autonomous vehicle localization that needs navigation error under 3m. To improve the performance of the MEMS based navigation system, odometer based DR/GPS formulation was proposed. By substituting MEMS accelerometer to odometer, velocity and position errors of navigation solution are reduced. The proposed method is tested for a land vehicle in urban area including GPS outage section. The experimental results show that the proposed method reduced the navigation error in the GPS outage section than MEMS INS/GPS system.