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Influences of Carbachol on Potassium Channels in Sublingual Acinar Cells of Rat
Shin, Myung-Sang,Park, Kyung-Pyo,Kim, Joong-Soo,Lee, Jong-Heun The Official Publication of Korean Academy of Oral 1996 International Journal of Oral Biology Vol.20 No.1
The Saliva is formed by outflow of potassium ion after calcium ion influx into acinar cell which was activated by secretagogue. The channel related with the outflow of potassium ion channel is one of the channels first studied with patch clamp technique in epithelial cell. Contrary to the many studies of submandibular gland, there has been no work about the electrophysiological study of sublingual gland with patch clamp technique. The sublinqual acinar cells were collected from Spraue-Dawley rat by time-scheduled trypsin and collagenase treatment. To record channel activities, micropipettes filled with HEPES-buffered high potassium solution with 2-5 MΩresistance were used. Membrane currents were recorded by cell attached patch clamp method. 10 μM Acetylcholine(ACh) or 10 μM Carbachol(CCh) was directly added in perfusion solution. The channel activities were recoreded and were evaluated with personal computer on pClamp software. The obtained results were as followed. 1. We could attain the isolated single acinar cells of sublingual gland. 2. The conductance of potassium ion channel was about 190pS and voltage dependent. 3. The the other type of channel was not sensitive to pipette voltage and had small conductance. 4. Addition of ACh or CCh increased the open probability of potassium channels without change of conductance.
A two-step method for the optimum design of trusses with commercially available sections
Oral, Suha,Uz, Atilla Techno-Press 1997 Structural Engineering and Mechanics, An Int'l Jou Vol.5 No.1
A two-step method is presented for the optimum design of trusses with available sections under stress and Euler buckling constraints. The shape design of the truss is used as a means to convert the discrete solution into a continuous one. In the first step of the method, a continuous solution is obtained by sizing and shape design using an approximate polynomial expression for the buckling coefficients. In the second step, the member sizes obtained are changed to the nearest available sections and the truss is reconfigured by using the exact values for the buckling coefficients. The optimizer used is based on the sequential quadratic programming and the gradients are evaluated in closed form. The method is illustrated by two numerical examples.
Oil transportation security in the Black Sea and the Turkish Straits
Oral, Nilufer Jungseok Research Institute of International Logis 2007 JOURNAL OF INTERNATIONAL LOGISTICS AND TRADE Vol.5 No.1
The Black Sea region has become as an important energy transit route for Caspian and Russian oil and natural gas to western markets. Since 1996 the quantity of oil exported from the Black Sea through the Turkish Straits and the number of transiting tankers has doubled and will continue to expand. However, these are also two waterways where the risk of either an accidental or intentional disaster is significant bringing serious repercussions for energy supply security. This paper will analyze measures taken by Black Sea coastal States to provide for secure ports and shipping against accidental and intentional disasters. The paper will examine the role of technology, such as satellite based VTS providers in the Black Sea, implementation of the ISPS Code, the role of the relatively new BlackSeaFor in providing both port and navigational security. The paper will further make recommendations for further improvements for enhancement of security emergency response planning. In addition, the paper will examine current security measures taken by the Turkish Administration for oil transportation through the Turkish Straits.
Sensation Seeking and Creativity in Prospective Educators and Musicians
Günseli Oral 대한사고개발학회 2008 The International Journal of Creativity & Problem Vol.18 No.2
Research demonstrates that creativity and sensation seeking are closely connected. According to the literature, performing artists such as musicians do exhibit higher levels of sensation seeking when compared to other creative groups. The present study investigated the effect of sensation seeking on creativity in 127 Turkish university students in the departments of music and education. The subjects were simultaneously administered Something About Myself (SAM) in the Khatena-Torrance Creative Perception Inventory, and Sensation Seeking Scale from the Zuckerman-Kuhlman Personality Questionnaire. Results demonstrated that sensation seeking did not differ according to school type. A significant influence of sensation seeking on SAM was obtained. Students in the music department had significantly higher scores on artistry dimension, whereas students in the department of elementary school education had significantly higher scores on environmental sensitivity dimension. Similar to previous research findings, sensation seeking was found to be a significant predictor of creativity.
Robust ratio-type estimators in simple random sampling
Evrim Oral,Cem Kadilar 한국통계학회 2011 Journal of the Korean Statistical Society Vol.40 No.4
In sampling theory, ratio-type estimators are extensively used to estimate the population mean when the correlation between study and auxiliary variables is positively high. In this study, we incorporate robust modified maximum likelihood estimators (MMLEs)into Kadilar–Cingi estimators and provide their properties theoretically. We support the theoretical results with simulations under numerous super-population models, and study the robustness properties of these modified estimators. We show that utilization of MMLEs in estimating the mean of a finite population leads to robust estimates, which is very advantageous when we have non-normality or other common data anomalies such as outliers.
Elif Oral,Zekai Halici,Irfan Cinar,Elif Ozcan,Zerrin Kutlu 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.2
Objective: This study investigated changes in urotensin-II (U-II) and endocan levels which can be used as an early biological marker of endothelial injury in the episode and remission phases of bipolar affective disorder (BAD). Methods: We compared endocan and U-II levels, which has been shown to be closely associated with neurotransmitter systems in addition to continuity of endothelial structure and inflammatory response, in patients with BAD in remission for at least one year (n=42) and in patients still in manic or depressive episodes (n=16) with healthy controls (n=30). Results: Both endocan and U-II levels were significantly higher in the bipolar patients than in the controls. Endocan and U-II levels were also significantly correlated with one another (p =0.000, r=0.833). Both endocan (p =0.000) and U-II levels (p =0.000) were significantly higher in the bipolar attack group compared to the subjects in remission, and in the remission group compared to the controls. Conclusion: In this study we determined significantly higher endocan and U-II levels in BAD compared to the controls, while serum endocan and U-II levels of patients undergoing attacks were also significantly higher than those of the controls and also those of patients in remission.
Type A Personality and Creative Problem Solving: The Case of Turkish Prospective Teachers
Gunseli Oral 대한사고개발학회 2005 The International Journal of Creativity & Problem Vol.15 No.1
Creativity and positive personality characteristics are crucial elements particularly for teachers (Torrance, 1994). The present study investigated the relationships between Type A personality pattern of creative problem solving in Turkish prospective teachers. Ninety-two students in Akdeniz University, Faculty of Education, Science and Social Science Teaching Programs participated in the study Type A Scale and Creative Problem Solving Scale were developed by the researcher and applied on the subjects. Linear regression demonstrated that Type A personality predicted creative problem solving negatively (R=.519; R²= .269; p<.01). Enhancement of creativity through increased positive personality characteristics of teachers is suggested and results are discussed in the framework of teacher training in Turkey.