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      • KCI등재

        Metal-Doped In2O3 Nanosphere Arrays with Enhanced Gas-Sensing Property

        Xuanji Zhang,Ni Deng,Xianjia Chen,Yanting Yang,Jing Li,BO HONG,DINGFENG JIN,Xiaoling Peng,XINQING WANG,Hongliang Ge,HONGXIAO JIN 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.3

        In2O3 and metal-doped (Ni or Ce) In2O3 mesoporous three-dimensional (3D) nanospheres arrays were synthesized via nanocasting using mesoporous silica as hard templates. Effects of Ni or Ce doping on the structure, optical and gas-sensing properties of the In2O3 nanospheres were investigated. Both the undoped and the doped In2O3 nanospheres showed single-phase structure without any impurity. The nanospheres were about 20 nm in size and they stacked closely to formrigid 3D mesoporous structure. Achange in the value of optical band gap was observed upon metal doping. The room temperature photo luminescence behavior also showed some differences between pure and doped In2O3. Compared with pure In2O3 nanospheres, the metal-doped In2O3 exhibited superior response, fast recovery and good selectivity to ethanol. The enhanced gas-sensing properties might be related to the doping of metal ion and its effective contribution towards the oxygen vacancies, conductivity and crystallite size of the grains.

      • Automatic cystocele severity grading in transperineal ultrasound by random forest regression

        Ni, Dong,Ji, Xing,Wu, Min,Wang, Wenlei,Deng, Xiaoshuang,Hu, Zhongyi,Wang, Tianfu,Shen, Dinggang,Cheng, Jie-Zhi,Wang, Huifang Elsevier 2017 Pattern recognition Vol.63 No.-

        <P><B>Abstract</B></P> <P>Cystocele is a woman disease that bladder herniates into vagina. Women with cystocele may have problem in urinating and higher risk of bladder infection. The treatment of cystocele highly depends on the severity. The cystocele severity is usually evaluated with the manual transperineal ultrasound measurement for the maximal distance between the bladder and the lower tip of symphysis pubis in the Valsalva maneuver. To improve the efficiency of the measurement, we propose a fully automatic scheme that can measure the distance between the two anatomic structures in each ultrasound image. The whole measurement scheme is realized with a two-phase random forest regression to infer the locations of the two structures in the images for the support of distance measurement. The experimental results suggest automatic distance measurements and the final grading by our random forest regression method are comparable to the measurements and grading scores from three medical doctors, and thus corroborate the efficacy of our method.</P> <P><B>Highlights</B></P> <P> <UL> <LI> First automatically computerized cystocele grading method on the transperineal ultrasound is developed in this study. </LI> <LI> The automatic cystocele grading on the transperineal ultrasound is realized with a two-phase random forest regression model. </LI> <LI> Auto-context features are helpful for our regression model to improve the cystocele grading results. </LI> </UL> </P>

      • SCIESCOPUSKCI등재

        Expression characterization and transcription regulation analysis of porcine Yip1 domain family member 3 gene

        Ni, Dongjiao,Huang, Xiang,Wang, Zhibo,Deng, Lin,Zeng, Li,Zhang, Yiwei,Lu, Dongdong,Zou, Xinhua Asian Australasian Association of Animal Productio 2020 Animal Bioscience Vol.33 No.3

        Objective: The Yip1 domain family (YIPF) proteins were proposed to function in endoplasmic reticulum (ER) to Golgi transport and maintenance of the morphology of the Golgi, which were homologues of yeast Yip1p and Yif1p. YIPF3, the member 3 of YIPF family was a homolog of Yif1p. The aim of present study was to investigate the expression and regulation mechanism of porcine YIPF3. Methods: Quantitative realtime polymerase chain reaction (qPCR) was used to analyze porcine YIPF3 mRNA expression pattern in different tissues and pig kidney epithelial (PK15) cells stimulated by polyinosine-polycytidylic acid (poly [I:C]). Site-directed mutations combined with dual luciferase reporter assays and electrophoretic mobility shift assay (EMSA) were employed to reveal transcription regulation mechanism of porcine YIPF3. Results: Results showed that the mRNA of porcine YIPF3 (pYIPF3) was widely expressed with the highest levels in lymph and lung followed by spleen and liver, while weak in heart and skeletal muscle. Subcellular localization results indicated that it expressed in Golgi apparatus and plasma membranes. Upon stimulation with poly (I:C), the level of this gene was dramatically up-regulated in a time- and concentration-dependent manner. pYIPF3 core promoter region harbored three cis-acting elements which were bound by ETS proto-oncogene 2 (ETS2), zinc finger and BTB domain containing 4 (ZBTB4), and zinc finger and BTB domain containing 14 (ZBTB14), respectively. In which, ETS2 and ZBTB4 both promoted pYIPF3 transcription activity while ZBTB14 inhibited it, and these three transcription factors all played important regulation roles in tumorigenesis and apoptosis. Conclusion: The pYIPF3 mRNA expression was regulated by ETS2, ZBTB4, and ZBTB14, and its higher expression in immune organs might contribute to enhancing ER to Golgi transport of proteins, thus adapting to the immune response.

      • KCI등재

        Ginsenoside Rg3 ameliorates myocardial glucose metabolism and insulin resistance via activating the AMPK signaling pathway

        Jingyu Ni,Zhihao Liu,Miaomiao Jiang,Lan Li,Jie Deng,Xiaodan Wang,Jing Su,Yan Zhu,Feng He,Jingyuan Mao,Xiumei Gao,Guanwei Fan 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.2

        Background: Ginsenoside Rg3 is one of the main active ingredients in ginseng. Here, we aimed to confirm its protective effect on the heart function in transverse aortic coarctation (TAC)-induced heart failure mice and explore the potential molecular mechanisms involved. Methods: The effects of ginsenoside Rg3 on heart and mitochondrial function were investigated by treating TAC-induced heart failure in mice. The mechanism of ginsenoside Rg3 for improving heart and mitochondrial function in mice with heart failure was predicted through integrative analysis of the proteome and plasma metabolome. Glucose uptake and myocardial insulin sensitivity were evaluated using micro-positron emission tomography. The effect of ginsenoside Rg3 on myocardial insulin sensitivity was clarified by combining in vivo animal experiments and in vitro cell experiments. Results: Treatment of TAC-induced mouse models with ginsenoside Rg3 significantly improved heart function and protected mitochondrial structure and function. Fusion of metabolomics, proteomics, and targeted metabolomics data showed that Rg3 regulated the glycolysis process, and Rg3 not only regulated glucose uptake but also improve myocardial insulin resistance. The molecular mechanism of ginsenoside Rg3 regulation of glucose metabolism was determined by exploring the interaction pathways of AMPK, insulin resistance, and glucose metabolism. The effect of ginsenoside Rg3 on the promotion of glucose uptake in IR-H9c2 cells by AMPK activation was dependent on the insulin signaling pathway. Conclusions: Ginsenoside Rg3 modulates glucose metabolism and significantly ameliorates insulin resistance through activation of the AMPK pathway.

      • KCI등재

        Bacillus subtilis devitalization mechanism of atmosphere pressure plasma jet

        Sanxi Deng,Cheng Cheng,Guohua Ni,Yuedong Meng,Hua Chen 한국물리학회 2010 Current Applied Physics Vol.10 No.4

        Bio-applications of atmospheric pressure plasma have been widely studied in recent years. However, the devitalization mechanisms of micro-organisms by atmosphere pressure plasma have not been clearly explained. This paper was to find the possible sterilization mechanisms and define the major sterilization factors with the atmospheric pressure plasma jet. For the sterilization target, the Bacillus subtilis was selected. In this paper, a set of physical or chemical methods were used to characterize the following sterilization factors: heat, ultraviolet radiation, charged species and chemical reactive species generated by the plasma. It was found that the bacterial inactivation efficacy had a significant improvement when oxygen was introduced into the plasma jet system. Comparing with the result of sterilization, the inactivation process was dominantly controlled by synergistic actions of chemically active species and charged species, rather than heat, or ultraviolet radiation.

      • KCI등재

        Principle and Design of a Novel Lorenz Force Type Bearingless Motor with Single-Axis Actively Regulated Capability

        Ding Qiang,Deng Zhiquan,Wang Xiaolin,Wu Guyu,Ni Tuocheng 대한전기학회 2016 Journal of Electrical Engineering & Technology Vol.11 No.5

        This paper proposes a novel Lorenz-force-type bearingless motor with single-axis actively positioned functionality. The novel motor consists of two slotless surface-mounted permanent magnet(SPM) motors, which have six skewed coils for each motor to constitute 3-phase windings and are in tandem along axial direction so as to achieve actively regulated axial motion. Additionally, two repulsive permanent magnet bearings (RPMBs) are used to passively stabilize radial- and tilting movements of the rotor. The slotless stator iron is employed for arrangement of the skewed coils in toroidal form. Compared with state-of-the-art single-axis actively controlled bearingless motors utilizing field weakening or strengthening effect of d-axis current to regulate axial movement, perhaps suffering irreversible demagnetization of permanent magnets especially at the time of start-up, the merit of this proposed motor is beneficial to prevent the demagnetization risk of permanent magnets. To verify the novel concept, firstly, theoretical analysis is carried out for modeling back electromagnetic force (back-EMF), axial force, drive torque. Followed by the analytical model, a detailed design process by integration of analytical method and finite element analysis (FEA) for the structural parameters are revealed. At last, 3-D FEA is performed to validate the correctness of analytical model, design process as well as to evaluate the performance of proposed motor.

      • SCIESCOPUSKCI등재
      • KCI등재후보

        DECONTAMINATION OF NITRATES AND NITRITES IN WASTEWATER BY ZERO-VALENT IRON NANOPARTICLES

        KUEN-SONG LIN,TIEN-DENG CHUANG,NI-BIN CHANG 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2008 NANO Vol.3 No.4

        The chemical reduction of nitrate or nitrite species by zero-valent iron nanoparticle (ZVIN) in aqueous solution and related reaction kinetics or mechanisms using fine structure characterization were investigated. Experimentally, ZVIN of this study was prepared by borohydride reduction method at room temperature. The morphology of as-synthesized ZVIN shows that the nearly ball and ultrafine particles ranged of 20–50 nm were observed with FE-SEM analysis. The kinetic model of nitrites or nitrates reductive reaction by ZVIN is proposed as a pseudo-first-order kinetic equation. The nitrite and nitrate removal efficiencies using ZVIN were found 65–83% and 51–68%, respectively, based on three different initial concentrations. By using XRD patterns, the quantitative relationship between nitrite and Fe(III) or Fe(II) becomes similar to the one between nitrate and Fe(III) in the ZVIN study. The possible reason is linked with a faster nitrite reduction by ZVIN. In fact,the occurrence of the relative faster nitrite reductive reaction suggested that the passivation of the ZVIN have a significant contribution to iron corrosion. The XANES spectra show that the nitrites or nitrates reduce to N₂ while oxidizing the ZVIN to Fe₂O₃ or Fe₃O₄ electrochemically. It is also very clear that decontamination of nitrate or nitrite species in groundwater via the in-situ remediation with a ZVIN permeable reactive barrier would be environmentally attractive.

      • Robotic Dough Shaping

        Jan Ondras,Di Ni,Xi Deng,Zeqi Gu,Henry Zheng,Tapomayukh Bhattacharjee 제어로봇시스템학회 2022 제어로봇시스템학회 국제학술대회 논문집 Vol.2022 No.11

        Robotic manipulation of deformable objects gains great attention due to its wide applications including medical surgery, home assistance, and automatic food preparation. The ability to deform soft objects remains a great challenge for robots due to difficulties in defining the problem mathematically. In this paper, we address the problem of shaping a piece of dough-like deformable material into a 2D target shape presented upfront. We use a 6 degree-of-freedom WidowX-250 Robot Arm equipped with a rolling pin and information collected from an RGB-D camera and a tactile sensor. We present and compare several control policies, including a dough shrinking action, in extensive experiments across three kinds of deformable materials and across three target dough shape sizes, achieving the intersection over union (IoU) of 0.90. Our results show that: i) rolling dough from the highest dough point is more efficient than from the 2D/3D dough centroid; ii) it might be better to stop the roll movement at the current dough boundary as opposed to the target shape outline; iii) the shrink action might be beneficial only if properly tuned with respect to the expand action; and iv) the Play-Doh material is easier to shape to a target shape as compared to Plasticine or Kinetic sand. Video demonstrations of our work are available at https://youtu.be/ZzLMxuITdt4

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