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Narae Kang,Yonsoo Kim,Hui Seung Noh,Hung Soo Kim 한국방재학회 2016 Journal of Disaster Management Vol.1 No.4
Rainfall has recently begun to show different properties in space and time. In particular, although localized heavy rainfall is frequent, rain gauges on the ground can only observe rainfall at one point. In other words, ground-based rain gauges have limitations in spatial and temporal resolution for measuring rainfall. As a result, there is a need to utilize radar rainfall measurements that can consider the spatial distribution of the change in rainfall based on the direction of the storm. In this study, we tried to apply radar rainfall for a runoff simulation of an urban drainage system. The study area was Guro-gu, Seoul City, Korea, and we divided the study area into sub-basins based on the rain gauge network of the AWS (Automatic Weather Station). Then, the radar rainfall data were adjusted using the rainfall data of the rain gauge stations, and the areal rainfall amounts were obtained. The runoffs were simulated using the XP-SWMM model in the sub-basins of an urban drainage system. As a result, the adjusted radar rainfalls underestimated the ground-based measurement data by 60 to 95%. Therefore, differences in runoffs simulated by the adjusted radar and the gauge rainfall amounts are found. The peak runoff time from the radar rainfall occurred earlier than that from the gauge rainfall. This result is due to the fact that the radar rainfall can reflect the spatial variability of the rainfall in time by taking into consideration the movement of a storm.
Low cost FMCW radar systems with the reduced number of FFT points under indoor environments
Kim, Narae,Kim, Seunghyun,Park, Hyobeen,Jung, Yunho,Lee, Seongjoo Informa UK (TaylorFrancis) 2018 Journal of electromagnetic waves and applications Vol.32 No.13
<P>In this paper proposed is a cost-efficient signal processing algorithm of a frequency modulation continuous wave (FMCW) radar for the close range under indoor environments. Recently, the use of an FMCW radar has been expanded to short distance from long distance due to easy production and inexpensive designing costs. In order to obtain satisfying resolution of the close range radar, it still requires a wide modulation bandwidth, which results in high costing wideband RF devices. This paper proposes a cost-efficient signal processing method using correlations between a reflected signal in frequency-domain and a lookup table which holds the frequency information depending on distances. The proposed algorithm shows the similar performance to a wideband system just by updating a firmware of low costing narrowband RF FMCW radar devices without additional hardware modification.</P>
Survival and pattern of Recurrence in Bevacizumab for advanced cervical cancer
( Nara Lee ),( Seik Kim ),( Jaehyun Cho ),( Maria Lee ),( Hee Seung Kim ),( Hyun Hoon Chung ),( Jae Weon Kim ),( Noh Hyun Park ),( Yong Sang Song ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-
Objective: To evaluate the efficacy and pattern of recurrence of bevacizumab and chemotherapy in persistent, recurrent, or metastatic cervical cancer. Methods: We retrospectively reviewed medical records of 1) patients with persistent, recurrent, or metastatic cervical cancer treated at SNUH from 2014.4 to 2018.2 and 2) all patients for treatment with cisplatin plus paclitaxel and bevacizumab every 3 weeks until disease progression or unacceptable toxic effect or complete response. Results: Of 57 patients, 36 (63%) patients had recurrent disease, 7(12.3%) patients had persistent and 14 (24.6%) had metastatic disease at treatment. The prior exposition to platinum was 29 (50.9%). Grade 3 or 4 adverse events possibly related to bevacizumab included hypertension (n= 3, 5.3%), febrile neutropenia (n= 4, 7%), or fistula (n=1, 1.8%). During follow-up, there were 21 deaths(36.8%) and 24 recurrence (42.1%) (distant n=10, 41.7%, locoregional n=13, 54.2%, or peritoneal seeding n=5, 20.8%), nodal(n=10, 41.7%). The median PFS and OS were 6.64 and 18.20 months, respectively. Conclusion: This study can provide useful information about clinical efficacy and recurrence pattern of bevacizumab combined with chemotherapy about patients with recurrent, persistent or metastatic cervical cancer.
( Nara Kim ),( Yong-kweon Kim ) 융합연구학회 2019 융합연구학회지 Vol.3 No.2
The purpose of this study was to determine the frequency with which exercise specialist address certain psychological issues related to injury and non-injury related psychological issues with their athletes or patients, their attitude to deal with psychological issues, and referral patterns to other mental health professionals. A hundred clinical exercise specialists who educate exercise rehabilitation of the injured athletes were participated and data from 60 persons were analyzed. Statistical analyses were performed using SPSS (version 18.0 for windows). Exercise specialist (ES) group reported frequently encountering psychological issues more related to injury than unrelated to injury in athletes and patients. Furthermore, ES believed it was their role to address injury more than non-injury-related psychological issues with athletes and patients. Less experienced ES reported slightly less competent and much less comfortable with psychological skills than more experienced ES. The current findings suggest that ES encounter and discuss psychological issues during rehabilitation frequently. Clinical implications regarding the dealing with psychological issues during the rehabilitation were discussed.
Narae Han,Jiwoong Wi,Sungoh Im,Ka-Min Lim,Hun-Dong Lee,Won-Joong Jeong,Geun-Joong Kim,Chan Song Kim,Eun-Jeong Park,Mi Sook Hwang,최동욱 한국조류학회I 2021 ALGAE Vol.36 No.3
An increase in seawater temperature owing to global warming is expected to substantially limit the growth of marine algae, including Pyropia yezoensis, a commercially valuable red alga. To improve our knowledge of the genes involved in the acquisition of heat tolerance in P. yezoensis, transcriptomes sequences were obtained from both the wild-type SG104 P. yezoensis and heat-tolerant mutant Gy500. We selected 1,251 differentially expressed genes that were up- or downregulated in response to the heat stress condition and in the heat-tolerant mutant Gy500, based on fragment per million reads expression values. Among them, PyHRG1 was downregulated under heat stress in SG104 and expressed at a low level in Gy500. PyHRG1 encodes a secretory protein of 26.5 kDa. PyHRG1 shows no significant sequence homology with any known genes deposited in public databases to date. However, PyHRG1 homologs were found in other red algae, including other Pyropia species. When PyHRG1 was introduced into the single-cell green alga Chlamydomonas reinhardtii, transformed cells overexpressing PyHRG1 showed severely retarded growth. These results demonstrate that PyHRG1 encodes a novel red algae-specific protein and plays a role in heat tolerance in algae. The transcriptome sequences obtained in this study, which include PyHRG1, will facilitate future studies to understand the molecular mechanisms involved in heat tolerance in red algae.
NaRae Han,Jongkee Kim 한국육종학회 2014 한국육종학회 심포지엄 Vol.2014 No.07
Glucosinolates (GLS) are secondary metabolites commonly occurring in Brassica crops and more than 130 different GLS have been reported in diverse plants. Recent studies have indicated that isothiocyanate (ITC) derived from GLS by hydrolysis had a potential for anticancer activity against several rumor cells on human. In addition, it was found that glucoraphenin (GRE) and glucoraphasatin (GRH) were abundant and differently regulated in radish plant, depending upon organs and developmental stages. Microspores isolated from flower buds of radish were cultured in vitro to obtain doubled haploid (DH; but homozygous) lines in a short time period. The present study was conducted to determine the concentration of GRE and GRH, an immediate precursor of ITC from DH lines of radish plant. Total 41 DH lines were selected based on flow cytometry analysis. The seeds, obtained by bud pollination from the DH lines, were planted and 3-weeks-old young seedlings were used for the major aliphatic GLS analysis. Amounts of GRH were highly variable from the DH lines ranging from 2.3 to 31.5 mg·g-1 dry weight (DW). The donor plant (DP) contained 18.4 mg·g-1 DW. It was noticed that there were 6-fold differences in the amounts of GRE between the highest and lowest DH lines. Among 41 lines tested, 14 DH lines of radish plant were significantly reduced in the amount of sum of GRH and GRE compared those of the donor plant (P<0.05), whereas only three lines increased. The results obtained in the present study will lend to select genotypes with low and high GLS contents of radish plant. In addition, those DH lines will aid to elucidate a biosynthetic pathway of the aliphatic GLS in radish plant, which remain for the most part unsolved.