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( Ming Yi Zhao ),( Ming Hua Yang ),( Liang Chun Yang ),( Yan Yu ),( Min Xie ),( Shan Zhu ),( Rui Kang ),( Dao Lin Tang ),( Zhi Gang Jiang ),( Wu Zhou Yuan ),( Xiu Shan Wu ),( Li Zhi Cao ) 생화학분자생물학회(구 한국생화학분자생물학회) 2011 BMB Reports Vol.44 No.9
HMGB1 is associated with human cancers and is an activator of autophagy which mediates chemotherapy resistance. We here show that the mRNA levels of HMGB1 are high in leukemia cells and it is involved in the progression of childhood chronic myeloid leukemia (CML). HMGB1 decreases the sensitivity of human myeloid leukemia cells K562 to anti-cancer drug induced death through up-regulating the autophagy pathway, which is confirmed by the observation with an increase in fusion of autophagosomes and autophagolysosomes. When overexpressing HMGB1, both mRNA levels of Beclin-1, VSP34 and UVRAG which are key genes involved in mammalian autophagy and protein levels of p-Bcl-2 and LC3-II are increased. Luciferase assays document that over-expression of HMGB1 increases the transcriptional activity of JNK and ERK, which may be silenced by siRNA. The results suggest that HMGB1 regulates JNK and ERK required for autophagy, which provides a potential drug target for therapeutic interventions in childhood CML. [BMB reports 2011; 44(9): 601-606]
Study of the H2O/Al2O3 Interface and the Acting Mechanism of Water in the Working Electrolyte
Ming Jia,Qiang Li,Lixiang Li,Liang Cao,Juan Yang,Xiang-Yang Zhou,Liang Ai 대한금속·재료학회 2018 ELECTRONIC MATERIALS LETTERS Vol.14 No.5
Using a working electrolyte containing mixed solvents of ethylene glycol and N,N-dimethylformamide, this paper presentsa study of the reactions on the H2O/Al2O3 interface with sum frequency vibrational spectroscopy and the effects of differentwater content on the performance of the working electrolyte and an aluminum electrolytic capacitor and summarizes the rulesof the variations in the performance parameters of the working electrolyte and aluminum electrolytic capacitor with respect tothe water content. The results demonstrate that, when the water content is increased from 2.5 to 15%, the conductivity of theworking electrolyte increased by 930 μS/cm, and the sparking voltage decreased by 27 V. Also, the increased water contentcauses lower oxidation efficiency and lower thermal stability. The leakage current of the aluminum electrolytic capacitorafter high-temperature storage increases with an increase in the water content, and the attenuation rate of capacitor’s thelow-temperature capacitance decreases with an increase in the water content.
Yang Liu,Guanyu Hu,Lei Cao,Xiaojing Wang,Ming-Hui Chen 한국통계학회 2019 Journal of the Korean Statistical Society Vol.48 No.4
Nowadays, Bayesian methods are routinely used for estimating parameters of item response theory (IRT) models. However, the marginal likelihoods are still rarely used for comparing IRT models due to their complexity and a relatively high dimension of the model parameters. In this paper, we review Monte Carlo (MC) methods developed in the literature in recent years and provide a detailed development of how these methods are applied to the IRT models. In particular, we focus on the ‘‘best possible’’ implementation of these MC methods for the IRT models. These MC methods are used to compute the marginal likelihoods under the one-parameter IRT model with the logistic link (1PL model) and the two-parameter logistic IRT model (2PL model) for a real English Examination dataset. We further use the widely applicable information criterion (WAIC) and deviance information criterion (DIC) to compare the 1PL model and the 2PL model. The 2PL model is favored by all of these three Bayesian model comparison criteria for the English Examination data.
Study on Crystallization Kinetics of Dynamically-Vulcanized PP/EPDM Blends
Bin Yang,Yan-Li Deng,Xia Ru,Ji-Bin Miao,Ming Cao,Jia-Sheng Qian,Li-Fen Su,Peng Chen,Jing-Wang Liu,La-Xia Wu,Tao Pang 한국고분자학회 2016 폴리머 Vol.40 No.4
Two types of β nucleating agents (β-NAs), aryl dicarboxylic acid amide (TMB-5) and diphenyl phthalate diamine (NT-C), were adopted to modify the polypropylene (PP)/ethylene propylene diene monomer (EPDM) blends, which were prepared by dynamic-vulcanization technology. Wide angle X-ray diffraction (WAXD) and differential scanning calorimetry (DSC) were used to study the crystallization kinetics of PP. Our results showed that the addition of β-NAs can considerably increase the crystallization temperature, and significantly decrease the spherulite size of β-PP (L300). The Jeziorny analysis showed there were ~82% and ~89% of relative crystallinity generated from the primary crystallization in the composites containing TMB-5 and NT-C, respectively. The crystallization half time (t0.5) showed that NT-C improved the overall crystallization rate more effectively than TMB-5. In addition, the peaks of the relative crystallization rate curves were shifted towards higher temperature by 14 and 9℃ with the addition of TMB-5 and NT-C, respectively.
Design and analysis of integrated-circuit package antenna (ICPA) for dual-band wireless transceivers
Tong, Ming-Sze,Yang, Mingwu,Cao, Qunsheng,Kim, Hyeong-Seok,Lu, Yilong,Chen, Yinchao,Chang, Tae-Gyu Wiley Subscription Services, Inc., A Wiley Company 2006 International journal of RF and microwave computer Vol.16 No.3
<P>This article presents study of a dual-band integrated-circuit package antenna (ICPA), which operates concurrently on dual bands at 2.4 and 5.25 GHz. The antenna is designed and printed on the top surface of an IC package and fed by a single coaxial line, while the transceiver is implemented on the opposite side of the package, through the separation of a common ground plate. This “cavity-down” arrangement minimizes the electromagnetic interference between the antenna and transceiver, and satisfies the miniaturization of the design. The study consists of numerical computations, which are performed through an in-house computer solver based on the nonuniform finite-difference time-domain (NU-FDTD) method and experimental measurements. Together with the data computed using the high-frequency structure simulator (HFSS) software, the results show excellent agreement between the numerical and experimental data, and the proposed structure is deemed as a useful application in the area of highly integrated wireless transceivers. © 2006 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2006.</P>
Hong Yang,Cao Zhou,Dao-chao Jin,Ming-fu Gong,Zhao Wang,Gui-yun Long 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.4
The brown planthopper Nilaparvata lugens negatively affects rice yield by sucking nutrients from the rice stem and spreading viruses. In this study, the effects of sublethal concentrations of abamectin on development, fecundity, and wing morphs of N. lugens were investigated. Treatment with sublethal concentrations of abamectin showed no significant effects on the developmental period of F 0 nymphs. Although LC 10 and LC 25 treatments resulted in 10% and 25% mortality, the LC 25 treatment significantly prolonged the lifespan of macropterous and brachypterous females. Abamectin-treated brachypterous females showed significantly lower fecundity than control females. Furthermore, abamectin treatment showed no significant effects on the developmental period of F 1 nymphs. However, LC 25 treatment significantly inhibited the fecundity of brachypterous F 1 females and significantly reduced the proportion of macropterous F 1 females and brachypterous F 1 males. LC 25 treatment showed no significant effects on the fecundity of macropterous F 1 females. Considering the proportion of macropterous and brachypterous F 1 females, the relative fitness of the macropterous F 1 nymphs in the control, LC 10 , and LC 25 treatment groups was 1, 1.02, and 0.84, respectively, and that of brachypterous F 1 nymphs was 1, 0.79, and 0.93, respectively. Sublethal concentrations of abamectin inhibited N. lugens emergence. The present findings indicate the potential of abamectin for N. lugens field control.
Effect of Microstructure on Thermal Conductivity of Polymer Composites
Yue Yang,Junjie Shu,Peng Chen,Ru Xia,Jiasheng Qian,Bin Yang,JIBIN MIAO,LIFEN SU,Zhengzhi Zheng,Ming Cao 한국고분자학회 2017 Macromolecular Research Vol.25 No.4
Thermal conductivity (TC) of polymer composites is strongly depended on thermal conductive fillers as well as heat conduction pathways formed by these fillers. In this work, we examined effects of morphology, size and arrangement of fillers on TC of polymer composites by using energy-conserving dissipative particle dynamic (e-DPD) simulation. Theoretically, we explored effects of ideal and “pseudo” thermal conductive pathways on composites’ TC and investigated heat conduction of filler particles with cubic-center and lamellar morphology. To confirm orientation and size effects of lamellar filler particles on composites’ TC, we prepared a series of Boron Nitride/Silicon rubber composites (BN/SiR). Being same with those observed in e-DPD simulation, orientation could efficiently improve TC of BN/SiR composites. The TC of composites with filled diameters about 10 micrometer of BN flats is 11 times higher than that of SiR matrix. Our researching results show that heat conduction pathways are essential to transportation of heat flux in polymer composites and even “pseudo” pathways by disconnected filler particles along temperature gradient can accelerate heat conduction.