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      • SCIESCOPUS

        Hybrid displacement FE formulations including a hole

        Leconte, Nicolas,Langrand, Bertrand,Markiewicz, Eric Techno-Press 2009 Structural Engineering and Mechanics, An Int'l Jou Vol.31 No.4

        The paper deals with the problem related to the modelling of riveted assemblies for crashworthiness analysis of full-scale complete aircraft structures. Comparisons between experiments and standard FE computations on high-energy accidental situations onto aluminium riveted panels show that macroscopic plastic strains are not sufficiently localised in the FE shells connected to rivet elements. The main reason is related to the structural embrittlement caused by holes, which are currently not modelled. Consequently, standard displacement FE models do not succeed in initialising and propagating the rupture in sheet metal plates and along rivet rows as observed in the experiments. However, the literature survey show that it is possible to formulate super-elements featuring defects that both give accurate singular strain fields and are compatible with standard displacement finite elements. These super-elements can be related to the displacement model of the hybrid-Trefftz principle of the finite element method, which is a kind of domain decomposition method. A feature of hybrid-Trefftz finite elements is that they are mainly used for elastic computations. It is thus proposed to investigate the possibility of formulating a hybrid displacement finite element, including the effects of a hole, dedicated to crashworthiness analysis of full-scale aeronautic structures.

      • SCIESCOPUSKCI등재
      • KCI등재

        Cell Viability of Normal Human Skin Fibroblast and Fibroblasts Derived from Granulation Tissue: Effects of Nutraceuticals

        M.H. Borawska,S.K. Czechowska,R. Markiewicz,A. Hayirli,E. Olszewska,K. Sahin 한국식품영양과학회 2009 Journal of medicinal food Vol.12 No.2

        The effects of lycopene, genistein, and epigallocatechin-3-gallate (EGCG) on cell viability were tested in vitro using a normal human skin fibroblast (NHSF) cell line (CRL-1474) and granulation tissue fibroblasts (GTFs) obtained from a patient with middle ear cholesteatoma. Cell cultures were added with lycopene (1, 5, and 10 μM), genistein (1, 5, 10, 25, and 50 μM), and EGCG (1, 5, 10, 25, and 50 μM) and their respective control cultures were established by adding 5 mL/L tetrahydrofuran (THF), 5 mL/L dimethyl sulfoxide (DMSO), and 5 mL/L DMSO. A colorimetric assay was employed for determining cell viability using thiazolyl blue tetrazolium bromide. Cell viability was expressed as a percentage of the control. Data were analyzed using two-way analysis of variance separately for each compound. Lycopene addition decreased viability of NHSFs and GTFs compared with THF addition (64.1%, 60.5%, and 100%, respectively, P < .0001). Genistein addition also increased viability of both NHSFs and GTFs compared with DMSO addition (P < .02). Increasing EGCG concentration tended to cause a linear increase in viability of NHSFs but did not alter viability of GTFs (P < .10). Our data suggest that genistein and EGCG but not lycopene could help maintaining or improving skin health through enhancing viability of skin fibroblasts.

      • KCI등재

        Cell Viability of Normal Human Skin Fibroblast and Fibroblasts Derived from Granulation Tissue: Effects of Nutraceuticals

        Borawska, M.H.,Czechowska, S.K.,Markiewicz, R.,Hayirli, A.,Olszewska, E.,Kazim Sahin, D.V.M The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.2

        The effects of lycopene, genistein, and epigallocatechin-3-gallate (EGCG) on cell viability were tested in vitro using a normal human skin fibroblast (NHSF) cell line (CRL-1474) and granulation tissue fibroblasts (GTFs) obtained from a patient with middle ear cholesteatoma. Cell cultures were added with lycopene (1, 5, and $10\;{\mu}M$), genistein (1, 5, 10, 25, and $50\;{\mu}M$), and EGCG (1, 5, 10, 25, and $50\;{\mu}M$) and their respective control cultures were established by adding 5 mL/L tetrahydrofuran (THF), 5 mL/L dimethyl sulfoxide (DMSO), and 5 mL/L DMSO. A colorimetric assay was employed for determining cell viability using thiazolyl blue tetrazolium bromide. Cell viability was expressed as a percentage of the control. Data were analyzed using two-way analysis of variance separately for each compound. Lycopene addition decreased viability of NHSFs and GTFs compared with THF addition (64.1%, 60.5%, and 100%, respectively, P < .0001). Genistein addition also increased viability of both NHSFs and GTFs compared with DMSO addition (P < .02). Increasing EGCG concentration tended to cause a linear increase in viability of NHSFs but did not alter viability of GTFs (P < .10). Our data suggest that genistein and EGCG but not lycopene could help maintaining or improving skin health through enhancing viability of skin fibroblasts.

      • KCI등재

        Hybrid displacement FE formulations including a hole

        Nicolas Leconte,Bertrand Langrand,Eric Markiewicz 국제구조공학회 2009 Structural Engineering and Mechanics, An Int'l Jou Vol.31 No.4

        The paper deals with the problem related to the modelling of riveted assemblies for crashworthiness analysis of full-scale complete aircraft structures. Comparisons between experiments and standard FE computations on high-energy accidental situations onto aluminium riveted panels show that macroscopic plastic strains are not sufficiently localised in the FE shells connected to rivet elements. The main reason is related to the structural embrittlement caused by holes, which are currently not modelled. Consequently, standard displacement FE models do not succeed in initialising and propagating the rupture in sheet metal plates and along rivet rows as observed in the experiments. However, the literature survey show that it is possible to formulate super-elements featuring defects that both give accurate singular strain fields and are compatible with standard displacement finite elements. These super-elements can be related to the displacement model of the hybrid-Trefftz principle of the finite element method, which is a kind of domain decomposition method. A feature of hybrid-Trefftz finite elements is that they are mainly used for elastic computations. It is thus proposed to investigate the possibility of formulating a hybrid displacement finite element, including the effects of a hole, dedicated to crashworthiness analysis of fullscale aeronautic structures.

      • KCI등재

        Meat Quality of Crossbred Porkers without the Gene RYR1T Depending on Slaughter Weight

        Grazyna Czyzak-Runowska,Janusz Wojtczak,Andrzej Lyczynski,Jacek Wojtowski,Maria Markiewicz-Keszycka,Daniel Stanislawski,Marek Babicz 아세아·태평양축산학회 2015 Animal Bioscience Vol.28 No.3

        The first aim of the study was to compare selected meat quality parameters in porkers without the gene RYR1T (ryanodine receptor gene). These were porkers slaughtered at 100 to 115 kg and 116 to 130 kg live weight. The second aim of the study was to determine the occurrence frequency of standard-quality meat (red, firm, nonexudative [RFN]) and the occurence frequency of defective meat (pale, soft, exudative [PSE] and acid, soft, exudative [ASE]). The analysis was conducted on the longissimus lumborum muscle in 114 crossbred porkers. The porkers were a cross of Camborough 22 sows and boars from lines 337PIC (Pig Improvement Company), Norsvin Landrace and Pietrain. All of the animals were provided with identical environmental and nutritional conditions. The average weight of the slaughtered animals in the light and heavy groups was 110 kg and 122 kg, respectively. Both groups had the same average post-slaughter meatiness (56.5%). A statistical analysis of selected meat-quality parameters did not show any significant differences between the weight groups. On the other hand, the classification based on carcass quality showed an occurence frequency of defective meat in heavier crossbred porkers (116 to 130 kg) that was three times higher than in those crossbred animals which weighed 100 to 115 kg when slaughtered. In porkers without the gene RYR1T, the defective meat types PSE and ASE occurred with a frequency of 17.54%.

      • SCIESCOPUSKCI등재

        Meat Quality of Crossbred Porkers without the Gene RYR1<sup>T</sup> Depending on Slaughter Weight

        Czyzak-Runowska, Grazyna,Wojtczak, Janusz,Lyczynski, Andrzej,Wojtowski, Jacek,Markiewicz-Keszycka, Maria,Stanislawski, Daniel,Babicz, Marek Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.3

        The first aim of the study was to compare selected meat quality parameters in porkers without the gene $RYR1^T$ (ryanodine receptor gene). These were porkers slaughtered at 100 to 115 kg and 116 to 130 kg live weight. The second aim of the study was to determine the occurrence frequency of standard-quality meat (red, firm, nonexudative [RFN]) and the occurence frequency of defective meat (pale, soft, exudative [PSE] and acid, soft, exudative [ASE]). The analysis was conducted on the longissimus lumborum muscle in 114 crossbred porkers. The porkers were a cross of Camborough 22 sows and boars from lines 337PIC (Pig Improvement Company), Norsvin Landrace and Pietrain. All of the animals were provided with identical environmental and nutritional conditions. The average weight of the slaughtered animals in the light and heavy groups was 110 kg and 122 kg, respectively. Both groups had the same average post-slaughter meatiness (56.5%). A statistical analysis of selected meat-quality parameters did not show any significant differences between the weight groups. On the other hand, the classification based on carcass quality showed an occurence frequency of defective meat in heavier crossbred porkers (116 to 130 kg) that was three times higher than in those cross bred animals which weighed 100 to 115 kg when slaughtered. In porkers without the gene $RYR1^T$, the defective meat types PSE and ASE occurred with a frequency of 17.54%.

      • Closed-Loop Cryogenic Cooling for a 21 T FT-ICR Magnet System

        Choi, Y.S.,Kim, D.L.,Painter, T.A.,Markiewicz, W.D.,Lee, B.S.,Yang, H.S.,Yoo, J.S. IEEE 2008 IEEE transactions on applied superconductivity Vol.18 No.2

        <P>A closed-loop cooling concept for 21 T Fourier transform ion cyclotron resonance (FT-ICR) superconducting magnets is presented. In the magnet system, low temperature superconducting coils are immersed in a subcooled 1.8 K bath, which is connected to the saturated helium reservoir through the weight load relief valve. Saturated liquid helium is refrigerated by a Joule-Thomson (JT) heat exchanger and flows through the JT valve, isenthalpically dropping its pressure to approximately 1.6 kPa, corresponding to a saturation temperature of 1.8 K. Helium gas exhausted from JT pump is liquefied by a two-stage cryocooler located after the vapor purify system. In the present paper, the amount of heat budget is determined and the structural design of cryostat is carried out by the relevant analyses. The position of a cryocooler in the magnet system is investigated, taking into account the requirement of magnetic field for normal performance. Helium liquefaction system, a key component of the closed-loop cooling system, is fabricated and tested in order to demonstrate the feasibility of our new cryogenic cooling for high field magnets.</P>

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