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A Novel Design of Suspension System for Driver's Seat
Thanh-Tung Luu(Thanh-Tung Luu),박성태(Sung-Tae Park) 한국자동차공학회 2005 한국자동차공학회 춘 추계 학술대회 논문집 Vol.2005 No.5_2
A driver's seat can be modeled with a suspension system of spring, mass and damper. To increase the capacity of anti-vibration, the natural frequency should be decreased as low as possible. In this paper, the method to decrease the natural frequency by the potential energy is introduced. In addition, the experiment is done on a small model to prove the theorem.
Duy Tran Luu,Truong Vinh Tran Luu 아시아기술혁신학회 2023 Asian Journal of Innovation and Policy Vol.12 No.2
This paper employs datasets from the Enterprise Survey conducted by the World Bank to examine the relationship between four types of innovation defined by the Oslo Manual (OECD, 2005): product innovation, process innovation, marketing innovation, organization innovation, and the firm performance in the selected developing ASEAN economies. The main objective of this paper is to understand the characteristics of innovation activities at the firm level and how various innovation types affect firm performance. The empirical results from ASEAN manufacturing firms reveal that product innovation positively affects firms’ performance, while non-technological innovations are negatively related to the performance of firms. The further employed quantile regression provides more insights into the roles of innovation types on different levels of firm performance: while product and process innovations actively contribute to the small and medium-size firms (below 25th quantile and median), organizational and marketing innovations negatively affect them. Interestingly, the role of process innovation decreases when firm performance grows.
Luu, Quynh-Phuong,Shin, Ji-Young,Kim, You-Kyoung,Islam, Mohammad Ariful,Kang, Sang-Kee,Cho, Myung-Haing,Choi, Yun-Jaie,Cho, Chong-Su American Chemical Society 2012 MOLECULAR PHARMACEUTICS Vol.9 No.8
<P>Cationic polymers have been the subject of intense research as nonviral gene delivery systems due to several advantages in comparison with viral vectors. However, the nonsimultaneous combination of high transfection efficiency and low cytotoxicity of nonviral vectors for gene delivery has long been an issue for scientists looking into ways to deliver genes into cells. Toward this goal, we designed, synthesized, and evaluated a safe and accelerated gene transfer system through polysorbitol-mediated transporter (PSMT) based on sorbitol diacrylate (SDA) and low molecular weight polyethylenimine (LMW PEI). The PSMT formed stable complexes with plasmid DNA in serum. The nano sizes and spherical shapes of PSMT/DNA complexes are not toxic, even at a high concentration of PSMT. The higher transfection efficiency of PSMT compared to PEI 25K was observed both <I>in vitro,</I> despite the existence of many hydroxyl groups, and <I>in vivo</I>. These improvements presumably stem from the osmotic property of polysorbitol and endosomal buffer capacity of PEI in PSMT. Most importantly, we confirmed that the selective cavaeolae endocytic pathway played a role in high transfection efficiency by osmotic PSMT-mediated gene delivery. We propose that PSMT is a promising nonviral carrier for the effective gene delivery to cancer cells via synergistic effects derived from rapid cellular uptake through the caveolae endocytic pathway and a high endosomal buffering capacity.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/mpohbp/2012/mpohbp.2012.9.issue-8/mp300072r/production/images/medium/mp-2012-00072r_0012.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/mp300072r'>ACS Electronic Supporting Info</A></P>