성서의 주인공은 “지극히 작은자”

Luise Schottroff,정보영(번역자) 한국여신학자협의회 1992 한국여성신학 Vol.- No.11

Zum Begriff der Mitte

Luise Rinser 한국독어교육학회 1976 독어독문학 Vol.- No.7

Hermann Hesses Demian in der südkoreanischen Populärkultur

( Viktoria Luise Döberl ) 한국헤세학회 2018 헤세연구 Vol.40 No.-

Adored by the readers, abhorred by the critics – Hermann Hesse has a controversial position in the literary landscape. Although the enthusiasm among Western readers has decreased during the last decades, the affinity for Hesse’s works is still very present in East Asia – especially in modern South Korea, where Hesse’s Demian serves as a basis for a product of its inscrutable, flourishing Pop-Culture, boasting in prosperousness that unfolds far beyond South Korea’s borders. The article tries to examine this phenomenon in the aspect of Postcolonialism and Hyperkulturalität. Von den Leser*innen weltweit geliebt, von der deutschsprachigen Literaturkritik bekrittelt – Hermann Hesse nimmt eine brisante Position in der Literaturlandschaft ein. Obgleich der Enthusiasmus der westlichen Hesse Leser*innen in den letzten Jahrzehnten etwas nachgelassen hat, ist die Affinität für seine Werke in Ostasien hervorstechend – besonders im modernen Südkorea, indem Hesses Demian als Basis für ein Produkt dessen undurchschaubarer, florierender Populärkultur ebnet, welche weit über die Landesgrenzen hinaus Erfolge feiert. Der vorliegende Artikel versucht dieses Phänomen unter den Aspekten des Postkolonialismus und der Hyerpkulutralität zu untersuchen.

Advances in Signal Processing for GNSSs [From the Guest Editors]

Closas, Pau,Luise, Marco,Avila-Rodriguez, Jose-Angel,Hegarty, Christopher,Lee, Jiyun IEEE 2017 IEEE signal processing magazine Vol.34 No.5

<P>Examines global navigation satellite systems (GNSS). The papers in this special issue address the design of special GNSS signals, a topic of particular interest in the past and still of great relevance today. It continues with the discussion of effective techniques for receiver performance enhancement and finishes with the analysis of some vulnerabilities. GNSS technology today is ubiquitous in many transversal infrastructures and has become the backbone of all applications where precise position, navigation, and timing (PNT) of user equipment is required. Moreover, GNSS is the pervasive PNT technology in outdoor environments, where its performance, coverage, and reliability exceeds that of other technical solutions.</P>

Auto-induction Screening Protocol for Ranking Clonal Libraries of Pichia pastoris MutS Strains

David Wollborn,Rebecca Luise Müller,Lara Pauline Munkler,Rebekka Horstmann,Andrea Germer,Lars Mathias Blank,Jochen Büchs 한국생물공학회 2022 Biotechnology and Bioprocess Engineering Vol.27 No.4

Screening Pichia pastoris (Komagataella phaffii) strain libraries utilizing the methanol inducible alcohol oxidase 1 (AOX1) promoter requires addition of methanol as an inducer during cultivation. As the AOX1 promoter is repressed in the presence of glucose or glycerol, common screening procedures include long incubation times before methanol induction by successive multiple additions. In this study, a P. pastoris MutS strain, secreting a green fluorescent protein (GFP), was used to characterize a standard screening protocol in complex medium. Based on these results, an auto-induction screening method for P. pastoris strains was developed using mineral SYN6 medium, where methanol was added from the beginning. To gain more insight into growth and production behavior, the cultures were online-monitored, using the Respiration Activity Monitoring System and the BioLector system. Monitoring the oxygen transfer rate indicated that prolonged cultivation phases before induction can be avoided and that high glucose concentrations hinder inducible protein production. The results show the effects of using 20 g/L glucose, and the resulting ethanol formation on the screening process. The newly developed auto-induction method was then used to screen and rank a strain library of high, medium, and low GFP producers. These results demonstrate that the auto-induction method facilitates the identification of high producers during primary screening. It is significantly less time consuming and labor intensive. Nonetheless, it leads to the same conclusion as the conventional screening with manual methanol additions.

Minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient‑acceptable symptom state (PASS) in patients who have undergone total knee arthroplasty: a systematic review

( Filippo Migliorini ),( Nicola Maffulli ),( Luise Schäfer ),( Francesco Simeone ),( Andreas Bell ),( Ulf Krister Hofmann ) 대한슬관절학회 2024 대한슬관절학회지 Vol.36 No.-

Background The present systematic review investigated the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) of several frequent and established PROMs used to assess patients who have undergone TKA. This study was conducted according to the 2020 PRISMA statement. Methods In September 2023, PubMed, Web of Science, and Embase were accessed with no time constraint All clinical studies investigating tools to assess the clinical relevance of PROMs used to evaluate patients having received TKA were accessed. Only studies which evaluated the MCID, PASS, or SCB were eligible. The PROMs of interest were the Forgotten Joint Score-12 (FJS-12), the Oxford Knee Score (OKS), the Knee Injury and Osteoarthritis Outcome Score (KOOS) and its related subscales activity of daily living (ADL), pain, quality of life (QoL), sports and recreational activities, and symptoms, the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) score, the Knee Society Score (KSS) and related function score, and the Short Form-12 (SF-12) and Short Form-36 (SF-36). Results Data from 29,737 patients were collected. The overall risk of bias was low to moderate. The great variability of thresholds for MCID, SCB and PASS between questionnaires but also between investigated aspects was noted, whereby MCIDs for the SF-36 appear lower than for knee-specific questionnaires Conclusion Despite its critical role from a patient’s perspective, the dimension of SCB is still neglected in the literature. Moreover, thresholds for the different concepts need to be condition-specific. We encourage authors to specifically report such data in future studies and to adhere to previously reported definitions to allow future comparison. Level of evidence Level IV, systematic review and meta-analysis

Common Errors in the Treatment of Diabetes Mellitus

Martin, F.I.R,Higginbotham, Linda,Luise, Mario De Medical Publications Korea 1975 Medical Progress Vol.2 No.9

HPP 고압처리: 식품 안전과 유효기간에 관련한 혁신적인 기술

신진영,Shin, Jin-Young,Marraud, Jorge Luise 한국축산식품학회 2019 축산식품과학과 산업 Vol.8 No.1

Exploitation of the Dose/Time-Response Relationship for a New Measure of DNA Repair in the Single-Cell Gel Electrophoresis (Comet) Assay

Byung-Soo Kim,Lutz Edler,Jin Joo Park,Dietrich von Fournier,Wulf Haase,Marie-Luise Sautter-Bihl,Egbert Hagmuller,Florian Gotzes,Heinz Walter Thielmann 한국독성학회 2004 Toxicological Research Vol.20 No.1

The comet assay (also called the single-cell gel electrophoresis assay) has been widely used for detecting DNA damage and repair in individual cells. Since the conventional methods of evaluating comet assay data using frequency statistics are unsatisfactory we developed a new quantitative measure of DNA damage/repair that is based on all information residing in the dose/time-response curves of a comet experiment. Blood samples were taken from 25 breast cancer patients before undergoing radiotherapy. The comet assay was performed under alkaline conditions using isolated lymphocytes. Tail DNA, tail length, tail moment and tail inertia of the comet were measured for each patient at four doses of g-rays (0, 2, 4 and 8 Gy) and at four time points after irradiation (0, 10, 20 and 30 min) using 100 cells each. The resulting three-dimensional dose-time response surface was modeled by multiple regression, and the second derivative, termed 2D, on dose and time was determined. A software module was programmed in SAS/AF to compute 2D values. We applied the new method successfully to data obtained from cancer patients to be assessed for their radiation sensitivity. We computed the 2D values for the four damage measures, i.e., tail<br/> moment, tail length, tail DNA and tail inertia, and examined the pairwise correlation coefficients of 2D both on the log scale and the unlogged scale. 2D values based on tail moment and tail DNA<br/> showed a high correlation and, therefore, these two damage measures can be used interchangeably as far as DNA repair is concerned. 2D values based on tail inertia have a correlation profile different from the other 2D values which may reflect different facets of DNA damage/repair. Using the dose-time response surface, other statistical models, e.g., the proportional hazards model, become applicable for data analysis. The 2D approach can be applied to all DNA repair measures, i.e., tail moment, tail length, tail DNA and tail inertia, and appears to be superior to conventional evaluation methods as it integrates all data of the dose/time-response curves of a comet assay.

Exploitation of the Dose/Time-Response Relationship for a New Measure of DNA Repari in the Single-Cell Gel Electrophoresis (Comet) Assay

Kim, Byung-Soo,Edler, Lutz,Park, Jin-Joo,Fournier, Dietrich Von,Haase, Wulf,Sautter-Bihl, Mare-Luise,Hagmuller, Egbert,Gotzes, Florian,Thielmann, Heinz Walter Korean Society of ToxicologyKorea Environmental Mu 2004 Toxicological Research Vol.20 No.2

The comet assay (also called the single-cell gel electrophoresis assay) has been widely used for detecting DNA damage and repair in individual cells. Since the conventional methods of evaluating comet assay data using frequency statistics are unsatisfactory we developed a new quantitative measure of DNA damage/repair that is based on all information residing in the dose/time-response curves of a comet experiment. Blood samples were taken from 25 breast cancer patients before undergoing radiotherapy. The comet assay was performed under alkaline conditions using isolated lymphocytes. Tail DNA, tail length, tail moment and tail inertia of the comet were measured for each patient at four doses of $\gamma$-rays (0, 2, 4 and 8 Gy) and at four time points after irradiation (0, 10, 20 and 30 min) using 100 cells each. The resulting three-dimensional dose-time response surface was modeled by multiple regression, and the second derivative, termed 2D, on dose and time was determined. A software module was programmed in SAS/AF to compute 2D values. We applied the new method successfully to data obtained from cancer patients to be assessed for their radiation sensitivity. We computed the 2D values for the four damage measures, i.e., tail moment, tail length, tail DNA and tail inertia, and examined the pairwise correlation coefficients of 2D both on the log scale and the unlogged scale. 2D values based on tail moment and tail DNA showed a high correlation and, therefore, these two damage measures can be used interchangeably as far as DNA repair is concerned. 2D values based on tail inertia have a correlation profile different from the other 2D values which may reflect different facets of DNA damage/repair. Using the dose-time response surface, other statistical models, e.g., the proportional hazards model, become applicable for data analysis. The 2D approach can be applied to all DNA repair measures, Le., tail moment, tail length, tail DNA and tail inertia, and appears to be superior to conventional evaluation methods as it integrates all data of the dose/time-response curves of a comet assay.