Evaluation of Nutrient Release from the Matrixes Produced Based on the Shotcrete Vegetation Mulching Technique

Chia-Hsing Lee,Chia-Chen Huang,Jia-Jun Guo,Jen-Chen Fan,Dar-Yuan Lee 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Development of Graphene-based Sensors on Paper Substrate for the Measurement of pH Value of Analyte

Chia-Yi Lee,Kin Fong Lei,Shiao-Wen Tsai,Ngan-Ming Tsang 한국바이오칩학회 2016 BioChip Journal Vol.10 No.3

With excellent properties of graphene material, a number of graphene-based devices have been developed with excellent performance in the past decades. However, difficulty of processing graphene material is a hurdle for its practical realization. In this work, we propose to use vacuum filtration process as the major technique to fabricate graphene-based devices. This technique is simple and effective to practically realize graphene-based sensors on paper substrate, which are equipped with the advantages of low cost, simplicity, flexibility, and disposability. In order to show the functionality of the sensor, determination of pH value of analyte was demonstrated by direct measurement of the resistance across the sensor. Results showed that the sensor has the sensitivity of 30.8 Ω/pH and high linearity (R2=0.9282). Since graphene material can be functionalized by various molecules, it is expected that the graphene-based sensor can be further developed to realize more chemical and biological assays with high sensitivity and specificity for remote environment.

Unrecognized History of Transient Atrial Fibrillation at the Time of Discharge from an Index Stroke Hospitalization Is Associated with Increased Recurrent Stroke Risk

Chia-Yu Hsu,Daniel E. Singer,Hooman Kamel,Yi-Ling Wu,Pei-Chun Chen,Jiann-Der Lee,Meng Lee,Bruce Ovbiagele 대한뇌졸중학회 2019 Journal of stroke Vol.21 No.2

Background and Purpose Preceding episodes of paroxysmal atrial fibrillation (AF) among stroke patients can be easily overlooked in routine clinical practice. We aim to determine whether an unrecognized history of paroxysmal AF is associated with an increased risk of recurrent stroke. Methods We retrospectively identified all adult patients hospitalized with a primary diagnosis of ischemic stroke who had no AF diagnosis on their discharge records, using the Taiwan National Health Insurance Research Database between January 2001 and December 2012. Patients were categorized into two groups: unrecognized AF history and no AF. Patients with unrecognized AF history were defined as having documented AF preceding the index ischemic stroke hospitalization, but not recording at the index ischemic stroke. Primary endpoint was recurrent stroke within 1 year after the index stroke. Results Among 203,489 hospitalized ischemic stroke patients without AF diagnosed at discharge, 6,731 patients (3.3%) had an unrecognized history of prior transient AF. Patients with an unrecognized AF history, comparing to those without AF, had higher adjusted risk of all recurrent stroke ([original cohort: hazard ratio (HR), 1.41; 95% confidence interval [CI], 1.30 to 1.53], [matched cohort: HR, 1.51; 95% CI, 1.37 to 1.68]) and recurrent ischemic stroke ([original cohort: HR, 1.42; 95% CI, 1.30 to 1.55], [matched cohort: HR, 1.56; 95% CI, 1.40 to 1.74]) during the 1-year follow-up period. Conclusions Unrecognized history of AF among patients discharged after an index ischemic stroke hospitalization is associated with higher recurrent stroke risk. Careful history review to uncover a paroxysmal AF history is important for ischemic stroke patients.

The Impact of Product Involvement on Reciprocal Effect in Co-branding

Lee, Chia-Lin Korean Marketing Association 2016 ASIA MARKETING JOURNAL Vol.18 No.3

Product involvement is an important factor in consumer evaluation of co-branding. However, academic discussions over this factor have largely been neglected. This paper bridges this gap and investigates how product involvement moderates the strength of the reciprocal effect on each brand partner. We validate two theory-driven propositions by using a theoretical modeling approach. Proposition 1 explains that the negative reciprocal effect on partnering brands is stronger in the scenario of higher-involved categories than in lower-involved categories. Proposition 2 argues that the positive reciprocal effect on partnering brands can be more significant in the case of lower-involved categories than in higher-involved categories. To the best of our knowledge, we are the first to explore the influence of product involvement on reciprocal effects in the scenario of a moderately-incongruent co-branding alliance.

In-situ biochar application conserves nutrients while simultaneously mitigating runoff and erosion of an Fe-oxide-enriched tropical soil

Lee, Chia-Hsing,Wang, Chung-Chi,Lin, Huan-Hsuan,Lee, Sang Soo,Tsang, Daniel C.W.,Jien, Shih-Hao,Ok, Yong Sik Elsevier 2018 The Science of the total environment Vol.619 No.-

<P><B>Abstract</B></P> <P>Climate change gives rise to rapid degradation of rural soils in sloping subtropical and tropical areas and might further threaten environmental sustainability. In this study, we conducted an integrated evaluation of the effects of wood biochar (WB) application mixed with a green waste dreg compost (GWC) on runoff quality, soil losses, and agricultural productivity for a highly weathered tropical soil. A conventional agriculture method, in which soils are treated with anionic polyacrylamide (PAM), was also conducted for comparison. The amounts of runoff and soil loss, and nutrient retention were evaluated a year after WB application. Soil fertility was also investigated through a year pot experiment with rape (<I>Brassica campestris</I> L.) cultivation. Our results showed that the WB application not only effectively increased soil pH, soil organic carbon (SOC) and exchangeable K<SUP>+</SUP> but also increased the production of rape plants. Significant reduction of runoff and the increases of inorganic nitrogen (IN) and total phosphorus (TP) were found in the WB-treated soil. Compared to the control, the co-application of WB and GWC, particularly for the WB at 4%, decreased runoff by 16.8%, soil loss by 25%, and IN loss (via runoff) by 41.8%. Meanwhile, compared to the control and PAM treatments, the co-application of WB and GWC improved soil acidity and the contents of SOC, IN, TP, and exchangeable K<SUP>+</SUP>. The co-application of WB and GWC could be an alternative agricultural strategy to obtain benefits to agricultural productivity and environmental sustainability.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Co-applying biochar and compost notably reduced runoff and soil loss by 16%–25% in a tropical soil. </LI> <LI> In-situ biochar applying increased inorganic N, available P and K by 1.5–2.5 times in slopelands. </LI> <LI> Crop productivity was enhanced by biochar applying 1.5–2 times at least in a tropical slopeland. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Examining the Impact of Co-branding Service Failures on Consumer Evaluations

Lee, Chia-Lin Korean Marketing Association 2017 ASIA MARKETING JOURNAL Vol.19 No.3

Researchers do not fully understand consumers' responses to negative co-branding events; thus, they report inconsistent evidence regarding the negative impact on the partnering brands. Our research bridges a gap in this research stream, and answers an important question: When a service failure occurs, could the two different models of consumers' brand schema change affect their negative perception of each brand partner? By using a theoretical and mathematical modeling approach, we offer two propositions. The first proposition shows that, under consumers' book-keeping cognitive process, the negative spillover effect occurs for both brands. The second proposition argues that, when the sub-typing model is assumed, it is possible that one brand suffers while the other escapes the blame for the failure. To our knowledge, this is one of the first few studies to identify circumstances in which a negative spillover effect may or may not occur to brand partners in co-branding service failures.

Folic Acid in Stroke Prevention in Countries without Mandatory Folic Acid Food Fortification: A Meta-Analysis of Randomized Controlled Trials

Chia-Yu Hsu,Shao-Wen Chiu,Keun-Sik Hong,Jeffrey L. Saver,Yi-Ling Wu,Jiann-Der Lee,Meng Lee,Bruce Ovbiagele 대한뇌졸중학회 2018 Journal of stroke Vol.20 No.1

Background and Purpose Additional folic acid (FA) treatment appears to have a neutral effect on reducing vascular risk in countries that mandate FA fortification of food (e.g., USA and Canada). However, it is uncertain whether FA therapy reduces stroke risk in countries without FA food fortification. The purpose of this study was to comprehensively evaluate the efficacy of FA therapy on stroke prevention in countries without FA food fortification. Methods PubMed, EMBASE, and clinicaltrials.gov from January 1966 to August 2016 were searched to identify relevant studies. Relative risk (RR) with 95% confidence interval (CI) was used as a measure of the association between FA supplementation and risk of stroke, after pooling data across trials in a random-effects model. Results The search identified 13 randomized controlled trials (RCTs) involving treatment with FA that had enrolled 65,812 participants, all of which stroke was reported as an outcome measure. After all 13 RCTs were pooled, FA therapy versus control was associated with a lower risk of any future stroke (RR, 0.85; 95% CI, 0.77 to 0.95). FA alone or combination of FA and minimal cyanocobalamin (≤0.05 mg/day) was associated with a lower risk of future stroke (RR, 0.75; 95% CI, 0.66 to 0.86) whereas combination of FA and cyanocobalamin (≥0.4 mg/day) was not associated with a lower risk of future stroke (RR, 0.95; 95% CI, 0.86 to 1.05). Conclusions FA supplement reduced stroke in countries without mandatory FA food fortification. The benefit was found mostly in patients receiving FA alone or combination of FA and minimal cyanocobalamin.

The Impact of Consumer Evaluation on the Cause-Related Marketing

Chia-Lin Lee 한국마케팅학회 2017 ASIA MARKETING JOURNAL Vol.19 No.1

Cause-related Marketing (CrM) has become an increasingly popular marketing approach over the past two decades. However, neither researchers nor organizations fully understand the determinants of a successful CrM partnership. This research fills thi s gap. Specifically, we employ the schema theory to explore circumstances in which the CrM alliance cannot achieve a success. We use a theoretical modeling approach to report that, when consumers’ typicality-based cognitive process is assumed, the CrM activity with the partners’ more-discrepant attribute profile cannot be evaluated favorably, but the attribute-level uncertainty about the CrM alliance is less likely to feedback to the two partners. Furthermore, we argue that, under the schema-plus-tag model, consumers may not like the CrM program with a similar attribute profile. Therefore, this CrM approach may fail. To our knowledge, we are the first to apply the schema theory to explain how a CrM alliance can achieve a success.

Calvarial Defect Healing Induced by Small Molecule Smoothened Agonist

Lee, Soonchul,Shen, Jia,Pan, Hsin Chuan,Shrestha, Swati,Asatrian, Greg,Nguyen, Alan,Meyers, Carolyn,Nguyen, Vi,Lee, Min,Soo, Chia,Ting, Kang,James, Aaron W. Mary Ann Liebert 2016 Tissue engineering. Part A Vol.22 No.23

<P>Hedgehog (Hh) signaling positively regulates both endochondral and intramembranous ossification. Use of small molecules for tissue engineering applications poses several advantages. In this study, we examined whether use of an acellular scaffold treated with the small molecule Smoothened agonist (SAG) could aid in critical-size mouse calvarial defect repair. First, we verified the pro-osteogenic effect of SAG in vitro, using primary neonatal mouse calvarial cells (NMCCs). Next, a 4mm nonhealing defect was created in the mid-parietal bone of 10-week-old CD-1 mice. The scaffold consisted of a custom-fabricated poly(lactic-co-glycolic acid) disc with hydroxyapatite coating (measuring 4mm diameterx0.5mm thickness). Treatment groups included dimethylsulfoxide control (n=6), 0.5mM SAG (n=7) or 1.0mM SAG (n=7). Evaluation was performed at 4 and 8 weeks postoperative, by a combination of high-resolution microcomputed tomography, histology (H & E, Masson's Trichrome), histomorphometry, and immunohistochemistry (BSP, OCN, VEGF). In vivo results showed that SAG treatment induced a significant and dose-dependent increase in calvarial bone healing by all radiographic parameters. Histomorphometric analysis showed an increase in all parameters of bone formation with SAG treatment, but also an increase in blood vessel number and density. In summary, SAG is a pro-osteogenic, provasculogenic stimulus when applied locally in a bone defect environment.</P>

A Stepwise Modeling of Copper Sorption onto Kaolinite and Montmorillonite in Field Ph Range as Affected by Dissolved Organic Carbon

Chia-Hsing Lee,Zueng-Sang Chen 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6