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Eun-Soon Im,Byong-Ju Lee,Ji-Hye Kwon,So-Ra In,Sang-Ok Han 한국기상학회 2012 Asia-Pacific Journal of Atmospheric Sciences Vol.48 No.1
Because of the importance of the changes in the hydrologic cycle, accurate assessment of precipitation characteristics is essential to understand the impact of climate change due to global warming. This study investigates the changes in extreme precipitation with sub-daily and daily temporal scales. For a fine-scale climate change projection focusing on the Korean peninsula (20 km),we performed the dynamical downscaling of the global climate scenario covering the period 1971-2100 (130-year) simulated by the Max-Planck-Institute global climate model, ECHAM5, using the latest version of the International Centre for Theoretical Physics (ICTP) regional climate model, RegCM3. While annual mean precipitation exhibits a pronounced interannual and interdecadal variability,with the increasing or decreasing trend repeated during a certain period, extreme precipitation with sub-daily and daily temporal scales estimated from the generalized extreme value distribution shows consistently increasing pattern. The return period of extreme precipitation is significantly reduced despite the decreased annual mean precipitation at the end of 21st century. The decreased relatively weak precipitation is responsible for the decreased total precipitation, so that the decreased total precipitation does not necessarily mean less heavy precipitation. Climate change projection based on the ECHAM5-RegCM3 model chain clearly shows the effect of global warming in increasing the intensity and frequency of extreme precipitation, even without significantly increased total precipitation, which implies an increased risk for flood hazards.
Charcot-Marie-Tooth 1A Concurrent with Schwannomas of the Spinal Cord and Median Nerve
Kwon, Joo Young,Chung, Ki Wha,Park, Eun Kyung,Park, Sun Wha,Choi, Byung-Ok The Korean Academy of Medical Sciences 2009 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.24 No.4
<P>We identified Charcot-Marie-Tooth disease type 1A (CMT1A) in a family with schwannomas in the spinal cord and median nerve. The CMT1A in this family showed an autosomal dominant pattern, like other CMT patients with <I>PMP22</I> duplication, and the family also indicated a possible genetic predisposition to schwannomas by 'mother-to-son' transmission. CMT1A is mainly caused by duplication of chromosome 17p11.2-p12 (<I>PMP22</I> gene duplication). A schwannoma is a benign encapsulated tumor originating from a Schwann cell. A case of hereditary neuropathy with liability to pressure palsies (HNPP) concurrent with schwannoma has been previously reported. Although it seems that the co-occurrence of CMT1A and schwannomas in a family would be the result of independent events, we could not completely ignore the possibility that the coincidence of two diseases might be due to a shared genetic background.</P>