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운동 종료 후의 당질·단백질·지질의 혼합물 섭취가 근 글리코겐 회복에 미치는 효과
육조영,송영주,류기성,장창현,김한수,김대경 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5
In this study 8 male athletes and 8 female athletes for matches requiring endurance were examined for the purpose of comparison and analysis on the effect of absorption of sugars and effect of absorption of sugars+protein+fats restoration of muscular glycogen after elapse of 4 hours subsequent to closing 90 minutes exercise. (Amount of energy absorbed was same). Examinees were tested with 3 kinds of performance such as CPF Performance whereby they were made to take ① sugars (0.75 g/㎏) and protein (0.1g/㎏) and fats (0.02 g/㎏) after elapse of 1 hour subsequent to long hours of exercise and CHO Performance whereby examines were made to take ② sugars (1g/㎏) alone and Performance whereby they were made to take ③ placebo (which does not contain any sugars, protein or fats). Also the examinees took meals which had same amount of energy and nitrogen during the Performance on the date prior to experiment or on the date of experiment. Women during the exercise showed significantly higher rate of oxidation of fats, basic element of energy than that of men. In CHO Performance and CPF Performance value of blood sugar and density of insulin were significantly higher in comparison with performance with placebo. At such cases there was no difference between different genders. Same kind of phenomena were confirmed with restoration of muscular glycogen. From such fact it could be observed that absorption of fats alone and absorption of sugars+protein+fats in comparison with absorption of placebo after exercise promoted relatively higher level of restoration of muscular glycogen for both men and women.
코쉬섬 1차 반복 형태의 마이크로스트립 패치 안테나에 관한 연구
김일권,유태훈,육종관,박한규 연세대학교 전파통신연구소 2001 電波通信論文誌 Vol.5 No.1
In this paper, the microstrip patch antenna applying the koch island fractal geometry is introduced in order to reduce the antenna patch size. By space-filling property of fractal geometry, the microstrip patch applying koch island has low frequency compared with square patch antenna. In the case of 1st order iteration patchs are investigated by simulator and experiment. Through this, it is found that as the fractal iteration factor increase, the resonant frequency of koch island patch is lower. therefore koch island patch antenna can reduce patch size compared with square patch antenna. and The fabricated patch antenna is matched by using quarter wave length impedance transformer and return loss and radiation patterns are measured. The measurement result shows that the copolarization pattern of koch patch is similar to that of square patch. The cross polarization power level is -15∼-20dB.
프로와 아마추어 씨름선수들의 경쟁상태 및 특성불안에 관한 연구
이한우,육동원,고의석,김경수 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.1
The purpose of this study was to investigate differences of competition state anxiety (somatic state anxiety, cognitive state anxiety, and state self-confidence) and competition trait anxiety among three groups(highschool, university, and professional Korean Ssireum Players), and between winners and non-winners to analyze and evaluate the state of competition anxiety felt by players. Further more, This study present some useful guiding principles of effective coaching to improve the performance ability and control the competition anxiety of Ssireum players at fields. A total of 487 Ssireum players(204 highschool players, 206 college players and 77 professional players) participated in the SCAT and the CSAI-2 competition anxiety tests. Data were analyzed with One-way ANOVA and T-test. Results were as followings : College players showed significantly lower competition trait anxiety than highschool and professional players. Winner-group showed significantly lower competition trait anxiety than non-winner group. The three groups showed no statistically meaningful differences in the somatic and the cognitive state anxiety, but professional players showed significantly higher state self-confidence than highschool players. There were no differences in somatic state anxiety between winner group and non-winner group, but winner group showed significantly lower cognitive state anxiety and higher state self-confidence than non-winner group.
An effect of thermo-stimulation of lower abdomen on autonomic nervous system: An experimental study
Kim, Kyeong Han,Kim, Jong Uk,Kim, Bo Hyun,Shin, Jin Hyeon,Hong, Seong Jin,Lee, Sang Ryong,Yook, Tae-han KOREAN PHARMACOPUNCTURE INSTITUTE 2018 Journal of pharmacopuncture Vol.21 No.2
Objective: DIt is need to evaluate he changes of the bio-signals through the hot-cold stimulation in the CV4. Methods: The 30 healthy participants were enrolled and randomly allocated, to one of three groups(10 participants for each group): the hot stone therapy(HST) group, or the cold stone therapy(CST) group or no treatment group(NT). All the participants took a rest for 10 minutes for stability before the test. And additional 10 minute rest after measurements of skin test and sEMG. After that two group received hot or cold stone therapy for 30 minutes and one group treated nothing with HRV test. Results: HRV LF value showed a significant increase over time in all three groups, but there was no significant difference between groups but HRV HF value did not show any significant difference with time in all three groups and there was no significant difference between groups. sEMG value showed a significant increase in the left side of the masseter muscle of the HST group and sebum levels was a significant decreased in HST group but no significant meaning was found. Conclusion: There was no objective evidence that hot-cold stimulation produced bio-signals changes in comparison to the control group, but additional studies are needed as the subjects were limited.
Kim, Min-Chan,Yook, Jeong-Hwan,Yang, Han-Kwang,Lee, Hyuk-Joon,Sohn, Tae-Sung,Hyung, Woo-Jin,Ryu, Seung-Wan,Kurokawa, Yukinori,Kim, Young-Woo,Han, Sang-Uk,Kim, Hyung-Ho,Park, Do-Joong,Kim, Wook,Lee, Sa Williams & Wilkins Co 2015 Medicine Vol.94 No.41
<P><B>Abstract</B></P><P>The aim of this study was to evaluate the treatment and prognosis of gastric gastrointestinal stromal tumors (GISTs) according to the 7th UICC/AJCC tumor-node-metastasis (TNM) system and the modified National Institutes of Health (NIH) risk classification. The study cohort consisted of 1057 patients with gastric GIST who underwent surgery between January 2000 and December 2007 from 13 institutions in Korea and 2 in Japan. Clinicopathologic characteristics, surgical outcomes, recurrence, and 5-year recurrence-free survival were evaluated.</P><P>The mean age of the patients was 58.6 years. Thirty patients (2.8%) had distant metastasis preoperatively. Median tumor size was 4.0 cm. Complete resection (R0 resection) was achieved in 1018 patients (96.3%). Eighty-six patients (8.1%) had postoperative complications, and 2 patients (0.2%) died within 30 days after surgery. According to the 7th UICC/AJCC TNM system, 5-year recurrence-free survival rates were 95% to 99% in stage I, 94.1% in stage II, 74.1% in stage IIIA, 48.6% in stage IIIB, and 50.0% in stage IV patients. On survival analysis of high-risk patients according to the TNM system, the 5-year recurrence-free survival rates were 91.6% in stage II, 74.1% in stage IIIA, and 48.6% in stage IIIB patients. Independent factors of recurrence following surgery for gastric GIST were gender, tumor size, mitotic count, and radicality on multivariate analysis.</P><P>The treatment outcome and prognosis of gastric GIST in Korea and Japan seem more favorable compared to those in Western countries. Compared to the modified NIH risk classification, the 7th UICC/AJCC TNM system is more reflective of the 5-year recurrence-free survival of patients with gastric GIST.</P>
Difference between Right and Left Facial Surface Electromyography in Healthy People
Kim, Bo-Hyun,Kim, Kyeong Han,Kim, Lak-Hyung,Kim, Jong-Uk,Yook, Tae-Han Hindawi 2018 Evidence-based Complementary and Alternative Medic Vol.2018 No.-
<P><B>Introduction</B></P><P> The study was to see whether there were differences in values of facial surface electromyography in subjects of good heath by muscles, age, and sex.</P><P><B> Methods</B></P><P> It draws ratio between lower value and higher value (R-LV/HV) and asymmetry index (AI), based on root mean square (RMS) from measurement of facial surface electromyography (sEMG) in 154 people of healthy people (male:female = 70:84) aging between more than 20 and less than 70.</P><P><B> Results</B></P><P> For R-LV/HV, it averages 81.70±14.60% on frontalis muscle, 73.74±19.12% on zygomaticus muscle, and 79.72±14.77% on orbicularis oris muscle. With analysis of the AI average was 10.87±10.14% on frontalis muscle, 16.71±14.79% on zygomaticus muscle, and 12.10±10.05% on orbicularis oris muscle. Both values were statistically significant in three parts of muscles as shown. Both of R-LV/HV and AI show no statistically significant difference on age and sex (p>0.05).</P><P><B> Conclusions</B></P><P> It could provide basic data for the future diagnosis of facial nerve palsy patients by measuring facial sEMG values for healthy people.</P>
Simulation and Experimental Study of A TLP Type Floating Wind Turbine with Spoke Platform
Kim, Hyuncheol,Kim, Imgyu,Kim, Yong Yook,Youn, DongHyup,Han, Soonhung Korean Society of Ocean Engineers 2016 Journal of advanced research in ocean engineering Vol.2 No.4
As the demand for renewable energy has increased following the worldwide agreement to act against global climate change and disaster, large-scale floating offshore wind systems have become a more viable solution. However, the cost of the whole system is still too high for practical realization. To make the cost of a floating wind system be more economical, a new concept of tension leg platform (TLP) type ocean floating wind system has been developed. To verify the performance of a 5-MW TLP type ocean floating wind power system designed by the Korea Advanced Institute of Science and Technology, the FAST simulation developed by the National Renewable Energy Laboratory is used. Further, 1/50 scale model tests have been carried out in the ocean engineering tank of the Research Institute of Medium and Small Shipbuilding, Korea. This paper compares the simulation and ocean engineering tank test results on motion prediction and tension assessment of the TLP anchor.
Targeting mutant <i>KRAS</i> with CRISPR-Cas9 controls tumor growth
Kim, Wonjoo,Lee, Sangeun,Kim, Han Sang,Song, Minjung,Cha, Yong Hoon,Kim, Young-Hoon,Shin, Jeonghong,Lee, Eun-Seo,Joo, Yeonsoo,Song, Jae J.,Choi, Eun Ju,Choi, Jae W.,Lee, Jinu,Kang, Moonkyung,Yook, Jon Cold Spring Harbor Laboratory Press 2018 Genome Research Vol.28 No.3
<P>KRAS is the most frequently mutated oncogene in human tumors, and its activating mutations represent important therapeutic targets. The combination of Cas9 and guide RNA from the CRISPR-Cas system recognizes a specific DNA sequence and makes a double-strand break, which enables editing of the relevant genes. Here, we harnessed CRISPR to specifically target mutant KRAS alleles in cancer cells. We screened guide RNAs using a reporter system and validated them in cancer cells after lentiviral delivery of Cas9 and guide RNA. The survival, proliferation, and tumorigenicity of cancer cells in vitro and the growth of tumors in vivo were determined after delivery of Cas9 and guide RNA. We identified guide RNAs that efficiently target mutant OAS without significant alterations of the wild-type allele. Doxycycline-inducible expression of this guide RNA in KRAS-mutant cancer cells transduced with a lentiviral vector encoding Cas9 disrupted the mutant KRAS gene, leading to inhibition of cancer cell proliferation both in vitro and in vivo. Intra-tumoral injection of lentivirus and adeno-associated virus expressing Cas9 and sgRNA suppressed tumor growth in vivo, albeit incompletely, in immunodeficient mice. Expression of Cas9 and the guide RNA in cells containing wild-type KIZAS did not alter cell survival or proliferation either in vitro and in vivo. Our study provides a proof-of-concept that CRISPR can be utilized to target driver mutations of cancers in vitro and in vivo.</P>