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Prognostics of Power MOSFET Using Artifcial Neural Network Approach
Neeraj Khera,Shakeb A. Khan 대한전기학회 2020 Journal of Electrical Engineering & Technology Vol.15 No.1
This paper presents the prognostics of in-circuit power MOSFETs in power electronic systems using artifcial neural network (ANN). Recent industrial surveys on reliability of power electronic systems shows that the switching transistors are one of most life-limiting component and thermal stress is major cause for their parametric degradation. The on-state drain-source resistance (Rds(on)) is an important fault signature parameter of power MOSFET which increases with its junction temperature rise. In this work, ANN is used to estimate variation in Rds(on) of target MOSFETs at diferent operating conditions. The data set for training and testing of proposed back-propagation trained artifcial neural network are experimentally obtained from the developed test bed. Using test bed, the electrical stressed based accelerated aging test is performed on target power MOSFETs by subjecting them to repetitive unclamped inductive switching at diferent operating frequency and temperature. After of-line training, the proposed ANN is implemented using National Instruments LabVIEW software to estimate realtime Rds(on) values of in-circuit MOSFETs. For this purpose, voltage fed half bridge inverter circuit is designed and target MOSFETs are taken at output section of the circuit. A low cost microcontroller is programmed for acquiring and serially transmitting the real-time data set of target MOSFETs to the LabVIEW software. The performance of the proposed method is evaluated in real time by comparing the ANN estimated Rds(on) value with the experimental obtained value for in-circuit target MOSFETs at test condition.
Delayed Spontaneous Thrombosis of Neglected Direct Carotid-Cavernous Fistula: A Case Report
Tiwari Sarbesh,Garg Pawan Kumar,Khera Pushpinder Singh,K.B Santosh Babu,Yadav Taruna,Sureka Binit 대한신경중재치료의학회 2020 Neurointervention Vol.15 No.2
Direct carotid-cavernous fistula (CCF) refers to direct communication between the cavernous portion of the internal carotid artery (ICA) and the cavernous sinus due to rent in the ICA, most commonly secondary to trauma. These are generally high-flow fistula and rarely resolve spontaneously. We report a case of a young male who developed features of direct CCF after trauma, was denied any treatment for 4 years, and then presented with spontaneous thrombosis of the fistula and a residual large pseudoaneurysm of the cavernous segment of the right ICA, which was subsequently managed with parent vessel occlusion.
Nomura, Akihiro,Won, Hong-Hee,Khera, Amit V.,Takeuchi, Fumihiko,Ito, Kaoru,McCarthy, Shane,Emdin, Connor A.,Klarin, Derek,Natarajan, Pradeep,Zekavat, Seyedeh M.,Gupta, Namrata,Peloso, Gina M.,Borecki, Grune & Stratton 2017 Circulation research Vol.121 No.1
<P>Conclusions: Compared with noncarriers, carriers of PTV at CETP displayed higher high-density lipoprotein cholesterol, lower low-density lipoprotein cholesterol, lower triglycerides, and lower risk for CHD.</P>
Seasonal Changes in Concentrations of Proteins and Lipids in Growing Goat Oocytes
Sangha, G.K.,Bhatia, H.,Khera, K.S. Asian Australasian Association of Animal Productio 2007 Animal Bioscience Vol.20 No.1
Proteins and lipids not only provide a source of energy to the cell, but also play vital roles in modifying the physical properties and function of the biological membranes. In the present study, we investigated the biochemical constituents, viz. proteins and lipids, in growing oocytes of goat antral follicles during summer and winter seasons. Goat genitalia in phosphate buffered saline (pH 7.4) were brought to the laboratory within one hour of slaughter under aseptic conditions at $37^{\circ}C$. Oocytes were aspirated from normal small (<3 mm in diameter) and large (>3 mm) follicles and pooled for biochemical estimations. A significant increase in the amount of protein and lipid was observed with the growth of the oocyte. The amount of protein varied non-significantly with the season, while the amount of lipid varied significantly. The amounts of phospholipid, cholesterol, free fatty acid, and triglyceride increased with the growth of the oocyte, but no significant effect of season in these constituents was observed. Lysolecithin, sphingomyelin, and sterols were the polar lipids identified in both oocytes prepared from small follicles (small oocytes) as well as large follicles (large oocytes). In addition, the small oocytes also contained phosphatidyl serine, while large oocytes contained phosphatidyl glycerol phosphate and phosphatidyl inositol. Among non-polar lipids, triglycerides and long chain alcohols appear only in small oocytes and not in large oocytes. Monoglycerides, 1,2-diglycerides, 1,3-diglycerides and o-dialkyl glycerol ethers, fatty acids, fatty acid methyl esters, and wax esters were identified in both small and large oocytes. Information on biochemical composition of growing oocytes is relevant to oocyte and embryo competence, culture and cryopreservation.
Vascular tumors of the liver: A brief review
Sujata Sarangi,Balamurugan Thirunavukkarasu,Sudeep Khera,Selvakumar B,Taruna Yadav 한국간담췌외과학회 2023 Annals of hepato-biliary-pancreatic surgery Vol.27 No.4
Vascular tumors of the liver are mesenchymal lesions from endothelial cells. They range from common benign lesions such as haemangioma, intermediate tumors like Kaposi sarcoma, and perivascular epithelioid cell tumor to malignant tumors such as hepatic epithelioid hemangioendothelioma and hepatic angiosarcoma in adults. Pediatric vascular tumors of the liver also include benign, locally aggressive, borderline, and malignant masses with haemangiomas being the most common benign tumors and epithelioid hemangioendothelioma being an uncommon pediatric malignancy. The list of these lesions is completed by nodular regenerative hyperplasia, solitary fibrous tumour, and hepatic small vessel neoplasms (HSVN). Some of these tumors are uncommon and rare. This review article aimed to enumerate hepatic vascular tumors along with their imaging, histopathology, molecular findings for accurate diagnosis that can result in better management.
Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels
CHARGE-Heart Failure Consortium,CARDIoGRAM Exome Consortium,Emdin, C.A.,Khera, A.V.,Natarajan, P.,Klarin, D.,Won, H.H.,Peloso, G.M.,Stitziel, N.O.,Nomura, A.,Zekavat, S.M.,Bick, A.G.,Gupta, N.,Asselta Elsevier Inc. 2016 Journal of the American College of Cardiology Vol.68 No.25
<P>CONCLUSIONS Beyond CHD, genetically lowered Lp(a) levels are associated with a lower risk of peripheral vascular disease, stroke, heart failure, and aortic stenosis. As such, pharmacological lowering of plasma Lp(a) may influence a range of atherosclerosis-related diseases. (C) 2016 by the American College of Cardiology Foundation.</P>
Cascade of Complications Following Carotid Body Tumor Excision
Pawan K Garg,Sarbesh Tiwari,Tushar S Ghosh,Surendra Patel,Ankur Sharma,Pushpinder S Khera 대한신경중재치료의학회 2021 Neurointervention Vol.16 No.3
Carotid body tumor excision can lead to various complications including vascular injury and pseudoaneurysm formation. Here we describe a case of carotid body tumor excision followed by series of complications including pseudoaneurysm formation, failure of primary surgical repair, carotid stump syndrome following parent artery occlusion, and persistent hypotension.