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Phenotypic Characterization of Genetically Lowered Human Lipoprotein(a) Levels
CHARGE-Heart Failure Consortium,CARDIoGRAM Exome Consortium,Emdin, C.A.,Khera, A.V.,Natarajan, P.,Klarin, D.,Won, H.H.,Peloso, G.M.,Stitziel, N.O.,Nomura, A.,Zekavat, S.M.,Bick, A.G.,Gupta, N.,Asselta Elsevier Inc. 2016 Journal of the American College of Cardiology Vol.68 No.25
<P>CONCLUSIONS Beyond CHD, genetically lowered Lp(a) levels are associated with a lower risk of peripheral vascular disease, stroke, heart failure, and aortic stenosis. As such, pharmacological lowering of plasma Lp(a) may influence a range of atherosclerosis-related diseases. (C) 2016 by the American College of Cardiology Foundation.</P>