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Single-Port Robotic Cholecystectomy: Early Experience from 8 Cases
( Hyung Jun Kwon ),( Horyon Kong ),( Sang Geol Kim ),( Yun Jin Hwang ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1
Aims: Single-port laparoscopic cholecystectomy (SPLC) is a technical concept to reduced pain and improve cosmetic results when compared to multi-port cholecystectomy. However, SPLC is associated with technical limitation due to the enhanced complexity of the approach and limited number of specialized instruments or platforms. On the other hand, using a robotic platform may overcome these problems and enable more precise surgical actions by increasing freedom of movement and by restoring intuitive instrument control. In this presentation, we report the early clinical experience of our first 8 sing-port robotic cholecystectomy (SPRC) cases. Methods: Between November 2016 and February 2017, eight patients underwent SPRC with the da Vinci Xi robot and single-site instrumentation. We retrospectively reviewed clinical data on those patients. Results: All of 8 patients had completion of SPRC. Seven patients were female and one was male. Average patient age was 43.3±11.8 years and BMI was 22.4±1.4 kg/m2. Three patients (37.5%) were diagnosed with chronic calculous cholecystitis. Three patients (37.5%) underwent operation for polypoid lesions of the gallbladder. One patient (12.5%) was diagnosed with acute calculous cholecystitis. The mean operation time (skin-to-skin) was 83.9±30.7 min, docking time was 13.25±8.1 min, and console time was 42.1±26.4 min. The intraoperative blood loss was negligible. The mean Visual Analog Pain Scale score 6hr after the surgery was 2.9±0.4. The mean length of hospital stay average postoperative hospital stay was 2.3±1.0 day. There were no intraoperative complication and one patient developed seroma on port site. Conclusions: Robotic single-port cholecystectomy appears feasible and safe in our early experience.
Comparison of the Antibacterial Properties of Phage Endolysins SAL-1 and LysK
Jun, Soo Youn,Jung, Gi Mo,Son, Jee-Soo,Yoon, Seong Jun,Choi, Yun-Jaie,Kang, Sang Hyeon American Society for Microbiology 2011 Antimicrobial Agents and Chemotherapy Vol.55 No.4
<B>ABSTRACT</B><P>In spite of the high degree of amino acid sequence similarity between the newly discovered phage endolysin SAL-1 and the phage endolysin LysK, SAL-1 has an approximately 2-fold-lower MIC against several<I>Staphylococcus aureus</I>strains and higher bacterial cell-wall-hydrolyzing activity than LysK. The amino acid residue change contributing the most to this enhanced enzymatic activity is a change from glutamic acid to glutamine at the 114th residue.</P>
Web Log Analysis Using Support Vector Regression
Jun, Sung-Hae,Lim, Min-Taik,Jorn, Hong-Seok,Hwang, Jin-Soo,Park, Seong-Yong,Kim, Jee-Yun,Oh, Kyung-Whan 한국통계학회 2003 Communications for statistical applications and me Vol.10 No.1
Due to the wide expansion of the internet, people can freely get information what they want with lesser efforts. However without adequate forms or rules to follow, it is getting more and more difficult to get necessary information. Because of seemingly chaotic status of the current web environment, it is sometimes called "Dizzy web" The user should wander from page to page to get necessary information. Therefore we need to construct system which properly recommends appropriate information for general user. The representative research field for this system is called Recommendation System(RS), The collaborative recommendation system is one of the RS. It was known to perform better than the other systems. When we perform the web user modeling or other web-mining tasks, the continuous feedback data is very important and frequently used. In this paper, we propose a collaborative recommendation system which can deal with the continuous feedback data and tried to construct the web page prediction system. We use a sojourn time of a user as continuous feedback data and combine the traditional model-based algorithm framework with the Support Vector Regression technique. In our experiments, we show the accuracy of our system and the computing time of page prediction compared with Pearson's correlation algorithm.algorithm.
Yun, Tae Sik,Lin, Chunmei,Yon, Jung-Min,Park, Seul Gi,Gwon, Lee Wha,Lee, Jong-Geol,Baek, In-Jeoung,Nahm, Sang-Seop,Lee, Beom Jun,Yun, Young Won,Nam, Sang-Yoon The Korean Society of Veterinary Science 2018 大韓獸醫學會誌 Vol.58 No.4
Although hyaluronic acid (HA) has been developed as a nanoparticle (NP; 320-400 nm) for a drug delivery system, the tissue targeting efficacy and the pharmacokinetics of HA-NPs are not yet fully understood. After a dose of 5 mg/kg of cyanine 5.5-labeled HA-NPs or HA-polymers was intravenously administrated into mice, the fluorescence was measured from 0.5 h to 28 days. The HA-NPs fluorescence was generally stronger than that of HA-polymers, which was maintained at a high level over 7 days in vivo, after which it gradually decreased. Upon ex vivo imaging, liver, spleen, kidney, lung, testis and sublingual gland fluorescences were much higher than that of other organs. The fluorescence of HA-NPs in the liver, spleen and kidney was highest at 30 min, where it was generally maintained until 4 h, while it drastically decreased at 1 day. However, the fluorescence in the liver and spleen increased sharply at 7 days relative to 3 days, then decreased drastically at 14 days. Conversely, the fluorescence of HA-polymers in the lymph node was higher than that of HA-NPs. The results presented herein may have important clinical implications regarding the safety of as self-assembled HA-NPs, which can be widely used in biomedical applications.
THE INTERACTION OF PIROXICAM WITH SOME METAL IONS IN AQUEOUS SOLUTION
YUN, SOCK SUNG,CHOI, HYOUNG NAE,KANG, JUN GILL,YOON, MINJOONG,CHOI, SUNG NAK 충남대학교 기초과학연구소 1989 연구논문집 Vol.9 No.-
The interaction of various metal ions, such as Co(Ⅱ), Cu(Ⅱ), La(Ⅲ), Ce(Ⅲ), Y(Ⅲ) and Al(Ⅲ), with piroxicam in aqueous solution has been studied by spectroscopic methods. The interaction of the metal lions with HMBDC (4-hydroxy-2-methyl-1,2λ-benzothiazine-1,1-dioxide-3-methyl-carboxylate) has also been studied for comparison. It was found that Al(Ⅲ) and Y(Ⅲ) ions interact significantly with both piroxicam and HMBDC to form 1:1 complexes in aqueous solution. The stability constants of the complexes have been determined at μ → 0. The thermodynamic parameters for the complex formations have also been calculated from the Gibbs-Helmholtz plot. On the basis of the spectroscopic and thermodynamic evidence, the binding sites of piroxicam and HMBDC to the metal ions are suggested.