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Serum Sickness-like Reaction in a Patient with an Acute Exacerbation of Hepatitis B
( Jong Baik Kim ),( Hyun Ok Son ),( Sin Wook Chun ),( Suk Young Lee ),( Byung In Ro ),( Han Kyoung Cho ),( Han Gyu Choi ) 대한피부과학회 2017 大韓皮膚科學會誌 Vol.55 No.2
Serum sickness-like reaction (SSLR) is an abnormal self-limited reaction that can cause fever, myalgia, fatigue, lymphadenopathy, arthralgia, and skin rashes. Its etiology is yet unknown; however, SSLR often develops in patients with hepatitis B and after drug and vaccination administration. SSLR`s typical cutaneous manifestations include polycyclic, erythematous wheal-like or plaque-like lesions. A 47-year-old male hepatitis B carrier visited our emergency department with high fever and multiple annular erythematous plaques with clear centers on his trunk and upper and lower extremities. The patient`s hematologic laboratory results indicated an acute exacerbation of hepatitis B, and his symptoms correlated with those of SSLR. Here, we report a case of SSLR in a patient with an acute exacerbation of hepatitis B with clinical, hematological, and histopathological evidence. (Korean J Dermatol 2017;55(2):132∼ 135)
Clinical Analysis of 1,360 Patients Presenting with Male Pattern Hair Loss
( Jong Baik Kim ),( Byung In Ro ) 대한피부과학회 2017 大韓皮膚科學會誌 Vol.55 No.7
Background: To date, numerous studies have investigated the epidemiology and clinical characteristics of male pattern hair loss (MPHL). Objective: The purpose of this study was to evaluate a large number of long-term MPHL patients and to compare them to shorter term ones from other studies. Methods: We retrospectively reviewed charts of patients diagnosed with MPHL during a 10-year period at the alopecia clinic at the Department of Dermatology of Myongji Hospital. Results: Among 3,549 alopecia patients who had visited the hospital`s alopecia clinic, 1,360 were patients demonstrating MPHL (38.3%). The most frequent age group was patients in their 20`s (30.1%) followed by those in their 30`s (28.2%), 40`s (17.2%), 50`s (9.9%), and teenagers (8.9%). There were 599 MPHL patients (44.0%) with a paternal familial predisposition, 182 (13.4%) with a maternal familial predisposition, and 118 (8.7%) with familial predisposition on maternal and paternal sides. MPHL was classified based on the Norwood-Hamilton classification: type 2 (20.0%), type 3v (19.4%), and type 3a (16.3%) were the most frequent. Abnormalities in total serum cholesterol were found in 15.1% patients and triglycerides in 36.1% of patients. The most common comorbidity was seborrheic dermatitis, followed by hypertension, hyperlipidemia, diabetes mellitus, and gastrointestinal diseases. Conclusion: This study demonstrated that the period of MPHL diagnosis and treatment becomes earlier in age and milder regarding MPHL type, which may be due to early puberty in teenagers. (Korean J Dermatol 2017;55(7):421 ∼426)
Jong-Won Baik,Jin-Tae Hong,Young-Won Yun,Ki-Wan Oh 한국독성학회 2003 Toxicological Research Vol.19 No.4
This study was performed to investigate the effects of glycine on the development of tolerance to and physical dependence on morphine. Repeated administration of morphine (10 mg/kg) developed tolerance and physical dependence. Glycine (100, 200 and 400 mg/kg) was administered intraperitoneally (i.p.) to mice for 7 days prior to the morphine injection. Analgesic effects were estimated by the tail flick methods. The inhibitory degree of the development of morphine-induced analgsic tolerance by i.p. administration of glycine was evidenced by the increase in analgesic response to morphine. Glycine inhibited the development of tolerance to morphine. In addition, we separately measured jumping response as the naloxone-precipitated withdrawal sign in mice that had received the same morphine. Glycine reduced the number of jumping behaviors in morphine dependent mice. These results suggest that glycine might be useful the prevention or treatment of morphine tolerance and physical dependence.
The Study on Impacts of Mega Container ships on Ports
( Jong Sil Baik ) 한국물류학회 2017 The Pan-Pacific Journal of Supply Chain Management Vol.1 No.1
Ships are getting bigger in size and mega ships are the new generation of container ships. Good signal of market, economic and commercial advantages offered by mega ships outweigh its limitations that liner operators make a lot of effort to overcome. As each alliance has placed orders for large vessels, it has placed pressure on others to follow to ensure unit cost parity. Seeing port calls increasingly rationalised by alliance members, ports face the probability of squeezed margins for the business that they retain as alliances look to joint bargaining to secure volume-related discounts. Mega container ships had brought about cost savings for carriers, decreased maritime transport costs and as such facilitated global trade in the past. However, larger ships require somewhat adaptations of port infrastructure, container handling equipment and cause larger peaks in container traffic in ports, with wide ranging impacts. Both developments in the liner shipping market have a major impact on the ports and terminal operations. Therefore, this paper will discuss the overview of container ship development, the reasons for the strong development of the ship size for the last period and important commercial and technical challenge as its limitation. Moreover, the paper will focus on the strategies for liner operators and how to deal with mega ships. And this report assesses if the benefits of the current mega container ships still outweigh their costs to the whole transport chain.
Jong Wook Baik,Sang Hee Lee,Doo Won Lee,Soo Hong Lee 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.68 No.9
Ni/Cu two-step plating is a promising metallization technique because low contact resistance and improved contact adhesion can be achieved after the Ni annealing process. Also, narrow fingers, which are required for high-efficiency solar cells, can be formed by plating. However, the reliability of contact adhesion is still considered one obstacle to industrializing solar cells with plated metal contacts. In this experiment, the influence of ARC opening methods on plated contact adhesion was investigated because the roughnesses of the Si surfaces produced by using pico-second laser ablation and photolithography may be different. Also, the annealing process was conducted before and after plating Cu/Ag metal stacks. The sequence of the annealing can be significant for efficient production because plating is a wet process while annealing is a dry process. The contact adhesion was measured by using a peel-off test. The test was conducted on a 1.5-mm-wide by a 60 70- mm-long bus bar area. A 3.2-N/mm adhesion force was recorded as a highest average value along the bus bar.