일측성 질폐쇄 및 동측 신장 무발생을 동반한 중복자궁 2예

윤일영,여소진,김형문,김정식,김태희,이해혁,남계현,이권해,김준모,김민의 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Uterus didelphys with unilateral obstructed hemivagina and ipsilateral renal agenesis usually presents after menarch with progressive abdominal pain during menses secondary to hematocolpos, and indeed a very rare congenital anomaly due to Mullerian duct malformation. An accurate and prompt diagnosis is of importance to permit treatment and to assure the future fertility of the patient. Pelvic ultrasound, physical examination and pelvic MRI established a diagnosis of hematometracolpos secondary to uterus didelphys with unilateral imperforate hemivagina. An incision in the vaginal septum allowed drainage of the hematocolpos, providing relief of the patients symptoms. We report two case of uterus didelphys with obstructed hemivagina with brief review of the literature.

니파팜, 핑거루트 추출물을 함유한 O/W 화장품 제형 개발 및 분석

전유진(Yue Jin Jun),김진희(Jin-Hee Kim),진병석(Byung Suk Jin) 한국응용과학기술학회 (구.한국유화학회) 2021 한국응용과학기술학회지 Vol.38 No.4

니파팜과 핑거루트 추출물이 화장품 천연원료 소재로 활용 가능성을 살펴보기 위하여 두 추출 물을 함유한 O/W 화장품 제형을 제조하였다. 제조된 화장품 제형들의 외관을 비교하고, 색차계를 사용하여 명도와 색상 값을 측정하였다. 또한 조성을 달리한 제형들의 pH, 점도, 텍스처 등을 측정하면서 추출물 들이 제형의 물성에 미치는 영향을 살펴보았다. 마지막으로 화장품 제형들의 UV 투과율 및 SPF 지수를 비교 관찰하면서 핑거루트 추출물이 자외선 차단의 천연원료 소재로서의 사용 가능성을 확인하였다. This study was attempted to investigate the availability of nipa palm (Nypa fruticans Wurmb.) and finger root (Boesenbergia pandurata) extracts as natural cosmetic ingredients. For this, O/W cosmetic formulations with different compositions were prepared. The appearance of the cosmetic formulations was compared, and brightness and color values were measured using a colorimeter. Also, the pH, viscosity, and texture of the cosmetic formulations with different compositions were measured, and the effects of the extracts on the properties of the cosmetic formulations were examined. Finally, the UV transmittance and sun protection factor (SPF) index were observed, and the results confirmed the availability of finger root extract as a natural ingredient for UV protection.

Macrophages Promote Coal Tar Pitch Extract-induced Tumorigenesis of BEAS-2B Cells and Tumor Metastasis in Nude Mice Mediated by AP-1

Zhang, Peng,Jin, Yue-Fei,Zhang, Qiao,Wu, Yi-Ming,Wu, Wei-Dong,Yao, Wu,Wu, Yong-Jun,Li, Zhi-Tao,Zhao, Yong,Liu, Yu,Feng, Fei-Fei Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12

Background: We sought to evaluate the role of tumor associated macrophages (TAMs) on the promotion of coal tar pitch extract (CTPE)-induced tumorigenesis of human bronchial epithelial cells (BEAS-2B) and tumor metastasis in nude mice, and related mechanisms. Materials and Methods: BEAS-2B cells were first treated with 2.4 mg/mL CTPE for 72 hours. After removal of CTPE, the cells were continuously cultured and passaged using trypsin-EDTA. THP-1 cells were used as macrophage-like cells. BEAS-2B cells under different conditions (n=6/group) were injected into the back necks of nude mice, and alterations of tumor xenograft growth, indicative of tumorigenicity, and tumor metastasis were determined. Pathological changes (tumor nests and microvascular lesions) of HE-stained tumor tissues were also evaluated. The expression of AP-1(c-Jun) in xenografts and metastatic tumors was determined using immunohistochemistry. Results: Tumor size and weight in nude mice transplanted with the mixture of CTPE-induced passage 30 BEAS-2B and THP-1 cells (2:1) were increased compared to those from the CTPE-treated BEAS-2B cells at passage 30 alone at different observation time points. Tumor metastasis to lymph nodes and liver was only detected after transplantation of a mixture the two kinds of cells. The numbers of tumor nests and microvascular lesions, and the expression levels of AP-1 (c-Jun) in tumors from the mixture of two kinds of cells were increased apparently in contrast to those in tumor from the CTPE-treated BEAS-2B cells of passage 30 alone. In addition, there was positive correlation between AP-1 (c-Jun) expression level and the number of microvascular lesions, or between AP-1 (c-Jun) expression level and tumor metastasis in these two groups. Conclusions: TAMs not only facilitate tumorigenesis transformation of CTPE-induced BEAS-2B cells, but also promote tumor growth, angiogenesis and metastasis in nude mice in vivo, which may be mediated by AP-1.

Lack of association between the VEGFA gene polymorphisms and preterm birth in Korean women

Yue Shi,Hyung Jun Kim,Seong Yong Kim,Ga Eun Kim,Han Jun Jin Korea Genome Organization 2023 Genomics & informatics Vol.21 No.3

Preterm birth (PTB), a pregnancy-related disease, is defined as a birth before 37 weeks of gestation. It is a major cause of maternal mortality and morbidity worldwide, and its incidence rate is steadily increasing. Various genetic factors can contribute to the etiology of PTB. Vascular endothelial growth factor A (VEGFA) gene is an important angiogenic gene and its polymorphisms have been reported to be associated with PTB development. Therefore, we conducted a case-control study to evaluate the association between VEGFA rs699947, rs2010963, and rs3025039 polymorphisms and PTB in Korean women. A total of 271 subjects (116 patients with PTB and 155 women at ≥38 weeks of gestation) were analyzed in this study. The genotyping of VEGFA gene polymorphisms was performed using polymerase chain reaction- restriction fragment length polymorphism. No significant association between the patients with PTB and the control groups was confirmed. In the combination analysis, we found a significant association between PTB and VEGFA rs699947 CC-rs2010963 GG-rs3025039 CC combination (odds ratio, 3.77; 95% confidence interval, 1.091 to 13.032; p = 0.031). The VEGFA rs699947, rs2010963, and rs3025039 polymorphisms might have no genetic association with the pathogenesis of PTB in Korean women. However, the combination analysis indicates the possibility that VEGFA acts in PTB pathophysiology. Therefore, larger sample sets and replication studies are required to further elucidate our findings.

Reports ; Adrenergic receptor β2 activation by stress promotes breast cancer progression through macrophages M2 polarization in tumor microenvironment

( Jun-fang Qin ),( Feng-jiao Jin ),( Ning Li ),( Hai-tao Guan ),( Lan Lan ),( Hong Ni ),( Yue Wang ) 생화학분자생물학회 2015 BMB Reports Vol.48 No.5

Stress and its related hormones epinephrine (E) and norepinephrine (NE) play a crucial role in tumor progression. Macrophages in the tumor microenvironment (TME) polarized to M2 is also a vital pathway for tumor deterioration. Here, we explore the underlying role of macrophages in the effect of stress and E promoting breast cancer growth. It was found that the weight and volume of tumor in tumor bearing mice were increased, and dramatically accompanied with the rising E level after chronic stress using social isolation. What is most noteworthy, the number of M2 macrophages inside tumor was up-regulated with it. The effects of E treatment appear to be directly related to the change of M2 phenotype is reproduced in vitro. Moreover, E receptor ADRβ2 involved in E promoting M2 polarization was comprehended simultaneously. Our results imply psychological stress is influential on specific immune system, more essential for the comprehensive treatment against tumors. [BMB Reports 2015; 48(5): 295-300]

Properties of ABS/PMMA Binary Blend and ABS/PMMA/MBS Ternary Blend

Jin Ding,ZhenMing Yue,Jiao Sun,JiCui Zhou,Jun Gao 한국고분자학회 2016 폴리머 Vol.40 No.5

An analysis was performed on the effects of rubber particle size on the mechanical and optical properties of the acrylonitrile-butadiene-styrene (ABS)/poly(methyl methacrylate) (PMMA) blend and the ABS/PMMA/methacrylate-butadiene-styrene (MBS) blend. This work found that when the particle size is 0.22-0.23 μm, the impact strength value of the ABS/PMMA blend is at its maximum and is the same as that of the ABS/PMMA/MBS blend. The optimum particle size is effective in toughening because it can trigger the shear yielding mechanism of the matrix. The miscibility and surface glossiness of the blends with 0.22 μm particle size were also much better than those of the blends with other particle sizes. This work provides new insights into the synergistic roles of rubber particle size and core-shell modifier in the toughening of ABS/PMMA blend with good impact toughness and high surface glossiness.

The Opacity and Physical Property of Paper Influenced by Using Mixed Fillers

Zi-yue Mo,Li-jun Wang,Guang-fan Jin,Jun-Hyunh Cho 한국펄프·종이공학회 2018 한국펄프·종이공학회 학술발표논문집 Vol.2018 No.4

Experimental study on the injection and spray characteristics of biodiesel and diesel fuel within a common rail system

( Hao Yue Zhu ),( Zhen Huang ),( Jin Xiao ),( Jun Xing Hou ) 한국액체미립화학회 2010 한국액체미립화학회 학술강연회 논문집 Vol.2010 No.-

In this paper, the injection characteristics and macroscopic spray behavior of biodiesel and diesel fuel within a common rail system are investigated. The injection rate is measured with Bosch method, spray visualization system is employed to study the macroscopic spray characteristics of both fuels. The results show that the injection delays of biodiesel and diesel are almost the same. Comparing to diesel, injection duration of biodiesel is a little longer and injection fuel quantity is a little larger. The macroscopic spray result shows, with increased injection pressure, the tip penetration of biodiesel becomes longer and the spray cone angle becomes larger. When ambient pressure increases, the injection tip penetration becomes shorter and the spray cone angle becomes larger. Comparing to diesel, injection tip penetration of biodiesel is longer and spray cone angle is smaller, because the kinematic viscosity and surface tension of biodiesel are larger than those of diesel. The difference of spray characteristics of both fuels is no longer obvious under higher injection pressure. With increased ambient pressure, the difference of spray tip penetration of both fuels becomes larger, and the difference of spray cone angle become smaller.

Genome-wide identification and characterization of the Dof gene family in moso bamboo (Phyllostachys heterocycla var. pubescens)

Tao Wang,Jin-Jun Yue,Xue-Ji Wang,Lu Xu,Lu-Bin Li,Xiao-Ping Gu 한국유전학회 2016 Genes & Genomics Vol.38 No.8

The Dof (DNA binding with One Finger) family of single zinc finger proteins is a family of plant-specific transcription factors. These transcription factors have a variety of important functions in different biological processes in plants. In the current study, we identified 26 Dof family genes in moso bamboo (Phyllostachys heterocycla var. pubescens). A complete overview of PhDof genes in moso bamboo is presented, including the gene structures, phylogeny, protein motifs and expression patterns. Phylogenetic analysis of the 26 PhDof proteins identified four classes constituting seven clusters (A, B1, C1, C2, D1, D2 and D3). In addition, a comparative analysis between the Dof genes in moso bamboo, Arabidopsis (Arabidopsis thaliana L.) and rice (Oryza sativa L.) was also performed, and several putative paralogous and orthologous genes were identified. The exon numbers in Dof genes ranged from one to three in many plants; however, the exon number in PhDofs ranged from one to four. The PhDof genes displayed differential expression in different parts of the shoot and at different flower development stages. This study represents the first step towards a genome-wide analysis of the Dof genes in moso bamboo. Our study provides a useful reference for cloning and functional analysis of members of the Dof gene family in moso bamboo and other species.

Homologous sense and antisense expression of a gene in Dunaliella tertiolecta

Zhang, Jing Yue,Jeon, Hancheol,Sim, Sang Jun,Lee, Yew,Jin, EonSeon Springer-Verlag 2015 Planta Vol.242 No.4