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      • SCIESCOPUSKCI등재

        Optimum Design of Transverse Flux Machine for High Contribution of Permanent Magnet to Torque Using Response Surface Methodology

        Xie, Jia,Kang, Do-Hyun,Woo, Byung-Chul,Lee, Ji-Young,Sha, Zheng-Hui,Zhao, Sheng-Dun The Korean Institute of Electrical Engineers 2012 Journal of Electrical Engineering & Technology Vol.7 No.5

        Transverse flux machine (TFM) has been proved to be very suitable for high-torque, low-speed, and direct-drive situation in industry. But the complex structures and costly permanent magnets (PMs) are two key limitations of its wide range of applications. This paper proposes a new claw pole TFM (ACPTFM) which features an assembled claw pole stator and using the lamination steels material to overcome the complex structures. By combining response surface methodology (RSM) with design of experiment, an optimum design method is put forward to improve the PM's contribution to the torque in order to save the PM's amount. The optimum design results demonstrate the validity of the proposed optimum design method and the optimized model. Eventually, the finite-element analysis (FEA) calculation method, which is used in the optimization process, is verified by the experiments in a prototype.

      • KCI등재

        Optimum Design of Transverse Flux Machine for High Contribution of Permanent Magnet to Torque Using Response Surface Methodology

        Jia Xie,Do-Hyun Kang,Byung-Chul Woo,Ji-Young Lee,Zheng-Hui Sha,Sheng-Dun Zhao 대한전기학회 2012 Journal of Electrical Engineering & Technology Vol.7 No.5

        Transverse flux machine (TFM) has been proved to be very suitable for high-torque, lowspeed, and direct-drive situation in industry. But the complex structures and costly permanent magnets (PMs) are two key limitations of its wide range of applications. This paper proposes a new claw pole TFM (ACPTFM) which features an assembled claw pole stator and using the lamination steels material to overcome the complex structures. By combining response surface methodology (RSM) with design of experiment, an optimum design method is put forward to improve the PM’s contribution to the torque in order to save the PM’s amount. The optimum design results demonstrate the validity of the proposed optimum design method and the optimized model. Eventually, the finiteelement analysis (FEA) calculation method, which is used in the optimization process, is verified by the experiments in a prototype.

      • KCI등재

        Effects of astaxanthin on antioxidant capacity of golden pompano (Trachinotus ovatus) in vivo and in vitro

        ( Jia-jun Xie ),( Xu Chen ),( Jin Niu ),( Jun Wang ),( Yun Wang ),( Qiang-qiang Liu ) 한국수산과학회 2017 Fisheries and Aquatic Sciences Vol.20 No.2

        The objective of this research was to study the effect of astaxanthin (AST) on growth performance and antioxidant capacity in golden pompano (Trachinotus ovatus) both in vivo and in vitro. In the in vivo study, two diets were formulated with or without astaxanthin supplementation (D1 and D2; 0 and 200 mg/kg) to feed fish for 6 weeks. In the in vitro study, cells from hepatopancreas of golden pompano were isolated and four treatments with or without astaxanthin and H<sub>2</sub>O<sub>2</sub> supplementation were applied (control group: without both astaxanthin and H<sub>2</sub>O<sub>2</sub> treated; H<sub>2</sub>O<sub>2</sub> group: just with H<sub>2</sub>O<sub>2</sub> treated; H<sub>2</sub>O<sub>2</sub> + AST group: with both astaxanthin and H<sub>2</sub>O<sub>2</sub> treated; AST group: just with AST treated). Results of the in vivo study showed that weight gain (WG) and special growth rate (SGR) significantly increased with astaxanthin supplemented (P < 0.05). Feed conversion ratio (FCR) of fish fed D2 diet was significantly lower than that of fish fed D1 diet (P < 0.05). Hepatic total antioxidant capacity (T-AOC) and the reduced glutathione (GSH) of golden pompano fed D2 diet were significant higher than those of fish fed D1 diet (P < 0.05). Superoxide dismutase (SOD) was significantly declined as astaxanthin was supplemented (P < 0.05). Results of the in vitro study showed that the cell viability of H<sub>2</sub>O<sub>2</sub> group was 52.37% compared to the control group, and it was significantly elevated to 84.18% by astaxanthin supplementation (H<sub>2</sub>O<sub>2</sub> + AST group) (P < 0.05). The total antioxidant capacity (T-AOC) and the reduced glutathione (GSH) of cell were significant decreased by oxidative stress from H<sub>2</sub>O<sub>2</sub> (P < 0.05), but it could be raised by astaxanthin supplementation (H<sub>2</sub>O<sub>2</sub> vs H<sub>2</sub>O<sub>2</sub> + AST), and the malondialdehyde (MDA) was significant higher in H<sub>2</sub>O<sub>2</sub> group (P < 0.05) and astaxanthin supplementation could alleviate the cells from lipid peroxidation injury. In conclusion, dietary astaxanthin supplementation can improve the growth performance of golden pompano. Moreover, astaxanthin can improve the golden pompano hepatic antioxidant capacity both in vivo and in vitro study by eliminating the reactive oxygen species.

      • SCOPUSKCI등재

        Effects of astaxanthin on antioxidant capacity of golden pompano (Trachinotus ovatus) in vivo and in vitro

        Xie, Jia-jun,Chen, Xu,Niu, Jin,Wang, Jun,Wang, Yun,Liu, Qiang-qiang The Korean Society of Fisheries and Aquatic Scienc 2017 Fisheries and Aquatic Sciences Vol.20 No.4

        The objective of this research was to study the effect of astaxanthin (AST) on growth performance and antioxidant capacity in golden pompano (Trachinotus ovatus) both in vivo and in vitro. In the in vivo study, two diets were formulated with or without astaxanthin supplementation (D1 and D2; 0 and 200 mg/kg) to feed fish for 6 weeks. In the in vitro study, cells from hepatopancreas of golden pompano were isolated and four treatments with or without astaxanthin and $H_2O_2$ supplementation were applied (control group: without both astaxanthin and $H_2O_2$ treated; $H_2O_2$ group: just with $H_2O_2$ treated; $H_2O_2$ + AST group: with both astaxanthin and $H_2O_2$treated; AST group: just with AST treated). Results of the in vivo study showed that weight gain (WG) and special growth rate (SGR) significantly increased with astaxanthin supplemented (P < 0.05). Feed conversion ratio (FCR) of fish fed D2 diet was significantly lower than that of fish fed D1 diet (P < 0.05). Hepatic total antioxidant capacity (T-AOC) and the reduced glutathione (GSH) of golden pompano fed D2 diet were significant higher than those of fish fed D1 diet (P < 0.05). Superoxide dismutase (SOD) was significantly declined as astaxanthin was supplemented (P < 0.05). Results of the in vitro study showed that the cell viability of $H_2O_2$ group was 52.37% compared to the control group, and it was significantly elevated to 84.18% by astaxanthin supplementation ($H_2O_2$ + AST group) (P < 0.05). The total antioxidant capacity (T-AOC) and the reduced glutathione (GSH) of cell were significant decreased by oxidative stress from $H_2O_2$ (P < 0.05), but it could be raised by astaxanthin supplementation ($H_2O_2$ vs $H_2O_2$ + AST), and the malondialdehyde (MDA) was significant higher in $H_2O_2$ group (P < 0.05) and astaxanthin supplementation could alleviate the cells from lipid peroxidation injury. In conclusion, dietary astaxanthin supplementation can improve the growth performance of golden pompano. Moreover, astaxanthin can improve the golden pompano hepatic antioxidant capacity both in vivo and in vitro study by eliminating the reactive oxygen species.

      • KCI등재

        Efficient Certificateless Signature Scheme on NTRU Lattice

        ( Jia Xie ),( Yupu Hu ),( Juntao Gao ),( Wen Gao ),( Mingming Jiang ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.10

        Because of the advantages of certificateless and no escrow feature over the regular signature and identity-based signature, certificateless signature has been widely applied in e-business, e-government and software security since it was proposed in 2003. Although a number of certificateless signature schemes have been proposed, there is only one lattice-based certificateless signature scheme which is still secure in the quantum era. But its efficiency is not very satisfactory. In this paper, the first certificateless signature scheme on NTRU lattice is proposed, which is proven to be secure in random oracle model. Moreover, the efficiency of the new scheme is higher than that of the only one lattice-based certificateless signature.

      • Colorectal Cancer Mortality Characteristics and Predictions in China, 1991-2011

        Fang, Jia-Ying,Dong, Hong-Li,Sang, Xue-Jin,Xie, Bin,Wu, Ku-Sheng,Du, Pei-Ling,Xu, Zhen-Xi,Jia, Xiao-Yue,Lin, Kun Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17

        Background: To identify the epidemiological characteristics of colorectal cancer mortality in China during the period of 1991-2011, and forecast the future five-year trend. Materials and Methods: Mortality data for colorectal cancer in China from 1991 to 2011 was used to describe epidemiological characteristics in terms of age group, gender, and rural/urban residence. Trend surface analysis was performed to analyze the geographical distribution of colorectal cancer. Four models including curve estimation, time series modeling, gray modeling and joinpoint regression were applied to forecast the trends for the future five years. Results: Since 1991 the colorectal cancer mortality rate increased yearly, and our results showed that the trend would continue to increase in the ensuing 5 years. The mortality rate in males was higher than that of females and the rate in urban areas was higher than in rural areas. The mortality rate was relatively low for individuals less than 60 years of age, but increased dramatically afterwards. People living in the northeastern China provinces or in eastern China had a higher mortality rate for colorectal cancer than those living in middle or western China provinces. Conclusions: The steadily increasing mortality of colorectal cancer in China will become a substantial public health burden in the foreseeable future. For this increasing trend to be controlled, further efforts should concentrate on educating the general public to increase prevention and early detection by screening. More effective prevention and management strategies are needed in higher mortality areas (Eastern parts of China) and high-risk populations (60+ years old).

      • Emodin Inhibits Breast Cancer Cell Proliferation through the ERα-MAPK/Akt-Cyclin D1/Bcl-2 Signaling Pathway

        Sui, Jia-Qi,Xie, Kun-Peng,Zou, Wei,Xie, Ming-Jie Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

        Background: The aim of the present study was to investigate the involvement of emodin on the growth of human breast cancer MCF-7 and MDA-MB-231 cells and the estrogen (E2) signal pathway in vitro. Materials and Methods: MTT assays were used to detect the effects of emodin on E2 induced proliferation of MCF-7 and MDA-MB-231 cells. Flow cytometry (FCM) was applied to determine the effect of emodin on E2-induced apoptosis of MCF-7 cells. Western blotting allowed detection of the effects of emodin on the expression of estrogen receptor ${\alpha}$, cyclin D1 and B-cell lymphoma-2 (Bcl-2), mitogen-activated protein kinases (MAPK) and phosphatidylinostiol 3-kinases (PI3K). Luciferase assays were emplyed to assess transcriptional activity of $ER{\alpha}$. Results: Emodin could inhibit E2-induced MCF-7 cell proliferation and anti-apoptosis effects, and arrest the cell cycle in G0/G1 phase, further blocking the effect of E2 on expression and transcriptional activity of $ER{\alpha}$. Moreover, Emodin influenced the ER ${\alpha}$ genomic pathway via downregulation of cyclin D1 and Bcl-2 protein expression, and influenced the non-genomic pathway via decreased PI3K/Akt protein expression. Conclusions: These findings indicate that emodin exerts inhibitory effects on MCF-7 cell proliferation via inhibiting both non-genomic and genomic pathways.

      • KCI등재

        Particle Swarm Optimization based on Vector Gaussian Learning

        ( Jia Zhao ),( Li Lv ),( Hui Wang ),( Hui Sun ),( Runxiu Wu ),( Jugen Nie ),( Zhifeng Xie ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.4

        Gaussian learning is a new technology in the computational intelligence area. However, this technology weakens the learning ability of a particle swarm and achieves a lack of diversity. Thus, this paper proposes a vector Gaussian learning strategy and presents an effective approach, named particle swarm optimization based on vector Gaussian learning. The experiments show that the algorithm is more close to the optimal solution and the better search efficiency after we use vector Gaussian learning strategy. The strategy adopts vector Gaussian learning to generate the Gaussian solution of a swarm`s optimal location, increases the learning ability of the swarm`s optimal location, and maintains the diversity of the swarm. The method divides the states into normal and premature states by analyzing the state threshold of the swarm. If the swarm is in the premature category, the algorithm adopts an inertia weight strategy that decreases linearly in addition to vector Gaussian learning; otherwise, it uses a fixed inertia weight strategy. Experiments are conducted on eight well-known benchmark functions to verify the performance of the new approach. The results demonstrate promising performance of the new method in terms of convergence velocity and precision, with an improved ability to escape from a local optimum.

      • SCIESCOPUSKCI등재

        A New C-10 Acetylene and A New Triterpenoid from Conyza canadensis

        Xie, Wei-Dong,Gao, Xue,Jia, Zhong Jian 대한약학회 2007 Archives of Pharmacal Research Vol.30 No.5

        From the whole plants of Conyza canadensis (Compositae), a new C-10 acetylene, namely 8R, 9R-dihydroxymatricarine methyl ester (1), and a new triterpenoid, namely 3${\beta}$ 16${\beta}$, 20${\beta}$-trihydroxytaraxast-3-O-palmitoxyl ester (4), were isolated along with eleven known compounds(2, 3, 5-13). The structures of all 13 compounds were elucidated on the basis of their spectral data. The antibacterial activities of compounds 1-3 were evaluated.

      • Evolution of Discussion and Discovery in Chinese Engineering Classrooms: A Pilot Study

        Jia Zhou,Pei-Luen Patrick Rau,Gavriel Salvendy,Anping Xie 대한사고개발학회 2011 The International Journal of Creativity & Problem Vol.21 No.2

        This paper presents the description of a pilot experiment with three classes con ducted in Industrial Engineering classes at Tsinghua University in China (N=125), with the aim of increasing students’ discussions and discovery in the classroom and ultimately increasing students’ engineering creative process. Each class was divided randomly into experimental and control groups. Results indicated that students’ satisfaction increased with some level of discussions in the classroom. But the one semester’s study for the Chinese students did not seem to be sufficient to increase either their generic or engineering specific creativity.

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