Die literarische Negation der bürgerlichen Gesellschaft

Hyeseon Shin 서울대학교 외국어교육연구소 2017 외국어교육연구 Vol.20 No.-

Heinrich Manns Professor Unrat weist charakteristische Merkmale des ‚Gesellschaftsromans’ auf: Repräsentativ zu erwähnen ist die Darstellung der Schule als ein Modell der Gesellschaft. Heinrich Mann zielte mit seinem schulsatirischen Professor Unrat darauf ab, die kaiserliche Bildungsanstalt zu kritisieren, und weitergehend psychologisierende Kritik an der zeitgenössischen bürgerlichen Kultur und Gesellschaft auszuüben. Zu diesem Zweck gestaltet der Autor die Schule und die darin agierende Figuren als eine Art Modell, das in einer vertretenden Funktion für die Gesellschaft steht. Dieses Gesellschaftsmodell führt eine Reflexion über den Bankrott der humanistischen Bildungsvorstellungen in der Wilhelminischen Zeit und ebenso über die Doppelmoral des Bürgertums in der Übergangssituation zur Moderne herbei. Hinsichtlich dieses Gesellschaftsmodells ist zu betrachten, inwiefern das Verfallen der neuhumanistischen Bildungsidee und das Verkommen bürgerlicher Kultur im Roman unterbreitet werden. Vor diesem Hintergrund kann der Protagonist des Romans Professor Unrat als Repräsentant des Bildungsbürgertums dieser Übergangszeit verstanden werden, in der die neuhumanistische Einheit der Bildungstradition verfällt.

Activated Rap1A Induces Osteoblastic Differentiation and Cell Adhesion

Hyeseon Kim,Taeck J. Jeon 조선대학교 기초과학연구원 2016 조선자연과학논문집 Vol.9 No.3

Comparison of Respiratory Outcomes between Less Invasive Surfactant Administration and the Intubation- Surfactant-Extubation Technique in Premature Infants with Respiratory Distress Syndrome

Hyeseon Kim,Hyun Ho Kim,Misun Yang,Yea Seul Han,성세인,So Yoon Ahn,장윤실,박원순 대한신생아학회 2020 Neonatal medicine Vol.27 No.3

Purpose: To compare respiratory outcomes between less invasive surfactant administration (LISA) and the intubation-surfactant-extubation (INSURE) technique in premature infants with respiratory distress syndrome (RDS). Methods: We performed a retrospective medical chart review for 75 premature infants who were born at a gestational age (GA) of ≤34 weeks (between January 2017 and December 2019) and developed RDS after birth. Data on the demographic and outcome variables, including respiratory outcomes, were collected and compared between the infants who received LISA and those who received INSURE as a rescue therapy for RDS. Results: No signifcant differences in GA, birth weight, and other demographic characteristics were found between the LISA and INSURE groups (GA: 28.7 weeks vs. 28.8 weeks, P=0.449; birth weight: 1,236 g vs. 1,124 g, P=0.714). At the delivery room, although the infants showed no significant difference in positive pressure ventilation rate after birth, the LISA group showed a higher rate of continuous positive airway pressure application than the INSURE group. The infants in the LISA group presented a higher risk of requiring multiple doses of surfactant for RDS than the infants in the INSURE group (57% vs. 17.5%, P=0.001). However, the duration of invasive and/ or noninvasive respiratory support and incidence of bronchopulmonary dysplasia showed no signifciant difference between the two groups. Conclusion: In the present study, no significant differences in the incidence of inhospital respiratory outcomes such as bronchopulmonary dysplasia were found between the LISA and INSURE groups. These results suggest that LISA can be an alternative therapeutic option for treating RDS to avoid intubation and mechanical ventilation in premature infants.

Effects of Temperature and Solvents on Enzymatic Synthesis of Hydroxybutyrate Methyl Ester

Hyeseon LEE,Jemin SON,Eunjeong YANG,Chulhwan PARK 한국생물공학회 2022 한국생물공학회 학술대회 Vol.2022 No.4

New Coating Method for Sustained Drug Release: Surface Modification of ePTFE Grafts by inner coating PLGA

Hyeseon Kim,Seohyeon Park,김대중,박종상 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.5

Expanded polytetrafluoroethylene (ePTFE) grafts have been used as vascular access for many patients suffering from end stage renal disease. However, the vascular graft can cause significant clinical problems such as stenosis or thrombosis. For this reason, many studies have been performed to make drug eluting graft, but initial burst is major problem in almost drug eluting systems. Therefore we used biodegradable polymer to reduce initial burst and make sustained drug delivery. The ePTFE grafts were dipped into a paclitaxel-dissolved solution and then PLGA-dissolved solution was passed through the lumen of ePTFE. We analyzed whether the dose of paclitaxel is enough and the loading amount of PLGA on ePTFE graft increases according to the coating solution’s concentration. Scanning electron microscope (SEM) images of various concentration of PLGA showed that the porous surface of graft was more packed with PLGA by tetrahydrofuran solution dissolved PLGA. In addition, in vitro release profiles of Ptx-PLGA graft demonstrated that early burst was gradually decreased as increasing the concentration of PLGA. These results suggest that PLGA coating of Ptx loaded graft can retard drug release, it is useful tool to control drug release of medical devices.

Determination of Major Carbohydrates of Four Different Brown Macroalgae

Hyeseon LEE,Jeongho LEE,Hyeonmi SHIN,Bo Kyeong KIM,Hah Young YOO,Chulhwan PARK 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.4

Estimated rate of agricultural injury

Hyeseon Chae,Kyungdoo Min,kanwoo Youn,Jinwoo Park,Kyungran Kim,Hyocher Kim,Kyungsuk Lee 대한직업환경의학회 2014 대한직업환경의학회지 Vol.26 No.-

Objectives: This study estimated the rate of agricultural injury using a nationwide survey and identified factors associated with these injuries. Methods: The first Korean Farmers’ Occupational Disease and Injury Survey (KFODIS) was conducted by the Rural Development Administration in 2009. Data from 9,630 adults were collected through a household survey about agricultural injuries suffered in 2008. We estimated the injury rates among those whose injury required an absence of more than 4 days. Logistic regression was performed to identify the relationship between the prevalence of agricultural injuries and the general characteristics of the study population. Results: We estimated that 3.2% (±0.00) of Korean farmers suffered agricultural injuries that required an absence of more than 4 days. The injury rates among orchard farmers (5.4 ± 0.00) were higher those of all non-orchard farmers. The odds ratio (OR) for agricultural injuries was significantly lower in females (OR: 0.45, 95% CI = 0.45?0.45) compared to males. However, the odds of injury among farmers aged 50?59 (OR: 1.53, 95% CI = 1.46?1.60), 60?69 (OR: 1.45, 95% CI = 1.39?1.51), and ≥70 (OR: 1.94, 95% CI = 1.86?2.02) were significantly higher compared to those younger than 50. In addition, the total number of years farmed, average number of months per year of farming, and average hours per day of farming were significantly associated with agricultural injuries. Conclusions: Agricultural injury rates in this study were higher than rates reported by the existing compensation insurance data. Males and older farmers were at a greater risk of agriculture injuries; therefore, the prevention and management of agricultural injuries in this population is required.

Ku complex suppresses recombination in the absence of MRX activity during budding yeast meiosis

( Hyeseon Yun ),( Keunpil Kim ) 생화학분자생물학회 2019 BMB Reports Vol.52 No.10

During meiosis, programmed double-strand breaks (DSBs) are repaired via recombination pathways that are required for faithful chromosomal segregation and genetic diversity. In meiotic progression, the non-homologous end joining (NHEJ) pathway is suppressed and instead meiotic recombination initiated by nucleolytic resection of DSB ends is the major pathway employed. This requires diverse recombinase proteins and regulatory factors involved in the formation of crossovers (COs) and non-crossovers (NCOs). In mitosis, spontaneous DSBs occurring at the G1 phase are predominantly repaired via NHEJ, mediating the joining of DNA ends. The Ku complex binds to these DSB ends, inhibiting additional DSB resection and mediating end joining with Dnl4, Lif1, and Nej1, which join the Ku complex and DSB ends. Here, we report the role of the Ku complex in DSB repair using a physical analysis of recombination in Saccharomyces cerevisiae during meiosis. We found that the Ku complex is not essential for meiotic progression, DSB formation, joint molecule formation, or CO/NCO formation during normal meiosis. Surprisingly, in the absence of the Ku complex and functional Mre11-Rad50-Xrs2 (MRX) complex, a large portion of meiotic DSBs was repaired via the recombination pathway to form COs and NCOs. Our data suggested that Ku complex prevents meiotic recombination in the elimination of MRX activity. [BMB Reports 2019; 52(10): 607-612]

Die literarische Negation der bürgerlichen Gesellschaft

Hyeseon Shin 한국외국어교육학회 2017 Foreign languages education Vol.24 No.2

Heinrich Manns Professor Unrat weist charakteristische Merkmale des ‚Gesellschaftsromans’ auf: Repräsentativ zu erwähnen ist die Darstellung der Schule als ein Modell der Gesellschaft. Heinrich Mann zielte mit seinem schulsatirischen Professor Unrat darauf ab, die kaiserliche Bildungsanstalt zu kritisieren, und weitergehend psychologisierende Kritik an der zeitgenössischen bürgerlichen Kultur und Gesellschaft auszuüben. Zu diesem Zweck gestaltet der Autor die Schule und die darin agierende Figuren als eine Art Modell, das in einer vertretenden Funktion für die Gesellschaft steht. Dieses Gesellschaftsmodell führt eine Reflexion über den Bankrott der humanistischen Bildungsvorstellungen in der Wilhelminischen Zeit und ebenso über die Doppelmoral des Bürgertums in der Ü bergangssituation zur Moderne herbei. Hinsichtlich dieses Gesellschaftsmodells ist zu betrachten, inwiefern das Verfallen der neuhumanistischen Bildungsidee und das Verkommen bürgerlicher Kultur im Roman unterbreitet werden. Vor diesem Hintergrund kann der Protagonist des Romans Professor Unrat als Repräsentant des Bildungsbürgertums dieser Ü bergangszeit verstanden werden, in der die neuhumanistische Einheit der Bildungstradition verfällt.

Investigation of Enzyme Stability of Enzymatic Synthesis of Puerarin Palmitate Using Immobilized Thermomyces lanuginosus Lipase

Hyeseon LEE,Eunjeong YANG,Hyeok Ki KWON,Chulhwan PARK 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.10