Antitumor Constituents from Anthriscus Sylvestris (L.) Hoffm

Chen, Hui,Jiang, He-Zhong,Li, Yong-Chao,Wei, Guo-Qing,Geng, Yun,Ma, Chao-Ying Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

Bioassay-guided chemical investigation of the roots of Anthriscus sylvestris (L.) Hoffm. resulted in the isolation of nine compounds, whose structures were determined by spectroscopic methods. Compound 1 was isolated from this plant for the first time and compounds 3 and 9 were first found from this genus. Different polar fractions of A. sylvestris extract and compounds 1, 6-8 and 9 were evaluated for antitumor activities against HepG2 (human hepatocellular carcinoma), MG-63 (human osteosarcoma cells), B16 (melanoma cells) and HeLa (human cervical carcinoma cells) lines by the MTT method. The petroleum ether fraction of A. sylvestris extract exhibited excellent inhibitory activity with an $IC_{50}$ value of $18.3{\mu}g/ml$. Among the isolates from the petroleum ether fraction, compound 7 showed significant inhibition against the growth of the four tumor cells with $IC_{50}$ values ranging from $12.2-43.3{\mu}g/ml$.

Graphite-based selectorless RRAM: improvable intrinsic nonlinearity for array applications

Chen, Ying-Chen,Hu, Szu-Tung,Lin, Chih-Yang,Fowler, Burt,Huang, Hui-Chun,Lin, Chao-Cheng,Kim, Sungjun,Chang, Yao-Feng,Lee, Jack C. The Royal Society of Chemistry 2018 Nanoscale Vol.10 No.33

<P>Selectorless graphite-based resistive random-access memory (RRAM) has been demonstrated by utilizing the intrinsic nonlinear resistive switching (RS) characteristics, without an additional selector or transistor for low-power RRAM array application. The low effective dielectric constant value (<I>k</I>) layer of graphite or graphite oxide is utilized, which is beneficial in suppressing sneak-path currents in the crossbar RRAM array. The tail-bits with low nonlinearity can be manipulated by the positive voltage pulse, which in turn can alleviate variability and reliability issues. Our results provide additional insights for built-in nonlinearity in 1<I>R</I>-only selectorless RRAMs, which are applicable to the low-power memory array, ultrahigh density storage, and in-memory neuromorphic computational configurations.</P>

Fabrication of tubular porous titanium membrane electrode and application in electrochemical membrane reactor for treatment of wastewater

Hui Tong,Chao Yang,Yanqi Lv,Ling Wang,Koucheng Chen,Xingfu Zhou 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.96 No.-

In this study, tubular titanium membrane (TTM) /SnO2-Sb/SnO2-Sb-CeO2 porous anode was fabricatedand used in continuous tubular membrane reactor for electrochemical treatment of dye wastewater. Xraydiffraction (XRD), scanning electron microscopy (SEM) and high-resolution transmission electronmicroscopy (HRTEM) were used to evaluate the morphology and microstructure of the different tubulartitanium membrane. Linear sweep voltammetry (LSV) and accelerated service life test are employed toillustrate the performance of TTM/SnO2-Sb/SnO2-Sb-CeO2 porous membrane electrode. It is found thatTTM/SnO2-Sb/SnO2-Sb-CeO2 active layer on titanium membrane has compact microstructure, high over-potential for oxygen evolution (2.10 V vs saturated calomel electrode). The effects of pore diameter,applied voltage andflow rate on the electro-catalytic property of the tubular porous electrode wereinvestigated. Study shows titanium membrane reactor with an optimized pore diameter of 10 mm has thelowest energy consumption which is important for the practical application of electrochemicaltechnology. The performance of titanium tubular membrane reactor is investigated by treatingmethylene blue (MB) wastewater under the cell voltage of 3.0–4.5 V and theflow rate of 2.5–3.5 L min 1. This continuous titanium membrane electrochemical reactor using solar cell show excellent performancein treating dye wastewater and the further potential application in electrochemical synthesis.

A Fault Diagnostic Method for Position Sensor of Switched Reluctance Wind Generator

Chao Wang,Xiao Liu,Hui Liu,Zhe Chen 대한전기학회 2016 Journal of Electrical Engineering & Technology Vol.11 No.1

Fast and accurate fault diagnosis of the position sensor is of great significance to ensure the reliability as well as sensor fault tolerant operation of the Switched Reluctance Wind Generator (SRWG). This paper presents a fault diagnostic scheme for a SRWG based on the residual between the estimated rotor position and the actual output of the position sensor. Extreme Learning Machine (ELM), which could build a nonlinear mapping among flux linkage, current and rotor position, is utilized to design an assembled estimator for the rotor position detection. The data for building the ELM based assembled position estimator is derived from the magnetization curves which are obtained from Finite Element Analysis (FEA) of an SRWG with the structure of 8 stator poles and 6 rotor poles. The effectiveness and accuracy of the proposed fault diagnosis method are verified by simulation at various operating conditions. The results provide a feasible theoretical and technical basis for the effective condition monitoring and predictive maintenance of SRWG.

Multiaxial Fatigue Life Prediction Based on High-Cycle Uniaxial Fatigue Test of Steel Pipe Weldments with Welding Defects

Hui Liu,Xiu-wen Lv,Shi-chao Chen,Qiang Zhou,Piao Zhou,Wei-lian Qu 한국강구조학회 2023 International Journal of Steel Structures Vol.23 No.1

Welding defects are unavoidable for welded structures, which can lead to fatigue damage even under the random wind load with small amplitude. It is therefore necessary to explore the effect of welding defect on the fatigue properties of welded steel pipes. Three groups of welded steel pipe specimens were designed according to welding defect conditions, i.e. specimens without welding defect (Group I), specimens with incomplete fusion (Group II), and specimens with welding porosity (Group III). Uniaxial tension–compression and torsion high-cycle fatigue tests were carried out. S–N curves of uniaxial tension–compression and torsion tests were obtained by cyclic loading with equal stress amplitude. The test results show that the high-cycle fatigue strength of weldments is obviously lower than that of base metal with the same strength under uniaxial tension–compression and torsion loading. In addition, the welding defects result in a decrease in fatigue strength, while the decrease extent by welding porosity is greater than that by incomplete fusion. Finally, because of the inherent multiaxial loading characteristics of welded structures, the high-cycle multiaxial fatigue life of steel pipe weldments was also predicted by using the modified Wöhler curve method based on the uniaxial fatigue test results. It can be found that when the stress amplitude is constant, the fatigue life of welded steel pipe decreases and the modified Wöhler curves move downward more quickly with the increase of damage parameter defined as the ratio of normal stress amplitude to shear stress amplitude on the critical plane, which means that normal stress amplitude will accelerate the cracks growth and result in faster failure of the weld materials.

Facile hydrophilic modification of polydimethylsiloxane-based sponges for efficient oil–water separation

Chao-Jen Wang,Wei-Fan Kuan,Hui-Ping Lin,Yury A. Shchipunov,Li-Jen Chen 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.96 No.-

In this study, an eco-friendly fabrication process for the hydrophilic polydimethylsiloxane (PDMS)-basedsponge was proposed with the assistance of sugar templates and poly(dimethylsiloxane-b-ethyleneoxide) (PDMS-b-PEO) block copolymer additives. The effects of sugar loadings and sugar particle sizes onsponge structure and separation performance were investigated. Manipulating sugar loadings exhibiteda unique control over the porosity of sponge, which further influenced the absorption capacity and oil–water separation speed. Additionally, the surface modification of PDMS sponge from hydrophobic/oleophilic to hydrophilic/underwater oleophobic was achieved by incorporating PDMS-b-PEO. Suchmodified sponge demonstrated an underwater oil contact angle of 154 and a stable separation efficiencygreater than 99.9% in the gravity-driven cycledfiltration tests. The hydrophilic PDMS-b-PEO modifiedsponges highlighted herein reveal a promising potential for novel separation materials with energyefficientand cost-effective features, which are ideal for oil spill clean-up events and wastewatertreatment application.

Event-Triggered Media Stream Bandwidth Adjustment in IoT-Based Home Networks

Chao-Yu Hsu,Chin-Lin Hu,Kun-Sheng Huang,Yung-Hui Chen,Jiun-Long Huang 한국통신학회 2020 한국통신학회 APNOMS Vol.2020 No.09

As the coming maturity of Internet of Things, many home-networked devices with various sensors are deployed in residential environments. It is important to accommodate many devices that compete for bandwidth allocation to transmit data inwards and outwards through a certain home network domain. This paper proposes a novel mechanism which can adjust media stream qualities and transmission bandwidth allocations to different devices. This mechanism is agile against dynamic changes of data workload and finite network resources between inside and outside of a home network. Practical demonstration exhibits that the effects are able to maintain differentiated media transfer services in IoT-based home networks.

Rapid determination of residual formaldehyde in formaldehyde related polymer latexes by headspace gas chromatography

Hui-Chao Hu,Xin-Sheng Chai,Ying-Xin Tian,Wei-Feng Si,Gang Chen 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.3

This paper reports on a headspace gas chromatographic method (HS-GC) for the determination of residual formaldehyde in formaldehyde related polymer latexes. The method is based on the reaction between formaldehyde and borohydride in a sodium hydroxide solution (1 mol/L), in which formaldehyde is quantitatively converted to methanol within 30 min at 90 8C and then determined by HS-GC. The results showed that the repeatability of the method had a relative standard deviation of less than 5.0%; the limit of quantification (LOQ) was 17.3 mg, and the recovery ranged from 96.2–102%. The present method is simple, rapid, and accurate.

Mahonia oiwakensis Extract and Its Bioactive Compounds Exert Anti-Inflammatory Activities and VEGF Production Through M2-Macrophagic Polarization and STAT6 Activation

Yea-Chen Liu,Yu-Ying Hsiao,Kuo-Lung Ku,Hui-Fen Liao,Wei-Chun Chao 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.7

Macrophages play an indispensable role in the host immune defense. Macrophages can undergo polarization into classically (M1) and alternatively (M2) activated macrophages. M1 macrophages activate immune and inflammatory response, while M2 macrophages are involved in tissue remodeling. Mahonia oiwakensis (Mo) is a herbal medicine in Asia used for its anti-inflammatory and analgesic properties; however, the mechanism is unclear. This study analyzed the effect of Mo extracts and its effects on the polarization of both macrophage RAW264.7 cells and mouse splenic macrophages. Water (Mo-W) and EtOH extracts (Mo-E) did not change the viability of RAW264.7 cells, whereas Mo-E inhibited nitric oxide (NO) production. The major compounds, berberine and palmatine, decreased the viability and NO levels of cells. The secretion of inflammatory cytokines CXCL16, IL-6, L-selectin, MCP1, RANTES, and sTNF-R1 was downregulated, whereas the production of vascular endothelial growth factor (VEGF) was upregulated by Mo-E, berberine, and palmatine treatments. Mo-E, berberine, and palmatine stimulated the expression of macrophage CD68 and M2-type CD204 markers, decreased M1-mediated p-STAT1 and NF-κB, and increased M2-mediated p-STAT6 expression. Similar effects on M2 polarization were also observed in splenic macrophages from mice. In conclusion, Mo-E, berberine, and palmatine modulated macrophages through the suppression of M1-mediated inflammation and the recruitment of M2-mediated VEGF secretion and STAT6 expression.

A Fault Diagnostic Method for Position Sensor of Switched Reluctance Wind Generator

Wang, Chao,Liu, Xiao,Liu, Hui,Chen, Zhe The Korean Institute of Electrical Engineers 2016 Journal of Electrical Engineering & Technology Vol.11 No.1

Fast and accurate fault diagnosis of the position sensor is of great significance to ensure the reliability as well as sensor fault tolerant operation of the Switched Reluctance Wind Generator (SRWG). This paper presents a fault diagnostic scheme for a SRWG based on the residual between the estimated rotor position and the actual output of the position sensor. Extreme Learning Machine (ELM), which could build a nonlinear mapping among flux linkage, current and rotor position, is utilized to design an assembled estimator for the rotor position detection. The data for building the ELM based assembled position estimator is derived from the magnetization curves which are obtained from Finite Element Analysis (FEA) of an SRWG with the structure of 8 stator poles and 6 rotor poles. The effectiveness and accuracy of the proposed fault diagnosis method are verified by simulation at various operating conditions. The results provide a feasible theoretical and technical basis for the effective condition monitoring and predictive maintenance of SRWG.