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Theoretical analysis of simply supported channel girder bridges
Hong-Song Hu,Jian-Guo Nie,Yu-Hang Wang 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.56 No.2
Channel girder bridges that consist of a deck slab and two side beams are good choices for railway bridges and urban rail transit bridges when the vertical clearance beneath the bridge is restricted. In this study, the behavior of simply supported channel girder bridges was theoretical studied based on the theory of elasticity. The accuracy of the theoretical solutions was verified by the finite element analysis. The global bending of the channel girder and the local bending of the deck slab are two contributors to the deformations and stresses of the channel girder. Because of the shear lag effect, the maximum deflection due to the global bending could be amplified by 1.0 to 1.2 times, and the effective width of the deck slab for determining the global bending stresses can be as small as 0.7 of the actual width depending on the width-tospan ratio of the channel girder. The maximum deflection and transversal stress due to the local bending are obtained at the girder ends. For the channel girders with open section side beams, the side beam twist has a negligible effect on the deflections and stresses of the channel girder. Simplified equations were also developed for calculating the maximum deformations and stresses.
( Ji Hu ),( Zhen Yuan Song ),( Hong Hong Zhang ),( Xin Qin ),( Shufen Hu ),( Xinghong Jiang ),( Guang Yin Xu ) 대한소화기기능성질환·운동학회 2016 Journal of Neurogastroenterology and Motility (JNM Vol.22 No.1
Background/Aims Patients with long-standing diabetes often demonstrate intestinal dysfunction and abdominal pain. However, the pathophysiology of abdominal pain in diabetic patients remains elusive. The purpose of study was to determine roles of voltage-gated sodium channels in dorsal root ganglion (DRG) in colonic hypersensitivity of rats with diabetes. Methods Diabetic models were induced by a single intraperitoneal injection of streptozotocin (STZ; 65 mg/kg) in adult female rats, while the control rats received citrate buffer only. Behavioral responses to colorectal distention were used to determine colonic sensitivity in rats. Colon projection DRG neurons labeled with DiI were acutely dissociated for measuring excitability and sodium channel currents by whole-cell patch clamp recordings. Western blot analysis was employed to measure the expression of NaV1.7 and NaV1.8 of colon DRGs. Results STZ injection produced a significantly lower distention threshold than control rats in responding to colorectal distention. STZ injection also depolarized the resting membrane potentials, hyperpolarized action potential threshold, decreased rheobase and increased frequency of action potentials evoked by 2 and 3 times rheobase and ramp current stimulation. Furthermore, STZ injection enhanced neuronal sodium current densities of DRG neurons innervating the colon. STZ injection also led to a significant upregulation of NaV1.7 and NaV1.8 expression in colon DRGs compared with age and sex-matched control rats. Conclusions Our results suggest that enhanced neuronal excitability following STZ injection, which may be mediated by upregulation of NaV1.7 and NaV1.8 expression in DRGs, may play an important role in colonic hypersensitivity in rats with diabetes. (J Neurogastroenterol Motil 2016;22:129-140)
Characteristics of failure surfaces induced by embankments on soft ground
Hong, Eun-Soo,Song, Ki-Il,Yoon, Yeo-Won,Hu, Jong-Wan Techno-Press 2014 Geomechanics & engineering Vol.6 No.1
This paper investigates the development of failure surfaces induced by an embankment on soft marine clay deposits and the characteristics of such surfaces through numerical simulations and its comparative study with monitoring results. It is well known that the factor of safety of embankment slopes is closely related to the vertical loading, including the height of the embankment. That is, an increase in the embankment height reduces the factor of safety. However, few studies have examined the relationship between the lateral movement of soft soil beneath the embankment and the factor of safety. In addition, no study has investigated the distribution of the pore pressure coefficient B value along the failure surface. This paper conducts a continuum analysis using finite difference methods to characterize the development of failure surfaces during embankment construction on soft marine clay deposits. The results of the continuum analysis for failure surfaces, stress, displacement, and the factor of safety can be used for the management of embankment construction. In failure mechanism, it has been validated that a large shear displacement causes change of stress and pore pressure along the failure surface. In addition, the pore pressure coefficient B value decreases along the failure surface as the embankment height increases. This means that the rate of change in stress is higher than that in pore pressure.
A prototype MR insertable brain PET using tileable GAPD arrays.
Hong, Key Jo,Choi, Yong,Jung, Jin Ho,Kang, Jihoon,Hu, Wei,Lim, Hyun Keong,Huh, Yoonsuk,Kim, Sangsu,Jung, Ji Woong,Kim, Kyu Bom,Song, Myung Sung,Park, Hyun-Wook The American Association of Physicists in Medicine 2013 Medical physics Vol.40 No.4
<P>The aim of this study was to develop a prototype magnetic resonance (MR)-compatible positron emission tomography (PET) that can be inserted into a MR imager and that allows simultaneous PET and MR imaging of the human brain. This paper reports the initial results of the authors' prototype brain PET system operating within a 3-T magnetic resonance imaging (MRI) system using newly developed Geiger-mode avalanche photodiode (GAPD)-based PET detectors, long flexible flat cables, position decoder circuit with high multiplexing ratio, and digital signal processing with field programmable gate array-based analog to digital converter boards.</P>
Song, Qing-Kun,Li, Jing,Huang, Rong,Fan, Jin-Hu,Zheng, Rong-Shou,Zhang, Bao-Ning,Zhang, Bin,Tang, Zhong-Hua,Xie, Xiao-Ming,Yang, Hong-Jian,He, Jian-Jun,Li, Hui,Li, Jia-Yuan,Qiao, You-Lin,Chen, Wan-Qin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22
Background: The study aimed to describe the age distribution of breast cancer diagnosis among Chinese females for comparison with the United States and the European Union, and provide evidence for the screening target population in China. Materials and Methods: Median age was estimated from hospital databases from 7 tertiary hospitals in China. Population-based data in China, United States and European Union was extracted from the National Central Cancer Registry, SEER program and GLOBOCAN 2008, respectively. Age-standardized distribution of breast cancer at diagnosis in the 3 areas was estimated based on the World Standard Population 2000. Results: The median age of breast cancer at diagnosis was around 50 in China, nearly 10 years earlier than United States and European Union. The diagnosis age in China did not vary between subgroups of calendar year, region and pathological characteristics. With adjustment for population structure, median age of breast cancer at diagnosis was 50~54 in China, but 55~59 in United States and European Union. Conclusions: The median diagnosis age of female breast cancer is much earlier in China than in the United States and the European Union pointing to racial differences in genetics and lifestyle. Screening programs should start at an earlier age for Chinese women and age disparities between Chinese and Western women warrant further studies.
Zheng, Shan,Song, Qing-Kun,Zhao, Lin,Huang, Rong,Sun, Li,Li, Jing,Fan, Jin-Hu,Zhang, Bao-Ning,Yang, Hong-Jian,Xu, Feng,Zhang, Bin,Qiao, You-Lin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5
The aim of this study was to detail characteristics of mammary Paget's disease (PD) representing the whole population in China. A total of 4211 female breast cancer inpatients at seven tertiary hospitals from seven representative geographical regions of China were collected randomly during 1999 to 2008. Data for demography, risk factors, diagnostic imaging test, physical examination and pathologic characters were surveyed and biomarker status was tested by immunohistochemistry. The differences of demography and risk factors between PD with breast cancer and other lesions were compared using Chi-square test or t-test, with attention to physical examination and pathological characters. The percentage of PD was 1.6% (68/4211) in all breast cancers. The mean age at diagnosis was 48.1, and 63.2% (43/68) patients were premenopausal. There is no difference in demography and risk factors between PD with breast cancer and other breast cancer (P > 0.05). The main pattern of PD in physical exam and pathologic pattern were patients presenting with a palpable mass in breast (65/68, 95.6%) and PD with underlying invasive cancer (82.4%, 56/68) respectively. The rate of multifocal disease was 7.4% (5/68). PD with invasive breast cancer showed larger tumor size, more multifocal disease, lower ER and PR expression and higher HER2 overexpression than those in other invasive breast cancer (P < 0.05). These results suggested that PD in China is a concomitant disease of breast cancer, and that PD with underlying invasive cancer has more multiple foci and more aggressive behavior compared with other breast invasive cancer. We address the urgent needs for establishing diagnostic and therapeutic guidelines for mammary PD in China.
Bae Byeonghoon,Hu Kang Hyeck,Song Ji Na,Oh Min Jung,Ryu Si Hong,Jung Hyun-Do,Yoon Chang-Bun 한국세라믹학회 2022 한국세라믹학회지 Vol.59 No.2
The wetting properties of Bi 2 O 3 –ZnO–B 2 O 3 glass composite materials with diff erent ZnO and cordierite contents were investigated upon melting them and thermally treating them at 1300 °C and 430 °C, respectively. The density of a 48%Bi 2 O 3 – 24%ZnO–22% B 2 O 3 glass composite was 7.30 g/cm 3 , which is 99.3% of its theoretical density; its glass softening temperature was 413.2 °C. The addition of cordierite improved the adhesion of the glass by acting as a fi ller, thus lowering its coeffi cient of thermal expansion. Specifi cally, by adding 0–15% cordierite, the coeffi cient of thermal expansion of the Bi 2 O 3 –ZnO–B 2 O 3 glass was reduced from 10.6 × 10 –6 to 7.5 × 10 –6 /K. X-ray diff raction and transmission electron microscopy studies confi rmed that the glass was not crystallized, but rather a composite. This study demonstrates that the Bi 2 O 3 –ZnO–B 2 O 3 glass composite developed herein is an environment-friendly lead-free material that can be sintered at 430 °C without losing its tempered glass function; therefore, this material shows promise for applications in architecture, electronic devices, and home appliances.
Zhong-Ze Han,Hong-De Xu,Kwang-Ho Kim,Tae-Hwan Ahn,Jin-Sook Bae,Ji-Young Lee,Ki-Hyun Gil,Joo-Young Lee,Su-Jung Woo,Hyun-Jung Yoo,Hyun-Kul Lee,Kap-Ho Kim,Chan-Koo Park,Hu-Song Zhang,Si-Whan Song 한국실험동물학회 2010 Laboratory Animal Research Vol.26 No.2
The purpose of this paper is to provide reference data related to the body weight, food & water consumptions, urinalysis, hematology and serum biochemistry parameters and absolute & relative organ weights obtained from control Sprague-Dawley rats, used in the 4-week and 13-week repeated-dose toxicity studies conducted in our laboratory between 2005 and 2008. The mean, standard deviation, minimum and maximum range values for hematology and serum biochemistry parameters, data of absolute & relative organ weights, and the difference between sexes and study duration of week 4 versus 13 week are presented. The studies were conducted according to “the standards of Toxicity Study for Medicinal Products” (2005) and The KFDA Notification No. 2000-63 ‘Good Laboratory Practice (GLP)’ (2000) issued by KFDA. These data could be used as reference material of Sprague-Dawley rats by conducting the studies to evaluate the toxicological profile of pre-clinical toxicity studies.
송재관 ( Jae-gwan Song ),김기학 ( Ki-hak Kim ),허홍석 ( Hong Suk Hu ),박종흥 ( Jong Heung Park ) 한국정보처리학회 2008 한국정보처리학회 학술대회논문집 Vol.15 No.2
최근 물류가 취급되는 발착장에서는 업무효율을 높이기 위해 RFID 시스템을 구축하여 물류의 발착업무를 자동으로 수행하는 사례가 늘고 있다. 본 고는 우편집중국 발착장에 900MHz 대역의 RFID 시스템을 구축하기에 앞서, 시스템을 구성하는 주요 장비의 기능 및 성능을 사전에 검증하고 대상장비의 신뢰성을 제고하고 시간과 노력 및 비용을 줄이기 위해 BMT 를 실시한 내용을 기술한 것이다. BMT 의 주요 항목으로는, RFID 고정형 리더의 전파간섭시험, 주파수 호핑시험, 롤파렛 인식시험 등이었으며, 해당 장비의 기능 및 성능을 기술적으로 검증할 수 있었다.