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Immobilization with Ketamine HCI and Tiletamine-Zolazepam in Cynomolgus Monkeys
Myung-cheol Kim,Sung-hyeok Hong,Soo-jin Lee,Young-suk Kim,Jae-il Lee 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2
with Ketamine HCl and Tiletamine-Zolazepam in Cynomolgus MonkeysJae-il Lee, Sung-hyeok Hong, Soo-jin Lee, Young-suk Kim and Myung-cheol Kim*Laboratory of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, KoreaReceived March 4, 2003 / Accepted July 2, 2003J. Vet. Sci. (2003), 4(2), 187-191JOURNAL OFVeterinaryScience*Corresponding author: Myung-cheol Kim Laboratory of Veterinary Surgery, College of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Korea Tel: +82-42-821-6757, Fax: +82-42-822-4216 E-mail: mckim@cnu.ac.kr
( Sung Noh Hong ),( Young Il Min ),( Jeong Whan Kim ),( Sun Young Lee ),( Won Hyeok Choe ),( In Kyung Sung ),( So Young Kwon ),( Hyung Seok Park ),( Choon Jo Jin ),( Chang Hong Lee ) 대한소화기학회 2007 SIDDS Vol.9 No.-
Background/Aims: Emerging evidence revealed that the metabolic syndrome (MeS) is associated with the risk of colorectal adenoma. In addition, the individual component of MeS may attribute the development of colorectal adenoma respectively. However, there was no previous study to evaluate whether the clustering of multiple components of MeS has a greater impact on risk of colorectal adenoma. Thus, we evaluate that relationship the colorectal adenoma and ``metabolic score``, the sum of the five metabolic syndrome components in age, sex, lifestyle and dietary factor adjusted model. Methods: Cross-sectional data from 126 cases (adenoma group) and 762 adenoma-free controls (control group) who underwent colonoscopies and completed lifestyle and dietary questionnaires at the Health. Promotion Center, Konkuk University Hospital, from July 2006 to June 2007, were used in this analysis. According to the modified ATP III criteria, metabolic syndrome was diagnosed. Multivariable logistic regression was used to estimate the association between ``metabolic score`` and prevalence of colorectal adenoma. Results: The prevalence for metabolic syndrome was 38% in the adenoma group and 24% in the control group. On the multiple logistic regression analyses, metabolic syndrome was found to be associated with increased risk of colorectal adenoma (odds ratio, 1.93; 95% confidence interval, 1.30-2.82). Also, age, sex, lifestyle and dietary factor adjusted odds ratios of colorectal adenoma for accumulation of component of metabolic syndrome of 0, 1, 2, 3, and 4-5 were 1.0 (referent), 2.25, 3.18, 3.64 and 9.28, respectively (95% confidence interval; 2.04, 42.20; p-trend<0.001). Conclusions: The risk of colorectal adenoma was increased as the components of the MeS were accumulated. The clustering of multiple components of MeS appears to have an additive effect on risk of colorectal adenoma.
Production of Bio-Based Isoprene by the Mevalonate Pathway Cassette in Ralstonia eutropha
( Hyeok-won Lee ),( Jung-ho Park ),( Hee-seok Lee ),( Wonho Choi ),( Sung-hwa Seo ),( Irika Devi Anggraini ),( Eui-sung Choi ),( Hong-weon Lee ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.10
Isoprene has the potential to replace some petroleum-based chemicals and can be produced through biological systems using renewable carbon sources. Ralstonia eutropha can produce value-added compounds, including intracellular polyhydroxyalkanoate (PHA) through fatty acid and lipid metabolism. In the present study, we engineered strains of R. eutropha H16 and examined the strains for isoprene production. We optimized codons of all the genes involved in isoprene synthesis by the mevalonate pathway and manipulated the promoter regions using pLac and pJ5 elements. Our results showed that isoprene productivity was higher using the J5 promoter (1.9 ± 0.24 μg/l) than when using the lac promoter (1.5 ± 0.2 μg/l). Additionally, the use of three J5 promoters was more efficient (3.8 ± 0.18 μg/l) for isoprene production than a one-promoter system, and could be scaled up to a 5-L batch-cultivation from a T-flask culture. Although the isoprene yield obtained in our study was insufficient to meet industrial demands, our study, for the first time, shows that R. eutropha can be modified for efficient isoprene production and lays the foundation for further optimization of the fermentation process.
Enhanced efficiency of near-UV LEDs by surface plasmon and magnetic field effects from metal films
Sang-Hyun Hong,Jae-Joon Kim,Byeong-Hyeok Kim,Na-Yeong Kim,Jang-Won Kang 한양대학교 세라믹연구소 2022 Journal of Ceramic Processing Research Vol.23 No.2
The enhanced efficiency of the near-UV (NUV) LEDs was demonstrated by the combinatory effects of surface plasmons (SP)from the Ag p-electrode and out-of-plane magnetic fields from additional Co/Pt multi-layers. By utilizing an InGaN/GaNbasedNUV-LED epilayer including either 100 or 40 nm p-GaN layers, four different flip-chip LEDs were fabricated byselectively adding Co/Pt ferromagnetic multi-layers on the Ag p-electrode. NUV-LEDs with Co/Pt ferromagnetic multi-layerson 100-nm-thick p-GaN showed a 10.1% enhancement of integrated electroluminescence (EL) intensity at a forward currentof 20 mA, mainly due to the out-of-plane magnetic field effect. In LEDs with a 40 nm p-GaN layer, which is consistent withthe penetration depth of SP fields, a further increase of 13.8% can be achieved in the integrated EL intensity at 20 mA,resulted from the additional coupling effect with SP fields. These results indicate that the combination of Ag and Co/Pt multilayers,as the p-electrode of flip-chip LEDs, can increase the efficiency in NUV flip-chip LEDs due to efficient couplings of SPfields and an out-of-plane magnetic field with carriers injected into quantum wells.
( Sung Hyeok Ryou ),( Jong Wook Bae ),( Hyun Jin Baek ),( Doo Hyuk Lee ),( Sang Won Lee ),( Gyu Ho Choi ),( Kyu Hyung Han ),( Se Weon Kim ),( Hyunbeom Kim ),( Goohyeon Hong ) 대한결핵 및 호흡기학회 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4
Pulmonary pneumatoceles are air-filled thin-walled spaces within the lung and are rare in adult cases of pneumonia. We report the case of a 74-year-old male who was admitted with a cough and sputum production. He had been treated with oral dexamethasone since a brain tumorectomy 6 months prior. Contrast-enhanced computed tomography (CT) of the chest revealed a large pneumatocele in the right middle lobe and peripheral pneumonic consolidation. Bronchoalveolar lavage was performed; cultures identified extended-spectrum β-lactamase (ESBL) producing Proteus mirabilis. A 4-week course of intravenous ertapenem was administered, and the pneumatocele with pneumonia resolved on follow-up chest CT. To the best of our knowledge, this is the first reported case of pulmonary pneumatocele caused by ESBL-producing P. mirabilis associated with pneumonia.
Poster Session 1 : Role of carboxy-terminus of p23 in the regulation of its physiological functions
( Sang Hyeok Woo ),( Sung Kwan An ),( Hyeon Ok Jin ),( Hyung Chahn Lee ),( Sung Keum Seo ),( Doo Hyun Yoo ),( Chang Hun Rhee ),( Seok Il Hong ),( In Chul Park ) 한국생화학분자생물학회 (구 한국생화학회) 2005 생화학분자생물학회 춘계학술발표논문집 Vol.2005 No.-