체육수업에 대한 교과 흥미도가 학생들의 학업열의에 미치는 영향

이상섭(Lee, Sang-Sub),조홍식(Cho, Hong-Sik) 한국체육과학회 2015 한국체육과학회지 Vol.24 No.1

The purpose of this study was to investigate the effects of subject interest in physical education classes on academic engagement among students. For that purpose, the investigator found the population in middle and high school students in Gyeonggi Province and sampled 420 students through convenience sampling. Collected data were put to multiple regression analysis with the PASW Version 18 .0 statistical program. The findings were as follows: First, all the sub-factors of subject interest in physical education classes had statistically significant effects on academic engagement(efficacy). Second, all the sub-factors of subject interest in physical education classes had statistically significant effects on academic engagement(commitment) . Third, all the sub-factors of subject interest in physical education classes had statistically significant effects on academic engagement (vitality). Finally, all the sub-factors of subject interest in physical education classes had statistically significant effects on academic engagement (absorption)

체육수업의 재미요인이 학생들의 심리적 유인성향에 미치는 영향

이종철(Lee Jong-Chul),조홍식(Cho Hong-Sik),박윤혁(Park Yoon-Hyuk),이상섭(Lee Sang-Sub) 한국체육과학회 2006 한국체육과학회지 Vol.15 No.3

The purpose of this study was to explore ways to at identifying what factors made students felt enjoyment during physical education class and how much those factors influence on psychological of inducement inclination. To this end, Cluster Random Sampling was used to set up the population with boys and girls middle school students in Kyunggi-do and Inchon-si area. The survey tool was questionnaire and Collected data hereof were analyzed by one way ANOVA analysis and Multiple Regression Analysis with SPSS WIN Ver 11.5. The aforementioned method and procedure led this research to the conclusion as follows. Firstly, out of sub-factors of physical education class enyoyment by middle schoolers' individual characteristics(gender, result), boy students showed more than girl students, in which there were statistically significant difference. Meanwhile, statistically significant difference was not found in free time, explanation and modeling. Secondly, out of sub-factors of psychological of inducement inclination by middle schoolers' individual characteristics(gender, result), boy students' response was higher in senses of confidence, enthusiasm, accomplishment and indulgence than girl students' in which all considers appeared. Thirdly, the effect enjoymant factors of physical education class had statistically significant on sub-factors of psychological of inducement inclination senses of confidence, enthusiasm, accomplishment and indulgence, free time that is a sub-factor of enjoymant which did not had statistically significant influenced on sense of accomplishment.

A Synthetic Naringenin Derivative, 5-Hydroxy-7,4′-diacetyloxyflavanone-<i>N</i>-phenyl Hydrazone (N101-43), Induces Apoptosis through Up-regulation of Fas/FasL Expression and Inhibition of PI3K/Akt Signaling Pathways in Non-Small-Cell Lung Cancer Cells

Bak, Yesol,Kim, Heejong,Kang, Jeong-Woo,Lee, Dong Hun,Kim, Man Sub,Park, Yun Sun,Kim, Jung-Hee,Jung, Kang-Yeoun,Lim, Yoongho,Hong, Jintae,Yoon, Do-Young American Chemical Society 2011 Journal of agricultural and food chemistry Vol.59 No.18

<P>Naringenin, a well-known naturally occurring flavonone, demonstrates cytotoxicity in a variety of human cancer cell lines; its inhibitory effects on tumor growth have spurred interest in its therapeutic application. In this study, naringenin was derivatized to produce more effective small-molecule inhibitors of cancer cell proliferation, and the anticancer effects of its derivative, 5-hydroxy-7,4′-diacetyloxyflavanone-<I>N</I>-phenyl hydrazone (N101-43), in non-small-cell lung cancer (NSCLC) cell lines NCI-H460, A549, and NCI-H1299 were investigated. Naringenin itself possesses no cytotoxicity against lung cancer cells. In contrast, N101-43 inhibits proliferation of both NCI-H460 and A549 cell lines; this capacity is lost in p53-lacking NCI-H1299 cells. N101-43 induces apoptosis via sub-G<SUB>1</SUB> cell-cycle arrest in NCI-H460 and via G<SUB>0</SUB>/G<SUB>1</SUB> arrest in A549 cells. Expression of apoptosis and cell-cycle regulatory factors is altered: Cyclins A and D1 and phospho-pRb are down-regulated, but expression of CDK inhibitors such as p21, p27, and p53 is enhanced by N101-43 treatment; N101-43 also increases expression levels of the extrinsic death receptor Fas and its binding partner FasL. Furthermore, N101-43 treatment diminishes levels of cell survival factors such as PI3K and p-Akt dose-dependently, and N101-43 additionally induces cleavage of the pro-apoptotic factors caspase-3, caspase-8, and poly ADP-ribose polymerase (PARP). Cumulatively, these investigations show that the naringenin derivative N101-43 induces apoptosis via up-regulation of Fas/FasL expression, activation of caspase cascades, and inhibition of PI3K/Akt survival signaling pathways in NCI-H460 and A549 cells. In conclusion, these data indicate that N101-43 may have potential as an anticancer agent in NSCLC.</P>

2,4-bis (p-hydroxyphenyl)-2-butenal (HPB242) induces apoptosis via modulating E7 expression and inhibition of PI3K/Akt pathway in SiHa human cervical cancer cells.

Kim, Man Sub,Kim, Jung Hee,Bak, Yesol,Park, Yun Sun,Lee, Dong Hun,Kang, Jeong Woo,Shim, Jung-Hyun,Jeong, Heon Sang,Hong, Jin Tae,Yoon, Do Young Lawrence Erlbaum Associates, Publishers [etc.] 2012 Nutrition and cancer Vol.64 No.8

<P>The Maillard reaction is a chemical reaction occurring between an amino acid and a reducing sugar, usually requiring thermal processing. Maillard reaction products (MRPs) have antioxidant, antimutagenic, and antibacterial effects, and although 2,4-bis (p-hydroxyphenyl)-2-butenal (HPB242), a fructose-tyrosine MRP, appears to inhibit proliferation of cancer cells, its mechanism of action has not been studied in detail. We found that HPB242 treatment modulated expression of cyclins and tumor suppressor genes in SiHa human cervical cancer cell lines: cyclins and phospho-pRB were downregulated, whereas the expression of CDK inhibitors and p53 was enhanced. HPB242 induced apoptosis dose-dependently by suppressing E7 expression and leading to sub-G1 cell-cycle arrest in SiHa cell lines; treatment also led to the proteolytic cleavage of caspase-3, -9, and poly (ADP-ribose) polymerase. Moreover, HPB242 upregulated Fas expression, altered expressions of pro- and antiapoptotic factors, and also inhibited nuclear translocation of nuclear factor κB and phosphorylation of IκB. HPB242 treatment decreased phosphatidyl inositol-3 kinase and p-Akt expression levels, demonstrating that this survival pathway may also be inhibited by HPB242. Cumulatively, HPB242 promotes apoptosis by influencing E7 expression, inducing cell-cycle arrest at sub-G1 phase, and promoting both intrinsic (mitochondrial) and extrinsic (Fas-dependent) apoptosis in SiHa human cervical cancer cells.</P>

실드공법에 의한 도심지 터널의 해석

이홍주,김수석,진치섭 釜山大學校 都市問題硏究所 1997 都市硏究報 Vol.5 No.-

The use of underground space has been increased according as area of city has been limited by the urban concentration of population. So it was demanded to increasing tunnel, but this tunnel construction was made trouble in open cut method which has been used generally. Consequently, shield tunneling method is highlighting in urban civil. In the past decade soft clay shield tunneling technology have been improved to permit continuous support to the face of a tunnel. These advanced shield can be operated such that in initial heaving is created, this helps to decrease the inward soil movement into the tail void. In this paper, the measurement of slurry shield and EPB shield were used and two dimensional elasto-plastic programs EPSHILD developed for shield tunnel analysis were approved. The excavation steps corresponding with construction stages were settled and heaving load, load factors were considered. This study is based on the instantaneous settlement which is occured in the process of shield construction but not the secondary settlement by consolidation.

Green 정리를 이용한 철근 콘크리트 단주해석

이홍주,박현재,진치섭 釜山大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.53 No.-

구조물 설계에서, 축하중과 2축 휨을 동시에 받는 기둥 설계를 자주 접하게 된다. 이러한 부재의 해석과 설계는, 모멘트 평형에 따른 여러 변수들의 값을 동시에 구하기 위하여 반복적인 작업이 필요하기 때문에 많은 시간을 요구한다. 본 연구에서는 축력과 2축 휨을 받는 철근 콘크리트 단주의 극한강도를 계산할 수 있는 컴퓨터 프로그램 COLI을 개발하였고, Green정리를 사용하여 임의 형상의 역학적 특성을 계산할 수 있는 수치 방법을 제시하였다. In structural design, columns subjected to combined axial load and biaxial bending are frequently encountered. The analysis and design of such members, are both time consuming and demanding because an iterative procedure is required in order to simultaneously evaluate a number of variables to achieve moment equilibrium. A computer program COLI is developed to compute the ultimate strength of reinforced concrete short columns subjected to combined compression and biaxial bending in this paper. A numerical procedure using Green's theorem is presented that calculates the mechanical properties of generic shapes.

A. 高校 科學 (生物·地球科學) 및 數學科 探究學習의 評價模型 定立과 評價紙 開發

李相協,權炳奎,林在圭,孫文求,吳岱燮,楊洪準,梁承榮,姜用熙,林成圭,金正遠,金吉民,兪正在 경북대학교 과학교육연구소 1982 科學敎育硏究誌 Vol.6 No.-

Currently the evaluation of high school science and mathematics learning has been too much knowledge-centered without concerning the inquiring ability or scientific attitude. This study, therefore, was made for the purpose of establishing of evaluation model for high school science (biology and earth science) and mathematics learning and its evaluation items. In this paper, the research was done about three fields, biology, earth science and mathematics. 1. For the biology, the evaluation methods of inquiry learning were studied with the foreign references, and proper evaluation items were suggested. 2. For the earth science, after analizing 5 kinds of earth science textbook of current using in high school, essential 19 items were selected. 5 of them were tested in test group and control group, then, the results were analized. 3. For the mathematice, the teaching elements of「Set」and「Flow chart」in mathematics (Ⅰ) were selected and structured. Detailed teaching objects were established and evaluation items were introduced.

세로토닌성 항우울제가 백서의 Schedule-Induced Polydipsia에 미치는 영향

이기철,이정호,박중섭,최영민,전성일,정홍경,하준명,정재현 대한생물치료정신의학회 1999 생물치료정신의학 Vol.5 No.2

Object : Schedule-induced polydipsia is considered as an animal model of obsessive-compulsive disorder inrats. The authors evaluated the chronic effects of fluoxetine and clomipramine as serotonergic antidepressants and haloperidol as dopaminergic antagonist on the schedule-induced polydipsia in rat.Methods : Spraque-Dawley rats weighing 200-250gm were individually housed, maintained and allowed free access to water for 1 week. And then the rats were placed on a restricted diet. To induce polydipsia, rats were placed in automatic cage where a pellet dispenser automatically dispensed 90mg pellets on a fixed-time 60 seconds(FT 60s) feeding schedule over 150-minute test session for a day. Water was available at all times during the feeding schedule in automatic cage. After 4 weeks of daily exposure to the FT 60s feeding schedule, experimental rats met a predetermined criterion for polydipsic behavior(greater than 3 times of water per session on average). 4 groups of rats were administered fluoxetine(5mg/kg/i.p.), clomipramine(5mg/kg/i.p.), haloperidol(0.1mg/kg/i.p.), vehicle(1cc/kg/i.p.) for 3 weeks. Rats were tested once a week to access schedule induced polydipsic behavior. The chronic effects of experimental drugs on schedule induced polydipsic behavior were analyzed with repeated analysis of variance and Scheffe test as a post-hoc comparison.In order to measure water consumption in non-polydipsic food-deprived rats, a separate group of rats(N=8) were individually housed and given a single bolus(14.5 gm) of food per day which maintained them at their average body weight.Results and Conclusion : The results were as follows ;1) After 4 weeks of daily feeding procedure with fixed time schedule for 60 seconds per day, the experimental group showed significant differences than the control in the amount of water consumption as compared with their baseline water intakes. At the same periods, there were no differences between the experimental group and the control in body weight. 2) The clomipramine treated group and the fluoxetine treated group showed significant decrease in the amount of water intake as compared with their baseline of polydipsic water intakes for 3 weeks of treatment. However, the haloperidol treated group and the vehicle control group showed no changes of amounts of water intake for 3 weeks of treatment as compared with their baseline of polydipsic water intakes. 3) At 2 weeks of drug treatment, clmipramine treated group(16.88±6.51ml) and the fluoxetine treated group(22.50±10.35ml) showed significantly lower amounts of water intake than the haloperidol treated group (41.25±7.06ml) or vehicle control group(37.50±12.54ml). And also the clomipramine treated group(13.75±5.18ml) and the fluoxetine treated group(18.75±3.54ml) showed significantly lower amounts of water intake than the haloperidol group(35.00±11.65ml) and the vehicle control(34.38±6.78ml) at 3 weeks of drug treatment. Above findings suggest that the fixed time feeding procedure for schedule-induced polydipsia as an animal model of obsessive compulsive disorder was effective to the evaluation of pharmacological challenge study. The author confirmed that schedule-induced polydipsia was successfully decreased for 3 weeks of administration of clomipramine and fluoxetine but there was no response to haloperidol.

컴퓨터 프리젠테이션 기법의 활용이 국어과 수업에 미치는 영향

이채연,정홍섭,김주연 신라대학교 교육과학연구소 1999 교육과학연구 Vol.- No.4

주물공장에서 배출되는 플라이애시를 이용한 속빈 시멘트 블록의 강도특성에 관한 실험적 연구

이홍주,권혁우,진치섭 釜山大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.53 No.-

본 연구는 주물공장 플라이애시를 시멘트 대체재로 이용하여 시멘트 블록의 강도특성에 관한 연구를 실험적으로 규명하였다. 본 연구를 위해 Y사에서 주물제조 후 배출되는 플라이애시를 채택하였다. 플라이애시의 특성을 조사한 결과 물리적·화학적 특성은 한국표준규격에서 정한 값을 만족하였으며, 물리적·화학적으로 우수한 것으로 판단되었다. 플라이애시의 성분분석 결과, 분말도와 단위중량이 일반 화력발전소 플라이애시에 비해 크게 측정되었다. 이러한 성질의 차이가 포졸란 활성도와 워커빌리티에서 일반 플라이애시와 서로 다른 메카니즘을 갖게 된다. 시멘트 블록은 플라이애시를 포틀랜드 시멘트 용적의 0%∼50% 만큼씩 대체한 각각의 경우에 대해 제작하여 치수, 흡수율, 및 압축강도를 측정하였으며 측정결과 플라이애시를 시멘트 용적의 5%∼45%까지 대체하였을 때 KS규격에서 정한 속빈 시멘트 블록의 기준치를 만족하는 것을 알 수 있었다. In this paper, as part of a study about the strength properties of cement blocks, using fly as a cement substitution, an experimental study was done. For this purpose, fly ash was sampled from Y casting foundry. First, by looking over the quality of that thing, the following were found; chemical and physical compositions were fit to the value specified in the Korean Standard. On the other hands, that thing was good in chemical and physical phase. After analyzing the results of fly ash, the value of fineness and specific gravity in the casting foundry fly ash was larger than the fly ash at thermoelectric power plant station. Because of this difference, it is expected that pozzolanic activity of concrete using fly ash from the casting foundry will be different from other fly ash. Cement blocks were tested to evaluate block performance when 0 to 50 percent of the portland cement, by volume, was replaced with the fly ashes. As a result, we found that the absorption and strength characteristics of blocks using casting foundry fly ash were over KS criterion when the fly ash replaced 5∼45% of volume of cement.