The Antimutagenic and Antioxidant Effects of Red Pepper Seed and Red Pepper Pericarp (Capsicum annuum L.)

Sim, Ki-Hyeon,Han, Young-Sil The Korean Society of Food Science and Nutrition 2007 Preventive Nutrition and Food Science Vol.12 No.4

In this study, we examined the antimutagenicity of red pepper seed and red pepper pericarp ethanol extracts using the standard Ames test in the presence and absence of S9 mix. The extracts showed inhibitory effects on both the TA98 and TA100 Salmenella Typhimurium strains against the mutagenic activity of promutagen 2-aminoanthracene, and were also protective against the directly acting mutagens sodium azide and 2-nitrofluorene. The red pepper seed elicited stronger antimutagenicity than the red pepper pericarp. Both the red pepper seed and red pepper pericarp directly quenched nitric oxide to different degrees and the scavenging activities increased with increasing concentrations. Nitric oxide scavenging activity ranged from $22{\sim}77%$ in the red pepper seed, and from $36{\sim}49%$ in the red pepper pericarp. The TEAC values for red pepper seed extract were $47.89{\pm}1.64mg\;g^{-1}$ in the ABTS radical scavenging assays, while those of red pepper pericarp extract were $94.18{\pm}1.61mg\;g^{-1}$. Therefore, we conclude that red pepper seed and red pepper pericarp have antimutagenic activities as well as antioxidant activity.

영골(靈骨).강압혈(降壓穴) 자극(刺鍼)이 혈압(血壓)에 미치는 영향(影向)

임영남,심성용,한지완,고호연,박종형,한양희,전찬용,김동우,Yim, Young-Nam,Sim, Sung-Yong,Han, Ji-Wan,Ko, Ho-Yeon,Park, Chong-Hyeong,Han, Yang-Hee,Chun, Chan-Yong,Kim, Dong-Woo 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.2

Objective : The purpose of this study is to evaluate the clinical effect of the non-pharmacological anti-hypertension method, acupuncture, for hypertensive patients. Methods : 26 patients diagnosed with hypertension were each treated by one of three methods: an anti-hypertension drug(adalat soft capsule), venepuncture, and acupuncture. In cases of rising blood pressure, patients were treated by their one of the three methods, and blood pressure was measured at regular intervals. Result : As for the group of acupuncture treated patients on Young-gol(ling-gu) and Gang-ap-hyul(jiang-ya-xue), readings dropped 18.0mmHg in systolic blood pressure and 6.50mmHg in diastolic blood pressure. This was a greater effect than that seen in the venepuncture treated patients. Blood pressure checked one hour after acupuncture treatment showed a greater difference than blood pressure checked after thirty minutes. Conclusion : Safe reductions in blood pressure were observed through the non-pharmacological method of acupuncture on Young-gol(ling-gu) and Gang-ap-hyul(Jiang-ya-xue).

부재료 첨가에 따른 오이지의 펙틴질 변화에 관한 연구

한정희,심영현 서울여자대학교 자연과학연구소 1997 자연과학연구논문집 Vol.9 No.-

부재료 첨가에 따른 오이지의 제조에서 pH, Texture(Blossom end, Middle, Stem end), 펙틴 조성의 변화(AIS, HWSP, HXSP, HCISP), hardness와 펙틴질 사이의 상관관계에 대해서 다음과 같은 결론을 얻었다. 1. 담금액의 pH 대조군과 부재료 첨가군의 pH 변화를 보면 모든 실험군에서 빠른 감소를 보이는데 E처리구는 다른 부재료 첨가군보다 빠른 숙성 7일째에 pH 3.5에 도달하고, 그 수준을 35일까지 유지하여 오이지의 적정 pH인 3.7을 오래 유지하므로써 적당한 산미를 계속 유지하였고, 대조군과 다른 부채료 첨가군에서는 숙성 14일째에 pH 3.5~pH 3.9에 도달하나 숙성 21일째에 다시 빠른 증가를 나타냈다. 2. 조직감 특성 Blossom end 부위에서는 백두웅이 증가하면 산초 5g 경우 시료 C, D에서 최고 hardness를 나타내는 저장기간이 길어지고, 산초 10g첨가군인 E, F, G에서는 백두웅 양 중가시 최고의 hardness를 나타내는 기간이 짧아졌다. Middle에서도 산초 5g첨가군에서는 B, C, 및 F처리군은 숙성 14일째, 시료 A, G에서는 7일째 높은 hardness를 나타냈고, 산초 10g을 첨가한 경우는 D, F처리군에서 최고의 hardness를 나타내어 산초 10g을 첨가할 경우 백두웅 양 증가시 최고 hardness에 이르는 기간이 짧아지는 경향을 나타냈다. Stem end 부위는 시료 A, B, C, F, G에서는 숙성 7일째, 시료 D처리군에서는 14일째, 시료 E처리군에서는 숙성 28일째 가장 높은 hardness를 나타냈다. 결과적으로 산초양이 적은경우(5g) 백두웅 양이 많아야(30g) 저장기간이 연장되며, 오히려 산초양이 많은 경우(10g)는 백두웅 양이 중가할 필요가 없고 어느재료를 얼마나 첨가할 것인지는 개인의 기호에 맞춰야 될것이며, 이는 앞으로 관능평가등의 방법을 통해 연구해 보는 것이 좋을 것이라 생각된다. 현재 결과로는 부재료 첨가시 (시료 C, D) 대조군보다 저장기간 중 완만한 hardness 변화를 나타내므로 저장성 연장에 효과가 있다고 본다. 3. 펙틱조성의 변화 3.1 AIS 함량의 변화 AIS는 숙성기간이 경과하면서 함량이 약간씩 감소함을 나타냈다. 산초 5g첨가군인 경우 백두웅 30g 첨가시 AIS 함량이 완만하게 감소했고, 산초 10g첨가군인 경우 백두웅 20g 첨가시 AIS 함량이 완만하게 감소했다. 3.2 HWSP함량의 변화 HWSP함량은 가용성 팩틴질의 함량을 보는 것으로 숙성됨에 따라 오이지가 연화되면서 그 함량이 증가한다. 산초 5g을 첨가한 경우는 백두웅 양이 증가함에 따라 HWSP 함량이 증가했고, 산초 10g첨가 군에서는 백두웅의 양이 증가하면 HWSP 함량이 E처리군이 F, G처리군보다 낮은 HWSP 함량을 나타냈다. 3.3 HXSP함량의 변화 대조군과 비교시 산초 5g첨가군에서는 백두웅 20g 첨가(시료 C)시 숙성 21일째까지도 높은 HXSP 함량을 보이며, 산초 10g첨가군에서는 백두웅 30g첨가군(시료 G)인 경우에는 28일째까지 높은 HXSP 함량을 나타냈다. 3.4 HCISP함량의 변화 HCISP는 대조군을 비롯하여 모든 부재료 첨가군에서 숙성기간에 따라 감소하였고, 산초 5g첨가군인 경우 백두웅 20g첨가군(시료 C)과 산초 10g첨가군인 경우 백두웅 10g첨가군이(시료 E) 완만히 감소하여 천천히 숙성되는 것으로 저장기간이 연장된다고 생각된다. 4. Hardness와 펙틴질 사이의 상관관계 팩틴물질의 함량과 조직감 측정과의 상관관계로 HCISP의 함량이 증가하면 hardness도 같이 증가하는가를 알아 보았다. 결과적으로 부재료 첨가군에서 대조군 보다 높은 유의성(p<0.001)의 양의 상관관계를 보여 hardness가 단단하면 HCISP 의 함량도 증가한다는 것을 나타냈다. This study was intended to observe the changes of pH, hardness, and pectic substances(AIS, HWSP, HXSP, HCISP) of Korean pickled cucumbers added Sancho and Backdooung to during fermentation for 6 weeks at 25℃. Changes of pH was decreased and later increased. Korean pickled cucumbers added Sancho 10g and Backdooung 10g maintained a sour taste for a long time. Control and minor ingredient treatments were reached pH 3.5~3.9 at 14th day of fermentation, but 21st day of fermentation fast increased. In blossom end, amount of Backdooung was increased ans Sancho 5g(C, D) showed hardness of maximum and period of storing became longer. Sancho 10g(E, F, G) showed hardness of maximum and period of storing shortens. In Middle, Sancho 5g(B, C) showed hardness of maximum at 14th day of fermentation, and Sancho 10g(D, E) showed hardness of maximum at 27th day of fermentation. A and D showed hardness of maximum at 7th day of fermentation. Minor ingredient treatments was longer than control in period of string. when Korean pickled cucumbers added Backdooung 10g to was reciprocal action to Sancho that was high significantly(p<0.001). Content of alcohol insoluble pectin(AIS), sodium hexametaphosphate soluble pectin(HXSP), and HCl soluble pectin(HCISP)were decreased, whereas content of hot water soluble pectin(HWSP) was increased during fermentation. In case of content of AIS, when Sancho 5g added, Backdooung 30G(C) was decreased gradully, and when Sancho 10g added, Backdooung 20g(F) was decreased gradually. Content of HWSP was increased when Sancho 5g added, as amount of Backdooung was increased. Control and Minor ingredient treatments were decreased during fermentation. this was the same as correlation between hardness and pectin substances.

초등학교 과학과 수업에서 STS 수업 모형 적용에 따른 학습자 특성에 대한 연구

한영욱,심재윤 부산교육대학교 교육대학원 2003 논문집 Vol.5 No.-

This study is about the difference of science knowledge achievement of learner's cognition level and their cognition style after developing and applying a science class program of the 575 models which is presented by Iowa Chautauqua Program. In this study, we picked out two classes. a total of 81 elementary students. The STS class model program was applied to the experimental group and the traditional class was applied to the comparison group. Then we looked into the alteration of the science knowledge achievement, the inquiry ability and the attitude toward science. We also studied on the effect of the student's cognition level and their cognitive style which were differently shown in the STS model class. The results of the study are as follows. First, statistics figures of our study after classes show that the experimental group with the STS class model is significantly higher than the comparison group with the attitude toward science. Secondly, in the cognitive levels, the students with STS model class show much higher statistics in inquiry ability of formal operation stage's alteration, in the attitude toward science of transitional stage's alteration. The students of the concrete operation stage show much higher statistics in the science knowledge achievement and in the inquiry ability. Third, in the cognitive style, the statistics shows that students of the field independent group is higher in the alteration of the science knowledge achievement is higher in the change of attitude toward science, compared with the comparison group with the basic traditional class. So far we have found that class with STS model is much more effective in elementary school students' science achievement than the students with the traditional class, not only in the concrete operation stage about the cognitive levels but also in the middle group between the field independent and the field dependent group on the style of cognition Therefore because most students in elementary school belong to concrete operation stage and the lower levels of cognitive level, we can conclude that the class applied with STS model, which is basically focused on the practical life and subject from real life, affects elementary students more effectively.

열악한 조명 환경의 명암도 영상에서 에지정보와 반복과정을 이용한 영상분리

심영석,박성한 漢陽大學校 工學技術硏究所 1997 工學技術論文集 Vol.6 No.1

In this paper, an image-segmentation algorithm using a new gray level thresholding method is proposed in badly illuminated images. Badly illuminated images in general do not have an optimal unique thresholding value. For these images, it is desirable to determine multiple-thresholding values in semented sub-regions. However, in sub-regions which are included inside objects or background, thresholding values can not be directly determined because of an absence of thresholding information. The proposed algorithm first obtains thresholding values in sub-regions where edge information can be provided. Then thresholding values in sub-regions where edge information is absent are determined by using an iterative processing. In this way, a thresholding map, which has information of thresholding values in each sub-region for an original image, is obtained. In the proposed iterative process, statistical information such as the mean and standard deviation of gray level in sub-regions are used. Finally the segmented objects are obtained from an original image using the thresholding map. Experimental results indicate the effectiveness of the proposed algorithm.

초등학교 암석원의 실태분석 및 암석단원 지도를 위한 효과적인 방안 모색

한영욱,심재윤 부산교육대학교 교육대학원 2005 논문집 Vol.7 No.-

본 연구는 암석원의 형태 및 관리 실태, 설치된 암석의 종류 및 암석원에 대한 인식도와 활용도를 알아보기 위해 부산광역시 및 인근 도시의 97개 초등학교를 대상으로 하였으며 설문지에 적극적으로 응답한 22개 초등학교의 암석원에 관한 설문지를 분석하였다. 그 중에서 옥외 암석원을 가진 20개 학교 중 19개 학교에 대해서는 각각의 학교를 직접 방문하여 직접 암석원의 관리상태, 학생들의 관찰 용이도 및 암석의 육안 감정으로 암석명의 정확도를 조사하였다. 연구 결과 과학과 학습지도를 위한 암석원을 갖추고 있는 학교는 전체 표집 학교 수의 약 58%에 지나지 않았으며 암석의 수도 30점 미만이 대부분이었으며 암석원의 형태 및 배열 순서도 한줄로 길게와 무작위로 배열되어 있는 경우가 과반에 이르렀다. 암석원의 활용도 면에서는 77%가 연 1-2회에 한정되어 있으며 수업의 형태도 한 두 가지 방법에 머무르고 있었다. 암석원에 대한 교사들의 인식 부분에 있어서 암석명에 대한 신뢰도는 73%가 신뢰하지 못하고 있으며 암석 학습에 관해 77%의 교사가 도움의 필요성을 인식하고 있었다. 직접 현장을 방문해 조사한 결과 90% 이상의 학교에서 암석명의 정정 필요성이 있었다. This study is focused to propose policy suggestions and recommendations for the improvement of teaching a rocks unit through the analysis of the rocks garden's current status. A survey questionnaire was developed to survey perceptions of teachers and the actual rocks garden's condition and how to using it at 97 elementary schools. Twenty-two out of 97 teachers responded to the questionnaires. On the basic of questionnaire analysis. The findings of this study are as follows. First, there are only 58% elementary schools have the rocks garden for a rocks unit's lesson. Also, usually they have under thirty rocks in there. Second, the majority of the rocks garden were formed only one line and arranged at random. Third, the rocks garden is used once or twice in a year and teachers use a few teaching methods. Forth, on teachers perceptions, 73 percents of theacers don't put confidence in rocks' name and they need to help using the rocks garden and teaching a rocks unit. Fifth, over 90 percents of the rocks garden have wrong name tags. Therefore, they need to make a correction. It is suggested that: First, for the improvement science education, each elementary school essentially have a rocks garden, give an explanation and administer it. Second, whenever the rocks garde is opened for using it, but students have no interest in it. Therefore teachers consider practical using. Third, for the improvement teaching a rock unit, we need to development teaching-learning methods using the rocks garden and expand the reeducation of elementary teachers.

한국인 제2형 당뇨병 환자를 위한 칼로리별 표준식단 적용효과

심기현,한영실 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.1

To develop the diet for Korean type 2 diabetic patients, a consumer survey was conducted (N=35) and was analyzed statistically. The survey compared the results of a questionnaire, somatomety, and blood parameters before and 8 weeks after the experiment. It was divided into Diabetic diet enforcement group (DDE) vs. Non diabetic diet enforcement group (NDDE). There was no significant difference in body weight, body mass index (BMI), body fat, triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) of the subjects before and 8 weeks after the experiment. DDE's average fasting glucose (FBG) and post prandial 2 hours blood glucose (PP2) were significantly decreased before and after the experiment (p<0.05). NDDE's average FBG and PP2 showed no significant difference. In terms of Hemoglobin A C (HbAIC) content, DDE's had significantly decreased level both before and after the experiment (p<0.05), while there was no significant difference in the NDDE group. Cholesterol and High density lipoprotein cholesterol (HDL-C) were significantly different in DDE (p<0.05) both before and after the experiment. Whereas its the case of NDDE, there was no significant difference on the cholesterol and HDL-C, while DDE's showed a significant difference before and after the experiment. In terms of patients distribution depending on their treatment (p<0.05). NDDE had no significant difference before and after the experiment. For an item asking blood glucose control. DDE had significant difference before and after the experiment (p<0.01), while NDDE had no significant difference. For program satisfaction (p<0.05) and health (p<0.001), both the groups changed significantly after the experiment. But there was no significant difference in applying it to their real life after the experiment. Based on these results, DDE had the decreased blood glucose levels. HbA₁C, and cholesterol and increased HDL-C, with decreased rate of the patients taking oral hypoglycemic agents. In addition, many of the patients who participated in the experiment were found to be satisfied with the program, in terms of having less (rouble in glucose control and exhibited improvement in health. Hence, based on the above results it was concluded that program was a very successful one for the treatment of diabetes.

순천향대학교 사회과학대 학생의 진로인식 및 진로지도개선에 관한 연구

심영수,차석빈,김용하,최한준 순천향대학교사회과학연구소 2003 순천향 사회과학연구 Vol.9 No.1

This study conducted an empirical research to find ways to guide the career of college students in the social science at Soonchunhyang university. Research findings are as follows. 1) About 42% respondents answered that they did job-seeking efforts. 2) With regard to job preparing efforts, students spent their time on improving their English ability, major classes, computer ability, and license obtaining. 3) Job-related information sources in the school were not fully utilized by the students. 4) In the future, students hope that our school strengthen its PR efforts, open more English-related classes, improve its school image as a local university, and provide more job-related information The study concludes with implications of the study results and suggestions for career guidance of students.

웹사이트 활용 교육을 통한 초등학교 6학년 환경교육의 적용방안과 효과

한영욱,심재윤 부산교육대학교 교육대학원 2001 논문집 Vol.3 No.-

In this work, web-site data for the environmental education were searched to use the data-bank. Using this data bank, the environmental education of the elementary students was carried out and investigated the effects on the their environmental academic achievements, their studying attitudes and their mechanism of thinking. The results are as follows: (1) Using the various searching program and instruments, the web-site data about the environmental problems were searched and cataloged by classifying the subjects and URL in order to use the environmental education of elementary students. (2) The selected web-site data were turned out to be complete, satisfactory and valuable to study the various subjects and aspects in the textbook and also for the elementary students. (3) The experimental class using these web-site data and the comparable class not using these data were nearly the same in the academic achievement. Some part of the experimental class had more increase in knowledge and the comparable class had better in attitude.

박달나무의 반형매 가계간 Cd Phytoremediation과 축적 특성

오창영,이재천,한심희,김판기 한국농림기상학회 2004 한국농림기상학회지 Vol.6 No.3

The main purpose of this study was to select a B. schmidtii population which has high cadmium tolerance and remediation and to determine the difference of cadmium uptake patterns among populations. One-year-old B. schmidtii seedlings were treated with 0, 0.4, 0.8mM CdSO₄ *3/8H₂O for two months. Cadmium concentrations in different positions of stem and cadmium concentrations and contents of leaves, stems and roots were analyzed. Also soil cadmium concentrations were analyzed. B. schmidtii was highest in root and lowest in shoot tip, showing a gradual decrease from root to shoot tip. The shoot to root Cd concentration ratios were over 1.26. It is concluded that B. schmidtii has good potential for phytoextraction as a shoot accumulator, which can be used for remediation of cadmium-contaminated areas. But tolerance differs between populations. Therefore B. schmidtii should be used as a means of phytoremediation after selection for Cd tolerance is performed.