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Haemin Jeon,Wancheol Myeong,Jae-Uk Shin,Jong-Woong Park,Hyung-Jo Jung,Hyun Myung IEEE 2014 IEEE/ASME transactions on mechatronics Vol.19 No.5
<P>Structural displacement is considered an important indicator to assess structural conditions. To directly measure the displacement in the time domain, a visually servoed paired structured light system was proposed. The system is composed of two sides facing each other, each with one or two lasers that are controlled by a visually servoed two-DOF manipulator, a camera, and a screen. The relative six-DOF displacement between the two sides can be estimated by calculating the positions of the projected laser beams on the screens and the rotation angles of manipulators. To verify the performance of the proposed system, two kinds of field tests were carried out. A prototype of the system was built and installed on a steel frame building structure and a railway bridge, respectively. The estimated displacements were compared with the reconstructed displacement from an accelerometer. The test results verify the performance of the system and its applicability to real structures.</P>
Haemin Lee,Im-Kyung Kim,Man Ki Ju 대한외과학회 2017 Annals of Surgical Treatment and Research(ASRT) Vol.93 No.5
Purpose: Predicting the need for surgical intervention among patients with intestinal obstruction is challenging. The delta neutrophil index (DNI) has been suggested as a useful marker of immature granulocytes, which indicate an infection or sepsis. In this study, we evaluated the impact of the DNI as an early predictor of operation among patients with intestinal obstruction. Methods: A total of 171 patients who were diagnosed with postoperative intestinal obstruction were enrolled in this study. Medical records, including data for the initial CRP level, WBC count, and DNI were reviewed. Receiver operating characteristic (ROC) curves were generated to clarify the optimal DNI cutoff values for predicting an operation. Results: Among the 171 patients, 38 (22.2%) needed surgical intervention. The areas under the initial CRP, WBC, and DNI ROC curves were 0.460, 0.449, and 0.543, respectively. The optimal cutoff value for predicting further surgical intervention according to the initial DNI level was 4.3%. The accuracy of the cutoff value was 74.9%, the sensitivity was 23.7%, and the specificity was 89.5% (positive predictive value, 23.7%; negative predictive value, 89.5%). In the multivariate analysis, initial DNI levels ≥ 4.3% were significantly associated with surgical intervention (odd ratio, 3.092; 95% confidence interval, 1.072–8.918; P = 0.037). Conclusion: The initial DNI level in patients with intestinal obstruction may be a useful predictor for determining the need for surgical intervention.
( Haemin Kim ),( Kuijae Lee ),( Jongchan Chae ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.11
Bacillus subtilis HM1 was isolated from the rhizosphere region of halophytes for its antifungal activity against Colletotrichum acutatum, the causative agent of anthracnose. Treatment of postharvest apples with the cell culture or with a cell-free culture supernatant reduced disease severity 80.7% and 69.4%, respectively. Both treatments also exhibited antifungal activity against various phytopathogenic fungi in vitro. The antifungal substances were purified and analyzed by acid precipitation, gel filtration, high-performance liquid chromatography, and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). Three compounds were identified as fengycin, iturin, and surfactin. The MALDI-TOF/ TOF mass spectrum revealed the presence of cyclized fengycin homologs A and B, which were distinguishable on the basis of the presence of either alanine or valine, respectively, at position 6 of the peptide sequence. In addition, the cyclized structure of fengycin was shown to play a critical role in antifungal activity.
( Haemin Kim ),( Hyo-shin Kim ),( Hyun-hwa Cha ),( Yoo-min Kim ),( Ji-hee Sung ),( Won Joon Seong ),( Soo-young Oh ) 대한산부인과학회 2022 대한산부인과학회 학술대회 Vol.108 No.-
Objective: Early onset fetal growth restriction (FGR) and/or preeclampsia (PE) are the major causes to perinatal morbidity and mortality. Although, the pathophysiology of these obstetric complications has not been revealed yet, we hypothesized that there could be several undiscovered autoantibodies associated with these diseases. In this study, we aimed to develop autoantibodies in maternal serum complicated with early onset FGR and/or PE. Methods: Serum samples from two respective cases of disease (before 32 weeks of gestation) and control (between 24 and 26 weeks of gestation) were analyzed using a slide based high-density protein microarray which can detect 1,800 of proteins. We obtained an A-score based on the signal intensity of 1,800 protein spots and selected the upper 1 percentile protein showing significant bindings. Results: We observed significant bindings in 32 proteins and strong bindings in four proteins (GSTT1, ZBTB16, ILF2 and MX1) in disease group. In control group, there were significant bindings in 27 proteins and strong bindings in seven proteins (EEF1G, GSTT1, HOOK1, MEIS2, MLH1, MX1 and PRKCZ). Interestingly, there was strong bindings in GSTT-1 (Glutathione S-transferase theta-1), which involved in glutathione metabolic process in cytoplasm, both disease and control group implying the importance of glutathione metabolism during pregnancy. Conclusion: We could observe several antibodies showing significant bindings in maternal serum. Further test is performing.