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Inequalities for Chord power integrals
Ge Xiong,Xiaogang Song 대한수학회 2008 대한수학회지 Vol.45 No.2
For convex bodies, chord power integrals were introduced and studied in several papers (see [3], [6], [14], [15], etc.). The aim of this article is to study them further, that is, we establish the Brunn- Minkowski-type inequalities and get the upper bound for chord power integrals of convex bodies. Finally, we get the famous Zhang projection inequality as a corollary. Here, it is deserved to mention that we make use of a completely distinct method, that is using the theory of inclusion measure, to establish the inequality. For convex bodies, chord power integrals were introduced and studied in several papers (see [3], [6], [14], [15], etc.). The aim of this article is to study them further, that is, we establish the Brunn- Minkowski-type inequalities and get the upper bound for chord power integrals of convex bodies. Finally, we get the famous Zhang projection inequality as a corollary. Here, it is deserved to mention that we make use of a completely distinct method, that is using the theory of inclusion measure, to establish the inequality.
INEQUALITIES FOR CHORD POWER INTEGRALS
Xiong, Ge,Song, Xiaogang Korean Mathematical Society 2008 대한수학회지 Vol.45 No.2
For convex bodies, chord power integrals were introduced and studied in several papers (see [3], [6], [14], [15], etc.). The aim of this article is to study them further, that is, we establish the Brunn-Minkowski-type inequalities and get the upper bound for chord power integrals of convex bodies. Finally, we get the famous Zhang projection inequality as a corollary. Here, it is deserved to mention that we make use of a completely distinct method, that is using the theory of inclusion measure, to establish the inequality.
Mechanisms Underlying the Role of Myeloid-Derived Suppressor Cells in Clinical Diseases: Good or Bad
Ge Yongtong,Cheng Dalei,Jia Qingzhi,Xiong Huabao,Zhang Junfeng 대한면역학회 2021 Immune Network Vol.21 No.3
Myeloid-derived suppressor cells (MDSCs) have strong immunosuppressive activity and are morphologically similar to conventional monocytes and granulocytes. The development and classification of these cells have, however, been controversial. The activation network of MDSCs is relatively complex, and their mechanism of action is poorly understood, creating an avenue for further research. In recent years, MDSCs have been found to play an important role in immune regulation and in effectively inhibiting the activity of effector lymphocytes. Under certain conditions, particularly in the case of tissue damage or inflammation, MDSCs play a leading role in the immune response of the central nervous system. In cancer, however, this can lead to tumor immune evasion and the development of related diseases. Under cancerous conditions, tumors often alter bone marrow formation, thus affecting progenitor cell differentiation, and ultimately, MDSC accumulation. MDSCs are important contributors to tumor progression and play a key role in promoting tumor growth and metastasis, and even reduce the efficacy of immunotherapy. Currently, a number of studies have demonstrated that MDSCs play a key regulatory role in many clinical diseases. In light of these studies, this review discusses the origin of MDSCs, the mechanisms underlying their activation, their role in a variety of clinical diseases, and their function in immune response regulation.
Ge Tian,Li Xiong,Wenhua Lin,Jinghao Han,Xiang-Yan Chen,Thomas Wai Hong Leung,Yannie Oi Yan Soo,Lawrence Ka Sing Wong 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.3
Background and PurposezzExternal counterpulsation (ECP) is a noninvasive method used to enhance cerebral perfusion by elevating the blood pressure in ischemic stroke. However, the response of the beat-to-beat blood pressure variability (BPV) in ischemic stroke patients during ECP remains unknown. MethodszzWe enrolled recent ischemic stroke patients and healthy controls. Changes in the blood fow velocities in bilateral middle cerebral arteries and the continuous beat-to-beat blood pressure before, during, and afer ECP were monitored. Power spectral analysis revealed that the BPV included oscillations at very low frequency (VLF; <0.04 Hz), low frequency (LF; 0.04– 0.15 Hz), and high frequency (HF; 0.15–0.40 Hz), and the total power spectral density (TP; <0.40 Hz) and LF/HF ratio were calculated. ResultszzWe found that ECP signifcantly increased the systolic and diastolic blood pressures in both stroke patients and controls. ECP decreased markedly the systolic and diastolic BPVs at VLF and LF and the TP, and the diastolic BPV at HF when compared with baseline. Te decreases in diastolic and systolic BPV reached 37.56% and 23.20%, respectively, at VLF, 21.15% and 12.19% at LF, 8.76% and 16.59% at HF, and 31.92% and 23.62% for the total TP in stroke patients, which did not difer from those in healthy controls. Te change in fow velocity on the contralateral side was positively correlated with the total TP systolic BPV change induced by ECP (r=0.312, p=0.035). ConclusionszzECP reduces the beat-to-beat BPV when increasing the blood pressure and cerebral blood fow velocity in ischemic stroke patients. ECP might be able to improve the clinical outcome by decreasing the beat-to-beat BPV in stroke patients, and this should be explored further in future studies.
Directed Evolution of Beta-galactosidase from Escherichia coli into Beta-glucuronidase
Xiong, Ai-Sheng,Peng, Ri-He,Zhuang, Jing,Liu, Jin-Ge,Xu, Fang,Cai, Bin,Guo, Zhao-Kui,Qiao, Yu-Shan,Chen, Jian-Min,Zhang, Zhen,Yao, Quan-Hong Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.3
In vitro directed evolution through DNA shuffling is a powerful molecular tool for creation of new biological phenotypes. E. coli $\beta$-galactosidase and $\beta$-glucuronidase are widely used, and their biological function, catalytic mechanism, and molecular structures are well characterized. We applied an in vitro directed evolution strategy through DNA shuffling and obtained five mutants named YG6764, YG6768, YG6769, YG6770 and YG6771 after two rounds of DNA shuffling and screening, which exhibited more $\beta$-glucuronidase activity than wild-type $\beta$-galactosidase. These variants had mutations at fourteen nucleic acid sites, resulting in changes in ten amino acids: S193N, T266A, Q267R, V411A, D448G, G466A, L527I, M543I, Q626R and Q951R. We expressed and purified those mutant proteins. Compared to the wild-type protein, five mutant proteins exhibited high $\beta$-glucuronidase activity. The comparison of molecular models of the mutated and wildtype enzymes revealed the relationship between protein function and structural modification.
Haodong Ge,Yunbo Shen,Yuquan Zhu,Yingzhao Xiong,Bing Yuan,Zongde Fang 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.11
For simulation and calculation of load-sharing behavior of planetary gear train by using the lumped mass method, an exact computational model of time-varying meshing stiffness of inner gear meshing pair with thin-walled sleeve was needed. Therefore, based on analysis of the flexible ring gear structure with thin-walled sleeve, an accurately model is proposed to obtain the time-varying internal meshing stiffness. Then, according to Newton's second law, a group of parametric differential equations of planetary gear system were derived, with which the load-sharing coefficient of the system was obtained. The load-sharing behavior experimental for the planetary gear train with five planetary gears and with flexible ring gear was designed, while the arrangement of the strain gauge was investigated and the test was performed under different working conditions. The test results show that the error of load sharing coefficient calculated by theory and experiment is less than 5 %.
Sulfonated multi-walled carbon nanotubes for the removal of copper (II) from aqueous solutions
Yuanyuan Ge,Zhili Li,Duo Xiao,Piao Xiong,Na Ye 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4
Sulfonated multi-walled carbon nanotubes (s-MWCNTs) was prepared from purified multi-walled carbon nanotubes (p-MWCNTs) by concentrated H2SO4 at elevated temperature. The structure was characterized by SEM, FTIR, Raman, XPS, and BET. It could be dispersed steadily in water at a dosage of 1.0 mg/mL for a week. The adsorption performance of s-MWCNTs toward Cu(II) was investigated including the effects of pH and ionic strength. Results indicated the adsorption was much dependent on pH but not on ionic strength. The adsorption capacity for Cu(II) was enhanced 58.9% via the sulfonation. Moreover, the adsorption mechanisms were carefully analyzed by Freundlich and D-R models.