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      • KCI등재

        Surface plasmon resonance-enhanced solar-driven photocatalytic performance from Ag nanoparticles-decorated Ti3+ self-doped porous black TiO2 pillars

        Guo Zhou,Haiyan Meng,Yan Cao,Xuejun Kou,Shuxiang Duan,Leilei Fan,Ming Xiao,Fangzhou Zhou,Zhenzi Li,Zipeng Xing 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.64 No.-

        The tiny Ag nanoparticles-uniformly decorated Ti3+ self-doped porous black TiO2 pillars (Ag-TPBTPs) are prepared, which show obvious surface plasmon resonance (SPR) and extend the photoresponse to visible light and near-infrared region (∼1500 nm). The Ag-TPBTPs exhibit excellent solar-driven photocatalytic activities by mineralizing of high-toxic 2,4-dichlorophenol (∼99%), which is three times higher than that of the pristine TiO2. The remarkable solar-driven photocatalytic performance can be ascribed to the porous pillars structure offering more surface active sites, the self-doped Ti3+ and SPR effect of Ag nanoparticles improving the utilization of solar light, and enhancing the spatial separation efficiency of photogenerated charge carriers.

      • KCI등재

        TiO2ecarbon nanotube composites for visible photocatalysts - Influence of TiO2 crystal structure

        Mu Yao Guo,Fangzhou Liu,Yu Hang Leung,Alan Man Ching Ng,Aleksandra B. Djurišić,Wai Kin Chan 한국물리학회 2013 Current Applied Physics Vol.13 No.7

        We investigated the influence of the crystal structure of TiO2 and the use of different TiO2 precursors on the properties and photocatalytic activity of carbon nanotube (CNTs)etitania composites. We found that the crystal structure and properties of starting TiO2 nanomaterial significantly affected the effect of CNTs incorporation on the photocatalytic activity under simulated solar and visible light illumination (simulated solar illumination with UV-blocking filter). In case of significant photocatalytic activity under visible light illumination (anatase TiO2), likely due to the presence of native defects, composites exhibited lower activity under visible illumination only, but higher activity under simulated solar illumination. The opposite trends were observed for P25 (anatase þ rutile) and rutile TiO2, where incorporation of CNTs resulted in a significant increase of photocatalytic activity under visible illumination. Thus, control over crystal structure and native defects is essential for the development of efficient visible light activated photocatalysts.

      • KCI등재

        Genomic and Transcriptomic Characterization Revealed the High Sensitivity of Targeted Therapy and Immunotherapy in a Subset of Endometrial Stromal Sarcoma

        Nan Kang,Yinli Zhang,Shichao Guo,Ran Chen,Fangzhou Kong,Shuchun Wang,Mingming Yuan,Rongrong Chen,Danhua Shen,Jianliu Wang 대한암학회 2023 Cancer Research and Treatment Vol.55 No.3

        Purpose The unique chromosomal rearrangements of endometrial stromal sarcoma (ESS) make it possible to distinguish high-grade ESS (HGESS) and low-grade ESS (LGESS) from the molecular perspective. Analysis of ESS at the genomic and transcriptomic levels can help us achieve accurate diagnosis of ESS and provide potential therapy options for ESS patients.Materials and Methods A total of 36 ESS patients who conducted DNA- and/or RNA-based next-generation sequencing were retrospectively enrolled in this study. The molecular characteristics of ESS at genomic and transcriptomic levels, including mutational spectrum, fusion profiles, gene expression and pathway enrichment analysis and features about immune microenvironment were comprehensively explored.Results <i>TP53</i> and <i>DNMT3A</i> mutations were the most frequent mutations. The classical fusions frequently found in <i>HGESS</i> (<i>ZC3H7B-BCOR</i> and <i>NUTM2B-YWHAE</i>) and LGESS (<i>JAZF1-SUZ12</i>) were detected in our cohort. <i>CCND1</i> was significantly up-regulated in HGESS, while the expression of <i>GPER1</i> and <i>PGR</i> encoding estrogen receptor (ER) and progesterone receptor (PR) did not differ significantly between HGESS and LGESS. Actionable mutations enriched in homologous recombination repair, cell cycle, and phosphoinositide 3-kinase/AKT/mammalian target of rapamycin pathways were detected in 60% of HGESS patients. Genes with up-regulated expression in HGESS were significantly enriched in five immune-related pathways. Most HGESS patients (85.7%) had positive predictors of immunotherapy efficacy. Moreover, immune microenvironment analysis showed that HGESS had relatively high immune infiltration. The degree of immune infiltration in HGESS patients with <i>ZC3H7B-BCOR</i> fusion was relatively higher than that of those with <i>NUTM2B-YWHAE</i> fusion.Conclusion This study investigated the molecular characteristics of ESS patients at the genomic and transcriptomic levels and revealed the potentially high sensitivity of targeted therapy and immunotherapy in a subset of HGESS with specific molecular features, providing a basis for guiding decision-making of treatment and the design of future clinical trials on precision therapy.

      • KCI등재

        Degradation Mechanisms of Chloride Contaminated Cast-in-Situ Concrete Partially Exposed to Magnesium-Sulfate Combined Environment

        Gaowen Zhao,Yiqi Hu,Shaomin Li,Zhuo Wang,Mengzhen Guo,Fangzhou Han,Haoran Wang 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.2

        Cast-in-situ concrete suffers complicated working conditions in sulfate-rich saline soil areas. Sulfate-magnesium combined attack can be encountered in heavy saline or salty lake areas. This study investigated the degradation process and corresponding mechanisms of cast-in-situconcrete, contaminated by chlorides, partially exposed to sulfate-magnesium combined corrosiveenvironments. Concrete samples were cast and partially immersed in the pre-prepareddistilled water, sulfate or sulfate-magnesium mixed solutions for 12 months. Physical andmechanical properties of concrete samples were continuously measured and recorded duringthe immersion. Sulfate concentration in different depths were measured by chemical titration. SEM, XRD, TG/DTG tests were conducted to analyze the microstructural and mineral propertychanges after corrosion for concrete suffered different corrosion conditions. Results show thatpartially immersed concrete encounters both chemical and physical degradation induced bycorrosive sources. Concrete contaminated by chlorides obviously shows weaker resistanceagainst sulfate attack and the strength development is also negatively affected. Magnesium inthe environments reduces the early strength of partially immersed cast-in-situ concrete whileenhancing the sulfate resistance ability in the later corrosion stage. Magnesium limits thenegative effect of contaminated chlorides on the partially immersed cast-in-situ concrete. Performance of cast-in-situ concrete is different from precast concrete when encounteringdifferent corrosive sources, and thus more attention should be paid on the degradation ofcast-in-situ concrete structures induce by aggressive environments.

      • KCI등재

        Experimental Study and Degradation Analysis on Interfacial Shear Modulus of Steel and Steel Fiber-Reinforced Concrete Composite Structure

        Kai Wu,Shiyuan Qian,Huiming Zheng,Yukai Zhou,Fangzhou Guo 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.8

        To address the problems of mutual interference between shaped steel and reinforcement bars and the difficulty of concrete pouring in the construction of steel-reinforced concrete (SRC) composite structure, the steel and steel fiber-reinforced concrete (SSFRC) composite structure without rebars was proposed. Bond behavior between the shaped steel and steel fiber reinforced concrete is the basis to ensure two kinds of materials work together. 20 square specimens were designed and tested by push-out test to study the bond performance and shear modulus of the interface between the shaped steel and steel fiber reinforced concrete. The effects of steel fiber ratio (ρsf), embedded length (Le), and concrete cover thickness (Css) on the interfacial shear modulus (G) were analyzed quantitatively. The degradation law of G was studied by defining the degradation variable of interfacial shear modulus (Da). The results show that the increase of ρsf contributes to the ascent in G, and the loading end displacement (D) at the end of degradation related to G also increase. With the rise of Le, the value of Gdecreases gradually and the D becomes larger when G starts to deteriorate. In addition, there is a positive correlation between G and Css. Besides, the higher Css leads to a slower degradation process of G.

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