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UAV와 YOLOv5를 활용한 해안 표착 쓰레기 탐지 및 분포현황 시각화
도예빈(Ye-Been Do),김보람(Bo-ram Kim),박미소(Mi-so Park),오세윤(Se-yun Oh),김재원(Jae-won Kim),윤홍주(Hong-Joo Yoon) 한국생태공학회 2022 한국생태공학회지 Vol.9 No.1
Marine debris is defined as a substance that is intentionally or inadvertently left on the coast or is harmful to the marine environment due to inflow and discharge. It can be divided into floating debris, sedimentary debris, and beach litter depending on its location. In this study, UAV and YOLOv5x were used to detect beach litter economically and efficiently. The research area is the coastal area of Geoje-si, Gyeongsangnam-do, and Gadeokdo, Gangseo-gu, Busan, and beach litter detection research was conducted by collecting images by altitude and characteristics of UAVs. When detecting coastal drifting garbage by altitude, the accuracy was the highest at an altitude of 0.727, and the detection accuracy of PET was 0.776 when detecting beach litter by type. After that, as a result of visualizing the detection results, it was possible to show the spatial distribution status of beach litter.
Yoon, Hyonok,Kim, Do-Sung,Lee, Geum-Hwa,Kim, Ji Ye,Kim, Diana H,Kim, Kee-Won,Chae, Soo-Wan,You, Wan-Hee,Lee, Yong Chul,Park, Seoung Ju,Kim, Hyung-Ryong,Chae, Han-Jung Pharmaceutical Society of Great Britain 2009 Journal of pharmacy and pharmacology Vol.61 No.11
<P>OBJECTIVES: This study tested whether sodium para-amino salicylic dihydrate, an antibacterial drug for tuberculosis, could block manganese-induced apoptosis in SK-N-MC neurons. METHODS: Cell viability, Hoechst staining, dichlorofluorescin diacetate analysis for reactive oxygen species measurement, and immunoblotting were performed. KEY FINDINGS: In vitro, manganese chloride significantly decreased the viability of SK-N-MC cells, accompanied by apoptotic features such as changes in nuclear morphology. Sodium para-amino salicylic dihydrate inhibited these apoptotic characteristics through reducing intracellular reactive oxygen species generation, protecting mitochondrial membrane potential and caspase-3 activation. CONCLUSIONS: Sodium para-amino salicylic dihydrate inhibits manganese-induced apoptosis in neurons and may reduce manganese-mediated neurodegeneration.</P>
( Ye-eun Kim ),( Seong-eun Ko ),( Da-eun Sa ),( Ji-eun Lee ),( Se-yoon Jeon ),( Do-seon Lim ) 한국치위생과학회 2020 치위생과학회지 Vol.20 No.4
Background: This study tries to compare and analyze the removal effect of dental plaque of general dentifrice and pregnant women’s dentifrice and quantify the results to provide basic data so that consumers can make reasonable choices when purchasing dentifrice, and also increase interest in the dental plaque. Methods: After forming a dental plaque (carbohydrate porridge) on the labial surface of the bovine teeth, a disclosing agent was applied. Then the same experimenter brushed the surface of the bovine teeth using an electric toothbrush and took photographs using a DSLR camera. Thereafter, the residual amount of dental plaque was analyzed using the ImageJ program, and SPSS 26.0 was used for statistical processing. Results: The average residual amount of dental plaque using the general dentifrice was 11.71% for Perio, 9.45% for Cliden, and 8.47% for 2080, and the average residual amount for the three types was approximately 9.88%. The average residual amount of dental plaque of pregnant women’s dentifrice was 13.95% for Jeninmothers, 12.53% for Tntnmoms, and 12.63% for Mommiracle, and the average residual amount of the three types was approximately 13.04%. On comparing the average residual amount of dental plaque between general and pregnant women’s dentifrices, it was observed to be 3.16% higher for the latter. However, the results were not statistically significant. Conclusion: According to the research results, there was no significant difference in removal effects of general dentifrice and pregnant women’s dentifrice. In addition, when a pregnant woman uses the right toothbrushing method with pregnant women’s dentifrice, it can prevent or inhibit the progression of the gestational periodontal disease. Therefore, we recommend pregnant women to use pregnant women’s dentifrices.
( Ye Sol Bak ),( Sun Young Ham ),( Baatartsogt O ),( Seung Hyun Jung ),( Kang Duk Choi ),( Tae Young Han ),( Il Young Han ),( Do Young Yoon ) 한국응용생명화학회(구 한국농화학회) 2014 Journal of Applied Biological Chemistry (J. Appl. Vol.57 No.2
A5E is complex of several medicinal herb ethanol extracts. The aim of this study is investigating the anticancer effect for non-small cell lung cancer. The antitumor effects of A5E on NCI-H460 were examined by regulation of cell proliferation, apoptosis, cell cycle arrest, mitochondrial membrane potential (Δψm), and apoptosis-related protein. Cell proliferation was measured by MTS assay. Apoptosis induced by A5E was confirmed by Annexin V-fluorescein isothiocyanate (FITC)/Propidium Iodide (PI) staining, and cell cycle arrest was measured by PI staining. NF-κB translocation was detected by immunofluorescence and MMP (Δψm) was measured by JC-1 staining. The expression of extrinsic pathway molecules such as FasL and FADD were elevated, and procaspase-8 was processed by A5E. In addition, intrinsic pathway related molecules were altered. The Bcl-2 and Bcl-xl levels decreased, Bax increased, and cytochrome C was released. In addition, the mitochondrial membrane potential collapsed, and caspase-3 and poly-(ADP-ribose) polymerase were processed by A5E. Moreover, A5E affected the cellular survival pathway involving phosphatidylinositol 3-kinase (PI3K)/Akt and NF-κB. PI3K and Akt were downregulated, also NF-κB expression was decreased, and nuclear translocalization was inhibited by A5E. These results suggested that A5E delays proliferation, inhibit cell cycle progression and induce apoptosis in human lung cancer cell. We conclude that A5E is a potential anticancer agent for human lung carcinoma.
Ye, Byoung Seok,Seo, Sang Won,Lee, Yunhwan,Kim, Seong Yoon,Choi, Seong Hye,Lee, Young Min,Kim, Do Hoon,Han, Hyun Jeong,Na, Duk L.,Kim, Eun-Joo S. Karger AG 2012 DEMENTIA AND GERIATRIC COGNITIVE DISORDERS Vol.34 No.3
<P>Abstract</P><P><B><I>Background:</I></B> Amnestic mild cognitive impairment (aMCI) is regarded as a prodromal stage of Alzheimer’s disease (AD). Given that patients with early-onset AD (EOAD) and with late-onset AD (LOAD) are known to have different clinical courses, symptoms and neuroimaging findings, early-onset (EOMCI) and late-onset aMCI (LOMCI) might be expected to have similar differences as EOAD versus LOAD. <B><I>Methods:</I></B> Our study involving 425 patients with aMCI (124 EOMCI, 301 LOMCI), who were followed for around 1.5 years, and 958 normal control subjects (NC) investigated neuropsychological characteristics and prediction of progression to AD in patients with EOMCI versus LOMCI. Neuropsychological scores were compared between EOMCI, LOMCI and NC with analyses of covariance controlling age, gender, education and disease duration. The risk of AD conversion was evaluated by Cox proportional hazard analyses. <B><I>Results:</I></B> The baseline neuropsychological performances were comparable between EOMCI and LOMCI. Visuospatial memory for EOMCI and verbal memory scores for LOMCI were significant predictors of AD conversion. <B><I>Conclusion:</I></B> Our study indicates that EOMCI with visuospatial memory impairment, which implies underlying right predominant pathology, and LOMCI with poor verbal memory, which suggests underlying left predominant pathology, are individual conditions at an increased risk of conversion to AD.</P><P>Copyright © 2012 S. Karger AG, Basel</P>
Safety and efficacy of 10-fraction hypofractionated radiation therapy for non-small cell lung cancer
Ye Jin Yoo,Su Ssan Kim,Si Yeol Song,Jong Hoon Kim,Seung Do Ahn,Sang-wook Lee,Sang Min Yoon,Young Seok Kim,Jin-hong Park,Jinhong Jung,Eun Kyung Choi 대한방사선종양학회 2021 Radiation Oncology Journal Vol.39 No.3
Purpose: To investigate the safety and efficacy of hypofractionated radiation therapy (HFRT) in patients with non-small cell lung cancer who are unfit for surgery or stereotactic body radiation therapy (SBRT) at our institution. Materials and Methods: From May 2007 to December 2018, HFRT was used to treat 68 lesions in 64 patients who were unsuitable for SBRT because of central tumor location, large tumor size, or contiguity with the chest wall. The HFRT schedule included a dose of 50–70 Gy delivered in 10 fractions over 2 weeks. The primary outcome was freedom from local progression (FFLP), and the secondary endpoints included overall survival (OS), disease-free survival, and toxicities. Results: The median follow-up period was 25.5 months (range, 5.3 to 119.9 months). The FFLP rates were 79.8% and 67.8% at 1 and 2 years, respectively. The OS rates were 82.8% and 64.1% at 1 and 2 years, respectively. A larger planning target volume was associated with lower FFLP (p = 0.023). Dose escalation was not associated with FFLP (p = 0.964). Four patients (6.3%) experienced grade 3–5 pulmonary toxicities. Tumor location, central or peripheral, was not associated with either grade 3 or higher toxicity. Conclusion: HFRT with 50–70 Gy in 10 fractions demonstrated acceptable toxicity; however, the local control rate can be improved compared with the results of SBRT. More studies are required in patients who are unfit for SBRT to investigate the optimal fractionation scheme.