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Nowadays, NAND flash memory has become major storage in building portable information devices because of its non-volatility, shock-resistance, energy-friendly, and robust access time for read operations. One drawback of the flash memory file system is how to provide efficient roll back or crash recovery. This type of observation motivates our research on the investigation of crash recovery of flash-memory file systems. In this paper, we introduced a concept of shadow paging and presented a crash recovery scheme for log-based file systems over flash memory using shadow paging. In this paper a scheme is proposed for the crash recovery for log-based file systems over flash memory using shadow paging. We have also described the initialization and mounting of flash memory and we have given brief background on flash memory management like wear leveling, flash translation layer (FTL) and flash file system such as FAT/FAT32, ExFAT, JFFS2, LogFS and YAFFS. In addition, we have improved the Wear-Levelling of Garbage Collection Algorithms such as CATA, Greedy, and Cost Benefit by improving the flash memory device information.
Biological screening of the natural products from Dalbergia oliveri identified that (6aR,11aR)-3,8-dihydroxy-9-methoxypterocarpan and (3R)-7,2′-dihydroxy-4′,5′-dimethoxyisoflavanone significantly increased the proliferation of dermal papilla cells and subcutaneous injection of these compounds induced the anagen of hair cycle in animal models. These interesting biological activities led us to design a practical synthetic route to these natural products for further pharmacological evaluation. Here we report the first total syntheses of naturally occurring pterocarpan ((6aR,11aR)-3,8-dihydroxy-9-methoxypterocarpan), isoflavan ((3R)-5′-methoxyvestitol), and isoflavanone ((3R)-7,2′-dihydroxy-4′,5′-dimethoxyisoflavanone) in a racemic form. A mild ZnCl2-mediated [3 + 2] annulation method was utilized with chromenes and 2-methoxy-1,4-benzoquinone to construct a pterocarpan framework in a one-pot manner. O-methylation and reductive cleavage of the benzylic C─O bond afforded 5′-methoxyvestitol, which was transformed to isoflavanone, 7,2′-dihydroxy-4′,5′-dimethoxyisoflavanone, via a three-step sequence including DDQ-mediated benzylic oxidation.
Dileep Chandran Ramachandran,Siva Prasad Murugan,Ji-Ung Kim(김지웅),Jun Oh Moon(문준오),Chang Hoon Lee(이창훈),Seung Jin Jung(정승진),Sang Hoon Jeong(정상훈),Jun Ho Chung(정준호),Yeong-Do Park(박영도) 대한용접·접합학회 2018 대한용접학회 특별강연 및 학술발표대회 개요집 Vol.2018 No.11
This paper proposes a task assignment based on auction algorithm for a decoy mission using multiple UAVs which can hover against anti-ship missiles. An optimal deployment direction of decoys are also decided based on the cost function that is calculated with the expected signal power of a seeker and decoy, the distance between them, and fuel availability of the decoys. A simple kinematics is considered to generate two-dimensional motions of anti-ship missiles and a target ship. Numerical simulations are conducted under a visualization environment and validate the performance of the proposed algorithm. A parametric study is also conducted for the decoy mission with multiple missiles and decoys. Lastly, non-linear simulations for ducted fan Unmanned Aerial vehicles (UAVs) are performed to evaluate the feasibility of the proposed high-level task assignment comment for the decoy mission.
The corrosion behavior of fusion zones (FZ-1: 5.39 Mg–0.66Mn, FZ-2: 5.49 Mg–0.35Mn, and FZ-3: 5.72 Mg–0.32Mn)of AA5083 alloy welded with high Mg-containing Al–Mg filler wires has been systematically investigated. An extensivemicrostructural characterization was performed to evaluate the localized corrosion properties of the fusion zones. Thepotentiodynamic polarization test and salt spray test showed that the corrosion resistance decreases with increasing Mg content,therefore, the corrosion resistance of FZ-3 is lower than that of the FZ-1 and FZ-2. The electron microscopic analysisafter intermittent corrosion test revealed that the eutectic β-phase (Al3Mg2) was responsible for the initiation of corrosion. The corrosion behavior of each microstructural constituents was related to the dissolution potentials of the correspondingmicrostructures; hence, it forms galvanic couple with the Al matrix. Moreover, high Mg content in the filler wire lead to theformation of additional β-phase in the fusion zone. However, intermetallics such as Al6(Fe,Mn) and Mg2Siwere significantonly during the later stages of corrosion.
Photothermal therapy (PTT) is one of recently emerging anticancer treatment modalities that involve the use of laser and photosensitizers. To fully explore the therapeutic potential of PTT, it is critical to deliver photosensitizers to tumors specifically. Maltodextrin is a hydrophilic polysaccharide consisting of D-glucose units and has been used as a pharmaceutical excipient because of its excellent biocompatibility. IR820 is a derivative of indocyanine green (ICG), a clinically used imaging agent and has potential as a photosensitizer for PTT. However, the clinical translation of IR820 has been limited by its lack of cancer targeting ability and poor stability in physiological environments. In this study, we hypothesized that IR820-conjugated maltodextrin (MDir) preferentially accumulates in tumors and serves as photothermal agents. Combination of MDir and near-infrared (NIR) laser irradiation significantly increased the temperature, leading to photothermal-mediated apoptosis of cancer cells. In a mouse xenograft models, MDir preferentially accumulated in tumors and induced almost complete thermal ablation of tumors upon NIR laser irradiation. Based on its tumor targeting ability, photothermal conversion efficiency and excellent biocompatibility, we anticipate that MDir holds great translational potential as a fluorescence imaging-guided photothermal agent for cancer treatment.