Chromatography-free Purification of Paclitaxel from Taxus chinensis by Three-step Tandem Cavitation Fractional Precipitation

Dayeon KANG,jinhyun KIM 한국생물공학회 2023 한국생물공학회 학술대회 Vol.2023 No.10

Safety of COVID-19 Vaccination During Pregnancy and Lactation: A VigiBase Analysis

Kang Dayeon,Choi Ahhyung,Park Suneun,Choe Seung-Ah,Shin Ju-Young 대한의학회 2024 Journal of Korean medical science Vol.39 No.1

Background: There is limited evidence on the safety of coronavirus disease 2019 (COVID-19) vaccination during pregnancy and lactation. Thus, we aimed to evaluate the association between COVID-19 vaccination during pregnancy and lactation and reporting risk of adverse pregnancy or lactation outcomes. Methods: Using VigiBase, we performed a disproportionality analysis with case/non case design. Cases were defined based on the Standardized MedDRA Queries (SMQs) of “pregnancy and neonatal topics” and non-cases were defined as all other adverse events. We included all reports with COVID-19 vaccines as the suspected cause. Using the full database as the comparators, reporting odds ratios (RORs) with 95% confidence intervals (CIs) were estimated by logistic regression while adjusting for maternal age. Infants’ age and sex were additionally adjusted in analyzing the risk of COVID-19 vaccination during lactation. Results: We identified 10,266 and 6,474 reports with the SMQ of “pregnancy and neonatal topics” associated with COVID-19 vaccines during pregnancy and lactation, respectively. No significant RORs of adverse pregnancy outcomes associated with COVID-19 vaccines during pregnancy were observed; however, “functional lactation disorders” showed significant disproportionality during lactation with adjusted ROR of 1.48 (95% CI, 1.21–1.79). Further analysis that analyzed “functional lactation disorders” at a preferred term level, showed higher ROR in mastitis (2.76 [95% CI, 1.45–5.27]). Conclusion: Overall, we did not observe a positive association between COVID-19 vaccination during pregnancy and risk of reporting adverse pregnancy outcomes. However, we found a significant disproportionate reporting association between COVID-19 vaccination during lactation and “functional lactation disorders”, specifically mastitis. Continuous surveillance is warranted to confirm the safety of COVID-19 vaccine during pregnancy and lactation.

A Study on the Recent Content and Method for Foreign Language Education of North Korea in Higher Education

( Dayeon Kang ) 이화여자대학교 통일학연구원 2020 Journal of peace and unification Vol.10 No.3

This research aims to examine how the recent higher education curriculum in Kim Jong - un’s North Korea has reflected its educational policy to strengthen foreign language edu- cation and identify the concrete content and method for this. A North Korean period ical, Higher Education , is referred to as the text which includes instructions from the supreme leader, explanations of the party’s education policies, and the content and method that the higher education pursues. The foreign language education in North Ko rea is primarily for the elite . In addition, the authority also aims to raise college students as the guardians of its political regime by nurturing their collective consciousness alongside language educa-tion, and, for doing so, they use various media outl ets as the means to provide the elite students with advanced education.

Ultrasonic Cavitation Bubble-assisted Adsorption for the Recovery of Paclitaxel from the Plant Cell Cultures of Taxus chinensis Using Diaion HP-20

Dayeon KANG,Hyunji OH,Jinhyun KIM 한국생물공학회 2022 한국생물공학회 학술대회 Vol.2022 No.9

중학생의 정신력 척도의 타당도 및 신뢰도 탐색

강다연 ( Kang Dayeon ),안도희 ( Ahn Doehee ) 인하대학교 교육연구소 2016 교육문화연구 Vol.22 No.5

본 연구에서는 Clough 외(2002)가 운동선수들을 대상으로 개발한 정신력 척도가 청소년에게도 적용가능한지를 탐색해보기 위해 해당 척도를 청소년들에게 적합하도록 번안하여 이에 대한 타당도와 신뢰도를 탐색하였다. 이를 위해 서울(강북, 강남, 강서)소재 중학교에 재학 중인 중학생593명을 대상으로 검사를 실시하였다. Clough 외(2002)의 정신력 척도는 `도전`, `책임`. `삶의 통제`, `감정 통제`, `능력에 대한 확신`, `대인관계에 대한 확신`으로 총 6개 요인 48개 문항으로 구성되어 있으며, 이에 대한 타당도를 탐색하기 위해 탐색적 요인분석과 확인적 요인분석을 수행한 결과, 총 5개 하위 요인, 33개 문항이 최종 도출되었다. 각 하위요인에 해당하는 문항 내용들을 살펴본 후, 이에 부합되는 요인명(도전, 책임, 능력에 대한 확신, 적극적 감정통제, 소극적 감정통제)을 부여하였다. 둘째, 최종 도출된 5개 하위 요인들에 대한 신뢰도(Cronbach의 α)는 .584∼.863으로 나타났다. 셋째, 수렴 타당도 검증을 위해 정신력 척도의 5개 하위 요인들과 관련 변인들(학업스트레스, 자아존중감, 삶의 만족도, 낙관성) 간의 상호상관을 살펴 본 결과, 정신력 척도와 이들 변인들과 유의한 상관을 보였다. 따라서 정신력 척도의 수렴 타당도가 확보되었음을 알 수 있다. 이러한 본 연구결과를 통해 타당도가 입증된 정신력 척도는 중학교 학생들의 정신력을 진단하고, 이들의 정신력 함양을 위한 기초자료로 활용될 수 있을 것으로 기대된다. This study investigates the validity and reliability of the mental toughness scale(MTS) for middle school students. The subjects were 593 middle school students in Seoul, Korea. The MTS, which was originally developed by Clough et al.(2002) for athletes, was revised to be suitable for middle school students and were applied to them. The MTS scale was verified and refined through exploratory and confirmatory factor analyses. As a result, the MTS scale consisted of five factors(i.e., challenge, commitment, confidence in ability, active emotion control, and passive emotion control) with 33 items. Convergent validity was supported through correlations among educational stress, depression, life satisfaction, self-esteem, and optimism. Implications of this study were discussed in terms of educational settings.

단계적 딥러닝 모델과 드론 이동경로계획 알고리즘을 사용한 포도 등급 판별 시스템

강다연(Dayeon Kang),김지수(Jisoo Kim),김도연(Doyeon Kim),김혜진(Hyejin Kim),채기준(Kijoon Chae) 한국정보과학회 2022 한국정보과학회 학술발표논문집 Vol.2022 No.06

정보보안정책 준수가 정보보안능력 및 행동에 미치는 영향 분석

강다연(Dayeon Kang),장명희(Myunghee Chang) 한국항만경제학회 2014 韓國港灣經濟學會誌 Vol.30 No.1

최근 발생한 고객정보유출사고는 조직의 정보보안 강화에 대한 관심과 전담조직의 중요성을 고조시키고 있다. 이에 따라 기업들은 정보보안 강화를 위해 정보보안정책을 마련하고 있으며, 조직구성원들로 하여금 보안정책을 준수하도록 권고하고 있다. 해운항만 조직에서도 정보보안을 위해 정보보안정책을 체계화시키고 조직구성원들의 정보보안능력과 정보보안행동을 평가할 필요성이 있다. 본 연구의 목적은 해운항만조직 구성원들을 대상으로 정보보안정책 준수 정도가 정보보안능력과 정보보안행동에 미치는 영향을 분석하는데 있다. 분석결과, 먼저 해운항만조직 구성원의 정보보안정책 준수에 영향을 미치는 요인으로 정보보안규범과 정보보안교육을 확인할 수 있었고, 정보보안처벌은 정보보안정책 준수에 유의한 영향을 미치지 않는 것으로 분석되었다. 해운항만조직 구성원의 정보보안정책 준수정도는 정보보안능력과 정보보안행동에 유의한 영향을 미치는 결과를 확인할 수 있었다. Recent accidents of customer information leakage increase the necessity of information security for organization and the importance of information security team for it. To strengthen information security, organizations make information security policy and ask the members to comply with it. In this regard, maritime organization also needs to structure information security policy and examine its ability and behavior. The purpose of this study is to analyze the effects of compliance with information security policy on the ability and behavior of workers in shipping and port organization. The results of investigation show that information security education and norm affect compliance with information security of the workers. On the contrary, the punishment of information security is insignificant. It is shown that the degree of compliance with information security significantly affects its ability and behavior of the workers in shipping and port organization.

해운항만조직 구성원들의 정보보안정책 준수에 영향을 미치는 요인

강다연(Dayeon Kang),장명희(Myunghee Chang) 한국항만경제학회 2012 韓國港灣經濟學會誌 Vol.28 No.1

정보기술의 발전은 기업에게 많은 이익을 가져다주었지만, 정보유출이라는 심각한 문제를 야기하고 있다. 이에 따라 기업들은 정보보안을 위해 정보보안정책을 수립하고 조직구성원들이 정보보안정책을 준수할 것을 요구하고 있다. 본 연구에서는 해운항만조직 구성원들의 정보보안정책 준수에 영향을 미치는 요인들을 실증분석 하기 위해 정보보안인식, 정보보안태도, 자기효능감, 규범신념, 사회적 영향들을 영향요인으로 선정하였다. 분석결과에 따르면, 해운항만조직 구성원들의 정보보안인식과 정보보안태도와의 관계는 긍정적으로 나타났으며, 정보보안태도와 정보보안정책 준수와의 관계도 긍정적으로 나타났다. 그리고 자기효능감과 정보보안정책 준수와의 관계, 사회적 영향과 정보보안정책 준수의 관계도 긍정적으로 나타났다. 하지만 규범신념과 정보보안정책 준수와의 관계는 유의하지 않은 것으로 분석되었다. 본 연구의 결과는 정보유출문제가 발생할 가능성이 큰 해운항만조직의 구성원들이 정보보안정책의 준수사항을 어느 정도로 받아들이는 지를 확인함으로써 해운항만조직에서 정보보안과 관련된 정책을 수립하는데 기반을 제공할 것으로 기대한다. Advances in information technology has brought many benefits to businesses, but at the same time, businesses are facing serious problems caused by its use such as information leakage. In order to cope with problems, companies have established information security policies, demanding workers of a company to be compliant with the policies. This study proposes a research model that includes information security awareness, information security attitude, self-efficacy, standard belief and social influences as factors that affect the compliance of information security policy among the workers of shipping and port organization. The results of this study showed that there was a positive relationship not only between the information security awareness and the information security attitude, but also between the information security attitude and the information security policy among the workers of shipping and port organization. It was also found that there was a positive relationship between the self-efficacy and the compliance of information security policy, and between the social influence and the compliance of information security policy. However, there was no meaningful relationship between the standard belief and the compliance of information security policy. This study examined to what extent the workers of shipping and port organization that have a high possibility of the information leakage were compliant with the information security policy. The findings will contribute to organizations of shipping and port who attempt to establish strategies related to information security.

맥문동 열수 추출물이 Poly I:C를 처리한 폐암세포주의 사멸 및 염증성 사이토카인 발현에 미치는 영향

강다연 ( Dayeon Kang ),조남준 ( Namjoon Cho ),렌친핸드 ( Gereltuya Renchinkhand ),이보희 ( Bo-hee Lee ),김은미 ( Eun-mi Kim ),남명수 ( Myoung Soo Nam ),김기광 ( Keekwang Kim ) 대한본초학회 2021 大韓本草學會誌 Vol.36 No.1

Objectives : Virus infection through the respiratory tract causes various inflammatory diseases such as pneumonia, cystic fibrosis, and obstructive pulmonary disease, causing enormous social damage. Therefore, it is very important to develop a treatment and prevention of infectious diseases. In this study, we investigated the effect of water extracts of Liriope muscar i (WELM), known to improve lung function, on the inflammatory response of lung carcinoma cell line A549 cells induced by the viral double stranded RNA mimetic Polyinosinic:polycytidylic acid (Poly I:C). Methods : The cell viability by WELM treatment was analyzed using MTS assay in A549 cells. After inducing an inflammatory response to WELM-treated A549 cells with Poly I:C, the degree of apoptosis was confirmed through bright field microscopy. Interferon beta (IFN-β) mRNA expression level in A549 cells was analyzed by quantitative reverse transcription PCR (qRT-PCR). Results : WELM treatment has no significant effect on cell viability of A549 cells. We confirmed that pre-treatment of WELM effectively reduces the Poly I:C-induced apoptotic cell death in A549 cells. In addition, it was confirmed that the mRNA expression level of IFN-β, a pro-inflammatory cytokine increased by Poly I:C treatment, was significantly suppressed by WELM treatment in A549 cells. Conclusions : These results provide the evidence that WELM is effective at inhibiting inflammation on respiratory viral infections and suggest that Liriope muscari might be a valuable natural substance in the prevention and treatment of infectious diseases.

한국과 일본의 FTA 경제적 효과에 관한 비교 분석

강다연 ( Dayeon Kang ),전영서 ( Youngseo Jeon ) 한국국제경제학회 2015 국제경제연구 Vol.21 No.3

본 연구는 한국과 일본의 128개 교역국에 대한 1990년부터 2013년까지 패널 자료를 통해 FTA 발효로 인한 양국의 교역효과를 통계적으로 비교 분석하고자한다. 중력모형을 바탕으로 이중차이(DD) 추정법을 통해 양국의 FTA 발효 효과를 개별 시도하고, 삼중차이(DDD) 추정을 통해 한국과 일본의 지역적 차이를 고려한 FTA 발효 효과를 비교한다. 분석 결과 첫째, 양국의 교역은 교역국 간의 GDP와 1인당 GDP에 비례하고, 거리에 반비례하는 중력모형의 전제와 동일하며 둘째, 거리 변수의 영향은 한국보다 일본이 더 많이 받으며 셋째, 환율 변수는 한국과 일본의 교역량에 대하여 각기 다른 부호로 추정되어 수출의존형인 한국의 교역구조와 역수입이 우세한 일본의 교역 특성을 의미하고 넷째, FTA 발효 효과를 나타내는 이중차이 추정결과 한국과 일본 모두 FTA 발효국이 준비국에 비해 교역증진 효과가 있는 것으로 나타났으며 마지막으로, 삼중차이 추정결과 한국의 FTA 발효 효과는 일본에 비하여 약 0.77%만큼 교역증진효과가 있음을 보인다. 이는 이제껏 제한적인 일본의 FTA 정책과 달리 FTA 발효국이 많고 주요 교역국과 FTA 발효가 이루어진 동시다발적 성격의 FTA 체결을 이루어온 한국의 FTA 추진 정책에 대한 긍정적인 실효성을 의미한다. This study shows the economic effects of Korea and Japan FTA through the panel gravity model and DD (Difference in Difference), DDD (Difference in Difference in Difference) estimator. The data structure is estimated for exports and imports using an annual panel data set covering 128 countries for 1990~2013. According to the results of the analysis, firstly, the result shows Korea and Japan trade similar to the basic gravity model. It means GDP and GDP per capital have positive relationship with trade volumes but distance has negatively significant impact on it. Secondly, in order to control the specificity of Korean and Japanese, we need exchange rate variable which has a positively significant impact on Japan trade while Korea trade has negatively significant impact on it. It shows the ratio of import is higher than export in the Japan’s total trade volumes but Korea trade has the opposite effects. Thirdly, as a result of the DD estimator, there is a promotion effects on the trade when we compare the FTA conclusion to preparing the FTA with Korea and Japan. Especially, the DDD estimator result reflects Korea FTA effect is more effective than Japan FTA.