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      • KCI등재

        An approach for deformation modulus mechanism of super-high arch dams

        Bangbin Wu,Jingtai Niu,Huaizhi Su,Meng Yang,Zhongru Wu,Xinbo Cui 국제구조공학회 2019 Structural Engineering and Mechanics, An Int'l Jou Vol.69 No.5

        The reservoir basin bedrock produced significant impact on the long-term service safety of super-high arch dams. It was important for accurately identifying geomechanical parameters and its evolution process of reservoir basin bedrock. The deformation modulus mechanism research methods of reservoir basin bedrock deformation modulus for super-high arch dams was carried out by finite element numerical calculation of the reservoir basin bedrock deformation and in-situ monitoring data analysis. The deformation modulus inversion principle of reservoir basin bedrock in a wide range was studied. The convergence criteria for determining the calculation range of reservoir basin of super-high arch dams was put forward. The implementation method was proposed for different layers and zones of reservoir basin bedrock. A practical engineering of a super-high arch dam was taken as the example.

      • Initial Position Detection of Permanent Magnet Synchronous Machines with Self-Tuning Extended State Observer

        Yawei Wu,Yifan Cui,Ronggang Ni,Shuxin Nie,Xinzhen Wu 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

        The performance of the initial rotor position detection of Permanent Magnet Synchronous Machines (PMSMs) at standstill depends much on the position observer. In this paper, the Extended State Observer (ESO) is compared with the traditional Proportional Integration (PI) observer adopting the rotating high frequency voltage injection algorithm, and the observer parameter design method is derived based on the bandwidth analysis of the close-loop transfer function. Experiments are carried out on a 3 kW PMSM prototype for verifications.

      • KCI등재

        中国公司法之司法续造的实证分析:困惑与出路

        무취단(Wu Cui Dan)(武翠丹) 원광대학교 법학연구소 2016 圓光法學 Vol.32 No.2

        基于公司法时滞性、技术性、自治性立法层面的障碍, 《公司法》无法预期涵摄后出现的社会关系是必然的, 这也必将致使法律漏洞的产生, 《公司法》这个无法弥补的先天遗憾, 却促使司法实践中不得不在一定程度上引入法官的主观能动性, 法官在公司法立法层面日趋完善而司法层面实施弱化的大背景之下, 仍然依靠三段论的推理模式解决公司 法律规制阙如的司法困惑显然力不从心。司法不得不针对公司法律规则的不完备性进行续造, 以期弥补公司法理论与公司法实务之间的缝隙。只是司法续造的过程中应当注意防守司法介入的底限, 不仅不能威胁公司自治精神的存在, 而且也不能窒息公司自治的功能。文章在分析司法续造影响性因素的基础之上, 为解决“同案不同判”的冲突, 走出司法能动性与成文法稳定性的两难困境, 为填补公司法律漏洞提供统一的司法解决方案, 提出公司法司法续造的方法论基础。在宏观原则即:信奉统一的司法哲学、审慎理性的司法裁量、实施性效果前瞻性考量的指导下, 对于法律漏洞的克服, 进行类别化识别与填补。 While centered around the theme of judicial development of company law against the macro-background characteristic of perfecting legislation and weakening jurisdiction, this dissertation presents an exploring research on the mechanism ensuring a positive reactive relationship and smooth dialogue between statute company law and jurisdiction thereof.The current research focuses on how jurists who bear the responsibility of forwarding decisions in specific cases by way of syllogism, interpret and develop company law in the absence of statute law adequately applicable to cases in hand ? Based on the legislative obstacles of the Company Law, like time lag, technicality and autonomy, judiciary has to create law for the incompleteness of the Company Law. In this process, it is the bottom of judicial intervention that should be concerned to be defended, which not only cannot threaten the existence of the spirit of company autonomy but also cannot to stifle the functions of company autonomy. Empirical methods are adopted in this research, in combination with the achievements by other scholars worked on related themes, the latest theoretical developments and overseas practices in similar areas as well, to deal with the challenges specified above. The purported purpose of this research is to work out a uniform mechanism for structuring a general theory on the theme so as to solve problems with respect to conflicts between decisions among individual cases, to find a way out of the dilemma between dynamic judicial innovations and the stability of legislation, and also to fill up the gap between company law theories and judicial practices and the leaks in statute company law. Based on the analysis of the influencing factors of judicial renewing, the article promotes the methodology foundation of the judicial renewing in Company Law. The macroscopic principle: under the guidance of believing in uniform judicial philosophy, prudent and rational discretion and foresight examination for implementation effect, it is through the categorized recognition and padding that the legal loopholes can be overcame.

      • KCI등재

        Role of Transcutaneous Electrical Nerve Stimulation in Treating Children With Overactive Bladder From Pooled Analysis of 8 Randomized Controlled Trials

        Huanqin Cui,Yi Yao,Zhunan Xu,Zhenli Gao,Jitao Wu,Zhongbao Zhou,Yuanshan Cui 대한배뇨장애요실금학회 2020 International Neurourology Journal Vol.24 No.1

        Purpose: Transcutaneous electrical neural stimulation (TENS), as a non-invasive modality, has been clinically used as an alternative treatment for children with overactive bladder (OAB). We conducted a pooled analysis to explore the effect of TENS on OAB. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-analysis guideline was followed in this study. The MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases, as well as the reference lists of the retrieved studies, were used to find trials relevant for assessing the use of TENS to treat OAB. Results: Of the 246 records identified, 8 publications were analyzed in our study. Our analysis found that TENS resulted in a greater decrease of wet days/wk, daily voiding frequency, daily incontinence episodes, and daily number of voids than was observed in the control group. Furthermore, TENS-treated patients showed similar visual analogue scale (VAS) scores to patients in the control group, demonstrating that the application of TENS did not increase patients’ discomfort and pain. TENS had a relative advantage in the number of partial responses, but no clear differences were found in frequency of no response or a full response compared to the control group. In urodynamic testing, TENS led to obvious improvements in average voided volume and maximum voided volume in children with OAB. Conclusions: TENS had a remarkable effect on the improvement of urodynamic indexes and objective OAB symptoms without a significant increase in VAS scores for children with OAB.

      • KCI등재

        The Cultural Content of Chinese ESL Textbooks in the EIL Context

        Claire Cui Wu,Hyo-young Kim 한국중원언어학회 2022 언어학연구 Vol.- No.65

        The present study examines Chinese high school English textbooks to see what cultural content is contained in the textbooks and whether they reflect EIL (English as an International Language) perspectives, by adopting Cortazzi and Jin’s distinction of cultural types, Moran’s 4P cultural dimensions and Song’s identification of intercultural interaction. The results indicate that the textbooks manifest a wide variety of cultural content. However, cultural types and cultural dimensions are distributed unevenly. The target cultures of English-speaking countries are predominantly represented, while international cultures that belong neither to the target culture nor the users’ home culture are overtly overlooked. Among Morans’ 4P of cultural aspects, cultural products are presented much more than practice, perspective, and person. Given the deficiencies of international perspectives, English textbook development in the future should involve more non-native experts from diverse cultural backgrounds. Professionals in the ELT field should shift to the EIL paradigm. Teachers are suggested to complement more materials with diverse cultural sources and carry out more intercultural activities so that the intercultural communicative competence becomes internalized in the context of EIL context.

      • SCIESCOPUSKCI등재

        Effects of Vitamin D Supplementation on Children with Autism Spectrum Disorder: A Systematic Review and Meta-analysis

        Min Zhang(Min Zhang),YiRan Wu(YiRan Wu),ZhaoXu Lu(ZhaoXu Lu),MeiYan Song(MeiYan Song),XiaoLan Huang(XiaoLan Huang),LaLa Mi(LaLa Mi),Jian Yang(Jian Yang),Xiaodai Cui(Xiaodai Cui) 대한정신약물학회 2023 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.21 No.2

        The effect of vitamin D supplementation on individuals with autism spectrum disorder (ASD) is inconclusive. We aimed to conduct a meta-analysis of the available randomized controlled trials (RCTs) to explore whether vitamin D supplementation can improve core symptoms and coexisting conditions in children with ASD. Data were obtained by searching the PubMed, Embase, Web of Science, CINAHL and Cochrane Library databases up to February 2022 following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Using a random-effects model, mean differences with 95% confidence intervals (CIs) were calculated through a meta-analysis. There were eight RCTs with 266 children with ASD in the present review, among which six RCTs were included in the meta-analysis. Children who received vitamin D supplementation showed a significant improvement in stereotypical behavior scores (pooled mean difference (MD): −1.39; 95% CI: −2.7, −0.07; p = 0.04) with low heterogeneity (I2 = 34%), and there was a trend toward decreased total scores on the Social Responsiveness Scale (SRS) and Childhood Autism Rating Scale (CARS, p = 0.05); however, there were no other significant differences in the core symptoms of ASD and coexisting conditions between groups as measured by the Aberrant Behavior Checklist (ABC). Vitamin D supplementation appears to improve stereotypical behaviors but does not improve other core symptoms and coexisting conditions. Further randomized controlled trials with large sample sizes and individualized doses are needed.

      • Anti-neuroinflammatory Activity of Nobiletin on Suppression of Microglial Activation

        Cui, Yanji,Wu, Jinji,Jung, Sung-Cherl,Park, Deok-Bae,Maeng, Young-Hee,Hong, Jeong Yun,Kim, Se-Jae,Lee, Sun-Ryung,Kim, Soon-Jong,Kim, Sang Jeong,Eun, Su-Yong Pharmaceutical Society of Japan 2010 BIOLOGICAL & PHARMACEUTICAL BULLETIN Vol.33 No.11

        <P>A growing body of evidence suggests that nobiletin (5,6,7,8,3′,4′-hexamethoxy flavone) from the peel of citrus fruits, enhances the damaged cognitive function in disease animal models. However, the neuroprotective mechanism has not been clearly elucidated. Since nobiletin has shown anti-inflammatory effects in several tissues, we investigated whether nobiletin suppresses excessive microglial activation implicated in neurotoxicity in lipopolysaccharide (LPS)-stimulated BV-2 microglia cell culture models. Release of nitric oxide (NO), the major inflammatory mediator in microglia, was markedly suppressed in a dose-dependent manner following nobiletin treatment (1—50 μ<SMALL>M</SMALL>) in LPS-stimulated BV-2 microglia cells. The inhibitory effect of nobiletin was similar to that of minocycline, a well-known microglial inactivator. Nobiletin significantly inhibited the release of the pro-inflammatory cytokine tumor necrosis factor (TNF-α) and interleukin-1β (IL-1β). LPS-induced phosphorylations of extracellular signal-regulated kinase (ERK), c-Jun NH<SUB>2</SUB>-terminal kinase (JNK), and p38 mitogen-activated protein kinases (MAPKs) were also significantly inhibited by nobiletin treatment. In addition, nobiletin markedly inhibited the LPS-induced pro-inflammatory transcription factor nuclear factor κB (NF-κB) signaling pathway by suppressing nuclear NF-κB translocation from the cytoplasm and subsequent expression of NF-κB in the nucleus. Taken together, these results may contribute to further exploration of the therapeutic potential and molecular mechanism of nobiletin in relation to neuroinflammation and neurodegenerative diseases.</P>

      • SCIESCOPUSKCI등재

        Dieckol Attenuates Microglia-mediated Neuronal Cell Death via ERK, Akt and NADPH Oxidase-mediated Pathways

        Cui, Yanji,Park, Jee-Yun,Wu, Jinji,Lee, Ji Hyung,Yang, Yoon-Sil,Kang, Moon-Seok,Jung, Sung-Cherl,Park, Joo Min,Yoo, Eun-Sook,Kim, Seong-Ho,Ahn Jo, Sangmee,Suk, Kyoungho,Eun, Su-Yong The Korean Society of Pharmacology 2015 The Korean Journal of Physiology & Pharmacology Vol.19 No.3

        Excessive microglial activation and subsequent neuroinflammation lead to synaptic loss and dysfunction as well as neuronal cell death, which are involved in the pathogenesis and progression of several neurodegenerative diseases. Thus, the regulation of microglial activation has been evaluated as effective therapeutic strategies. Although dieckol (DEK), one of the phlorotannins isolated from marine brown alga Ecklonia cava, has been previously reported to inhibit microglial activation, the molecular mechanism is still unclear. Therefore, we investigated here molecular mechanism of DEK via extracellular signal-regulated kinase (ERK), Akt and nicotinamide adenine dinuclelotide phosphate (NADPH) oxidase-mediated pathways. In addition, the neuroprotective mechanism of DEK was investigated in microglia-mediated neurotoxicity models such as neuron-microglia co-culture and microglial conditioned media system. Our results demonstrated that treatment of anti-oxidant DEK potently suppressed phosphorylation of ERK in lipopolysaccharide (LPS, $1{\mu}g/ml$)-stimulated BV-2 microglia. In addition, DEK markedly attenuated Akt phosphorylation and increased expression of $gp91^{phox}$, which is the catalytic component of NADPH oxidase complex responsible for microglial reactive oxygen species (ROS) generation. Finally, DEK significantly attenuated neuronal cell death that is induced by treatment of microglial conditioned media containing neurotoxic secretary molecules. These neuroprotective effects of DEK were also confirmed in a neuron-microglia co-culture system using enhanced green fluorescent protein (EGFP)-transfected B35 neuroblastoma cell line. Taken together, these results suggest that DEK suppresses excessive microglial activation and microglia-mediated neuronal cell death via downregulation of ERK, Akt and NADPH oxidase-mediated pathways.

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