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Park, S R,Kong, S-Y,Nam, B-H,Choi, I J,Kim, C G,Lee, J Y,Cho, S J,Kim, Y W,Ryu, K W,Lee, J H,Rhee, J,Park, Y-I,Kim, N K Nature Publishing Group 2011 The British journal of cancer Vol.104 No.7
<P><B>Background:</B></P><P>We evaluated the association between polymorphisms of cytochrome P450 2A6 (<I>CYP2A6</I>)/excision repair cross-complementation group 1 (<I>ERCC1</I>)/X-ray repair cross-complementing group 1(<I>XRCC1</I>) and treatment outcomes of metastatic gastric cancer (MGC) patients treated with S-1/cisplatin.</P><P><B>Methods:</B></P><P>Among MGC patients (<I>n</I>=108), who received S-1 (40 mg m<SUP>−2</SUP> b.i.d., days 1–14) and cisplatin (60 mg m<SUP>−2</SUP>, day 1) every 3 weeks, we analysed the wild-type allele (<I>W</I>) and variants (<I>V</I>) of <I>CYP2A6</I> (<I>*4</I>, <I>*7, *9, *10</I>), and the polymorphisms of <I>ERCC1</I> (rs11615, rs3212986) and <I>XRCC1</I> (rs25487).</P><P><B>Results:</B></P><P>Patients having fewer <I>CYP2A6</I> variants had better response rates (<I>W</I>/<I>W vs W</I>/<I>V</I> other than <I>*1/*4 vs V</I>/<I>V</I> or <I>*1/*4</I>=66.7 <I>vs</I> 58.3 <I>vs</I> 32.3% <I>P</I>=0.008), time to progression (TTP) (7.2 <I>vs</I> 6.1 <I>vs</I> 3.5 months, <I>P</I>=0.021), and overall survival (23.2 <I>vs</I> 15.4 <I>vs</I> 12.0 months, <I>P</I>=0.004). <I>ERCC1 19442C</I>><I>A</I> (rs3212986) was also associated with response rate (<I>C/C</I>, 46.7% <I>vs C/A</I>, 55.3% <I>vs A/A</I>, 87.5%) (<I>P</I>=0.048) and TTP (4.4 <I>vs</I> 7.6 <I>vs</I> 7.9 months) (<I>P</I>=0.012). Patients carrying both risk genotypes of <I>CYP2A6</I> (<I>V</I>/<I>V</I> or <I>1/*4</I>) and <I>ERCC1 19442C</I>><I>A</I> (<I>C/C</I>) <I>vs</I> those carrying none showed an adjusted odds ratio of 0.113 (<I>P</I>=0.004) for response, and adjusted hazard ratios of 3.748 (<I>P</I>=0.0001) for TTP and 2.961 (<I>P</I>=0.006) for death.</P><P><B>Conclusion:</B></P><P>Polymorphisms of <I>CYP2A6</I> and <I>ERCC1 19442C</I>><I>A</I> correlated with the efficacy of S-1/cisplatin.</P>
조병욱(Cho B W),이용찬(Lee Y C),고백진(Koh B J),최창완(Choi C W) 대한구강악안면외과학회 1991 대한구강악안면외과학회지 Vol.17 No.2
The analysis of soft tissue profile is an important paramenter in the esthetic aspect of facial deformity correction. The authors have studied on the soft tissue changes after the orthognathic surgery. We grouped the 30 patients according to the operation methods ; group 1 S.S.R.O. only, group 2 S.S.R.O.+Genioplasly, group 3 LeFortⅠ+S.S.R.O. The results were obtained as follows ; 1. In Group 1, the ratio of horizontal changes of hard tissue to soft tissue at 1 to Stmi, B to Si, Pog/SPog is 1.09, 0.96, 1.12 with postop. immediately, 0.98, 0.89, 0.98 with postop. 6 months. 2. In Group 2, the ratio of horizontal changes of hard tissue to soft tissue at 1/t Stmi, B/Si, Pog/SPog is 1.09, 1.11, 1.12 with postop. immediately, 0.92, 0.88, 0.99 with postop. 6 months. 3. In Group 3, the ratio of horizontal changes of hard tissue to soft tissue at A to Sn, 1 to Stms, B to Si, Pog to SPog is 1.15, 1.09, 1.15, 0.89, 1.05 with postop. immediately, 0.98, 0.94, 0.99, 0.90, 0.93 with pstop. 6 months.
Y.S. Cho,Y.B. Kim,W.S. Park,C.S. Kim,T.K. Kim 한국자기학회 1995 韓國磁氣學會誌 Vol.5 No.5
The influence of Nd and B contents on the magnetic properties and structures of α-Fe based Nd-(Fe, Co)B-Mo-Cu alloys was investigated. Nd₄(Fe_(0.9)Co_(0.1))_(92-x)BxMo₃Cu₁ and Nd_x(Fe_(0.9)Co_(0.1))_(86-x)B_(10)Mo₃Cu₁ amorphous alloys prepared by rapid solidification process were crystallized to form nanocrystalline structure. The increase of B content in Nd₄(Fe_(0.9)Co_(0.1))_(92-x)BxMo₃Cu₁ nanocrystalline resulted in the change of structure of soft phase in the sequence of α-Fe → α-Fe+Fe₃B → Fe₃B. The coercivitis of the alloys were increased with increasing B content and was 263 kA/m at x=18. On the contrary, the remanence has shown an opposite trends. The increase of Nd content in Nd_x(Fe_(0.9)Co_(0.1))_(86-x)B_(10)Mo₃Cu₁ nanocrystalline containing α-Fe as main phase had no effect on the structure and improved coercivity up to 256 kA/m. However, the remanence was decreased from 1.4 T to 1.15 T according to the increase of Nd content.
Ndx(Fe0.9Co0.1)90-xB6Nb₃Cu₁(x=3, 4, 5) 초미세결정립합금의 자기특성
조용수(Y. S. Cho),김만중(M. J. Kim),천정남(Z. N. Qian),김택기(T. K. Kim),박우식(W. S. Park),김윤배(Y. B. Kim) 한국자기학회 1995 韓國磁氣學會誌 Vol.5 No.5
Magnetic properties of Nd_x(Fe_(0.9)Co_(0.1))_(90-x)B_6Nb₃Cu₁(X = 3, 4, 5) melt-spun alloys with 6 at% B content were studied aiming for finding out a new α-Fe based Nd-Fe-B nanocrystalline alloy with good hard magnetic properties. Nd_x(Fe_(0.9)Co_(0.1))_(90-x)B_6Nb₃Cu₁ melt-spun alloys prepared by RSP crystallized to nanocrystalline phase. An optimally annealed Nd₃(Fe_(0.9)Co_(0.1))_(87)B_6Nb₃Cu₁ melt-spun alloys had larger volume ratio of α-Fe (Co) than that of higher Nd content alloy and showed high remanence of about 1.6 T. On the contrary, the increase of Nd content in Nd_x(Fe_(0.9)Co_(0.1))_(90-x)B_6Nb₃Cu₁ alloys gave rise to gradual increase of an amount of Nd₂(Fe, Co)₁₄B phase and improved coercivity. An optimally annealed Nd_5(Fe_(0.9)Co_(0.1))_(85)B_6Nb₃Cu₁ alloy showed the most improved hard magnetic properties. The remanence, coercivity and energy product of the alloy were 1.35 T, 219 ㎄/m (2.75 kOe), and 129 kJ/㎥ (16.2 MGOe), respectively.
Chip inductor용 Co₂Z type Ba - ferrite의 저온소결에 관한 연구
조균우(K. W. Cho),한영호(Y. H. Han),문병철(B. C. Moon) 한국자기학회 2002 韓國磁氣學會誌 Vol.12 No.5
Low temperature sintering of Co₂Z type Ba ferrites with various oxide additives has been studied. Co₂Z phase was obtained by 2 step calcination and XRD peaks showed a good agreement with the peaks of the standard Co₂Z phase, except for some minor extra peaks. ZnO-B₂O₃ glass, ZnO-B₂O₃ and CuO, ZnO-B₂O₃ and Bi₂O₃, and ZnO-Bi₂O₃ glass were added to lower sintering temperatures. Specimens were sintered at the temperature range between 900℃ and 1000℃. In the single addition of ZnO-B₂O₃ glass, the specimen with 7.5 wt% showed the highest shrinkage. Specimens with complex addition of ZnO-B₂O₃ glass with CuO or Bi₂O₃ showed higher shrinkages and initial permeabilities than single addition of ZnO-B₂O₃ glass. Shrinkages and initial permeabilities of the specimens with ZnO-Bi₂O₃ glass were higher than those of ZnO-B₂O₃ glass addition.
Shi, C. B.,Seo, M. D.,Cho, J. W.,Kim, S. H. Springer Verlag 2014 Metallurgical and materials transactions. B, Proce Vol.45 No.3
Crystallization behaviors of the newly developed lime-alumina-based mold fluxes for high-aluminum transformation induced plasticity (TRIP) steels casting were experimentally studied, and compared with those of lime-silica-based mold fluxes. The effects of mold flux crystallization characteristics on heat transfer and lubrication performance in casting high-Al TRIP steels were also evaluated. The results show that the crystallization temperatures of lime-alumina-based mold fluxes are much lower than those of lime-silica-based mold fluxes. Increasing B2O3 addition suppresses the crystallization of lime-alumina-based mold fluxes, while Na2O exhibits an opposite effect. In continuous cooling of lime-alumina-based mold fluxes with high B2O3 contents and a CaO/Al2O3 ratio of 3.3, faceted cuspidine precipitates first, followed by needle-like CaO center dot B2O3 or 9CaO center dot 3B(2)O(3)center dot CaF2. In lime-alumina-based mold flux with low B2O3 content (5.4 mass pct) and a CaO/Al2O3 ratio of 1.2, the formation of fine CaF2 takes place first, followed by blocky interconnected CaO center dot 2Al(2)O(3) as the dominant crystalline phase, and rod-like 2CaO center dot B2O3 precipitates at lower temperature during continuous cooling of the mold flux. In B2O3-free mold flux, blocky interconnected 3CaO center dot Al2O3 precipitates after CaF2 and 3CaO center dot 2SiO(2) formation, and takes up almost the whole crystalline fraction. The casting trials show that the mold heat transfer rate significantly decreases near the meniscus during the continuous casting using lime-alumina-mold fluxes with higher crystallinity, which brings a great reduction of surface depressions on cast slabs. However, excessive crystallinity of mold flux causes poor lubrication between mold and solidifying steel shell, which induces various defects such as drag marks on cast slab. Among the studied mold fluxes, lime-alumina-based mold fluxes with higher B2O3 contents and a CaO/Al2O3 ratio of 3.3 show comparatively improved performance.
14.6 A GeV ^28Si 중이온이 원자핵건판내에서 발생시킨 핵반응에서 생성된 2차입자의 발생각 분포
김종오,김태연,남신우,신택수,우종관,이세병,임계엽,장세덕,조재희,천병구,임인택,김기영 慶尙大學校 기초과학연구소 1990 基礎科學硏究所報 Vol.6 No.-
14.6A GeV^28Si 중이온이 원자핵 건판내에서 발생시킨 N_h=1인 핵반응에서 생성된 47개의 파쇄 α 입자와 537개의 단일하전 2차입자의 발생각들을 측정하여 변수 exp(γ-η_b)의 포괄적 분포를 회귀함수 dN=exp[a+χ{exp(γ-η_b)d{exp(γ-η_b)}로 적합시켰다. 여기서 의사신속도 γ=arctanh(cosθ)=-ln tan(θ/2)이고, 입사 중이온의 신속도 η_b=3.445이다. 그 적합결과 파쇄 α입자의 경우 χ=-0.052±0.011이고, 파쇄 p입자의 경우 χ=-0.141±0.015이었다. For LS emission angles of 47 α fragments and 537 single-charged shower particles, produced by the N_h (the number of heavyprongs)=1 interactions of 14.6 A GeV^28Si nuclei in the nuclear emulsion, the distribution of the parameter exp(γ-η_b) is well expressed by dN=exp[a+χ{exp(γ-η_b)d{exp(γ-η_b)}with χ=-0.052±0.011 for αfragments and χ=-0.141±0.015 for p 'fragments', where the pseudorapidity of secondaries γ=arctanh(cosθ)=-ln tan(θ/2) and the rapidity of incident heavy ions, η_b=3.445.