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Kim Hyung Woo,Min Jinsoo,Choi Joon Young,Shin Ah Young,Myong Jun-Pyo,Lee Yunhee,Yim Hyeon Woo,Jeong Hyunsuk,Bae Sanghyuk,Shim Eunhye,In Hyekyung,Chun Chaemin,Kim Gahee,Kang Ji Young,Lee Sung-Soon,Park 대한의학회 2021 Journal of Korean medical science Vol.36 No.36
In 2017, the Korean government launched an unprecedentedly large-scaled latent tuberculosis infection (LTBI) screening project which covered more than a million individuals in congregate settings. A total of 1,047,689 participants of source population (n = 2,336,157) underwent LTBI testing from 2017 to 2018. The overall LTBI test uptake rate during this project was 44.8%. Workers in daycare centers (83.5%) and kindergartens (78.9%) showed high participation rate. A total of 1,012,206 individuals with valid results of interferongamma release assay (IGRA) were selected to constitute the IGRA cohort. Most of the enrolled participants in the IGRA cohort were in their working age. Approximately, threequarters of total enrolled population were female. Investigating the LTBI prevalence, stages of LTBI care cascade, natural history of LTBI, efficacy of LTBI treatment and cost-effectiveness of LTBI screening are feasible within this IGRA cohort.
Column Chromatography-Free Solution-Phase Synthesis of a Natural Piper-Amide-like Compound Library
Kim, Sumin,Lim, Chaemin,Lee, Sukjin,Lee, Seokwoo,Cho, Hyunkyung,Lee, Joo-Youn,Shim, Dong Sup,Park, Hee Dong,Kim, Sanghee American Chemical Society 2013 ACS combinatorial science Vol.15 No.4
<P>We have achieved an efficient solution-phase parallel synthesis of a library of natural piper-amide-like compounds from the bifunctional β-phosphono-<I>N</I>-hydroxy-succinimidyl ester intermediate. The primary important feature in our study is the construction of natural-product-like molecules through the adaptation of sophisticated organic reactions that create water-soluble byproducts for a chromatography-free purification. This simple and efficient method rapidly provides a combinatorial library of high yield and purity. The library was evaluated against GPCR targets to demonstrate its potential use as a tool for drug discovery and in chemical biology.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/acsccc/2013/acsccc.2013.15.issue-4/co400003d/production/images/medium/co-2013-00003d_0009.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/co400003d'>ACS Electronic Supporting Info</A></P>
Kim, Seok-Soon,Chun, Chaemin,Hong, Jae-Chul,Kim, Dong-Yu Royal Society of Chemistry 2006 Journal of materials chemistry Vol.16 No.4
<P>Well-ordered TiO<SUB>2</SUB> nanostructures such as 1-dimensional nanowire arrays, 2-dimensional square and hexagonal hole arrays, and 3-dimensional wire junction arrays were fabricated by a simple, controllable, economical, and reproducible method using surface relief gratings on azobenzene-functionalized polymer films as a template in the sol–gel reaction of a Ti precusor. In addition, as an application of TiO<SUB>2</SUB> nanostructure, transparent electrodes were patterned by selective dry etching with the TiO<SUB>2</SUB> nanowire array etch mask. Scanning electron microscope and atomic force microscope images confirmed the successful formation of a variety of well-ordered TiO<SUB>2</SUB> nanostructures and nanopatterning of transparent electrodes.</P> <P>Graphic Abstract</P><P>Well-ordered TiO<SUB>2</SUB> nanostructures such as 1D nanowire arrays, 2D square and hexagonal hole arrays, and 3D wire junction arrays were fabricated using surface relief gratings on azobenzene-functionalized polymer films as a template in the sol–gel reaction. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b512104c'> </P>
김동현(Kim, DongHyun),김형규(Kim, HyeongGyu),정동호(Jung, DongHo),진필근(Jin, PhilGeun),한채민(Han, ChaeMin) 한국IT서비스학회 2016 한국IT서비스학회 학술대회 논문집 Vol.2016 No.추계
기존에 PowerShell은 윈도우 서버와 호스트를 관리하는 용도로 일부 관리자들 사이에서 사용되어 왔다. 그러나 Microsoft에서 제공하는 PowerShell은 시스템 관리 외에도 많은 강력한 기능을 제공한다. 현재 국내 IR업체들의 경우 네트워크 패킷이나 IDS의 로그를 이용하여 사후 대응 서비스를 제공하는 경우는 존재하지만 ESM의 한 분야로써 PowerShell을 활용한 서비스를 제공하는 업체는 극히 일부이다. 해외의 경우에도 PowerShell을 이용한 IR서비스 업체가 존재하지만 침입 지점만을 특정해줄 뿐 이에 대한 보고서를 작성할 수있는 수준까지의 정보를 제공하고 있지 않은 것으로 보인다. 본 논문에서는 가시화적인 요소와 더불어 최대한 신속하게 발생 사건의 구체적인 윤곽을 그릴 수 있도록 참고 정보를 제공하는 서비스를 제안한다.
측두근 피판(Temporalis muscle flap)을 이용한 뇌척수액 누출(CSF leakage)환자의 치료 : 증례보고
김채민(Chaemin Kim),윤인식(Insik Yun),이원재(Wonjae Lee),김용욱(Yongoock Kim),유대현(Daehyun Lew) 대한두개저학회 2013 대한두개저학회지 Vol.8 No.2
Cranial defect can occur after trauma or tumor resection, subsequently leading to CSF leakage. When there is CSF leakage with a subtle dural tear or small defect, it can be managed by observation or endoscopic treatment. However, if the defect is large, it should be reconstructed by a regional flap or free flap. Temporalis muscle flap is favorable for reconstruction of a large defect due to its sufficient volume and reliable blood suply.?In addition, by using the reverse temporalis muscle, extension to the anterior cranial base is possible, which is useful for CSF leakage due to cranial defect. We report a case using temporalis muscle flap and a case?using reverse temporalis muscle flap with a review of literature.