A Rational Entry to Cyclic Polymers via Spontaneous and Selective Cyclization Reactions

Daisuke Aoki 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.1

Although recent advances in chemistry have made it possible to synthesize polymers with various topologies, effective routes that selectively afford cyclic topology in high yield and quantity still remain limited. This is mostly due to difficulties associated with purification, and, in particular, the selectivity of macrocyclizations. In this work, effective synthetic methods for the cyclic polymers were developed by utilizing supramolecular chemistry¹ and dynamic covalent chemistry.² (1) D. Aoki et al., J. Am. Chem. Soc., 139, 6791 (2017). (2) D. Aoki et al., Angew. Chem. Int. Ed., 59, 4269 (2020).

Analysis of the Subjective Difficulty of Instructors Giving Instructions on Clinical Training for Nurses in Regard to the Relationship between Air Pressure and Airflow

Hisae Aoki,Mayumi Monji,Naoko Aoki,Maki Miyoshi,Keiko Kubota 한국간호과학회 2015 한국간호과학회 학술대회 Vol.2015 No.10

Validation of HPV triage in cytology- based cervical cancer screening for ASC-US cases using Japanese data

Eiko Saitoh Aoki,Kumiko Saika,Kazushige Kiguchi,Tohru Morisada,Daisuke Aoki 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.2

Objective: In Japan, cervical cancer screening consists of a cytology examination performed once every 2 years. We verified whether the risk of cervical intraepithelial neoplasia (CIN) 3 disease or higher (CIN3+) was equivalent to that of cytology negative cases (negative for intraepithelial lesion or malignancy [NILM]) for patients with a cytological diagnosis of “atypical squamous cells of undetermined significance (ASC-US)” who tested negative for human papillomavirus (HPV). Methods: Data from a total of 22,925 cases who had undergone cervical cancer screening at least twice or who had completed follow-up examinations after cervical screening at a single facility between April 2013 and April 2018 were analyzed. The cumulative incidence of CIN3+ was calculated for each category of initial cytology finding and HPV result (NILM, > ASC-US, ASC-US/HPV (unknown), ASC-US/HPV+, and ASC-US/HPV−). The statistical analysis was conducted using the Cox proportional hazards model. Results: The hazard ratio for the cumulative incidence of CIN3+ in 2 years relative to that for NILM cases was 2.7 (95% confidence interval=1.0–7.8) for > ASC-US cases, 0.5 (0.1–1.7) for ASC-US/HPV (unknown), 0.8 (0.3–2.4) for ASC-US/HPV+ cases, and 0.3 (0.1–1.0) for ASC-US/HPV− cases. Conclusion: Because the cumulative incidence of CIN3+ at 2 years for the ASC-US/HPV− cases was sufficiently low, compared with that of the NILM cases, we considered it reasonable and safe to perform HPV triage for ASC-US cases and to allow HPV-negative cases to return for their next screening in 2 years, which is the same follow-up schedule as that for NILM cases.

The Oribatid Mites (Acari: Cryptostigmata) of Korea (4) On the femoralis-group of the genus Carabodes C.L, Koch, 1836

Park, Seong-Sik,Aoki, Jun-ichi 한국곤충학회 1986 Korean journal of entomology Vol.16 No.1

한국산 날개응애류중에서 검둥이응애과(Caratodiidae)에 속하는 무늬검둥이응애 (Carabodes transversarius sp. n.)와 어깨점둥이응애 (C. tsushimaensis dorsalis subsp. n.)를 신종으로 기재하고 대마도 검둥이응애 (C. tsushimaensis Aoki, 1970)를 미기록종으로 기록하며 Caradodes속의“femoralis group”의 종검색표를 작성하였다. Two new species and one unrecorded species of Korean oribatid mites belonging to the genus Car-aboder C. L. Koch, 1836 (Carabodiidae) are described. They are C. transversarius sp. nov., C. tsu shimaensis dorsalis subsp. nov. and C. tsushimaensis Aoki, 1970. A Key to the species of“femoralis group”of the genus Caradodes is presented.

韓國產 날개응애類(3) Defectamerus 屬의 新種에 關하여

SEONG SIK CHOI,JUN-ICHI AOKI 한국응용곤충학회 1985 한국응용곤충학회지 Vol.24 No.3

Defectamerus soonkii sp. nov. and D. crassisetiger coreanus subsp. nov. belonging to the family Ameridae are described. Key to the species of the genus Defectamerus Aoki is presented. 한국산(韓國産) Defectamerus속(屬)의 1 신종(新種), 1 신아종(新亞種) 및 종검색표(種檢索表)를 작성(作成)하였다. 신종(新種)은 순기민동정응애(D. soonkii sp. nov.)와 신아종(新亞種)으로 한국민동정응애(D. crassisetiger coreanus subsp. nov.)를 기재(記載)하였다.

Postoperative norepinephrine versus dopamine in patients undergoing noncardiac surgery: a propensity-matched analysis using a nationwide intensive care database

Aoki Yoshitaka,Nakajima Mikio,Sugimura Sho,Suzuki Yasuhito,Makino Hiroshi,Obata Yukako,Doi Matsuyuki,Nakajima Yoshiki 대한마취통증의학회 2023 Korean Journal of Anesthesiology Vol.76 No.5

Background: Choosing catecholamines, such as norepinephrine and dopamine, for perioperative blood pressure control is essential for anesthesiologists and intensivists. However, studies specific to noncardiac surgery are limited. Therefore, we aimed to evaluate the effects of postoperative norepinephrine and dopamine on clinical outcomes in adult noncardiac surgery patients by analyzing a nationwide intensive care patient database.Methods: The Japanese Intensive care PAtient Database (JIPAD) was used for this multicenter retrospective study. Adult patients in the JIPAD who received norepinephrine or dopamine within 24 h after noncardiac surgery in 2018–2020 were included. We compared the norepinephrine and dopamine groups using a one-to-one propensity score matching analysis. The primary outcome was in-hospital mortality. Secondary outcomes were intensive care unit (ICU) mortality, hospital length of stay, and ICU length of stay.Results: A total of 6,236 eligible patients from 69 ICUs were allocated to the norepinephrine (n = 4,652) or dopamine (n = 1,584) group. Propensity score matching was used to create a matched cohort of 1,230 pairs. No differences in the in-hospital mortality was found between the two propensity score matched groups (risk difference: 0.41%, 95% CI [−1.15, 1.96], P = 0.608). Among the secondary outcomes, only the ICU length of stay was significantly shorter in the norepinephrine group than in the dopamine group (median length: 3 vs. 4 days, respectively; P < 0.001).Conclusions: In adult patients after noncardiac surgery, norepinephrine was not associated with decreased mortality but was associated with a shorter ICU length of stay than dopamine.

Measurement of Barium Ion Displacement Near Surface in a Barium Titanate Nanoparticle by Scanning Transmission Electron Microscopy

Aoki, Mai,Sato, Yukio,Teranishi, Ryo,Kaneko, Kenji Korean Society of Microscopy 2018 Applied microscopy Vol.48 No.1

Barium titanate ($BaTiO_3$) nanoparticle is one of the most promising materials for future multi-layer ceramic capacitor and ferroelectric random access memory. It is well known that electrical property of nanoparticles depends on the atomistic structure. Although surface may possibly have an impact on the atomistic structure, reconstructed structure at the surface has not been widely investigated. In the present study, Ba-ion position near surface in a $BaTiO_3$ nanoparticle has been quantitatively characterized by scanning transmission electron microscopy. It was found that some Ba ions at the surface were greatly displaced in non-uniform directions.

The Concept of the 'Launching State' Revisited

Aoki, Setsuko 한국항공우주법학회 2002 한국항공우주정책·법학회지 Vol.15 No.-

Commercialization and privatization of outer space has been developing to the extent that public space law regime established at the UN seems to be somewhat incompatible with the today's commercial launching services. Thus, this paper analyzes, at first, the UN space treaties to specify the obstacles for promoting commercial use. The necessity of some covert amendment of UN treaties is suggested through the national space legislation. Then three state practices are examined to propose a new concept of the "launching state" including the Sea Launch project, since the concept of the "launching state" is of the major importance to enact an effective national act to better accommodate UN space treaties to the present necessity.

Structural identification and seismic performance of brick chimneys, Tokoname, Japan

Aoki, T.,Sabia, D. Techno-Press 2005 Structural Engineering and Mechanics, An Int'l Jou Vol.21 No.5

Dynamic and static analyses of existing structures are very important to obtain reliable information relating to actual structural properties. For this purpose a series of material test, dynamic test and static collapse test of the existing two brick chimneys, in Tokoname, are carried out. From the material tests, Young's modulus and compressive strength of the brick used for these chimneys are estimated to be 3200 MPa and 7.5 MPa, respectively. The results of static collapse test of the existing two brick chimneys are discussed in this paper and composed with the results from FEA (Finite Element analysis). From the results of dynamic tests, the fundamental frequencies of Howa and Iwata brick chimneys are estimated to be about 2.69 Hz and 2.93 Hz, respectively. Their natural modes are identified by ARMAV (Autoregressive Moving Average Vectors) model. On the basis of the static and dynamic experimental tests, a numerical model has been prepared. According to the European code (Eurocode n. 8: "Design of structures for earthquake resistance") non-linear static (Pushover) analysis of the two chimneys is carried out and they seem to be vulnerable to earthquakes with 0.25 to 0.35 g.

Damage propagation in CFRP laminates subjected to low velocity impact and static indentation

Aoki, Yuichiro,Suemasu, Hiroshi,Ishikawa, Takashi The Korean Society for Composite Materials 2007 Advanced composite materials Vol.16 No.1

This paper describes a damage accumulation mechanism in cross-ply CFRP laminates $[0_2/90_2]_{2S}$ subjected to out-of-plane loading. Drop-weight impact and static indentation tests were carried out, and induced damage was observed by ultrasonic C-scan and an optical microscope. Both tests gave essentially the same results for damage modes, sizes, and load-deformation history. First, a crack occurred in the bottom $0^{\circ}$ layer accompanying some delamination along the crack caused by bending stress. Then, transverse cracks occurred in the middle $90^{\circ}$ layer with decreasing contact force between the specimen and the indenter. Measured local strains near the impact point showed that the stress state changed from a bending dominant state to an in-plane tensile dominant state. A cohesive interface element was used to simulate the propagation of multiple delaminations and transverse cracks under static indentation. Two types of analytical models are considered, one with multiple delaminations and the other with both multiple delaminations and transverse cracks. The damage obtained for the model with only multiple delaminations was quite different from that obtained from the experiment. However, the results obtained from the model with both delaminations and transverse cracks well explain the characteristics of the damage obtained in the experiment. The existence of the transverse cracks is essential to form the characteristic impact damage.