Adaptive Fault Tolerant Stabilization for Uncertain MIMO Systems with Actuation Failures

Wanqin Xiang,Wei Ao,Yiyuan Chen 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.5

This paper considers the state stabilization problem for a class of non-affine uncertain MIMO systems with actuation failures. An adaptive robust fault-tolerant control is developed to compensate the affect of uncertainties, actuator failures. And theoretical analysis based on a Lyapunov-like approach demonstrates that, under some proper conditions, the close-loop system would be stabilized and ultimately uniformly bounded state error could be guaranteed by the controller. Further, the proposed controller is no need for on-line fault detection and diagnosis unit, and inexpensive to compute. At last, numerical simulations are provided to validate and illustrate the benefits and effectiveness of the proposed control scheme.

Effects of non-genetically and genetically modified organism (maize-soybean) diet on growth performance, nutrient digestibility, carcass weight, and meat quality of broiler chicken

Song Zhang,Xiang Ao,김인호 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.6

Objective: This study was conducted to compare growth performance, nutrient digestibility and meat quality of broilers fed a genetically modified organism (GMO) diet or a non-GMO diet. Methods: A total of 840 broilers with an initial body weight of 43.03 g per chick were randomly allocated into 1 of the following 2 dietary treatments lasted for 32 days (15 broilers per pen with 28 replicates per treatment): i) Trt 1, GMO maize-soybean meal based diet; ii) Trt 2, non-GMO maize soybean meal based diet. Both diets were maize-soybean meal diets. The GMO qualitative analysis, proximate analysis and amino acid analysis of the feed ingredient samples were carried out. Diets were formulated based on a nutrient matrix derived from analysis results. Growth performance was measured on day 0, 7, 17, and 32. And all other response criteria were measured on day 32. Results: The analysis results showed that the total Lys, Met, Thr of non-GMO grains were lower than that of GMO grains, the protein content of GMO soybean meal was higher than that of non-GMO soybean meal. Feed intake and feed conversion rate (FCR) were greater (p<0.05) in broilers provided with non-GMO diet than that of the GMO group from d 17 to 32. A decrease in FCR was observed in birds fed the GMO diet through the entire experiment (p<0.05). No significant impacts on blood profile, meat quality and nutrient digestibility were found in response to dietary treatments throughout the experimental period (p>0.05). Conclusion: These results indicated that non-GMO diet showed a negative effect on growth performance but nutrient digestibility, blood profile, carcass weight and meat quality were not affected by non-GMO diets.

Clusterin negatively modulates mechanical stress-mediated ligamentum flavum hypertrophy through TGF-β1 signaling

Liu Chunlei,Li Peng,Ao Xiang,Lian Zhengnan,Liu Jie,Li Chenglong,Huang Minjun,Wang Liang,Zhang Zhongmin 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

Ligamentum flavum hypertrophy (LFH) is a major cause of lumbar spinal canal stenosis (LSCS). The pathomechanisms for LFH have not been fully elucidated. Isobaric tags for relative and absolute quantitation (iTRAQ) technology, proteomics assessments of human ligamentum flavum (LF), and successive assays were performed to explore the effect of clusterin (CLU) upregulation on LFH pathogenesis. LFH samples exhibited higher cell positive rates of the CLU, TGF-β1, α-SMA, ALK5 and p-SMAD3 proteins than non-LFH samples. Mechanical stress and TGF-β1 initiated CLU expression in LF cells. Notably, CLU inhibited the expression of mechanical stress-stimulated and TGF-β1-stimulated COL1A2 and α-SMA. Mechanistic studies showed that CLU inhibited mechanical stress-stimulated and TGF-β1-induced SMAD3 activities through suppression of the phosphorylation of SMAD3 and by inhibiting its nuclear translocation by competitively binding to ALK5. PRKD3 stabilized CLU protein by inhibiting lysosomal distribution and degradation of CLU. CLU attenuated mechanical stress-induced LFH in vivo. In summary, the findings showed that CLU attenuates mechanical stress-induced LFH by modulating the TGF-β1 pathways in vitro and in vivo. These findings imply that CLU is induced by mechanical stress and TGF-β1 and inhibits LF fibrotic responses via negative feedback regulation of the TGF-β1 pathway. These findings indicate that CLU is a potential treatment target for LFH.

Exploratory Study: A Modification Training Method of Attentional Bias Toward Safety

Gao, Jingqi,Wu, Xiang,Luo, Xiaowei,Zhang, Ao Occupational Safety and Health Research Institute 2021 Safety and health at work Vol.12 No.3

Background: The high sensitivity of individuals toward safety information in production activities, that is, attentional bias toward safety (ABS), can positively predict safe behaviors. It has become a hot topic in current organizational safety behavior research. However, there is no literature on its modification method. Methods: Based on the modified dot-probe task, we designed a modification training method of ABS. The training method required subjects to respond to the location of detection points that presented after safety stimulus and neutral stimulus pictures. Subjects' attentional bias values of safety and neutral pictures were measured during the experiment. Twenty-one students were selected and divided into a control group and training group to gain comparable results. Results: A novel training method was developed in this study to promote the efficacy of safety stimulus by activating ABS of the subjects. Moreover, repeated trainings and preacquired relative knowledge can enhance this effect. Conclusion: This study develops an experimental approach to evaluate the effectiveness of safety education and safety training, and also provides a new research idea for accident prevention.

Effects of dietary probiotic, liquid feed and nutritional concentration on the growth performance, nutrient digestibility and fecal score of weaning piglets

Zhang Song,Yoo Dong Huy,Ao Xiang,김인호 아세아·태평양축산학회 2020 Animal Bioscience Vol.33 No.10

Objective: This study was conducted to investigate the effects of dietary probiotic blend and liquid feed program at different nutritional densities on growth performance, nutrient digestibility, fecal score of weaning piglets. Methods: A total of 120 weaning pigs with an initial body weight of 7.05±0.93 kg per pig (21 days of age) were randomly allocated into 1 of the following 8 dietary treatments (3 replicates per treatment with 5 pigs per replicate) in a 2×2×2 factorial arrangement (nutrition levels: apparent metabolic energy [AME] = 3,500 kcal/kg, crude protein [CP] = 20% vs AME = 3,400 kcal/kg, CP = 19.42%; feed types:dry vs wet; probiotics levels: 0 mg/kg vs 300 mg/kg). Results: During d 5 to d 15, greater average daily gain (ADG) and average daily feed intake (ADFI) (p<0.05) were observed in probiotics treatments. During d 15 to d 25, gain:feed (G:F) ratio (p<0.05) were significantly improved in probiotics, wet feed and high nutrition diet. Moreover, two interactions i) between nutrition levels and feed types, and ii) between nutrition levels and probiotics were found in G:F ratio. Furthermore, there was a significant positive interaction on G:F among those 3 factors (p<0.05). Overall, increasing ADG, ADFI, and G:F ratio were detected in probiotics treatment significantly (p<0.05). Besides, an obvious reduction on fecal score was observed in probiotics treatment from d 0 to d 5 (p<0.05). There was an interactive effect on fecal score between feed types and nutrition concentrations from d 5 to d 25 (p<0.05). Conclusion: These results indicated that probiotics supplementation could benefit growth performance and reduce the frequency of watery feces. Besides, wet feed program (feed:water = 1:1.25) could improve the G:F. The effect of liquid feed or probiotic could be influenced by dietary nutrition density in weaned piglets. An increased value of G:F was obtained when wet feeding a high nutrition diet (100 kcal higher than NRC 2012 recommendations) was supplemented with probiotics for 15 to 25 days.

Covered Stenting Is an Effective Option for Traumatic Carotid Pseudoaneurysm with Promising Long-Term Outcome

Wang, Kai,Peng, Xiao-xin,Liu, Ao-fei,Zhang, Ying-ying,Lv, Jin,Xiang, Li,Liu, Yun-e,Jiang, Wei-jian The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.5

Objective : Covered stenting is an optional strategy for traumatic carotid pseudoaneurysm, especially in malignant conditions of potential rupture, but the long-term outcomes are not clear. Our aim was to determine if covered stenting is an effective option for traumatic carotid pseudoaneurysm with promising long-term outcomes. Methods : Self-expanding Viabahn and balloon-expandable Willis covered stents were separately implanted for extra- and intracranial traumatic carotid pseudoaneurysm. The covered stent was placed across the distal and proximal pseudoaneurysm leakage under roadmap guidance. Procedural success was defined as technical success (complete exclusion of the pseudoaneurysm and patency of the parent artery) without a primary end point (any stroke or death within 30 days after the procedure). Long-term outcomes were evaluated as ischemic stroke in the territory of the qualifying artery by clinical follow-up through outpatient or telephone consultation and as the exclusion of the pseudoaneurysm and patency of the parent artery by imaging follow-up through angiography. Results : Five patients with traumatic carotid pseudoaneurysm who underwent covered stenting were enrolled. The procedural success rate was 100%. No ischemic stroke in the territory of the qualifying artery was recorded in any of the five patients during a mean clinical follow-up of 44±16 months. Complete exclusion of the pseudoaneurysm and patency of the parent artery were maintained in all five patients during a mean imaging follow-up of 39±16 months. Conclusion : Satisfactory procedural and long-term outcomes were obtained, suggesting that covered stenting is an effective option for traumatic carotid pseudoaneurysm.

The Effect of Impeller Indent Distance on the Performance of Vortex Pumps

Lei DAI,Lei GU,Jun WANG,Xiang AO,Xiaobo ZHU 한국유체기계학회 2020 International journal of fluid machinery and syste Vol.13 No.1

Low efficiency is an urgent problem to be solved for vortex pumps due to large number of vortices and backflows. This paper concentrates on the performance improvement of vortex pumps caused by changing the indent distance of the impeller. First, a complete numerical model was established by selecting the optimal length of inlet and outlet and appropriate mesh quantity. Then, the reliability of this model was validated by comparing simulation results with experimental data. Based on this model, the internal flows of vortex pumps with different impeller indent distances were observed in simulations and the fitted curves of head and efficiency were created. Finally, the cause of the performance improvement was demonstrated by analyzing the flow field in vortex pumps.

Covered Stenting Is an Effective Option for Traumatic Carotid Pseudoaneurysm with Promising Long-Term Outcome

Kai Wang,Xiao-xin Peng,Ao-fei Liu,Ying-ying Zhang,Jin Lv,Li Xiang,Yun-e Liu,Wei-jian Jiang 대한신경외과학회 2020 Journal of Korean neurosurgical society Vol.63 No.5

Objective : Covered stenting is an optional strategy for traumatic carotid pseudoaneurysm, especially in malignant conditions of potential rupture, but the long-term outcomes are not clear. Our aim was to determine if covered stenting is an effective option for traumatic carotid pseudoaneurysm with promising long-term outcomes. Methods : Self-expanding Viabahn and balloon-expandable Willis covered stents were separately implanted for extra- and intracranial traumatic carotid pseudoaneurysm. The covered stent was placed across the distal and proximal pseudoaneurysm leakage under roadmap guidance. Procedural success was defined as technical success (complete exclusion of the pseudoaneurysm and patency of the parent artery) without a primary end point (any stroke or death within 30 days after the procedure). Longterm outcomes were evaluated as ischemic stroke in the territory of the qualifying artery by clinical follow-up through outpatient or telephone consultation and as the exclusion of the pseudoaneurysm and patency of the parent artery by imaging follow-up through angiography. Results : Five patients with traumatic carotid pseudoaneurysm who underwent covered stenting were enrolled. The procedural success rate was 100%. No ischemic stroke in the territory of the qualifying artery was recorded in any of the five patients during a mean clinical follow-up of 44±16 months. Complete exclusion of the pseudoaneurysm and patency of the parent artery were maintained in all five patients during a mean imaging follow-up of 39±16 months. Conclusion : Satisfactory procedural and long-term outcomes were obtained, suggesting that covered stenting is an effective option for traumatic carotid pseudoaneurysm.