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Significant Domains of Life Satisfaction That Affect Suicidal Behavior in Adolescents
Ji Soo Kim,Seo-Hyun Choi,Sang-Eun Lee,Chai Won Lee,Won-Hyoung Kim,Jae Nam Bae,Jeong Seop Lee,Seri Maeng,Jisung Son,Hyeyoung Kim 대한소아청소년정신의학회 2021 소아청소년정신의학 Vol.32 No.3
Objectives: Adolescent suicide is a serious national issue in Korea. Recently, life satisfaction has been recognized as a major factor related to this issue. The main purpose of this study was to identify the domains of life satisfaction that affect suicidal behavior in adolescence. Methods: Data were collected from eight middle schools in Incheon, Korea. A total of 1297 students answered questions regarding their demographic characteristics, happiness, self-related life satisfaction domains (appearance, leisure time, physical health, and mental health), depressive symptoms, and suicidal behavior. Results: In the Spearman correlation analysis, female sex, perceived socioeconomic status (SES), happiness, and all four self-related satisfaction scores showed significant correlations with depression and suicidality. Multivariate regression analysis suggested that suicidality was significantly affected by perceived SES, satisfaction with appearance, mental health satisfaction, and depression. Finally, depression was identified as a partial mediator of the association between mental health satisfaction and suicidality, and a complete mediator of the association between female sex and suicidality. Conclusion: Perceived SES, satisfaction with appearance, and mental health satisfaction significantly affected students’ suicidality, with or without the effect of depression. Health authorities, educators, and family members must be aware of this to identify adolescents at suicide risk earlier.
Alternative skin irritation test using the MCTT skin model
( Ji Young Moon ),( Jin Hee Lee ),( Eun Ho Maeng ),( Hak Soo Park ),( Min Kwon ),( Dong Hyouk Jang ),( Young Min Cho ),( Eun Ok Koh ),( Ha Jung Sung ),( Cheol Beom Park ) 한국동물실험대체법학회 2007 한국동물실험대체법학회 학술대회집 Vol.2007 No.1
Reconstructed skin give advantages to single cell culture testing system and leads to promising results as be shown in different validation studies. In this study we investigated the efficacy of MCTT Skin model compared with in vivo test. We conducted endpoint analysis including cell viability and IL-1 alpha release. Sodium lauryl sulfate(20%), Potassium hydoxide(5%), Heptanal, Methyl palmitate, 1,1,1-Trichloroethane, 2,4-Xylidine, 3,3`-Dithiodipropionic acid, 4-Amino-1,2,4-triazol and Benzyl chloroformate were selected for this comparison. Potassium hydoxide(5%) and Benzyl chloroformate were excluded from animal tests because of their pH. Sodium lauryl sulfate induced severe irritation, Heptanal induced moderate irritation. Methyl palmitate, 1,1,1-Trichloroethane induced mild irritation. 2,4-Xylidine, 3,3`-Dithiodipropionic acid, 4-Amino-1,2,4-triazole induced no irritation on rabbit skin irritation test. Except Methyl palmitate and 2,4-Xylidine, the results were same between MCTT Skin model and in vivo skin irritation test. According to other studies, the results of other skin model and in vivo test of Methyl palmitate and 2,4-Xylidine were shown different result each other. Thus, we concluded that this MCTT Skin model is useful for alternative skin irritation test, although other tests should be conducted for many other chemicals in international validation study.
영산강 하구호 Network 유출해석을 위한 SSARR-SWMM 연계모형 개발
박지성 ( Ji-sung Park ),최지영 ( Ji-yeong Choi ),맹승진 ( Seong-jin Maeng ),김진수 ( Jin-soo Kim ) 한국농공학회 2017 한국농공학회 학술대회초록집 Vol.2017 No.-
The Streamflow Synthesis and Reservoir Regulation model(SSARR) is an computerized watershed model. Storm Water Management Model(SWMM) is used for analysis related to stormwater runoff in urban areas. The purpose of this study is to develop an integrated SSARR-SWMM model to simulate water level and discharge in the estuary lakes network, and examine the applicability of the model. The model was applied to estuary lakes network in Youngsan River watershed, which was recently redeveloped with increased drainage gates and widened connecting canals. The highest water levels in Youngsan Lake and Youngam Lake during flood season after redevelopment were much lower than those before redevelopment. The highest water levels in Youngsan Lake and Geumho Lake during flood season for lake-connected operation were much lower than those for individual operation. Those mean that floods in the lakes are greatly reduced by redevelopment or lake-connected operation. The water levels in Youngsan Lake and Youngam Lake for highly controlled water levels were much higher than those for current controlled water levels. The result shows that additional water use volume can be secured by heightening controlled water level. The model will be used for establishing integrated water management system of Youngsan River watershed.
Kim, Ji-Hyun,Chang, Sung Man,Hong, Jin Pyo,Bae, Jae Nam,Cho, Seong-Jin,Hahm, Bong-Jin,Lee, Dong-Woo,Park, Jong-Ik,Lee, Jun-Young,Jeon, Hong Jin,Kim, Byung-Soo,Cho, Maeng Je Elsevier 2016 Journal of affective disorders Vol.203 No.-
<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Patients with subthreshold bipolar disorder (Sub-BP) experience severe clinical courses and functional impairments which are comparable to those with bipolar I and II disorders (BP-I and -II). Nevertheless, lifetime prevalence, socioeconomic correlates and diagnostic overlaps of bipolar spectrum disorder (BPS) have not yet been estimated in the general population of South Korean adults.</P> <P><B>Methods</B></P> <P>A total of 3013 adults among the 2011 Korean Epidemiologic Catchment Area survey (KECA-2011) completed face-to-face interviews using the Korean versions of the Composite International Diagnostic Interview 2.1 and Mood Disorder Questionnaire (K-CIDI and K-MDQ).</P> <P><B>Results</B></P> <P>The lifetime prevalence of BPS in the South Korean adults was measured to be 4.3% (95% CI 2.6–6.9). Nearly 80% of the subjects with BPS were co-diagnosed with other DSM-IV non-psychotic mental disorders: 35.4% (95% CI 24.2–48.5) for major depression and dysthymic disorder, 35.1% (95% CI 27.7–43.3) for anxiety disorders, and 51.9% (95% CI 40.5–63.1) for alcohol and nicotine use disorders. Younger age (18–34 years) was the only sociodemographic predictor of BPS positivity (<I>P</I>=0.014), and the diagnostic overlap patterns were different between men and women.</P> <P><B>Limitations</B></P> <P>The prevalence of BPS and other mental disorders could have been influenced by recall bias due to the retrospective nature of this study.</P> <P><B>Conclusions</B></P> <P>Positivity for BPS was estimated to be much greater than the prevalence of DSM-IV BP in South Korea. Most of the respondents with BPS were diagnosed with other major mental disorders and this might be related with mis- and/or under-diagnosis of clinically relevant Sub-BP.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The lifetime prevalence of bipolar spectrum disorder (BPS) is 4.3% in South Korea. </LI> <LI> Younger age (18-24 years) is a significant predictor of BPS in South Korea. </LI> <LI> Nearly 80% of people with BPS could be diagnosed of other mental disorders. </LI> <LI> There are gender differences in diagnostic overlap pattern of BPS in South Korea. </LI> </UL> </P>
Kang, Ji Yeon,Lee, Jae Sung,Kang, Hyejin,Lee, Hae-Woo,Kim, Yu Kyeong,Jeon, Hong Jin,Chung, June-Key,Lee, Myung Chul,Cho, Maeng Je,Lee, Dong Soo RAVEN PRESS PUBLISHERS 2012 ALZHEIMER DISEASE AND ASSOCIATED DISORDERS Vol.26 No.3
The aim of this study was to identify brain areas related to apathy or depression in patients with Alzheimer disease (AD). Eighty-one AD patients were enrolled in this prospective study. Tc-HMPAO single photon emission computed tomography was performed to evaluate regional cerebral blood flow (rCBF). According to the Neuropsychiatric Inventory subscores of apathy and depression, 9 patients were classified as clinically significant (cs) depressed and non-cs-apathetic (D+) groups and 9 were classified as cs-apathetic and non-cs-depressed (A+) groups. In addition, 18 patients were classified as age-matched and Mini-Mental State Examination-matched disease control groups (D−, A−). The significance of rCBF differences between groups and the correlation between rCBF and subscores in 81 AD patients were estimated by SPM (uncorrected P<0.005) analysis. D+ patients had significantly lower perfusion in the right orbitofrontal and inferior frontal gyri than D− patients, whereas A+ patients had this in the right amygdala, temporal, posterior cingulate, right superior frontal, postcentral, and left superior temporal gyri than A− patients. The negatively correlated areas with depression subscores included the left inferior frontal and the right middle frontal gyri and those with apathy subscores included the right temporal and right medial frontal gyri. We suggest that this finding may indicate that apathy and depression in AD patients involve distinct functional circuits.
홍지영 ( Ji Young Hong ),이상국 ( Sang Kook Lee ),조용진 ( Yong Jin Cho ),김철진 ( Chul Jin Kim ),김남수 ( Nam Soo Kim ),김종태 ( Chong Tai Kim ),맹진수 ( Jin Soo Maeng ) 한국산업식품공학회 2012 산업 식품공학 Vol.16 No.1
Strawberries have various fruit phenolics which provide biological activities such as antioxidant, anti-inflammatory, and anti-proliferative potential against various cancer cells. Previous studies showed that such phenolics might be enriched by ultraviolet irradiation (UV) after harvesting fruits and vegetables. In the present study, we investigated the effect of post-harvest ultraviolet irradiation on the biological activities of strawberries. When 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity, induction of quinone reductase activity, inhibitory effect on the proliferation of various human cancer cells, and inhibitory effect on the expression of inducible nitric oxide synthase (iNOS) of UV-irradiated strawberries using Maehyang, Akihime, and Red pearl, were evaluated, the biological activities were, in general, enhanced by ultraviolet irradiation after harvest.
문지영 ( Ji Young Moon ),맹은호 ( Eun Ho Maeng ),박학수 ( Hak Soo Park ),권민 ( Min Kwon ),장동혁 ( Dong Hyouk Jang ),조영민 ( Young Min Cho ),고은옥 ( Eun Ok Koh ),성하정 ( Ha Jung Sung ),박철범 ( Cheol Beom Park ) 한국동물실험대체법학회 2007 동물실험대체법학회지 Vol.1 No.1
Reconstructed skin provides advantages to single cell culture testing and leads to promising results as shown by different validation studies. In this study we investigated the efficacy of MCTT Skin model compared with EPI-200 and in vivo test. We conducted endpoint analysis including cell viability (MTT reduction, CCK-8) and IL-1 alpha release. Sodium lauryl sulfate(20%), Potassium hydoxide(5%), Heptanal, Methyl palmitate, 1,1,1-Trichloroethane, 2,4-Xylidine, 3,3`-Dithiodipropionic acid, 4-Amino-1,2,4-triazol and Benzyl chloroformate were selected for this comparison. Potassium hydoxide(5%) and Benzyl chloroformate were excluded from animal tests because of their pH. Sodium lauryl sulfate induced severe irritation, Heptanal induced moderate irritation. Methyl palmitate, 1,1,1-Trichloroethane induced mild irritation. 2,4-Xylidine, 3,3`-Dithiodipropionic acid, 4-Amino-1,2,4-triazole induced no irritation on rabbit skin irritation test. Results of MTT assay and CCK-8 assay were not different between EPI-200 MCTT Skin model but IL-lα levels of some test items different between EPI-200 and MCTT Skin model. We concluded that this MCTT Skin model is useful for alternative skin irritation test, although other tests should be conducted for many other chemicals in international validation study.