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2개 대학병원 응급센터에 내원한 급성 불화수소산 노출 환자에 대한 임상적 경험
한규홍,양중일,조성욱,조용철,유승,이진웅,김승환,유인술,유연호,박정수,Han, Kyu-Hong,Yang, Jung-Il,Jo, Seung-Yook,Cho, Yong-Chul,Ryu, Seung,Lee, Jin-Woong,Kim, Seung-Whan,Yoo, In-Sool,You, Yeon-Ho,Park, Jung-Soo 대한임상독성학회 2009 대한임상독성학회지 Vol.7 No.2
Purpose: We investigated the clinical characteristics and demographics of patients who suffered from hydrofluoric acid chemical injury and the mechanism of damage. Methods: We retrospectively reviewed the medical records of patients who were exposed to hydrofluoric acid from March 2004 to March 2009 and who were seen at the emergency centers in two university teaching hospitals. Results: Forty four patients out of 47 patients suffered from chemical burn, while the injuries of the remaining 3 could not be identified by the medical records. A total of 17 hydrofluoric acid chemical injury patients were enrolled during the study period, and their mean age was $29.6{\pm}7.0$. All the patients were accidentally injured by contact with the material and none of them inhaled or ingested the material. Only 6 patients wore appropriate protective equipments and 5 underwent the water irrigation for more than 10 minutes. The most common exposure area was the hand and forearm (70.5%). Less than 1% of all of the patients had their total body surface (TBS) exposed to hydrofluoric acid (mean=0.35%). The mean time interval from calcium gluconate administration to pain relief was $33.6{\pm}8.8$ hours. Conclusion: When exposed to hydrofluoric acid, it is important to wear protective equipment and undergo water irrigation for more than 10 minutes. Pain and skin damage were observed in all the patients. After treatment, we concluded that administration of calcium gluconate and pain killers was successful in relieving pain, and the prognosis was also positive for the admitted and followed up patients when less than 1% of the TBS was exposed.
한규홍(Kyuhong Han),김지환(Jihwan Kim),김현섭(Hyunsup Kim),박태호(Taeho Park),김지훈(Jihun Kim),홍정호(Jeongho Hong),이형철(Hyeongcheol Lee) 한국자동차공학회 2009 한국자동차공학회 부문종합 학술대회 Vol.2009 No.4
This paper presents the fault detection and isolation (FDI) strategy for a parallel hybrid electric vehicle (HEV). The powertrain of the target parallel HEV consists of an internal combustion engine, an integrated starter and generator (ISG), a traction motor, an ISG belt as a pulley system and an engine clutch between the engine and the traction motor. In this study, the model-based FDI algorithm for the current and the angle sensors in the ISG and the traction motor is developed. In the supervisory controller, another FDI algorithm is also developed through structural analysis of the ISG belt and the engine clutch. This FDI algorithm utilizes a powertrain model composed of five sub-models: the ISG, the ISG belt, the engine, the engine clutch and the traction motor. For the fault detection, analysis of the signal fluctuation during the faulty situation is performed for different scenarios. For getting the computer simulation results of the developed FDI strategy, the powertrain model and the controller of the target parallel HEV are developed to simulate the proposed FDI strategy. Validity and effectiveness of the proposed FDI strategy is shown by the simulation results.
6륜 전기구동 차량의 구성품 최소 용량 선정과 주행 성능 분석
한규홍(Kyuhong Han),여승태(Seungtai Yeo) 한국자동차공학회 2018 한국자동차공학회 학술대회 및 전시회 Vol.2018 No.11
Based on critical factors related to requirements, a reasonable design procedure is proposed to determine the minimum power capability of the components of a hybrid electric driving vehicle such as a battery, an electric motor, and an engine/generator. In this study, the procedure to satisfy the essential target driving performance is adapted for a six-wheeled hybrid electric driving vehicle of military application. And with a longitudinal vehicle dynamics, vehicle performance is analyzed to judge whether the target vehicle composed of the components of the selected size satisfies the target driving performance.
한규홍(Kyuhong Han),이태경(Taekyung Lee),정창모(Changmo Jung) 한국자동차공학회 2012 한국자동차공학회 학술대회 및 전시회 Vol.2012 No.11
This paper describe development process and results of a battery emulation system using power conversion unit. The battery emulation system can be a substitute for a real battery system in the test environment which is hard to use a real battery system. For developing this battery emulation system, a HIL(Hardware-In-the-Loop) simulator which has a realtime battery system model and a power conversion unit which supply real electric power are connected. The test result for comparison between the real battery system result and the battery emulation system result has similar tendency and values. It is possible to emulate battery characteristics if this battery emulation system is used in the developing process for electric propulsion systems.
고장 모사 기능을 포함한 군용 하이브리드 전기 자동차용 배터리 시스템 모델링
한규홍(Kyuhong Han),이윤복(Yoonbok Lee) 한국자동차공학회 2013 한국자동차공학회 부문종합 학술대회 Vol.2013 No.5
This paper describes the development process and results of a battery system model for military hybrid electric vehicles with fault simulation. The battery system model can be used to verify control and fault diagnosis strategies of a supervisory controller in the hybrid electric vehicle. To develop this battery system model, three sub-models, including a battery model, a relay assembly model, and a BMS(Battery Management System) model, are connected together similarly to real battery systems. The comparison result between the real battery system and the battery system model shows similar tendency and similar values. And fault injection test shows real system situation. It is possible to emulate battery characteristics and fault situation if this battery system model is used in the development process of the supervisory control strategies for hybrid or electric propulsion systems.
청국장 중 biogenic amine의 함량 및 생성원인
한규홍(Gyu-Hong Han),조태용(Tae-Yong Cho),유명상(Myung-Sang Yoo),김천수(Chun-Soo Kim),김정민(Jung-Min Kim),김현아(Hyun-Ah Kim),김미옥(Mi-Ok Kim),김성철(Seong-Cheol-Kim),이선애(Sun-Ae Lee),고용석(Yong-Suk Ko),김소희(So-Hee Kim),김대병(Da 한국식품과학회 2007 한국식품과학회지 Vol.39 No.5
본 연구에서는 청국장에서 biogenic amine의 함량을 조사하고, 이를 생성하는 미생물의 스크리닝 및 biogenic amine 형성 등을 통하여 생성원인을 규명하고자 하였다. 그 결과 국내 시판 청국장에는 putrescine, histamine, tryptamine 등 11종의 biogenic amine이 검출되었으며, 이 중 tyramine이 4.2±0.9-483.1±28.4 mg/kg의 범위를 보여주여 다른 amine에 비하여 높게 나타났다. 청국장내 균주는 B. amyloliquefaciens, B. subtilis, B. licheniformis 등이 분리?동정되었고, 이들 균주에 대한 탈탄산 효소 활성 스크리닝을 살펴본 결과 모두 양성(+) 반응을 보여주었다. 최종적으로 균주에 대한 biogenic amine 생성을 확인하였을 때, 청국장내 존재하는 균주가 탈탄산 효소 활성을 통하여 biogenic amine 생성하는 것을 확인할 수 있었다. The potential to produce biogenic amines was investigated in microbial strains isolated from fermented soybean paste, cheonggukjang. The typical levels of 11 biogenic amines, including putrescine, histamine, and tryptamine, were analyzed in commercial cheonggukjang. The tyramine and histamine levels in the samples ranged from 4.2 to 483.1 mg kg<sup>-1</sup> and 0.2 to 70.3 mg kg?1, respectively. A total of 4 microbial strains of Bacillus sp. were isolated from cheonggukjang. The Bacillus sp. were identified as B. amyloliquefaciens, B. subtilis, and B. licheniformis based on phenotypic characteristics, which included using the VITEK system. The screening plate method for detecting amino acid decarboxylase positive microorganisms was performed. The results for amine decarboxylation were positive, and biogenic amine formation was evaluated by the confirmation of amine-forming capacity.
한규홍(Gyu-Hong Han),김병용(Byung-Yong Kim) 한국식품영양과학회 2003 한국식품영양과학회지 Vol.32 No.8
두유박과 옥분 혼합물의 압출성형물을 제조하기 위한 공정 조건의 위하여 스크류 속도 150~250 rpm, 혼합물의 수분함량 20~30%, 온도 100~150℃의 조건에서 압출성형하고, 반응표면분석법(RSM)을 이용하여 최적조건을 분석하였다. 공정 조건에 따른 팽화율에서는 스크류 속도가 높고 수분함량이 낮을수록 팽화가 크게 일어났고, 수분함량이 많을수록 용적밀도를 높이는 것으로 나타났다. 절단강도의 경우 수분함량에 따라 감소하다 증가하는 추세를 보여주었고, WSI는 스크류 속도와 수분함량에 WAI는 수분함량과 온도에 많은 영향을 받았다. 색도에서는 b값을 제외하고는 유의적인 차이를 보이지 않았다. 각 조건별 실험결과를 반응표면분석을한 결과 팽화율과 용적밀도, WSI, b값은 linear 모델로 결정되었고, 절단강도와 WAI는 quadratic 모델이 유의성을 나타내었다. 압출성형 공정의 최적화는 결정된 반응식과 반응표면 그래프를 이용한 결과 수치 최적화에서는 스크류 속도 250 rpm, 수분함량 22.43%, 온도 128.16℃이었고, 모형적 최적화에서는 desirability가 0.727인 스크류 속도 250 rpm, 수분함량 22.43%, 온도 128.02℃로 결정되었다. The extrusion conditions of the soymilk residue and corn grits mixtures were optimized. The experiment was designed according to the D-optimal design of response surface methodology (RSM), which shows 18 experimental points including 4 replicates for three independent variables (screw speed, water content and die temperature). The responses variables such as bending force, expansion ratio, bulk density, water solubility index (WSI), water absorption index (WAI), and color values (L, a, b) were evaluated using response surface analysis. Expansion ratio and WSI decreased with increasing water content, whereas bulk density tended to increase with increasing water content. While greater screw speeds enhanced WSI and yellowness, higher moisture contents decreased the expansion ratio and WSI value. However, die temperature did not influence upon the response variables. The optimum extrusion conditions by numerical and graphical methods were similar: the screw speed, water content, and die temperature were 250 rpm, 22.43% and 128.16℃ by the numerical method; 250 rpm, 22.43%, and 128.02℃ by graphical method.