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마라톤이 건강한 중년남성의 RBP4와 CRP변화에 미치는 영향
채지숙,김성민,이정아,전용관 대한비만학회 2014 The Korean journal of obesity Vol.23 No.3
배경: 본 연구는 급성유산소운동으로 구성된 1회성 마라톤(42.195km) 달리기가 건강한 중년남성의 Retinol Binding Protein 4 (RBP₄)및 C-reactive protein (CRP)와 생리학적 혈액성분에 어떠한 영향을미치는가를 규명하는 데 목적이 있다. 방법: 본 연구의 대상자는 인터넷 마라톤 동호회 사이트에서 연구공지를 통해 모집하였고, 당뇨병력이 없는 40-50대 중년남성 총 14명이연구에 참여하였다. 운동군(N= 8)은 과거 마라톤을 완주한 경험이있고, 과거에 마라톤에 참여한 경험이 없는 건강한 중년남성으로 대조군(N= 6)을 구성하였다. 운동군만 마라톤을 완주하였고, 대조군은 마라톤에 참여하지 않고 휴식을 취하였다. 결과: 마라톤달리기(평균완주시간: 256.75±11.52 min)는 RBP₄ (pre:86.63±28.87 vs post: 92.22±42.20 μg/mL)와 CRP (pre: 0.04±0.04vs post: 0.04±0.04 mg/dL) 혈중 농도에 영향을 미치지 않았다. 그러나 마라톤달리기는 백혈구 수치(White blood cell, pre: 5.80±1.64 th/mm3, post: 13.62±3.62 th/mm3, P< 0.001)와 총 콜레스테롤(Totalcholesterol, pre: 177.38±41.79 mg/dL, post: 182.25±42.84 mg/dL,P< 0.05) 수치를 유의하게 증가시켰다. 결론: 1회성 급성유산소운동은 건강한 중년남성의 급성염증반응 인자인 WBC를 상승시켰지만, RBP₄와 CRP에는 영향을 미치지 않는것으로 나타났다. 추가적으로 마라톤 달리기와 관련된 WBC, RBP₄,CRP를 포함하는 생리학적 지표에 관한 연구가 지속되어야 한다.
최지숙,강경림,이근우,채송이 건강보험심사평가원 심사평가연구소 2021 연구보고서 Vol.2020 No.0
This has two purposes. Firstly, it explores how to apply treatment type scores for evaluating whether cases are appropriate for tertiary level of care. Secondly, it proposes improvement of a system of case-mix assessment by developing a method for severity assessment. For these purposes, we conducted literature reviews on designation standards of tertiary medical institutions in other countries. We convened an advisory council consisting of members of medical societies, healthcare service experts and policy makers, and developed a method for case-mix assessment for inpatients of tertiary hospitals. The assessment method either adopted an average admission treatment type score or developed scores with scaling from 60 to 100 for each medical institution. KDRG(Korea Diagnosis Related Group) corresponding to mental health and rehabilitation cases were excluded from the analysis. A severity assessment score was given between 0.6 to 1 point based on the ratio of severe emergency cases and severe-ill cases. We found that in case of the improvement measures being in place, some of current tertiary hospitals are expected to lose the designation status as tertiary hospitals while three new applicants are likely to be granted tertiary hospital designation. In the future, Items on the severity assessment list are needed to be expanded. A follow-up research is required to develop a patient-based assessment model which integrates inpatients and outpatients, who received medical services from tertiary hospitals.
비만한 중년 남성에서 열량제한과 운동을 통한 체중 감소의 효과
박현영,장양수,김오연,유하정,채지숙,이종호 대한비만학회 1999 The Korean journal of obesity Vol.8 No.2
$quot;Background: With abdominal obesity being recognized as an important risk factor of metabolic disease and atherosclerosis, it is important to determine the optimal weight loss program for decreasing this risk. The goal of this study was to determine beneficial health effects of modest weight loss with low calorie diet and exercise in middle-aged overweight Korean men. Method: Sixteen overweight men aged 40-49 years participated in a 3-month weight- management program. The diet and exercise program reduced daily energy intake by 300-400 kcal from daily energy need and expended about 100 kcal in walking and other light exercise. Compliance with the diet and exercise protocol was monitored through 7-day records of diet and physical activity maintained by subjects monthly. Adipose tissue and muscle areas were calculated from computerized tomography scans at 3 body levels, Ll, IA and mid portion of thigh before and after weight loss. Anthropometries, serum levels of lipids and hormones and response areas of glucose, C-peptide, insulin and free fatty acid during oral glucose tolerance test (OGTT) were determined. Result: After 3 months of diet and exercise, body weight fell an average of 4.9 kg (6.3%) and waist circumference reduced an average of Scm. Modest weight loss appeared to decrease blood pressure in overweight males. Although weight loss did not show any significant differences in thigh muscle and femoral subcutaneous fat areas, there was about 20% reduction in visceral, subcutaneous and total fat areas of Ll and L4 levels after weight loss. Mean values of serum total cholesterol, even though within normal range before weight loss, decreased significantly after weight loss. Serum triglyceride concentration fell from 192 to 143 mg/dL in association the loss of weight. Modest weight loss showed a 30% decrease in fasting insulin and response areas of insulin during OGTT. There was a 16% but not significant decrease in the response area of free fatty acid during OGTT after weight reduction. Conclusion: The result suggests that modest weight reduction with diet and exercise can show a rapid decrease in abdominal fat without muscle loss, compared with in femoral fat. Modest weight loss about 6% of initial weight can be viable apprach to help decrease serum lipids and hyperinsulinemia and improve insulin responsiveness to glucose challenge.
유하정 ( Yu Ha Jeong ),김오연 ( Kim O Yeon ),채지숙 ( Chae Ji Sug ),박현영 ( Park Hyeon Yeong ),이종호 ( Lee Jong Ho ),장양수 ( Jang Yang Su ) 한국지질동맥경화학회 ( 구 한국지질학회 ) 2002 韓國脂質學會誌 Vol.12 No.1
Background : We aimed to evaluate the differences in body fat distribution and the effects of high-fat meal on postprandial lipemia in normortriglyceridemic and hyper-triglyceridemic men who usually consume typical high carbohydrate diet. Methods : Sevent