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RISS 인기검색어
- 검색키워드
- 저자 : 조승렬(Seung Ryul Cho) (검색결과 3 건)
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간경변증과 원발성 간암 환자의 혈중 동과 아연에 관한 연구
안기완(Gi Wan An),김만우(Man Woo Kim),조건국(Kun Kook Cho),조승렬(Seung Ryul Cho),김만중(Man Jung Kim),김원학(Won Hak Kim) 대한내과학회 1987 대한내과학회지 Vol.33 No.3
N/A The copper and zinc concentrations were measured in sera of 28 cases of liver cirrhosis, 10 cases of liver cirrhosis with hepatocellular carcinoma, 17 cases of hepatocellular carcinoma and 48 normal control cases by atomic absorption spectrometer in Chosun University Hospital from July 1985 to July 1986. The result were as follows; 1) The mean concentrations of copper in serum of normal control and liver cirrhosis group were 96.03±5. 02, 86.61±7.98 ㎍/dl respectively, but in serum of hepatocellular carcinom a with and without liver cirrhosis the concentrations were each 123.74±13.04 and 127.93± 24.24 ㎍/dl, which were significantly higher than that of normal control group (p<0.001). 2) The mean concentration of zinc in serum of normal control group was 104.81±3.40 ㎍/dl, but in serum of liver cirrhosis, hepatocellular carcinoma with and without liver cirrhosis the concentrations were each 69.03±10.55, 76.01±11.12 and 58.72±12.65 ㎍/dl, which were significantly lower than the former (p<0.001). 3) The ratio of copper to zinc level in serum of normal control group was 0.940.06, but in serum of liver cirrhosis, hepatocellular carcinoma with and without liver cirrhosis the concentration-ratios were each 1.36±0.05, 1.65±0.03 and 2.34±0.59, which were higher than the former. But in serum of hepatocellular carcinoma with and without liver cirrhosis, the ratios of copper to zinc level were significantly higher than that of liver cirrhosis (p < 0,001). Consequently, in hepatocellular carcinoma with and without liver cirrhosis group, the serum copper levels were significantly higher in comparison with that of normal control group. In hepatocellular carcinoma with and without liver cirrhosis group, the serum zinc levels were significantly lower in comparison with that of normal control group. In hepatocellular carcinoma with and without liver cirrhosis, the ratios of copper to zinc level were significantly highter than that of normal control group, These findings demonstrate the usefulness of these parameters as the diagnostic aid in patients with hepatocellular carcinoma.
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고혈압 허혈성 심질환에서 혈청 Apolipoprotein의 변화에 관한 연구
조승렬,안기완,장경식,정춘해,홍순표,조건국 朝鮮大學校 附設 醫學硏究所 1987 The Medical Journal of Chosun University Vol.12 No.1
The overwhelming evidence that low density lipoprotein (LDL) plays a major role and high density lipoprotein (HDL) plays a preventive role in cardiovascular disease is beyond refutation. Since the protein moiety of HDL and LDL is the most important determinant of its compositional and structural stability, attensions has turned to the estimation of HDL and LDL protein rather than cholesterol as an index of plasma HDL and LDL concentration. We measured and compared the levels of serum apolipoprotein A (apo-A), and apolipoprotein 13 (apo-B), HDL--cholesterol (HDL-C), total cholesterol, and triglyceride in control group and patients with hypertension and ischemic heart disease. The results arc summerized as follows. 1. In hvpetensive patients, the level of apo-A is significantly lower (p < 0. 00l) than control group, other levels shows no significant difference. 2. In patients with ischemic heart disease, the levels of apo-A and HDL-C are significantly lower (p < 0.001, p < 0.005, respectively) and apo-B and apo-B/apo-A are higher (p < 0.005, p < 0.001, respectively) than control group. Other lipid levels shows no significant difference. It seems that apo-A and apo-B/apo-A are more useful than apo-B and HDL-C for identifying ischemic heart disease.
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